The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS

[JohnJames]

Hi John

Do you late for does often???How long can you be late for and still continue the round???

Thanks

There's no exact line where it is ok and not ok to take a dose, but Andy suggested between an hour and an hour and a half late. I'm usually not later by 20 mins.

[15yrsAndCounting]

I did not understand what is ACC? Can someone explain please.
And what are the exact supplements that you guys are using , which is helping, can you guys please list it.

[JohnJames]

I did not understand what is ACC? Can someone explain please.
And what are the exact supplements that you guys are using , which is helping, can you guys please list it.

Step 1: Remove all possible sources of ongoing mercury poisoning.

Usually dental amalgam fillings are the culprit though not always, these need to be removed safely by a dentist who knows what they are doing, IE uses hazmat suits, oxygen, dental dam, amalgam cut out in chunks, room is properly isolated/ventilated. After/During procedure digital intraoral bitewings must be checked for specks of amalgam that may have been left behind and these too must be removed. Failure to properly follow this step will result in you not improving or getting worse.

Step 2: Get on the Core 4 supplements: Magnesium, Vit C, Zinc, Vit E.

Other supplements/diets can also help reduce symptoms but YMMV.

Step 3: 3 months after ALL source of mercury have been removed, Take Alpha Lipoic Acid ALA every 2-3 hrs for 63 hrs. Dose to symptoms. This is 1 round.

Usually people start between 0.25-12mg of ALA. Only increase your dose when you feel no difference on round and off round. Don't increase your dose by more than 50% at a time. Don't be afraid to reduce your dose if you feel rough.

Step 4: Rest minimum 3 days between rounds.

Step 5: Repeat Step 3 to 5 until all symptoms are gone for 6 months on a high enough dose (usually 200-300 mg ALA). This usually takes years (2-8 years).

I've currently done around 90 rounds and I've still got a while to go but I'm doing way way better.

Usually you'll feel better after removal of mercury sources, then after 3 months you might feel like your improvements stall or you start to feel worse again, then if you continue chelating, after a while you will start feeling better again. There is a "dump/stall" phase that occurs usually around 3-6 months, this is thought to happen once blood levels of mercury reduce enough such that intracellular mercury then starts to mobilize.

[Clues]

JohnJames, I'm currently detoxing with chlorella and cilantro, and considering adding alpha lipoic acid to the mix. I see you're quoting the ACC chelation protocol. The last time I looked into that (10 years back) there didn't seem to be a lot of solid science behind that particular protocol. Googling ALA and detoxing now, I'm seeing some promising papers, but I was wondering whether the ACC protocol itself has ever been tested against others? I mean, how do we know for sure that taking breaks in between "rounds" is important for example?

[DEANNX]

I have finished 12 rounds of ALA, I haven?t had orgasm for 2 and half months now but recently I been experiencing depression and insomnia and get upset stomach when I am on round, not sure if that is the sign of dump phase or some other factor.

[JohnJames]

JohnJames, I'm currently detoxing with chlorella and cilantro, and considering adding alpha lipoic acid to the mix. I see you're quoting the ACC chelation protocol. The last time I looked into that (10 years back) there didn't seem to be a lot of solid science behind that particular protocol. Googling ALA and detoxing now, I'm seeing some promising papers, but I was wondering whether the ACC protocol itself has ever been tested against others? I mean, how do we know for sure that taking breaks in between "rounds" is important for example?

Chlorella doesn't chelate. Cilantro we have no scientific method of dosing without avoiding redistribution as we don't understand it's pharmacokinetics. Both should be avoided ideally.

ACC was drawn up through interpretation of the literature on mercury removal, combined with the standard medical practice for dosing on a drugs pharmacokinetic half-life. There are many studies Andy cited which he drew from to form ACC.

Sure there are no Randomized Control Trials using ACC, but nor are their any for other methods of mercury removal. What ACC does have is thousands of people who have chelated and got better, no other method seems to boast the same amount of success.

If I remember correctly taking ALA increases bodily retention of copper taking the 3 day break allows the copper levels to settle, it's also why zinc is required to chelate, copper/zinc compete for the same receptors so taking one should reduce absorption of the other. We also know that redistribution of mercury takes around 3 days after chelating. This is verified theoretically, and backed by anecdotal experience.

Your questions are probably best directed to those on the ACC forums on facebook, there are people there whom are far more knowledgeable than me and a number of sources to read.

[Hopeoneday]

Chorella is potent naturall chelator:
https://www.google.com/search?client=firefox-b-d&q=is+chorela+chelator

But chorella cant penetrate in brain, thats why is used first to clean
toxins from body(NAC also wery potent),  then after that chelator for brain like chilantro or ALA.
learn about zeolite and odher chelators...
learn what is redistributinon when chelation start!
Learn what is binders and when to take them, like vit c ,
apple petcins etc...

