Post Orgasmic Illness Syndrome (P.O.I.S.)

POIS Cause/Treatment Discussions => General Alternative Causes and Treatments of POIS => Topic started by: Hopeoneday on January 27, 2020, 12:09:38 PM

Title: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Hopeoneday on January 27, 2020, 12:09:38 PM
Hi guys, as you all know that i(we all do some more some less) trying to figure out what is the real cause of  ours  illnes.
After 3 years of researching from this forum and 15 years back looking for the cause of my illness, I have looked at the whole thing and I think I can relate what is the cause of our illness.

Mercury intolerance))leaky gut)) Mercury retention)) Immunity compromised))
Prone to Lyme disease)) Impaired central nervous system)) Impaired vagus nerve(mercury disbturbed acethylcholine pathways) ))Chronic fatigue(mitohondria impacted))Syastemic inflamation))Parcinson lyke symptoms))Prone to autoimune illness))


In short: Mercury intolerance))leaky gut))Mercury retention))POIS

(Pois with lyme is the worst type of pois)
(other types of pois is lighter versions of pois).
Pois types you can found of forum under Quantum profile.


Cruciall links info:
What is the funniest thing to me about this is that
everything I was exploring was also
mentioned the summary in this slide.
Scroll and learn:

https://www.slideshare.net/keithberndtson/detoxification

Could Mercury Toxicity Be Causing Your Symptoms?
Important, read comments of peoples on the botom.
https://chriskresser.com/could-mercury-toxicity-be-causing-your-symptoms/


For years i search reason for my condition, and i try to find solution
folowing my symptomes, the first thing i discovered that my symptomes
lead me to lyme disies, than later fit with mercury toxicity symptoms,
then that lead me to discover pois forums, wich lead me to a lot of info
an pois types on forum, then i reasarched imunity theory,   then i leaded virus
dicusion on forum(some mans healed from antivirals on forum from my sugestion)
, then i discovered that some of us are imunocompromised(like neutrophenia),
then i dicovered that mercury can supress dispturb imunity, then i dicovered
that lyme can disbturb imunity, than i disovered that  mercury and lyme connection
, (bugs love hawy metals, they use it for protection from imunity
-biofilms).
I was shocked when i discower hundreds of web pages of mercury
and lyme connection , mercury can disbturb imune system and many many
factorses in ours body, and we are prone to meny chronic conditions,
then i discovered leaky gut and this leaky gut isues fitt perfectly
in mercury retention and reabsorbtion cycle in body, that keep us in
chronicly toxic and chronicly ill vicious cycle.
Genetic factors and bad luck play big role here.


The moment we begin to have sexual arousal,
the body begins to prepare for ejaculation,
begins to withdraw nutrients from all places in the body,
start a major neurohormonal exchange,
in the process mercury is extracted from the organs,
fats and tissues and begin to circulate,
then we get mercury intolerance reaction))
this proces disbturb every single normall
pathway in our body. In the moment of ejculation ,
this proces is exsesive , ve get systemic inflamation
and  pois hitted hard like a storm from that .



In this theory here, we can put all the discusions we had on forum.

Start from the vagus nerve, to the neurotoxic
(neuro-autoimmune reaction, as many of us think),
to the lyme disease, virus theory,
symptoms like parkinson's (some poisers have developed
parcinson unfortunately), activation of mast cells,
testosterone deficiency, hi prolacitn, immunodeficiency,
immunocompromised, leaky gut, bowel problems, systemic inflammation,
autism spectrum, ocd spectrum, anxiety spectrum,
 everything just name it ???
Chronic mercury retention and intolerance (heavy metals),
is capable of causing all this !!! No medical marker for this ??
:) Thats why POIS has no marker!!!


Guys, I think hypersensitivity to mercury due to constant reabsorption and
retention of mercury and heavy metals is the root cause of POIS.


We have an intolerance to mercury and cannot get rid of it
of our body and we are always in a vicious circle.


I think in our ccase, intolerance to mercury
(and other heavy metals, but mercury is
main reason) they block all normal processes in our bodies,
especially our central nervous system CNS.


Mercury hipersensitivity
https://melisa.org/mercury/


How To Get This Lethal Poison Out Of Your Body
https://www.huffpost.com/entry/mercury-how-to-get-this-l_b_469358




Mercury destroy gut leanings too,(vicious cycle again, leaky gut)


What did i noticed? I noticed that every single suplement who did
helped poisers, increse gluthatione or fight inflamation.

GLuthation is the main body detox pathway.


See here...toxicity of mercury  and his gut repair protocol and his pois
is better and better, he can O free of pois.
https://poiscenter.com/forums/index.php?topic=2894.msg31869;topicseen#msg31869
Not that easy unfortunatly for all of us, because all of us is afeceted
diferently(seee Quantum pois charts).



Look at here on a guy wich benefit from  methylation but not
100%, he did get cured 100% when he included this
https://poiscenter.com/forums/index.php?topic=2831.msg25781#msg25781

NAC              ( incriese gluthation)
Selenomethionine (incriese gluthation, chelate the mercury from the body "safe")
Taurine          (incriese gluthation)
Zink             (incriese gluthation , chelator, help on gut yunktions repair
,leaky gut repair).

And he taked probiotics for guts, and had stoped his pois in 100%!!!



Any supplement that successfully aids here in the forum,
increases gluthation or acts on inflammation and interferes
with mercury from oxidation and thus helps us.

Some people (us poisers) need 20 years to exterminate mercury
from the brain ...

Mercury has a very negative effect on immunity
(which is why we compromise immunity)
Immunocompromised people have various chronic infections:
Lyme disease, bowel infections (candida, bacteria like metals).

Due to this negative impact of mercury,
many autoimmune diseases are created in humans.

That is why we are susceptible to infections.

Mercury lowers neutrophils.

Mercury itself destroys the gut wall, this is where the paradox resurfaces,
Mercury and other toxins are reabsorbed into the blood and then re-absorbed
they go to the brain, organs and tissues.

Mercury causes a decrease in testosterone. (because mercury in the brain has
 a negative effect on the pituitary gland)

Mercury are deposited in thyroid gland, dispturb normall work of gland,
it can couse hiden type of thayroid isues and
autioimunity.
Iif you ask me thyroid thype of pois chart exist like meber SWELL!!!)

Mercury interferes with the action of the gabba.

Mercury interferes with the action of dopamine.

Why are some here "cured" by methylation?

Increasing methylation increases gluthathion.

Why Vitamin B Helps - Increases Gluthation.
Why Vitamin D Helps - Enhances Gluthation.
Why Vitamin C Helps - Enhances Gluthation.
Why Zinc Help - Increases Gluthation.
Why NAC Helps - Greatly Increases Gluthathion.


Mercury interferes with acetacholine processes
and therefore interferes with the functioning of the vagus nerve.

Mercury induces the activation of mast cells.

Mercury irritates the adrenal glands (mercury deposits in the kidneys and
irritates the adrenal glands)

Mercury prevents mitochondria from working properly (causes chronic fatigue)


A vicious cycle of mercury retention and redistribution,
because of leaky gut and disbturbed proceses of gluthation.

But in leaky gut, mercury do reabsorbing again
on blood and go in the brain and other tissues.

Mercury be deposited in meny organs ,
like kidnes and in prostate and testicles too.

Mercury shold be exited from body with detox fazes(main glutation) in feces,
mercury love fat, from that reason mercury go
to the brain an be deposited there too.

 

Wery good study for infoo about topic:

Connections and links:

Mercury Toxicity and Treatment
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253456/#!po=11.8750

mercury lyme connection.
https://drpompa.com/podcasts/143-back-to-life-after-lyme-and-mercury-poisoning/

So posible solution, if you asking me, i do not advice forced extration mercury and
hawy metals toxins from body, i advice naturall ways and naturall chelators.

1. Gut healing, leaky gut repair, this is the most important thing, and wery hard to repair
because we are in vicious cicle which from is wery hard to get out.
but we can se on our forum that some peoples are suscesifully repair theirs
guts and improved their healt and pois, some of them cured complitly.
With bad gut, leaky gut... mercury and odher toxins are allways reabsorbed back in
blod the redistributed in brain an all ower the body organs and tisiues again.

2.Get rid of your mercury sources and other toxins exposures.

3. After that follow some safe naturall mercury chelators protocols
First, clean mercury from body, after that use chilantro to clean
mercury from brain, because chorella cant cross BB barier.
It is wery imortant to use naturall binders like vitamince C and
aplle pectins powder etc....espheshaly for lyme poisers.
The same thing do NAC(chelate from body), ALA(chelate from brain)...
Title: Re: The root couse of POIS (under construction)
Post by: Hopeoneday on January 27, 2020, 12:39:29 PM
Under construction!
Title: Re: The root couse of POIS (under construction)
Post by: demografx on January 28, 2020, 01:23:30 AM
Thanks, HOD, looking forward to your POIS presentation!
Title: Re: The root couse of POIS (under construction)
Post by: Hopeoneday on February 01, 2020, 12:16:30 PM
Guys, i will update this post, put more links reffereces and explanations.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Hopeoneday on February 01, 2020, 05:30:14 PM
Adeed connections.
https://drpompa.com/podcasts/143-back-to-life-after-lyme-and-mercury-poisoning/

Mercury Leaky Gut and Mast Cell Histamine Release
https://www.mercurymadness.info/the-hidden-obstacle-to-your-recovery-from-mercury-poisoning-leaky-gut-and-mast-cell-histamine-release/

Cruciall links for info...
Could Mercury Toxicity Be Causing Your Symptoms?
Important, read comments of peoples on the botom.
https://chriskresser.com/could-mercury-toxicity-be-causing-your-symptoms/
Mercury 101: Three Forms of Mercury
Different Individuals, Different Rates of Mercury Detox
Mercury Detox Is Affected by Numerous Factors
Chronic Inflammation = Impaired Detoxification. And, Mercury = Chronic Inflammation. A Vicious Cycle.
Inflammation Makes Us More Susceptible to Mercury Toxicity
Mercury Affects Every Cell and System in Our Body
Our Nervous System Is Particularly Vulnerable to Mercury Toxicity
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Limejuice on February 01, 2020, 09:06:17 PM
I've tested positive for leaky gut, and negative for mercury and other heavy metals.  However, it's unclear what my root causes of leaky gut are... gluten and dairy are definitely one cause but suspect something else is an issue too.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Investigator on February 02, 2020, 07:26:38 AM
Thank you, HOD, for the extensive review. A Melisa test showed that I have a strong positive reaction (that is to say, hypersensitivity) to inorganic mercury. Here are some of my views on mercury:

1) One should distinguish between mercury toxicity (this is when mercury messes up the function of organs - possibly some gland, or the testicles, or the brain) and mercury hypersensitivity (allergy type IV). These are different things, with different symptoms. Interestingly, our symptoms include ones from both types.

2) If a test shows "mercury within normal range" -- this means absolutely nothing. It is well-established that for mercury, there is NO "safe range" for some people. In other words, an amount of mercury that can be tolerated by 99.9% of the population (and hence considered within lab range) may cause illness in the remaining 0.1%. It doesn't matter if you do a blood, urine, hair, or nails test (the latter two are most useful for chronic poisoning).   

3) A few more properties of mercury. Mercury is known to act as a vasoconstrictor on blood vessels. Many examples in this forum show that vasodilators (e.g. garlic or niacin) help for the symptoms. Also, people here report that they feel bad during wet and moist weather, and better during dry weather. Well, I've read about this one experiment in which they poison mice with mercury; one group is left in a dry place and the other in a wet place. The one in the wet place shows less mercury in a blood test (i.e., the mercury is absorbed more in the body), and the mice in the dry place live longer after being poisoned. So, moisture is bad for mercury toxicity. I've even read that people with mercury toxicity feel tired after a shower - this has been reported here in the forum as well. Lots of smoking gun.