[Clues]

JohnJames, thanks for your detailed response. I think it's been proven that chlorella does chelate mercury though, see this paper.

Hopeoneday, thanks for your input as well.

[JohnJames]

JohnJames, thanks for your detailed response. I think it's been proven that chlorella does chelate mercury though, see this paper.

Hopeoneday, thanks for your input as well.

Chlorella does not chelate, Chelators have very specific chemical properties which causes mercury to chemically bond to the chelator. You can look at a molecule and determine whether or not it will or won't form a bond with mercury. Chelate/Chelation the word has a very specific meaning, substances which remove mercury doesn't mean they chelate mercury.

Chemistry is not my field of expertise so can't tell you much more.

With regards to the study, the study does not show that Chlorella chelates because it physically can't, it also doesn't show that Chlorella detox's mercury. However, it doesn't show that it does not detox mercury either.

If you read the method carefully, you'll see that during the 90 days of supplementation the patients removed their fillings, which means they changed more than 1 variable during the course of the study. The control group also did not have any amalgam fillings. The supplements they used was an entire regime, not just Chlorella, one such supplement they used was Selenium which has documented interactions with mercury. The study also only took 1 sample at d0 and d90 and did not monitor mercury levels throughout the entire process.

In order to prove Chlorella was doing something my guess is they'd have to compare a control group whom remove their fillings vs a group whom remove their fillings and take Chlorella.

It also only looked at blood levels of mercury. Mercury in the blood has a relatively low half-life (in the weeks) anyway and naturally decreases after removing ongoing exposures. Cellular mercury and mercury in the brain we don't know the half-life but estimations put it in the decades.

[Clues]

Chlorella does not chelate, Chelators have very specific chemical properties which causes mercury to chemically bond to the chelator. You can look at a molecule and determine whether or not it will or won't form a bond with mercury. Chelate/Chelation the word has a very specific meaning, substances which remove mercury doesn't mean they chelate mercury.

Oh, I see. I need to read up on this more.

The control group also did not have any amalgam fillings.

It also only looked at blood levels of mercury. Mercury in the blood has a relatively low half-life (in the weeks) anyway and naturally decreases after removing ongoing exposures.

Argh, that's really disappointing. I need to learn some more medical lingo so I can read these things properly.

Chlorella has definitely reduced some of my symptoms though. I guess it could be that 1. it does remove mercury by some yet-unknown mechanism or 2. it's helping my body in some completely unrelated way.

Here is another paper looking at chlorella and mercury removal, does this look like real research? I don't have the full article unfortunately.

[DEANNX]

Hi John

I missed a late night does and had to stop the round then I wake up with brain fog is it normal? It kinda concerns me a little.

Thanks

Dean

[JohnJames]

Chlorella does not chelate, Chelators have very specific chemical properties which causes mercury to chemically bond to the chelator. You can look at a molecule and determine whether or not it will or won't form a bond with mercury. Chelate/Chelation the word has a very specific meaning, substances which remove mercury doesn't mean they chelate mercury.

Oh, I see. I need to read up on this more.

The control group also did not have any amalgam fillings.

It also only looked at blood levels of mercury. Mercury in the blood has a relatively low half-life (in the weeks) anyway and naturally decreases after removing ongoing exposures.

Argh, that's really disappointing. I need to learn some more medical lingo so I can read these things properly.

Chlorella has definitely reduced some of my symptoms though. I guess it could be that 1. it does remove mercury by some yet-unknown mechanism or 2. it's helping my body in some completely unrelated way.

Here is another paper looking at chlorella and mercury removal, does this look like real research? I don't have the full article unfortunately.

I think Chlorella is considered to be a binder, mercury and other things adsorb to the surface and in the gut which you then comes out in faeces. I would of thought other binders would also work such as Activated Charcoal. Problem is they just aren't going to remove mercury in the brain and in cells any more than would move naturally, which takes decades.

I think ACC actually thinks Chlorella is not harmful to take so doesn't have to be avoided, I think I misremembered in my post.

With all due respect Clues, how do you know some of the improvements you are having are from removing mercury exposure from your dental amalgams?

I don't have access to the full article so can't comment but from the abstract seems to confirm the above. The bit about mice seems very bizarre, looking at the pictures and reading the abstract.

Hi John

I missed a late night does and had to stop the round then I wake up with brain fog is it normal? It kinda concerns me a little.

Thanks

Dean

Yeah I have similar experiences when I miss doses.

[Clues]

With all due respect Clues, how do you know some of the improvements you are having are from removing mercury exposure from your dental amalgams?

Perfectly valid question JJ. I don't know for sure, it's just conjecture. There's more detail in my earlier posts in this thread, but basically I have symptoms that seems to match with mercury poisoning, and the chlorella immediately caused tingling and numbness in areas where I've had the most pain (jaw, lower back, feet), and over a few months it has alleviated some of my symptoms noticeably.

I'd welcome any tips on how to get myself tested.

Here is the full paper on SciHub.

[JohnJames]

With all due respect Clues, how do you know some of the improvements you are having are from removing mercury exposure from your dental amalgams?

Perfectly valid question JJ. I don't know for sure, it's just conjecture. There's more detail in my earlier posts in this thread, but basically I have symptoms that seems to match with mercury poisoning, and the chlorella immediately caused tingling and numbness in areas where I've had the most pain (jaw, lower back, feet), and over a few months it has alleviated some of my symptoms noticeably.

I'd welcome any tips on how to get myself tested.

Here is the full paper on SciHub.

The problem with this paper is that it doesn't state how the mercury dose was administered to the mice, and they began treatment immediately after exposure (Also the doses given to the mice seem VERY high). I would imagine if mercury was ingested by the mice, then the Chlorella may be particularly effective, since it does not get absorbed into the blood.

It takes a while after exposure for mercury to leave the bloodstream and into cells and organs (weeks for humans) and start causing damage, starting treatment immediately whilst mercury is still in the gut with binders may effectively prevent mercury from becoming intracellular and is excreted with the binder before that occurs. It does not show that Chlorella removes mercury from organs or from cells.

An example of this is below, note the timing of the symptoms appearing:
https://www.youtube.com/watch?v=NJ7M01jV058

In fact, the authors of the paper specifically address this in the discussion:

This indicates that
Chlorella effectively binds with mercury and facilitates
its excretion through faeces. As Chlorella does not absorb
through the gut, it excretes completely through the faeces.
The whole tissue retention of mercury was found to be
less, whereas elimination of mercury was high in
Chlorella-treated groups compared to control groups.
The sulphur-containing chelating agents DMPS and
DMSA have greater affinity for mercury and excrete
through the kidney by forming complex with mercury

Best test is to try chelating (I've covered tests on another post in this thread).

I think personal experience is important, and since it wasn't too long ago you removed your amalgams the Chlorella may be mopping up still floating around your gut from recent exposures.

[Clues]

JJ, thanks for your input.

The fillings I removed recently were in all likelihood not the biggest problem though. They were very small and stable, and were removed carefully. The ones I removed 10-ish years ago were much bigger, and one of them was noticeably worn down from chewing. Also, I've had my symptoms, including POIS, for at least 20 years. So if I do have a mercury issue, the mercury is probably everywhere by now.

I respect your skepticism about the efficacy of Chlorella, but it definitely feels like something is happening in my limbs and skin in particular, which I don't know how to explain unless something is being absorbed into my bloodstream and is affecting more than just my gut. I've read somewhere about detoxing mercury that the most readily-available mercury is removed first, and it feels like something like that is happening in my legs: When I first started taking Chlorella, my calves and feet were numb and tingly to the point where I stumbled while walking and had to reduce the dose. Then gradually, the tingling and numbness receded downwards, and now I only feel it in my feet, especially the bottom couple of inches from the ground.

One thing to note, I guess, is that I do take small amounts of cilantro with my food. I think I read somewhere (sorry, don't have a source) that garlic and a couple of other foods can also mobilise mercury, and I have been eating a fair bit of that as it helps the gut and helps against mast cell activity. So maybe those things are mobilising the mercury and the Chlorella is capturing it somehow? I don't know. But the net effect, whatever it is, is definitely positive so far, and as the risk seems low-to-nonexistent, I'll keep taking Chlorella for now.

I'll definitely consider chelating, but I'm hesitant to go there right now because 1. all the info I've found about ACC online seems anecdotal and I can't find any solid sources with even rudimentary research, 2. I'm on a very limited budget, and importing DMSA and buying the other supplements I'll need is a bit much considering I don't even know for sure if mercury is my problem. (Presumably I'd need mineral supplements? Or does DMSA only chelate the bad stuff?)

[JohnJames]

Little update from me: ejaculated twice yesterday. Only symptom I have this morning is a bit of tiredness, and that might be because I went to bed a little late.

JJ, thanks for your input.

The fillings I removed recently were in all likelihood not the biggest problem though. They were very small and stable, and were removed carefully. The ones I removed 10-ish years ago were much bigger, and one of them was noticeably worn down from chewing. Also, I've had my symptoms, including POIS, for at least 20 years. So if I do have a mercury issue, the mercury is probably everywhere by now.