4) Most importantly, to the point. There are tons of information on the internet, e.g. Andy Cutler chelation, other chelation protocols (e.g. http://www.toxaprevent.co.uk/ or Quicksilver Scientific, https://www.quicksilverscientific.com/) about how to chelate mercury. The problem is, each one says this is the only safe way, and all the others are bad and unsafe. I don't know which one to trust. I can't really find scientific articles in peer-reviewed journals that say: "this method was tested extensively and is considered safe." I am not convinced that chelation is a safe process, that's what I worry about. I don't know if these chelation protocols have been tested on lab animals - for example, for side effects. 

5) In any case, do not chelate until your amalgamas are out. Else, things may become worse. The literature is consistent on this.

But yes, I totally agree with you on the mercury toxicity/hypersensitivity hypothesis.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Hopeoneday on February 03, 2020, 07:21:55 AM
Yes, this as Investigator explaned...Limejuice.
This theory so far fits all types of POISs.
The Investigator sees the whole picture, he reads and relates things.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Investigator on February 03, 2020, 03:46:14 PM
What I miss however, is that it seems not everybody on this forum has had amalgam fillings. That's what makes me skeptical about this whole mercury toxicity/hypersensitivity hypothesis as a root cause for POIS. While it is true that there are other sources of mercury (like fish), I think the main one generally is amalgam fillings. It doesn't look like many people here have them (evidence: see that that mercury threads are not super active). There was an old poll about mercury, and several members have replied they've never had amalgamas.

So, thanks for the compliment, HOD, but the above paragraph is one piece I really am missing from this puzzle. I still believe in the mercury hypothesis, though, just trying to link this with everything else.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Mushnikk on February 03, 2020, 03:47:33 PM
I have never had amalgam fillings.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Investigator on February 03, 2020, 03:57:28 PM
There we go, here is precisely where the mercury theory breaks. Thanks for the answer, Mushnikk.

I also presume you haven't played with a broken thermometer when you were young or anything like that? And that POIS didn't start soon after a vaccine? Or you weren't eating loads of salmon over an extended period of time? If it's "none of the above," then the mercury theory has a serious gap that HOD and I have to address. 

Or it could be some other metal, like nickel. I also have hypersensitivity to nickel (though not as strong as to mercury), shown on a Melisa test. But this is more common, many people have allergy (type IV) to nickel. Do you have metal or metal-ceramics dental crowns, Mushnikk?

Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Hopeoneday on February 03, 2020, 04:21:35 PM
People don't want to read to understand, to connect things.
People want 3-4 pills and they can be cured immediately.
But unfortunately, in our case, it is not so easy, only the lucky ones.
No-amalgam fillings are nothing to this theory, people can be toxic
from old colors , just one example.
The essence of this theory is toxicity, the buildup of toxins due to leaky gut, and the emphasis is on the sensitivity to mercury,
ie the emphasis on the vicious circle, that we are always chronically toxic and that is why some of us have chronic infections.

I never expected this tread to be active, due to misunderstanding.
And so with lyme didease, for a year and a half, I say some of us have layme disies, but no one believes,
because they do not know that a negative chronic lyme test means nothing.
And suddenly in the last half year 5 poisers are diagnosed with lyme disease.
You don't have to have lyme disies with POIS!
But POIS is a herxheimer reaction,
we will know in the future what.
(one fine sunny day).


Mobilization, redistibution, retention due leaky gut and felure of detox fases,
gluthationa as main.

When I say here that lyme disease and mercury are related, people here will say wha ???
Write on google (lyme mercury)


Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Limejuice on February 03, 2020, 07:28:36 PM
As a child I had amalgam filings but those have long ago fallen out.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Investigator on February 04, 2020, 04:31:00 PM
Aha, now I see what HOD suggests: the root cause could be deficiency in detoxification, and so the symptoms appear due to accumulation of toxins. It could be different toxins for different people. For some it could be one thing, for others - another thing. Hence the different types of POIS.

It could be, who knows. I've heard about "total toxic load" - the idea that you start having some symptoms once toxins of various types accumulate beyond a certain threshold. But if it's like that, why are our symptoms so similar?
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: marrtintintin on February 05, 2020, 04:47:55 PM
People don't want to read to understand, to connect things.
People want 3-4 pills and they can be cured immediately.
But unfortunately, in our case, it is not so easy, only the lucky ones.
No-amalgam fillings are nothing to this theory, people can be toxic
from old colors , just one example.
The essence of this theory is toxicity, the buildup of toxins due to leaky gut, and the emphasis is on the sensitivity to mercury,
ie the emphasis on the vicious circle, that we are always chronically toxic and that is why some of us have chronic infections.

I never expected this tread to be active, due to misunderstanding.
And so with lyme didease, for a year and a half, I say some of us have layme disies, but no one believes,
because they do not know that a negative chronic lyme test means nothing.
And suddenly in the last half year 5 poisers are diagnosed with lyme disease.
You don't have to have lyme disies with POIS!
But POIS is a herxheimer reaction,
we will know in the future what.
(one fine sunny day).


Mobilization, redistibution, retention due leaky gut and felure of detox fases,
gluthationa as main.

When I say here that lyme disease and mercury are related, people here will say wha ???
Write on google (lyme mercury)

Hi man,

I like your emphasis on a natural/journey approach to POIS. (if i didn’t misunderstand you) What are you currently doing to cure your gut and enhance detox?

Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Muon on February 06, 2020, 06:19:32 PM
People want 3-4 pills and they can be cured immediately.
But unfortunately, in our case, it is not so easy, only the lucky ones.

I completely agree.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: JohnJames on February 15, 2020, 10:59:10 AM
Thank you, HOD, for the extensive review. A Melisa test showed that I have a strong positive reaction (that is to say, hypersensitivity) to inorganic mercury. Here are some of my views on mercury:

4) Most importantly, to the point. There are tons of information on the internet, e.g. Andy Cutler chelation, other chelation protocols (e.g. http://www.toxaprevent.co.uk/ or Quicksilver Scientific, https://www.quicksilverscientific.com/) about how to chelate mercury. The problem is, each one says this is the only safe way, and all the others are bad and unsafe. I don't know which one to trust. I can't really find scientific articles in peer-reviewed journals that say: "this method was tested extensively and is considered safe." I am not convinced that chelation is a safe process, that's what I worry about. I don't know if these chelation protocols have been tested on lab animals - for example, for side effects. 



Quicksilver is a known multilevel marketing scheme which uses binders which do NOT have the chemical properties required to chelate. As far as am I am aware all known chelators of mercury are dithiols (ALA, DMSA, DMPS).

I have followed ACC for over a year now and my POIS is significantly improved, and I believe I will be 100% cured in another year. Understand that ACC was developed by people testing things on a forum in the 90s through trial and error, Andy just happened to partake and happened to have the scientific knowledge to piece together why it works, Andy also applied the half-life dosing idea used throughout the medical industry.

There are no "tests" which can accurately show mercury burden, this is only possible through autopsy. Andy thought the best way to test for mercury would be just to try his protocol, and any sort of reaction to the chelators confirms mercury (positive or negative).

What I miss however, is that it seems not everybody on this forum has had amalgam fillings. That's what makes me skeptical about this whole mercury toxicity/hypersensitivity hypothesis as a root cause for POIS. While it is true that there are other sources of mercury (like fish), I think the main one generally is amalgam fillings. It doesn't look like many people here have them (evidence: see that that mercury threads are not super active). There was an old poll about mercury, and several members have replied they've never had amalgamas.

So, thanks for the compliment, HOD, but the above paragraph is one piece I really am missing from this puzzle. I still believe in the mercury hypothesis, though, just trying to link this with everything else.

It doesn't matter if you never had amalgams, mercury can be passed from parent to child. So if your mother had amalgams, or your grandmother then it's still possible. Also, their are other exposures to mercury:- broken CFL lamps, vaccines (this is controversial but it is a scientific fact that many contain thimerasol which is used as a preservative), bulbs.. many more. Their are many people on the ACC forums whom have never had amalgams who have found significant improvements/been cured from similar autoimmune conditions to POIS. Even a trip to a conventional dentist office exposes you.

Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: marrtintintin on February 15, 2020, 01:28:14 PM
Hi JohnJames, your post is quite promising!
Could you clarify what does “following ACC” means, please.
And secondly, as your POIS symptoms have improved, has your digestion improved (if you had leaky gut, or any digestion problem)?
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: cn7 on February 15, 2020, 03:26:49 PM
Sorry but this is just pseudo science, dont go that way. I cant tell you how many times i thought i had found the root of my problems.

Lyme. Histamine intolerance. Leaky gut. Adrenal fatigue. You can go that way for years and you'll end up nowhere.

But in the end it doesnt work because its bullshit
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: demografx on February 15, 2020, 03:35:56 PM
cn7, many of us understand your frustration. But please don’t give up. Personally, I’m just hoping for some useful POIS-antidote info - not necessarily an all-conquering cure -  that will come out of all this hypothetical searching. Something more than we had, say, one year ago.

Scientific progress is slow. Even for well-funded syndromes, e.g., CFS (chronic fatigue syndrome). Million$ spent, but very little progress.

I’ve been with the forum since 2007
(POIS’ Dark Ages :) ) and the progress I’ve seen has been impressive. Even with zero funding, this forum has advanced its thinking greatly in its attack on the POIS problem! If only 10% of what we find is ultimately useful (90% “useless”)...we’re still way ahead of the game.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: JohnJames on February 16, 2020, 05:51:10 AM
Hi JohnJames, your post is quite promising!
Could you clarify what does “following ACC” means, please.
And secondly, as your POIS symptoms have improved, has your digestion improved (if you had leaky gut, or any digestion problem)?

ACC = Andy Cutler Chelation, it's just a safe way to remove mercury from the body/brain based on the research into treating acute mercury poisoning.

Yes, the following has all improved gradually for me over the last year: insomnia, brain fog, tiredness/fatigue, digestion, social aptitude, depression, the feeling that you feel sort of numb and dead inside, dandruff, skin problems. I'm free to orgasm over the weekends if I please, the day after can be a little rough but it no longer takes me out for a week.

Most people with mercury issues tend to have gut problems.

Sorry but this is just pseudo science, dont go that way. I cant tell you how many times i thought i had found the root of my problems.

Lyme. Histamine intolerance. Leaky gut. Adrenal fatigue. You can go that way for years and you'll end up nowhere.

But in the end it doesnt work because its bullshit

I disagree. I don't think this is a genetic problem - it doesn't make evolutionary sense that some people are just ill and that's all there is to it. Which means it's likely to be something we have done or do in our modern lifestyle that wouldn't of been a problem for us during our evolutionary history. For example, grains are relatively new to the human diet, and it seems alot of people run into issues when they incorporate grains. Similarly, many medications, surgeries, environmental exposures, etc... are all relatively new, we haven't done studies over generations for many of the things we are exposed to and are generally considered safe.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Mushnikk on February 16, 2020, 07:16:53 AM
Hi JohnJames, your post is quite promising!
Could you clarify what does “following ACC” means, please.
And secondly, as your POIS symptoms have improved, has your digestion improved (if you had leaky gut, or any digestion problem)?

ACC = Andy Cutler Chelation, it's just a safe way to remove mercury from the body/brain based on the research into treating acute mercury poisoning.

Yes, the following has all improved gradually for me over the last year: insomnia, brain fog, tiredness/fatigue, digestion, social aptitude, depression, the feeling that you feel sort of numb and dead inside, dandruff, skin problems. I'm free to orgasm over the weekends if I please, the day after can be a little rough but it no longer takes me out for a week.

Most people with mercury issues tend to have gut problems.

Sorry but this is just pseudo science, dont go that way. I cant tell you how many times i thought i had found the root of my problems.

Lyme. Histamine intolerance. Leaky gut. Adrenal fatigue. You can go that way for years and you'll end up nowhere.

But in the end it doesnt work because its bullshit

I disagree. I don't think this is a genetic problem - it doesn't make evolutionary sense that some people are just ill and that's all there is to it. Which means it's likely to be something we have done or do in our modern lifestyle that wouldn't of been a problem for us during our evolutionary history. For example, grains are relatively new to the human diet, and it seems alot of people run into issues when they incorporate grains. Similarly, many medications, surgeries, environmental exposures, etc... are all relatively new, we haven't done studies over generations for many of the things we are exposed to and are generally considered safe.

Would you be so kind to share what ressource you used to do the particular chelation for something who wants to read up on it.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: JohnJames on February 16, 2020, 07:38:13 AM
Hi JohnJames, your post is quite promising!
Could you clarify what does “following ACC” means, please.
And secondly, as your POIS symptoms have improved, has your digestion improved (if you had leaky gut, or any digestion problem)?

ACC = Andy Cutler Chelation, it's just a safe way to remove mercury from the body/brain based on the research into treating acute mercury poisoning.

Yes, the following has all improved gradually for me over the last year: insomnia, brain fog, tiredness/fatigue, digestion, social aptitude, depression, the feeling that you feel sort of numb and dead inside, dandruff, skin problems. I'm free to orgasm over the weekends if I please, the day after can be a little rough but it no longer takes me out for a week.

Most people with mercury issues tend to have gut problems.

Sorry but this is just pseudo science, dont go that way. I cant tell you how many times i thought i had found the root of my problems.

Lyme. Histamine intolerance. Leaky gut. Adrenal fatigue. You can go that way for years and you'll end up nowhere.

But in the end it doesnt work because its bullshit

I disagree. I don't think this is a genetic problem - it doesn't make evolutionary sense that some people are just ill and that's all there is to it. Which means it's likely to be something we have done or do in our modern lifestyle that wouldn't of been a problem for us during our evolutionary history. For example, grains are relatively new to the human diet, and it seems alot of people run into issues when they incorporate grains. Similarly, many medications, surgeries, environmental exposures, etc... are all relatively new, we haven't done studies over generations for many of the things we are exposed to and are generally considered safe.

Would you be so kind to share what ressource you used to do the particular chelation for something who wants to read up on it.

Sure,

Andy has a book called "Amalgam Illness" which talks alot about the protocol and how it all works etc and the damage mercury causes and how it does it, there are some free pages on google books: https://books.google.co.uk/books/about/Amalgam_Illness.html?id=ZG9glNfif5YC&redir_esc=v

(apologies if this is against the rules I'm not advertising and don't stand to make any financial gain from this).

However, there are a number of places to read about how to chelate using ACC, you don't need the book to do the method but it is an interesting read nevertheless, apologies about some of the sites they aren't the prettiest:
https://thepowerofozone.com/chelate-andrew-cutler-protocol/
https://andy-cutler-chelation.com
https://nataliehanson.com/2018/02/04/acc-protocol/
https://www.westonaprice.org/health-topics/environmental-toxins/using-the-andy-cutler-protocol-to-address-mercury-poisoning/
https://www.livingnetwork.co.za/chelationnetwork/chelation-the-andy-cutler-protocol/

The facebook group is probably the best place, there are 60000 members, many of whom are chelating or have found success with chelation and are willing to help others start, including a number of volunteer dentists who can check to make sure your amalgams were properly removed (very very important!).

Also the following link is super helpful and I think helps illustrate the sort of character Andy was before passing:
http://onibasu.com/wiki/Cutler_protocol.html

Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Investigator on February 16, 2020, 12:56:18 PM
JohnJames, please keep us updated on how the chelation is going, your experience is really important to share. My dental situation is so complicated that it will take another at least half year until I clean my mouth from the amalgamas (they are under crowns). Then I will be ready for ACC. 
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: marrtintintin on February 18, 2020, 08:54:58 AM
Thank you! @johnjames

Is mercury poising something that I can get a test? Like a blood test?

Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: marrtintintin on February 18, 2020, 09:22:59 AM
Sorry but this is just pseudo science, dont go that way. I cant tell you how many times i thought i had found the root of my problems.

Lyme. Histamine intolerance. Leaky gut. Adrenal fatigue. You can go that way for years and you'll end up nowhere.

But in the end it doesnt work because its bullshit

Hi, thanks cn7 for keeping me down to earth and demografx for your persistence—two essential qualities.
 I wouldn’t want to discard anything just because it’s “pseudoscience”. In this kind of illness, laypersons’ knowledge is fundamental. And this is what

The contribution of laypersons to science is something that works, especially for rare illnesses. It is very well explained in Michael Callon’s book: acting in an uncertain world.
If you start reading the book, you’ll notice that This forum is very very similar to the French Muscular Dystrophy Association (AFM) cited in the book—not bcs of the illness, but because of our common situation as a rare illness which has not yet been mapped out by the “scientific” community. In these situations, laypersons who are affected by the disease are essential for mapping out the causes of the illness—together with experts. The AFM has had huge succés for mapping out the different types of Muscular dystrophy and generating research and treatment.
Experts alone are of little use. They tend to treat cases like this one as isolated and provide quick fixes which do not solve the problem, e.g. the patient lacks testosterone, therefore we need to increase the patient’s testosterone. Instead, the question is, why does the patient lack testosterone?
In this COMMUNITY we are generating first-hand information from POIS affected ppl; plus there are very engaged laypersons in here who have gained a lot of expertise and try to collect the dots; and ultimately, we are reaching out to the scientific community. It’s the perfect cycle.

However, we might need more VISIBILITY as a group, so that more (unidentidied) POIS ppl can identify it; and hence get more support. In the case of the AFM they organise a parade every year to generate visibility and get funding. https://www.telethon7.com/telethon-weekend/

Callon’s book is a very good read, you can look at the summary here: https://books.google.es/books/about/Acting_in_an_Uncertain_World.html?id=i_bwmgEACAAJ&source=kp_book_description&redir_esc=y
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: marrtintintin on February 18, 2020, 09:26:38 AM
In this case, JohnJames has suggested that mercury intoxication might be at the root of the problem and has relieved some symptoms already.
The mercury hypotheses would make so much sense to me: because my mum has had lots of fillings and issues with her sexual organs (ovary) as well; also, my sister’s left breast didn’t develop, and my little brother was born with a cardiopathy.
So, this is no coincidence. Also, my mum has got a very explosive character, has lots of anger and anxiety, which is similar to POIS symptoms.
Now, The question for me is how do I know if I have mercury poisoning, is there any way to test this?
-Which of the testing methods did you do JohnJames?
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Investigator on February 18, 2020, 05:13:09 PM
Marrtintintin, the controversy is that there is no way really to test for mercury. Blood and urine tests are meant for acute mercury poisoning and show mercury that got into the body just recently (these are for people working in a factory, for example, if something wrong happens). Don't do these, they are not useful - they will surely show low levels. The standard is to use a hair test (or a nails test). However, they say (and this makes sense, but is not scientifically proven) that it is possible that the hair test shows mercury within normal range, while actually you have lots of mercury in the body (inside organs), just not so much in the hair. Others also say that even if the hair test shows a low level, for some people there is no "safe zone," so some people may get mercury mess up their organs even within what the lab may refer to as "safe limits." There is also a possibility for mercury allergy (which I have for sure), different from mercury poisoning. These make sense. Mercury is not good, one way or the other. 
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: JohnJames on February 19, 2020, 06:08:55 PM
In this case, JohnJames has suggested that mercury intoxication might be at the root of the problem and has relieved some symptoms already.
The mercury hypotheses would make so much sense to me: because my mum has had lots of fillings and issues with her sexual organs (ovary) as well; also, my sister’s left breast didn’t develop, and my little brother was born with a cardiopathy.
So, this is no coincidence. Also, my mum has got a very explosive character, has lots of anger and anxiety, which is similar to POIS symptoms.
Now, The question for me is how do I know if I have mercury poisoning, is there any way to test this?
-Which of the testing methods did you do JohnJames?

I'm sorry to hear that, my mother also had amalgams, as did my grandmother, and both of them suffer from mental health issues. Also there is a correlation between Restless Legs Syndrome and presence of dental amalgam in elderly people in the scientific literature, me, my grandmother, and my mother all have RLS.

There are no real test methods, your best bet is to just try the protocol with a low dose (please read up on it before you start and absolutely make sure you have no amalgam in your mouth, ask questions on the ACC forum they are all very useful). However, given your issues and background I would guess that it is likely that mercury is an issue for you.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Muon on February 19, 2020, 06:27:14 PM
I'm sorry to hear that, my mother also had amalgams, as did my grandmother, and both of them suffer from mental health issues. Also there is a correlation between Restless Legs Syndrome and presence of dental amalgam in elderly people in the scientific literature, me, my grandmother, and my mother all have RLS.

Table 4 Mercury (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003574/)

Restless legs syndrome is associated with mast cell activation syndrome (https://jcsm.aasm.org/doi/abs/10.5664/jcsm.8216)
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Investigator on February 20, 2020, 05:36:20 AM
Muon, under a hypothesis that mast cell activation is triggered by mercury, do you think getting rid of the mercury would also stop the mast cell activation?
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Muon on February 20, 2020, 09:38:22 AM
Muon, under a hypothesis that mast cell activation is triggered by mercury, do you think getting rid of the mercury would also stop the mast cell activation?
Depends on whether this is a major trigger. It's theoretically possible mast cell activation tones down when removing this trigger. It's a potential trigger but the question is whether this is a major trigger of mast cell activation in yourself. You could remove fillings and still end up in the same state. There is no way to tell. And keep in mind that this is different from toxicity.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Investigator on February 20, 2020, 02:44:57 PM
Thanks. What an immunologist explained to me once was that a combination of mercury and other things can make you allergic/hypersensitive to one of the other things that it interacts with, and then even without the mercury, the allergy stays, as your immune system remembers the irritation it received once.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: demografx on February 20, 2020, 06:13:45 PM
Investigator, please see my PM
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: JohnJames on February 21, 2020, 12:00:46 PM
On the ACC forums Mast Cell Activation syndrome is extremely extremely common and seems to disappear with chelation.

I'm sorry to hear that, my mother also had amalgams, as did my grandmother, and both of them suffer from mental health issues. Also there is a correlation between Restless Legs Syndrome and presence of dental amalgam in elderly people in the scientific literature, me, my grandmother, and my mother all have RLS.

Table 4 Mercury (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003574/)

Restless legs syndrome is associated with mast cell activation syndrome (https://jcsm.aasm.org/doi/abs/10.5664/jcsm.8216)

Interesting, this is what I was referring to if you wanted to take a look: https://www.sciencedirect.com/science/article/abs/pii/S1389945713018984
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Hopeoneday on February 28, 2020, 10:35:58 AM
Thanks JohnaJames for contributing, you understend the mater wery well.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Hopeoneday on February 28, 2020, 10:56:05 AM

This isnt a pseudoscience, this is all pure science studies.