I respect your skepticism about the efficacy of Chlorella, but it definitely feels like something is happening in my limbs and skin in particular, which I don't know how to explain unless something is being absorbed into my bloodstream and is affecting more than just my gut. I've read somewhere about detoxing mercury that the most readily-available mercury is removed first, and it feels like something like that is happening in my legs: When I first started taking Chlorella, my calves and feet were numb and tingly to the point where I stumbled while walking and had to reduce the dose. Then gradually, the tingling and numbness receded downwards, and now I only feel it in my feet, especially the bottom couple of inches from the ground.

One thing to note, I guess, is that I do take small amounts of cilantro with my food. I think I read somewhere (sorry, don't have a source) that garlic and a couple of other foods can also mobilise mercury, and I have been eating a fair bit of that as it helps the gut and helps against mast cell activity. So maybe those things are mobilising the mercury and the Chlorella is capturing it somehow? I don't know. But the net effect, whatever it is, is definitely positive so far, and as the risk seems low-to-nonexistent, I'll keep taking Chlorella for now.

I'll definitely consider chelating, but I'm hesitant to go there right now because 1. all the info I've found about ACC online seems anecdotal and I can't find any solid sources with even rudimentary research, 2. I'm on a very limited budget, and importing DMSA and buying the other supplements I'll need is a bit much considering I don't even know for sure if mercury is my problem. (Presumably I'd need mineral supplements? Or does DMSA only chelate the bad stuff?)

Amalgams of any kind constantly off-gas mercury which you breathe in and absorb through your lungs. There is enough mercury in even a small amalgam filling to kill you many times over. Swallowing solid chunks of amalgam isn't actually that bad and doesn't get absorbed.

As stated before, there is a huge abundance of scientific evidence on the use of ALA and DMSA as chelating agents for curing mercury poisoning, which Andy drew upon the create ACC. In fact, there is far far less evidence on the use of Chlorella/Cilantro to cure mercury poisoning.

you don't need mineral supplements, on ACC you only need the core 4. ACC is very cheap to do, especially if you buy ALA powder in bulk and make your own tablets, but even if you don't it's still pretty cheap.

The way I see it: the only downside to ACC is cost, the upside is there's a possibility it cures your POIS. You'll figure out within a couple of rounds if it's doing anything or not (probably even the first round). To me it seems like a no brainer.

[DEANNX]

Hi John, congrat on your progress, I remember your POIS last for two weeks, I wonder how many round it takes for your POIS duration to reduce by 1 day?

[DEANNX]

https://andy-cutler-chelation.com/mercury-detox-forums/viewtopic.php?f=2&t=277&hilit=selenium

just found a post about selenium and mercury on the mercury detox forum.

a guy said that selenium can redistribute mercury to somewhere it cant damage our health but doesnt chelate it.

[Igy78]

Hi again, little feedback after a while, finally found the root cause of my problems, the liver, (probably mercury in there). Accidently, girlfriend said give this a try and i tried, taking 2 pill in the morning and 2 pill before sleep. I also have diagnosed fatty liver. Liver has 500 functions.

https://www.dietpharm.com/en/proizvodi/silimarin-articoka-kapsule/

Contains:    The recommended daily dose 1 capsule    % NRV*
Dry standardized extract of milk thistle fruit (Silybum marianum)    175 mg    -
containing silymarin    140 mg
Dry artichoke leaf extract (Cynara scolymus) with at least of 2% cynarin    100 mg    -
Vitamin E (D-alpha-tocopherol)    15 mg α-TE    125
Zinc (zinc oxide)    7,5 mg    75
Selenium (sodium selenite)    25 μg    45


One function of liver is to filter cortisol trough the day. Cortisol is high in the morning to wake us up, and if liver is sick or fatty, liver can not filter cortisol from blood, and i got all jittery, angry, suicidal, aggressive and irritable. Constantly in fight or flight mode. Normal range of cortisol in the mornings are from 250-450, mine is 850. If i drink caffeine, symptoms get extra pumped.  All that symptoms are always high in the morning. And i got better and better trough the day because liver slowly filter cortisol. These pills are helping liver to filter whatever liver need to filter. From all things i tried these are helping the most. I hope i maybe helped somebody.

[BoneBroth]

A sluggish liver is certanly involved in the breakdown process from hormones (not only cortisol that is actually non-inflammatory). I always, 100% of time, get acne on my scalp and back on POIS and acne on the back is related to liver problems. The liver is also producing gall salts for fat metabolism and with a sluggish liver you will not absorb many B-vitamins properly - they are important for the whole hormonal balance. I've been taking supplements for the liver in periods after recommendations from therapists, but I don't experience much improvement from POIS. Maybe I should get on it again...