Natural Phytotherapeutic Antioxidants in the Treatment of Mercury Intoxication-A Review
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156483/

Under findings.
As you can see, mercury is highly imunotoxic.


I noticed in poisers(including me) elevated bleedeng oral mucosa in pois.

Inflammation findings: Inflammation caused by the influence of heavy inorganic mercury causes the tendency to bleed in gingiva and oral mucosa. It increases the salivary secretion, causing sensation of metallic taste in the mouth. Gingiva, a gray line is formed, especially when the oral hygiene is bad.29

Endocrine findings: Thyroid function tests (TFTs) are thought to change levels. (Free-T3 and Free-T4). The most affected hormones by mercury are insulin, estrogen, testosterone and adrenaline.40-43


Neurological system findings: In humans, adverse neurological effects have been reported following high concentration acute mercury vapor inhalation. Generally, perceptual, personal, conceptual, and motor confusion are reported. The most important symptoms are tremor, emotional tenderness, insomnia, memory loss, neuromuscular changes (weakness, muscle atrophy and muscle withdrawal), headache and polyneuropathy.23,31-35 Exposure to mercury compounds at an early stage causes long-lasting and permanent neurobehavioral and neurochemical irregularities. Like Parkinson's disease and Alzheimer's disease.36

The elimination of mercury from the body is very difficult...

And meny meny more in thils link...

Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Hopeoneday on February 28, 2020, 11:05:05 AM
The pseudoscience:
Mercury is considered by WHO as one of the top ten chemicals or groups of chemicals of major public health concern. .
https://www.who.int/news-room/fact-sheets/detail/mercury-and-health

Mercury is contained in many products, including:

    batteries
    measuring devices, such as thermometers and barometers
    electric switches and relays in equipment
    lamps (including some types of light bulbs)
    dental amalgam (for dental fillings)
    skin-lightening products and other cosmetics
    pharmaceuticals.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Iwillbeatthis on February 28, 2020, 11:29:42 AM
Try liposomal glutathione there are many studies which show the chronically ill or even people with autism have very low glutathione stores. So supplementing with NAC isn't good I've tried NAC and liposomal glutathione is a million times better than that is supposed to have 1000x more glutathione than NAC

https://thesupermandiet.com/glutathione/ - good info and read
https://www.ncbi.nlm.nih.gov/pubmed/28853742

https://www.ncbi.nlm.nih.gov/pubmed/22781167
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Hopeoneday on February 28, 2020, 12:43:54 PM
Thanks Iwillbeatthis , eny usefull info is gold for us.
Keep reporting.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Hopeoneday on February 28, 2020, 03:13:12 PM
https://coremedscience.com/blogs/wellness/14-ways-liposomal-glutathione-can-boost-health

Connections ;)
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: JohnJames on February 28, 2020, 06:43:25 PM
Try liposomal glutathione there are many studies which show the chronically ill or even people with autism have very low glutathione stores. So supplementing with NAC isn't good I've tried NAC and liposomal glutathione is a million times better than that is supposed to have 1000x more glutathione than NAC

https://thesupermandiet.com/glutathione/ - good info and read
https://www.ncbi.nlm.nih.gov/pubmed/28853742

https://www.ncbi.nlm.nih.gov/pubmed/22781167

The mercury toxic tend to have low glutathione levels.

Andy said that glutathione should be avoided for the mercury toxic people as it would make them worse over time and seems to be corroborated with what people have experienced, but one could experiment with using NAC.

I can't fully remember the reasons why but I think Andy argued something like extracellular glutathione would redistribute mercury, whereas supporting your bodies own production of glutathione means the glutathione is created in the cell and pulls the mercury out but I'm not going to pretend I understand the biochemistry behind it all.

Thanks JohnaJames for contributing, you understend the mater wery well.

Thank you, people sharing what worked for them and what didn't has helped me so much and has been so valuable I want to pass on my own experience with dealing with this.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Muon on March 07, 2020, 06:30:47 AM
Peri-Implant Diseases and Host Inflammatory Response Involving Mast Cells: A Review (https://journals.sagepub.com/doi/pdf/10.1177/039463201102400302)
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Disaster on March 09, 2020, 07:36:06 PM
I see this type of correlation made all the time especially in ?syndrome? groups. It is sad because patients are so desperate for answers that they make correlation that do not imply causation. Meaning their desperation has caused them to grab fro answers that seem like they match which actually have no basis in evidence at all. Most of the time they reach for ?alternative? ?Pseudoscience? and they make big stretches of the imagination to connect the illness and the cures. A lot of logical critical thinking is bypassed. Sometimes they figure out they have these obscure other illnesses that can?t really be properly tested for like chronic Lyme disease, Mast Cell Activation, metal poisoning, and many more. And then the scam artists pick up on this and they start labs to test for these things and it?s big business. And you also see companies offering cures like Low Dose Naltrexone or supplements that can basically cure everything. It?s all sad to see, but I think we will see less of it the more research we get into POIS. Hopefully this new study sheds a lot of light and sparks more interest in the medical community.

As for Mercury sensitivity I?m not saying it?s impossible that it is the cause, I?m saying if it was it would be very random. In the last year I have been very interested in getting my mercury levels tested because my teeth are crumbling and the mercury is falling out of my mouth. I am probably digesting most of it. I have had POIS since my first orgasm so I probably had my first mercury fillings around that time so you could see a time relation there. But I think that correlation does not imply causation. A lot of things happened around that time and I could go down the list and just say that for everything. Also Mercury poisoning or sensitivity symptoms are all over the place and could be similar to a number of illnesses. That doesn?t really point to answers. Looks like blood levels and hair are good for Organic mercury and inorganic is better tested with 24 hour urine. I?m not really sold on a mercury sensitivity sounds like a grey area invented illness for profit.

As far as the study posted from Pubmed you have to investigate where those come from. Just because it is on pubmed does not mean it is scientific. That study was not a medical paper it was done in some obscure Turkish institute not a medical college, that has only been founded in 2007. I have no problem with theories as long as you explore them with some doubt not like you discovered a cure. According to MELISA they basically feel mercury sensitivity affects millions of people. If that was the case then millions of guys would have POIS, so right away that points to the theory being very wrong. Why is POIS so rare. By rare I mean less than a million people globally. It has to be something rare that is causing it Nd if mercury poisoning or sensitivity was so common and causing everything from Multiple Sclerosis to Autoimmune disease then POIS would have over 200,000 patients. It just does not make logical sense even though correlation makes it appear to match. I could make that with many illnesses like many have over the years on the forum. But you should think about this. Why doesn?t more men have it? Don?t just guess at the reason. Why are we more sensitive during orgasm. Are we having more mercury released during orgasm? Okay prove it. Otherwise I could claim anything is getting released and are sensitive to it. Doesn?t help and doesn?t point to it being correct.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: JohnJames on March 10, 2020, 02:25:34 PM
I see this type of correlation made all the time especially in ?syndrome? groups. It is sad because patients are so desperate for answers that they make correlation that do not imply causation. Meaning their desperation has caused them to grab fro answers that seem like they match which actually have no basis in evidence at all. Most of the time they reach for ?alternative? ?Pseudoscience? and they make big stretches of the imagination to connect the illness and the cures. A lot of logical critical thinking is bypassed. Sometimes they figure out they have these obscure other illnesses that can?t really be properly tested for like chronic Lyme disease, Mast Cell Activation, metal poisoning, and many more. And then the scam artists pick up on this and they start labs to test for these things and it?s big business. And you also see companies offering cures like Low Dose Naltrexone or supplements that can basically cure everything. It?s all sad to see, but I think we will see less of it the more research we get into POIS. Hopefully this new study sheds a lot of light and sparks more interest in the medical community.

As for Mercury sensitivity I?m not saying it?s impossible that it is the cause, I?m saying if it was it would be very random. In the last year I have been very interested in getting my mercury levels tested because my teeth are crumbling and the mercury is falling out of my mouth. I am probably digesting most of it. I have had POIS since my first orgasm so I probably had my first mercury fillings around that time so you could see a time relation there. But I think that correlation does not imply causation. A lot of things happened around that time and I could go down the list and just say that for everything. Also Mercury poisoning or sensitivity symptoms are all over the place and could be similar to a number of illnesses. That doesn?t really point to answers. Looks like blood levels and hair are good for Organic mercury and inorganic is better tested with 24 hour urine. I?m not really sold on a mercury sensitivity sounds like a grey area invented illness for profit.

As far as the study posted from Pubmed you have to investigate where those come from. Just because it is on pubmed does not mean it is scientific. That study was not a medical paper it was done in some obscure Turkish institute not a medical college, that has only been founded in 2007. I have no problem with theories as long as you explore them with some doubt not like you discovered a cure. According to MELISA they basically feel mercury sensitivity affects millions of people. If that was the case then millions of guys would have POIS, so right away that points to the theory being very wrong. Why is POIS so rare. By rare I mean less than a million people globally. It has to be something rare that is causing it Nd if mercury poisoning or sensitivity was so common and causing everything from Multiple Sclerosis to Autoimmune disease then POIS would have over 200,000 patients. It just does not make logical sense even though correlation makes it appear to match. I could make that with many illnesses like many have over the years on the forum. But you should think about this. Why doesn?t more men have it? Don?t just guess at the reason. Why are we more sensitive during orgasm. Are we having more mercury released during orgasm? Okay prove it. Otherwise I could claim anything is getting released and are sensitive to it. Doesn?t help and doesn?t point to it being correct.

I know that removing my amalgam and following the ACC has reduced the severity of my POIS symptoms, and that of another user. I know that there are 60'000 people on ACC forums many of whom are report improvements and or have been almost completely cured following ACC for seemingly related illnesses. I know it's not a scientific study, but there is certainly a cause and effect that is reasonably beyond placebo.

Andy is unfortunately no longer with us and does not gain monetarily and there are no companies advertising ACC, nor is it particularly costly.

Doesn't have to be rare, there are probably many more people with POIS not on this forum, and the number of people with related illnesses (CFS, depression etc) are not uncommon. Even the British Dental Association maintains that around 2% of patients are sensitive to mercury, so it is in the public scientific eye to some extent. There does also seem to be a sliding scale with illness such like POIS which would be explained by severity of mercury toxicity/sensitivity.

I don't think Mercury is released when you orgasm, as discussed in other areas of this forum, I think it's more likely existing mercury damages the many systems (hormonal, nervous system, ...) that means that the post-orgasm cascade results in our symptoms.

I'm too young to wait for this to be researched, I want to live my life now, not wait 30 years until they maybe find a cure, and my symptoms have improved a fair amount following ACC . For a healthy person, the only downside or "side-effect" to following ACC is the cost and time of getting your amalgams removed, and buying the ALA needed which is fairly inexpensive, but a healthy person should tolerate ALA with little to no side effects. There is no reason for me not to follow it since I have plenty of money/time.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Igy78 on March 16, 2020, 03:18:55 PM
Anyone wonders how our bodies will react with Corona virus, i mean mercury toxic people, i did recover from flu 3 months a go. I hope my immunity system will not go down or something.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: drop247 on March 18, 2020, 12:14:32 AM
Is Betain hcl + pepsin still helping your POIS Igy?
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Igy78 on March 18, 2020, 06:43:08 PM
Yes! i tested few days without pills, and pois symptoms slowly coming back, so i eat 15 pills before meal, eating one meal a day. In my case it was sleep apnea, which lead to lack of oxygen, lack of oxygen got me into fatty liver,  (google sleep apnea - liver, first video) fatty liver could not make gluthathion to remove mercury, mercury builds up over the years and ta daaaa, pois, low stomach acid, bacteria builds up in stomach and gut, suicidal thoughts after fapping and sex, chronic fatigue and so on.

What is really helping me was coffee enema, not doing regularly like before because i'm getting better, cpap device for eliminating sleep apnea, then origano oil and Grapefruit seed extract (GSE), origano oil, betain and GSE was life changer, i get 80-90% less symptoms, probably aiding liver in some way, i tried TON of vitamins/minerals and nothing helped like those 3. I'm on keto diet with here and there carbs one or twice a week.  Trying to heal my fatty liver now with those 3 suplement, i did abdomen scan and doctor told me my liver is enlarged and fatty. Fucking sleep apnea. Recently started to test fap and sex and symptoms was tolerable.

Good luck!
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: dylanmurphy on June 27, 2020, 03:09:41 PM
Hi JohnJames,

The mercury makes alot of sense, seeing as it most likely causes mcas and histamine intolerance.

How is all of your POIS symptoms now and other health issues since your last activity on this post in February??

Also how many rounds  of ACC have you done so far?
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: demografx on June 27, 2020, 09:10:56 PM
dylanmurphy, welcome to the forum.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: DEANNX on June 29, 2020, 01:33:38 AM
Interesting pose, but how is orgasm causing symptoms?
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: DEANNX on June 29, 2020, 02:28:26 AM
Thank you, HOD, for the extensive review. A Melisa test showed that I have a strong positive reaction (that is to say, hypersensitivity) to inorganic mercury. Here are some of my views on mercury:

4) Most importantly, to the point. There are tons of information on the internet, e.g. Andy Cutler chelation, other chelation protocols (e.g. http://www.toxaprevent.co.uk/ or Quicksilver Scientific, https://www.quicksilverscientific.com/) about how to chelate mercury. The problem is, each one says this is the only safe way, and all the others are bad and unsafe. I don't know which one to trust. I can't really find scientific articles in peer-reviewed journals that say: "this method was tested extensively and is considered safe." I am not convinced that chelation is a safe process, that's what I worry about. I don't know if these chelation protocols have been tested on lab animals - for example, for side effects. 



Quicksilver is a known multilevel marketing scheme which uses binders which do NOT have the chemical properties required to chelate. As far as am I am aware all known chelators of mercury are dithiols (ALA, DMSA, DMPS).

I have followed ACC for over a year now and my POIS is significantly improved, and I believe I will be 100% cured in another year. Understand that ACC was developed by people testing things on a forum in the 90s through trial and error, Andy just happened to partake and happened to have the scientific knowledge to piece together why it works, Andy also applied the half-life dosing idea used throughout the medical industry.

There are no "tests" which can accurately show mercury burden, this is only possible through autopsy. Andy thought the best way to test for mercury would be just to try his protocol, and any sort of reaction to the chelators confirms mercury (positive or negative).

What I miss however, is that it seems not everybody on this forum has had amalgam fillings. That's what makes me skeptical about this whole mercury toxicity/hypersensitivity hypothesis as a root cause for POIS. While it is true that there are other sources of mercury (like fish), I think the main one generally is amalgam fillings. It doesn't look like many people here have them (evidence: see that that mercury threads are not super active). There was an old poll about mercury, and several members have replied they've never had amalgamas.

So, thanks for the compliment, HOD, but the above paragraph is one piece I really am missing from this puzzle. I still believe in the mercury hypothesis, though, just trying to link this with everything else.

It doesn't matter if you never had amalgams, mercury can be passed from parent to child. So if your mother had amalgams, or your grandmother then it's still possible. Also, their are other exposures to mercury:- broken CFL lamps, vaccines (this is controversial but it is a scientific fact that many contain thimerasol which is used as a preservative), bulbs.. many more. Their are many people on the ACC forums whom have never had amalgams who have found significant improvements/been cured from similar autoimmune conditions to POIS. Even a trip to a conventional dentist office exposes you.
Hi John

I read that you have to take the supplements every 3 hours, did you do this everyday for one year or did you take break?

Thanks
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: IronFeather on July 13, 2020, 02:14:11 PM
There we go, here is precisely where the mercury theory breaks. Thanks for the answer, Mushnikk.

I also presume you haven't played with a broken thermometer when you were young or anything like that? And that POIS didn't start soon after a vaccine? Or you weren't eating loads of salmon over an extended period of time? If it's "none of the above," then the mercury theory has a serious gap that HOD and I have to address. 

Or it could be some other metal, like nickel. I also have hypersensitivity to nickel (though not as strong as to mercury), shown on a Melisa test. But this is more common, many people have allergy (type IV) to nickel. Do you have metal or metal-ceramics dental crowns, Mushnikk?

I'm not the person you were talking to, but this is very interesting. I have played with a thermometer as a kid, and broke it in half above my face. I had to have my eyes washed at the ER. Wow, you could be onto something...
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: JohnJames on July 14, 2020, 07:23:27 AM
Thank you, HOD, for the extensive review. A Melisa test showed that I have a strong positive reaction (that is to say, hypersensitivity) to inorganic mercury. Here are some of my views on mercury:

4) Most importantly, to the point. There are tons of information on the internet, e.g. Andy Cutler chelation, other chelation protocols (e.g. http://www.toxaprevent.co.uk/ or Quicksilver Scientific, https://www.quicksilverscientific.com/) about how to chelate mercury. The problem is, each one says this is the only safe way, and all the others are bad and unsafe. I don't know which one to trust. I can't really find scientific articles in peer-reviewed journals that say: "this method was tested extensively and is considered safe." I am not convinced that chelation is a safe process, that's what I worry about. I don't know if these chelation protocols have been tested on lab animals - for example, for side effects. 



Quicksilver is a known multilevel marketing scheme which uses binders which do NOT have the chemical properties required to chelate. As far as am I am aware all known chelators of mercury are dithiols (ALA, DMSA, DMPS).

I have followed ACC for over a year now and my POIS is significantly improved, and I believe I will be 100% cured in another year. Understand that ACC was developed by people testing things on a forum in the 90s through trial and error, Andy just happened to partake and happened to have the scientific knowledge to piece together why it works, Andy also applied the half-life dosing idea used throughout the medical industry.

There are no "tests" which can accurately show mercury burden, this is only possible through autopsy. Andy thought the best way to test for mercury would be just to try his protocol, and any sort of reaction to the chelators confirms mercury (positive or negative).

What I miss however, is that it seems not everybody on this forum has had amalgam fillings. That's what makes me skeptical about this whole mercury toxicity/hypersensitivity hypothesis as a root cause for POIS. While it is true that there are other sources of mercury (like fish), I think the main one generally is amalgam fillings. It doesn't look like many people here have them (evidence: see that that mercury threads are not super active). There was an old poll about mercury, and several members have replied they've never had amalgamas.

So, thanks for the compliment, HOD, but the above paragraph is one piece I really am missing from this puzzle. I still believe in the mercury hypothesis, though, just trying to link this with everything else.

It doesn't matter if you never had amalgams, mercury can be passed from parent to child. So if your mother had amalgams, or your grandmother then it's still possible. Also, their are other exposures to mercury:- broken CFL lamps, vaccines (this is controversial but it is a scientific fact that many contain thimerasol which is used as a preservative), bulbs.. many more. Their are many people on the ACC forums whom have never had amalgams who have found significant improvements/been cured from similar autoimmune conditions to POIS. Even a trip to a conventional dentist office exposes you.
Hi John

I read that you have to take the supplements every 3 hours, did you do this everyday for one year or did you take break?

Thanks

Hello,

ACC is to do an appropriate dose of ALA every 2-3 hours for atleast 63hrs (including throughout the night), you then take 3 days off. That's 1 round.

I've done over 70 rounds at this point. Tend to do a round a week.

Hi JohnJames,

The mercury makes alot of sense, seeing as it most likely causes mcas and histamine intolerance.

How is all of your POIS symptoms now and other health issues since your last activity on this post in February??

Also how many rounds  of ACC have you done so far?

Good actually, my life is slowly getting back on track, I've done over 70 rounds. My POIS is only bad for a day after orgasm, I'm getting more sociable and outgoing and sleeping much better. I have a girlfriend now, work 9-5, exercise, do weekend activities/have a social life, all of which would of been too tiresome or I would of been too depressed to do effectively before starting this process. I used to spend all day every day playing videogames, people are noticing differences in me, my mom said that I seem much happier and more content than I used to (I haven't told her about any of this).

Histamine and MCAS problems are extremely common in mercury toxic folk, so would make sense.

Interesting pose, but how is orgasm causing symptoms?

I don't know the exact pathway, but something is going wrong somewhere, and I think Mercury is behind it. Mercury damages many of the systems which come into play during orgasm/ejaculation (nervous system, endocrine system, etc).

Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Muon on July 14, 2020, 10:18:20 AM
VEGF:

Mercury chloride triggers human mast cells to release vascular endothelial growth factor (VEGF)-relevance to autism (38.26) (https://www.jimmunol.org/content/182/1_Supplement/38.26.short)

Mercury induces inflammatory mediator release from human mast cells (https://link.springer.com/article/10.1186/1742-2094-7-20)
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Clues on July 14, 2020, 01:02:45 PM
Just to add to the conversation: I'm suspecting mercury from dental amalgam is triggering my mast cells. Will post more info after I've experimented a bit more, but here's a quick summary:

* After a fair bit of research and experimentation I believe I've got a mast cell activation disorder
* Avoiding my triggers (notably orgasm, certain foods, very cold or very hot weather, exercise) helps, but I've constantly got low-level "background" symptoms regardless of triggers
* Pain in jaw for 20+ years where I used to have mercury amalgam fillings
* Read recent research (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523211/) indicating that Chlorella is very effective in removing mercury
* Started taking chlorella daily
* Immediately noticed physical effects, such as numbness and tingling in jaw and feet
* Have been taking it 1 month. Numbness/tingling has subsided, pre-existing skin lesions and inflammation look better. No obvious change to cognitive background symptoms so far. Have not tried orgasm
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Investigator on July 17, 2020, 07:28:35 AM
Clues, do you currently have amalgams or did you remove them already? I recommend removing them with a biological dentist who will take extra precautions - you want at least a rubber dam.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Clues on July 17, 2020, 12:59:58 PM
Investigator, funny you should ask: I went to the dentist today, for the first time in several years, and he discovered I actually still have a few amalgam fillings! Apparently the guy who removed my amalgam about 10 years ago didn't remove all of them. The remaining ones are 4 very small and superficial ones.

My (new) dentist seems attentive and thorough, and I've scheduled an appointment to have the fillings removed next week, using a rubber dam. Investigator, is there anything else I should be aware of or ask for other than a rubber dam?
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: devastated on July 18, 2020, 01:32:12 AM
@demografx :
Dear demo, do NORD Researchers have access to (or knowledge of) this kind of threads so that they will be taken into account during the study?
They might provide invaluable clues and hints that could greatly speed up the process of discovering the cause!

Btw, I had as much as 9 tooth fillings as a teenager (back in the 80s), which coincided with the onset of my POIS symptoms. Don't know if it's connected, but I'd better mention it.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: demografx on July 18, 2020, 07:35:59 AM
devastated, they do have access, but I’ll ask more.

What’s happening at Facebook in terms of recruiting future POIS study volunteers? Awareness level? Qualifying/passing the screening process successfully?
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: demografx on July 18, 2020, 08:35:22 PM
devastated,
From Liberos, POIS testing laboratory:

“We do have access, of course, but the project is limited to what we think are the most likely candidates to give us the most information for a first pass. Basically, we are contrasting two overarching theories of POIS that should answer the question "which of two paths should we follow". There will be many alternative, possible smaller paths that may be relevant for an individual or a few people, but our goal is to help the most people possible...that "average" POIS-er...for the first big study!”
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: devastated on July 19, 2020, 09:34:58 AM
Thank you demo for your prompt feedback!

Let's hope they will explore as many avenues as possible.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: demografx on July 19, 2020, 08:54:41 PM
devastated, you’re welcome.

Did you see my previous questions about Facebook?
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: JohnJames on July 20, 2020, 02:10:17 PM
Investigator, funny you should ask: I went to the dentist today, for the first time in several years, and he discovered I actually still have a few amalgam fillings! Apparently the guy who removed my amalgam about 10 years ago didn't remove all of them. The remaining ones are 4 very small and superficial ones.

My (new) dentist seems attentive and thorough, and I've scheduled an appointment to have the fillings removed next week, using a rubber dam. Investigator, is there anything else I should be aware of or ask for other than a rubber dam?

Hello Clues,

Your list of symptoms sounds like me 2 years ago.

Ask your dentist to ensure he removes all amalgam and to visibly inspect the tooth before refilling, you should also ask for bite-wings of the refilled teeth. He might be reluctant and charge you for the bite-wings but it's worth knowing the amalgam is gone, if any small specs remain you won't get better. If he mentions he doesn't want to subject you to unnecessary X-ray, note that modern bite-wing X-ray equipment subject you to less radiation than a plane ride.

Mercury only seems to be removed in significant amounts after all exposures are removed (so you need to ensure there are no specs left over).

You should also join the facebook group, there are admins who can help, and volunteer dentists who can check your bite-wing xrays for mercury specs.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Investigator on July 23, 2020, 03:26:57 AM
Investigator, funny you should ask: I went to the dentist today, for the first time in several years, and he discovered I actually still have a few amalgam fillings! Apparently the guy who removed my amalgam about 10 years ago didn't remove all of them. The remaining ones are 4 very small and superficial ones.

My (new) dentist seems attentive and thorough, and I've scheduled an appointment to have the fillings removed next week, using a rubber dam. Investigator, is there anything else I should be aware of or ask for other than a rubber dam?

The most important bit is the rubber dam. There are guidelines on the IAOMT webpage, they recommend extra precautions using special filtration systems. You may check for an IAOMT dentist in your area.

Another thing to keep in mind is "amalgam tattoos" - some people have them on the gums close to teeth that had amalgam for too long. It's like amalgama sucked into your gums. Any oral surgeon or most dentists can remove an amalgam tattoo if you have one, but you'll have to ask. You don't need precautions for the removal of these, there is no drilling. The danger from amalgam removal is the drilling of the amalgama filling into pieces. You can ask any family dentist to inspect if you have amalgam tattoos.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Investigator on July 23, 2020, 03:30:03 AM
When I said the most important bit is the rubber dam, I really meant the most important bit besides the aspiration!!! Of course, most important is the aspiration, but it's self-understood, most dentists will do it anyways, but wouldn't use a rubber dam by default.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: DEANNX on July 28, 2020, 10:52:36 AM
https://andy-cutler-chelation.com/mercury-detox-forums/viewtopic.php?f=2&t=191

people on the ACC forum is also discussing Niacin
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: demografx on July 28, 2020, 03:03:03 PM
DEANNX, what is ACC?
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: DEANNX on July 29, 2020, 01:15:19 AM
ACC is a method to chelate mercury
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: DEANNX on August 09, 2020, 08:38:35 AM
Just to add to the conversation: I'm suspecting mercury from dental amalgam is triggering my mast cells. Will post more info after I've experimented a bit more, but here's a quick summary:

* After a fair bit of research and experimentation I believe I've got a mast cell activation disorder
* Avoiding my triggers (notably orgasm, certain foods, very cold or very hot weather, exercise) helps, but I've constantly got low-level "background" symptoms regardless of triggers
* Pain in jaw for 20+ years where I used to have mercury amalgam fillings
* Read recent research (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523211/) indicating that Chlorella is very effective in removing mercury
* Started taking chlorella daily
* Immediately noticed physical effects, such as numbness and tingling in jaw and feet
* Have been taking it 1 month. Numbness/tingling has subsided, pre-existing skin lesions and inflammation look better. No obvious change to cognitive background symptoms so far. Have not tried orgasm
Hi

could you give us a update on your symptoms and how much chlorella do you take a day????

I started ACC method a month ago, its my 4 rounds this week, I too notice numbness and tingling in jaw and feet and hand at the start of every round, after 4 rounds I feel my skin improved a bit also seem to be not getting as many acnes after O but these could also just be better sleep and other factors, my nose and lip still swelling for weeks after orgasm also no improvement so far with cognitive.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Clues on August 09, 2020, 09:13:25 AM
No problem DEANNX, here is an update:

I take a total of 3g organic chlorella per day, in the form of two 0.5g tablets per meal. I tried taking 5g per day, but it felt a bit much. I had trouble sleeping, I had a fever-like feeling at night. The tingling and numbness would also be more intense.

With 3g per day, the skin lesions have continued to fade out, except on my calves. I don't think that's a coincidence: My feet are the only places I still feel the numbness and tingling, and still have weird cracked and dry skin. The cold sensitivity also seems more pronounced in my feet. I've got no scientific basis for this, but based on the feeling, I suspect mercury is gradually removed from my body, but that my feet/lower legs still have a lot.

About 1.5 months into the chlorella adventure, I tried an orgasm. The visible inflammation symptoms were there, but I felt pretty good in the days after. Definitely better than usual. However I tried another orgasm a week later, after which I had my usual shitty cognitive symptoms: fatigue, irritability, depression, etc. So POIS is not conclusively improved, however if it really is a mercury thing, there might be quite a bit of mercury in the bloodstream as I'm detoxing, and I'm guessing symptoms such as POIS may improve once most of the mercury is gone.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Clues on August 11, 2020, 06:16:35 AM
Another small update: I had my remaining 4 amalgam fillings removed today. Seemed pretty safe: They used a rubber dam for each tooth, and I had a breathing mask over my nose. Plus a few other precautions.

Will continue with the chlorella detox and report back.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: DEANNX on August 11, 2020, 08:31:52 AM
Thanks for the update Clues and good luck with your journey
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Hopeoneday on August 17, 2020, 06:41:05 AM
A long time pois suffer, had a miracle cure from pois, after his
homeophaty drug suddelnly started to working after 10 years
(he took out his amalgam filings!).
https://poiscenter.com/forums/index.php?topic=426.msg13402#msg13402
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: JohnJames on August 19, 2020, 02:26:28 PM
A long time pois suffer, had a miracle cure from pois, after his
homeophaty drug suddelnly started to working after 10 years
(he took out his amalgam filings!).
https://poiscenter.com/forums/index.php?topic=426.msg13402#msg13402

This individual may find symptoms worsen 3 to 6 months from when they removed their fillings, if they do, then that confirms that mercury is causing their POIS (dump/stall phase).
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: DEANNX on August 23, 2020, 07:25:56 AM
A long time pois suffer, had a miracle cure from pois, after his
homeophaty drug suddelnly started to working after 10 years
(he took out his amalgam filings!).
https://poiscenter.com/forums/index.php?topic=426.msg13402#msg13402

This individual may find symptoms worsen 3 to 6 months from when they removed their fillings, if they do, then that confirms that mercury is causing their POIS (dump/stall phase).

Hi John

how long into the ACC did the dump phase hit you??And how long before you get reduction on the duration of POIS??I competed 6 rounds with 50mg ALA, theres improvement on sleep and skin problems but i dont know if i should also expect shorter POIS as well, my POIS last for weeks.

Thanks
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Clues on August 25, 2020, 02:14:42 AM
JohnJames and Investigator, I didn't see your responses until now! Thank you both for responding.

Your list of symptoms sounds like me 2 years ago.

Ask your dentist to ensure he removes all amalgam and to visibly inspect the tooth before refilling, you should also ask for bite-wings of the refilled teeth. He might be reluctant and charge you for the bite-wings but it's worth knowing the amalgam is gone, if any small specs remain you won't get better. If he mentions he doesn't want to subject you to unnecessary X-ray, note that modern bite-wing X-ray equipment subject you to less radiation than a plane ride.

Mercury only seems to be removed in significant amounts after all exposures are removed (so you need to ensure there are no specs left over).

You should also join the facebook group, there are admins who can help, and volunteer dentists who can check your bite-wing xrays for mercury specs.

I've already removed the remaining fillings. I went to the dentist here in Norway who seems to be the most serious about amalgam removal. They used a respiration mask over the nose, and they said something about the air pressure making sure I was breathing through the mask and not the ambient air. Also, they were careful to remove the amalgam in big chunks and not create vapour or dust. Plus they were careful about the rubber dam.

I didn't get any "after" picture, but they did seem very thorough. Tbh I'm more worried about the much bigger amalgam fillings I removed about 10 years ago and whether anything may have been left over from those. There was nothing in evidence in the x-rays though.

You say my symptoms sound like you as of 2 years ago; How have they improved or changed since?

When I said the most important bit is the rubber dam, I really meant the most important bit besides the aspiration!!! Of course, most important is the aspiration, but it's self-understood, most dentists will do it anyways, but wouldn't use a rubber dam by default.

Investigator, I'm assuming you mean respiration? Yeah I did make sure to get that, thankfully, but it's sadly not the norm here! See details on the removal above.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: JohnJames on August 25, 2020, 07:10:07 AM
A long time pois suffer, had a miracle cure from pois, after his
homeophaty drug suddelnly started to working after 10 years
(he took out his amalgam filings!).
https://poiscenter.com/forums/index.php?topic=426.msg13402#msg13402

This individual may find symptoms worsen 3 to 6 months from when they removed their fillings, if they do, then that confirms that mercury is causing their POIS (dump/stall phase).

Hi John

how long into the ACC did the dump phase hit you??And how long before you get reduction on the duration of POIS??I competed 6 rounds with 50mg ALA, theres improvement on sleep and skin problems but i dont know if i should also expect shorter POIS as well, my POIS last for weeks.

Thanks

There seems to be a lot of individual variation, some people are done with the dump in just a few months or barely notice a dump, others find themselves in the dump for a year or 2. I've done over 80 rounds and still think I'm in the dump, the dump hit around 3 months in. I've had improvements from around round 40 or so.

If you are feeling effects on and off round, you are responding to chelation, I'm not sure when your POIS will disappear but for me progress was slow but does accumulate. I'd recommend keeping a dairy or log with a short description of how you felt and maybe a rating system for overall POIS-ness or mood etc so you can see improvement.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: JohnJames on August 25, 2020, 07:12:45 AM
JohnJames and Investigator, I didn't see your responses until now! Thank you both for responding.

Your list of symptoms sounds like me 2 years ago.

Ask your dentist to ensure he removes all amalgam and to visibly inspect the tooth before refilling, you should also ask for bite-wings of the refilled teeth. He might be reluctant and charge you for the bite-wings but it's worth knowing the amalgam is gone, if any small specs remain you won't get better. If he mentions he doesn't want to subject you to unnecessary X-ray, note that modern bite-wing X-ray equipment subject you to less radiation than a plane ride.

Mercury only seems to be removed in significant amounts after all exposures are removed (so you need to ensure there are no specs left over).

You should also join the facebook group, there are admins who can help, and volunteer dentists who can check your bite-wing xrays for mercury specs.

I've already removed the remaining fillings. I went to the dentist here in Norway who seems to be the most serious about amalgam removal. They used a respiration mask over the nose, and they said something about the air pressure making sure I was breathing through the mask and not the ambient air. Also, they were careful to remove the amalgam in big chunks and not create vapour or dust. Plus they were careful about the rubber dam.

I didn't get any "after" picture, but they did seem very thorough. Tbh I'm more worried about the much bigger amalgam fillings I removed about 10 years ago and whether anything may have been left over from those. There was nothing in evidence in the x-rays though.

You say my symptoms sound like you as of 2 years ago; How have they improved or changed since?

When I said the most important bit is the rubber dam, I really meant the most important bit besides the aspiration!!! Of course, most important is the aspiration, but it's self-understood, most dentists will do it anyways, but wouldn't use a rubber dam by default.

Investigator, I'm assuming you mean respiration? Yeah I did make sure to get that, thankfully, but it's sadly not the norm here! See details on the removal above.

Yes I only suffer bad POIS a day after ejaculation now, after 1 day I still have symptoms but they are much milder, I used to have crippling POIS that would last around a week or more and I was never fully 100%.

Other things improved inside and outside of POIS: skin, energy levels, sleep, social abilities.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: DEANNX on September 11, 2020, 06:58:17 AM
Hi John

Do you late for does often???How long can you be late for and still continue the round???

Thanks
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: JohnJames on September 28, 2020, 07:03:30 AM
Hi John

Do you late for does often???How long can you be late for and still continue the round???

Thanks

There's no exact line where it is ok and not ok to take a dose, but Andy suggested between an hour and an hour and a half late. I'm usually not later by 20 mins.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: 15yrsAndCounting on October 11, 2020, 02:07:59 PM
I did not understand what is ACC? Can someone explain please.
And what are the exact supplements that you guys are using , which is helping, can you guys please list it.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: JohnJames on October 12, 2020, 05:54:59 AM
I did not understand what is ACC? Can someone explain please.
And what are the exact supplements that you guys are using , which is helping, can you guys please list it.

Step 1: Remove all possible sources of ongoing mercury poisoning.

Usually dental amalgam fillings are the culprit though not always, these need to be removed safely by a dentist who knows what they are doing, IE uses hazmat suits, oxygen, dental dam, amalgam cut out in chunks, room is properly isolated/ventilated. After/During procedure digital intraoral bitewings must be checked for specks of amalgam that may have been left behind and these too must be removed. Failure to properly follow this step will result in you not improving or getting worse.

Step 2: Get on the Core 4 supplements: Magnesium, Vit C, Zinc, Vit E.

Other supplements/diets can also help reduce symptoms but YMMV.

Step 3: 3 months after ALL source of mercury have been removed, Take Alpha Lipoic Acid ALA every 2-3 hrs for 63 hrs. Dose to symptoms. This is 1 round.

Usually people start between 0.25-12mg of ALA. Only increase your dose when you feel no difference on round and off round. Don't increase your dose by more than 50% at a time. Don't be afraid to reduce your dose if you feel rough.

Step 4: Rest minimum 3 days between rounds.

Step 5: Repeat Step 3 to 5 until all symptoms are gone for 6 months on a high enough dose (usually 200-300 mg ALA). This usually takes years (2-8 years).

I've currently done around 90 rounds and I've still got a while to go but I'm doing way way better.

Usually you'll feel better after removal of mercury sources, then after 3 months you might feel like your improvements stall or you start to feel worse again, then if you continue chelating, after a while you will start feeling better again. There is a "dump/stall" phase that occurs usually around 3-6 months, this is thought to happen once blood levels of mercury reduce enough such that intracellular mercury then starts to mobilize.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Clues on October 12, 2020, 09:28:17 AM
JohnJames, I'm currently detoxing with chlorella and cilantro, and considering adding alpha lipoic acid to the mix. I see you're quoting the ACC chelation protocol. The last time I looked into that (10 years back) there didn't seem to be a lot of solid science behind that particular protocol. Googling ALA and detoxing now, I'm seeing some promising papers, but I was wondering whether the ACC protocol itself has ever been tested against others? I mean, how do we know for sure that taking breaks in between "rounds" is important for example?
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: DEANNX on October 16, 2020, 01:49:21 AM
I have finished 12 rounds of ALA, I haven?t had orgasm for 2 and half months now but recently I been experiencing depression and insomnia and get upset stomach when I am on round, not sure if that is the sign of dump phase or some other factor.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: JohnJames on October 17, 2020, 01:14:15 PM
JohnJames, I'm currently detoxing with chlorella and cilantro, and considering adding alpha lipoic acid to the mix. I see you're quoting the ACC chelation protocol. The last time I looked into that (10 years back) there didn't seem to be a lot of solid science behind that particular protocol. Googling ALA and detoxing now, I'm seeing some promising papers, but I was wondering whether the ACC protocol itself has ever been tested against others? I mean, how do we know for sure that taking breaks in between "rounds" is important for example?

Chlorella doesn't chelate. Cilantro we have no scientific method of dosing without avoiding redistribution as we don't understand it's pharmacokinetics. Both should be avoided ideally.

ACC was drawn up through interpretation of the literature on mercury removal, combined with the standard medical practice for dosing on a drugs pharmacokinetic half-life. There are many studies Andy cited which he drew from to form ACC.

Sure there are no Randomized Control Trials using ACC, but nor are their any for other methods of mercury removal. What ACC does have is thousands of people who have chelated and got better, no other method seems to boast the same amount of success.

If I remember correctly taking ALA increases bodily retention of copper taking the 3 day break allows the copper levels to settle, it's also why zinc is required to chelate, copper/zinc compete for the same receptors so taking one should reduce absorption of the other. We also know that redistribution of mercury takes around 3 days after chelating. This is verified theoretically, and backed by anecdotal experience.

Your questions are probably best directed to those on the ACC forums on facebook, there are people there whom are far more knowledgeable than me and a number of sources to read.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Hopeoneday on October 19, 2020, 12:34:26 PM
Chorella is potent naturall chelator:
https://www.google.com/search?client=firefox-b-d&q=is+chorela+chelator

But chorella cant penetrate in brain, thats why is used first to clean
toxins from body(NAC also wery potent),  then after that chelator for brain like chilantro or ALA.
learn about zeolite and odher chelators...
learn what is redistributinon when chelation start!
Learn what is binders and when to take them, like vit c ,
apple petcins etc...

Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Clues on October 20, 2020, 09:37:18 AM
JohnJames, thanks for your detailed response. I think it's been proven that chlorella does chelate mercury though, see this paper (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523211/).

Hopeoneday, thanks for your input as well.

Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: JohnJames on October 22, 2020, 09:56:06 AM
JohnJames, thanks for your detailed response. I think it's been proven that chlorella does chelate mercury though, see this paper (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523211/).

Hopeoneday, thanks for your input as well.

Chlorella does not chelate, Chelators have very specific chemical properties which causes mercury to chemically bond to the chelator. You can look at a molecule and determine whether or not it will or won't form a bond with mercury. Chelate/Chelation the word has a very specific meaning, substances which remove mercury doesn't mean they chelate mercury.

Chemistry is not my field of expertise so can't tell you much more.

With regards to the study, the study does not show that Chlorella chelates because it physically can't, it also doesn't show that Chlorella detox's mercury. However, it doesn't show that it does not detox mercury either.

If you read the method carefully, you'll see that during the 90 days of supplementation the patients removed their fillings, which means they changed more than 1 variable during the course of the study. The control group also did not have any amalgam fillings. The supplements they used was an entire regime, not just Chlorella, one such supplement they used was Selenium which has documented interactions with mercury. The study also only took 1 sample at d0 and d90 and did not monitor mercury levels throughout the entire process.

In order to prove Chlorella was doing something my guess is they'd have to compare a control group whom remove their fillings vs a group whom remove their fillings and take Chlorella.

It also only looked at blood levels of mercury. Mercury in the blood has a relatively low half-life (in the weeks) anyway and naturally decreases after removing ongoing exposures. Cellular mercury and mercury in the brain we don't know the half-life but estimations put it in the decades.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Clues on October 23, 2020, 01:36:06 AM
Chlorella does not chelate, Chelators have very specific chemical properties which causes mercury to chemically bond to the chelator. You can look at a molecule and determine whether or not it will or won't form a bond with mercury. Chelate/Chelation the word has a very specific meaning, substances which remove mercury doesn't mean they chelate mercury.

Oh, I see. I need to read up on this more.

The control group also did not have any amalgam fillings.
It also only looked at blood levels of mercury. Mercury in the blood has a relatively low half-life (in the weeks) anyway and naturally decreases after removing ongoing exposures.

Argh, that's really disappointing. I need to learn some more medical lingo so I can read these things properly.

Chlorella has definitely reduced some of my symptoms though. I guess it could be that 1. it does remove mercury by some yet-unknown mechanism or 2. it's helping my body in some completely unrelated way.

Here is another paper (https://link.springer.com/article/10.1007/s10811-020-02052-0) looking at chlorella and mercury removal, does this look like real research? I don't have the full article unfortunately.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: DEANNX on October 23, 2020, 01:42:06 AM
Hi John

I missed a late night does and had to stop the round then I wake up with brain fog is it normal? It kinda concerns me a little.

Thanks

Dean
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: JohnJames on October 23, 2020, 05:18:04 AM
Chlorella does not chelate, Chelators have very specific chemical properties which causes mercury to chemically bond to the chelator. You can look at a molecule and determine whether or not it will or won't form a bond with mercury. Chelate/Chelation the word has a very specific meaning, substances which remove mercury doesn't mean they chelate mercury.

Oh, I see. I need to read up on this more.

The control group also did not have any amalgam fillings.
It also only looked at blood levels of mercury. Mercury in the blood has a relatively low half-life (in the weeks) anyway and naturally decreases after removing ongoing exposures.

Argh, that's really disappointing. I need to learn some more medical lingo so I can read these things properly.

Chlorella has definitely reduced some of my symptoms though. I guess it could be that 1. it does remove mercury by some yet-unknown mechanism or 2. it's helping my body in some completely unrelated way.

Here is another paper (https://link.springer.com/article/10.1007/s10811-020-02052-0) looking at chlorella and mercury removal, does this look like real research? I don't have the full article unfortunately.

I think Chlorella is considered to be a binder, mercury and other things adsorb to the surface and in the gut which you then comes out in faeces. I would of thought other binders would also work such as Activated Charcoal. Problem is they just aren't going to remove mercury in the brain and in cells any more than would move naturally, which takes decades.

I think ACC actually thinks Chlorella is not harmful to take so doesn't have to be avoided, I think I misremembered in my post.

With all due respect Clues, how do you know some of the improvements you are having are from removing mercury exposure from your dental amalgams?

I don't have access to the full article so can't comment but from the abstract seems to confirm the above. The bit about mice seems very bizarre, looking at the pictures and reading the abstract.


Hi John

I missed a late night does and had to stop the round then I wake up with brain fog is it normal? It kinda concerns me a little.

Thanks

Dean

Yeah I have similar experiences when I miss doses.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Clues on October 23, 2020, 08:56:53 AM
With all due respect Clues, how do you know some of the improvements you are having are from removing mercury exposure from your dental amalgams?

Perfectly valid question JJ. I don't know for sure, it's just conjecture. There's more detail in my earlier posts in this thread, but basically I have symptoms that seems to match with mercury poisoning, and the chlorella immediately caused tingling and numbness in areas where I've had the most pain (jaw, lower back, feet), and over a few months it has alleviated some of my symptoms noticeably.

I'd welcome any tips on how to get myself tested.

Here is the full paper on SciHub (https://sci-hub.do/https://link.springer.com/article/10.1007/s10811-020-02052-0).
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: JohnJames on October 23, 2020, 10:23:40 AM
With all due respect Clues, how do you know some of the improvements you are having are from removing mercury exposure from your dental amalgams?

Perfectly valid question JJ. I don't know for sure, it's just conjecture. There's more detail in my earlier posts in this thread, but basically I have symptoms that seems to match with mercury poisoning, and the chlorella immediately caused tingling and numbness in areas where I've had the most pain (jaw, lower back, feet), and over a few months it has alleviated some of my symptoms noticeably.

I'd welcome any tips on how to get myself tested.

Here is the full paper on SciHub (https://sci-hub.do/https://link.springer.com/article/10.1007/s10811-020-02052-0).

The problem with this paper is that it doesn't state how the mercury dose was administered to the mice, and they began treatment immediately after exposure (Also the doses given to the mice seem VERY high). I would imagine if mercury was ingested by the mice, then the Chlorella may be particularly effective, since it does not get absorbed into the blood.

It takes a while after exposure for mercury to leave the bloodstream and into cells and organs (weeks for humans) and start causing damage, starting treatment immediately whilst mercury is still in the gut with binders may effectively prevent mercury from becoming intracellular and is excreted with the binder before that occurs. It does not show that Chlorella removes mercury from organs or from cells.

An example of this is below, note the timing of the symptoms appearing:
https://www.youtube.com/watch?v=NJ7M01jV058

In fact, the authors of the paper specifically address this in the discussion:

Quote
This indicates that
Chlorella effectively binds with mercury and facilitates
its excretion through faeces. As Chlorella does not absorb
through the gut, it excretes completely through the faeces.
The whole tissue retention of mercury was found to be
less, whereas elimination of mercury was high in
Chlorella-treated groups compared to control groups.
The sulphur-containing chelating agents DMPS and
DMSA have greater affinity for mercury and excrete
through the kidney by forming complex with mercury


Best test is to try chelating (I've covered tests on another post in this thread).

I think personal experience is important, and since it wasn't too long ago you removed your amalgams the Chlorella may be mopping up still floating around your gut from recent exposures.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Clues on October 28, 2020, 03:07:28 AM
JJ, thanks for your input.

The fillings I removed recently were in all likelihood not the biggest problem though. They were very small and stable, and were removed carefully. The ones I removed 10-ish years ago were much bigger, and one of them was noticeably worn down from chewing. Also, I've had my symptoms, including POIS, for at least 20 years. So if I do have a mercury issue, the mercury is probably everywhere by now.

I respect your skepticism about the efficacy of Chlorella, but it definitely feels like something is happening in my limbs and skin in particular, which I don't know how to explain unless something is being absorbed into my bloodstream and is affecting more than just my gut. I've read somewhere about detoxing mercury that the most readily-available mercury is removed first, and it feels like something like that is happening in my legs: When I first started taking Chlorella, my calves and feet were numb and tingly to the point where I stumbled while walking and had to reduce the dose. Then gradually, the tingling and numbness receded downwards, and now I only feel it in my feet, especially the bottom couple of inches from the ground.

One thing to note, I guess, is that I do take small amounts of cilantro with my food. I think I read somewhere (sorry, don't have a source) that garlic and a couple of other foods can also mobilise mercury, and I have been eating a fair bit of that as it helps the gut and helps against mast cell activity. So maybe those things are mobilising the mercury and the Chlorella is capturing it somehow? I don't know. But the net effect, whatever it is, is definitely positive so far, and as the risk seems low-to-nonexistent, I'll keep taking Chlorella for now.

I'll definitely consider chelating, but I'm hesitant to go there right now because 1. all the info I've found about ACC online seems anecdotal and I can't find any solid sources with even rudimentary research, 2. I'm on a very limited budget, and importing DMSA and buying the other supplements I'll need is a bit much considering I don't even know for sure if mercury is my problem. (Presumably I'd need mineral supplements? Or does DMSA only chelate the bad stuff?)

Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: JohnJames on October 29, 2020, 05:22:29 AM
Little update from me: ejaculated twice yesterday. Only symptom I have this morning is a bit of tiredness, and that might be because I went to bed a little late.

JJ, thanks for your input.

The fillings I removed recently were in all likelihood not the biggest problem though. They were very small and stable, and were removed carefully. The ones I removed 10-ish years ago were much bigger, and one of them was noticeably worn down from chewing. Also, I've had my symptoms, including POIS, for at least 20 years. So if I do have a mercury issue, the mercury is probably everywhere by now.

I respect your skepticism about the efficacy of Chlorella, but it definitely feels like something is happening in my limbs and skin in particular, which I don't know how to explain unless something is being absorbed into my bloodstream and is affecting more than just my gut. I've read somewhere about detoxing mercury that the most readily-available mercury is removed first, and it feels like something like that is happening in my legs: When I first started taking Chlorella, my calves and feet were numb and tingly to the point where I stumbled while walking and had to reduce the dose. Then gradually, the tingling and numbness receded downwards, and now I only feel it in my feet, especially the bottom couple of inches from the ground.

One thing to note, I guess, is that I do take small amounts of cilantro with my food. I think I read somewhere (sorry, don't have a source) that garlic and a couple of other foods can also mobilise mercury, and I have been eating a fair bit of that as it helps the gut and helps against mast cell activity. So maybe those things are mobilising the mercury and the Chlorella is capturing it somehow? I don't know. But the net effect, whatever it is, is definitely positive so far, and as the risk seems low-to-nonexistent, I'll keep taking Chlorella for now.

I'll definitely consider chelating, but I'm hesitant to go there right now because 1. all the info I've found about ACC online seems anecdotal and I can't find any solid sources with even rudimentary research, 2. I'm on a very limited budget, and importing DMSA and buying the other supplements I'll need is a bit much considering I don't even know for sure if mercury is my problem. (Presumably I'd need mineral supplements? Or does DMSA only chelate the bad stuff?)

Amalgams of any kind constantly off-gas mercury which you breathe in and absorb through your lungs. There is enough mercury in even a small amalgam filling to kill you many times over. Swallowing solid chunks of amalgam isn't actually that bad and doesn't get absorbed.

As stated before, there is a huge abundance of scientific evidence on the use of ALA and DMSA as chelating agents for curing mercury poisoning, which Andy drew upon the create ACC. In fact, there is far far less evidence on the use of Chlorella/Cilantro to cure mercury poisoning.

you don't need mineral supplements, on ACC you only need the core 4. ACC is very cheap to do, especially if you buy ALA powder in bulk and make your own tablets, but even if you don't it's still pretty cheap.

The way I see it: the only downside to ACC is cost, the upside is there's a possibility it cures your POIS. You'll figure out within a couple of rounds if it's doing anything or not (probably even the first round). To me it seems like a no brainer.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: DEANNX on October 29, 2020, 11:43:51 PM
Hi John, congrat on your progress, I remember your POIS last for two weeks, I wonder how many round it takes for your POIS duration to reduce by 1 day?
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: DEANNX on November 07, 2020, 04:43:57 AM
https://andy-cutler-chelation.com/mercury-detox-forums/viewtopic.php?f=2&t=277&hilit=selenium

just found a post about selenium and mercury on the mercury detox forum.

a guy said that selenium can redistribute mercury to somewhere it cant damage our health but doesnt chelate it.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Igy78 on November 17, 2020, 08:56:00 PM
Hi again, little feedback after a while, finally found the root cause of my problems, the liver, (probably mercury in there). Accidently, girlfriend said give this a try and i tried, taking 2 pill in the morning and 2 pill before sleep. I also have diagnosed fatty liver. Liver has 500 functions.

https://www.dietpharm.com/en/proizvodi/silimarin-articoka-kapsule/

Contains:    The recommended daily dose 1 capsule    % NRV*
Dry standardized extract of milk thistle fruit (Silybum marianum)    175 mg    -
containing silymarin    140 mg
Dry artichoke leaf extract (Cynara scolymus) with at least of 2% cynarin    100 mg    -
Vitamin E (D-alpha-tocopherol)    15 mg α-TE    125
Zinc (zinc oxide)    7,5 mg    75
Selenium (sodium selenite)    25 μg    45


One function of liver is to filter cortisol trough the day. Cortisol is high in the morning to wake us up, and if liver is sick or fatty, liver can not filter cortisol from blood, and i got all jittery, angry, suicidal, aggressive and irritable. Constantly in fight or flight mode. Normal range of cortisol in the mornings are from 250-450, mine is 850. If i drink caffeine, symptoms get extra pumped.  All that symptoms are always high in the morning. And i got better and better trough the day because liver slowly filter cortisol. These pills are helping liver to filter whatever liver need to filter. From all things i tried these are helping the most. I hope i maybe helped somebody.

Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: BoneBroth on November 18, 2020, 04:04:47 AM
A sluggish liver is certanly involved in the breakdown process from hormones (not only cortisol that is actually non-inflammatory). I always, 100% of time, get acne on my scalp and back on POIS and acne on the back is related to liver problems. The liver is also producing gall salts for fat metabolism and with a sluggish liver you will not absorb many B-vitamins properly - they are important for the whole hormonal balance. I've been taking supplements for the liver in periods after recommendations from therapists, but I don't experience much improvement from POIS. Maybe I should get on it again...
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Igy78 on November 18, 2020, 08:07:09 AM
A sluggish liver is certanly involved in the breakdown process from hormones (not only cortisol that is actually non-inflammatory). I always, 100% of time, get acne on my scalp and back on POIS and acne on the back is related to liver problems. The liver is also producing gall salts for fat metabolism and with a sluggish liver you will not absorb many B-vitamins properly - they are important for the whole hormonal balance. I've been taking supplements for the liver in periods after recommendations from therapists, but I don't experience much improvement from POIS. Maybe I should get on it again...

I found out that i feel better with 2 pills than on 1, so quantity plays major role, thanks also for your info about liver.  :)
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: quikot on November 24, 2020, 10:11:50 AM
Would blood/urine/saliva/hair tests uncover mercury toxicity from dental fillings? If mercury is the problem then it should show up on such tests, right?
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Journey on November 24, 2020, 12:36:13 PM
I haven't ever had mercury fillings nor been in contact with heavy metals or anything like that as far as I know yet I got POIS so I don't know what causes that for me?
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: DEANNX on November 24, 2020, 09:02:31 PM
Would blood/urine/saliva/hair tests uncover mercury toxicity from dental fillings? If mercury is the problem then it should show up on such tests, right?
?Mercury poisoning is difficult to determine because mercury hides. Thus trying to figure out whether someone has mercury poisoning is not an easy, direct thing to do, though many doctors will tell you it is.  One cannot simply test someone?s hair, or blood, or urine, or faeces, and measure how much mercury is there, and go by that. Why not? The body?s tissues are selective about how long they keep mercury inside themselves. Mercury will stay in some body tissues (such as the brain and liver) which are very attracted to it, for a long time. Other tissues (such as blood), will clear out the mercury pretty quickly. Blood will keep mercury for a few months, while the brain keeps it for a lifetime.Other tissues are in between.At first (soon after exposure), mercury is present in hair and blood. This means that soon after someone is poisoned, their blood and hair will probably show high levels of mercury. But later, in most cases, the mercury is ?hidden? deep within the body and it is no longer present in the blood or hair or urine or faeces. However, it is still present in other areas (such as the brain) and is still doing damage there. For people who have been exposed to mercury through vaccines (thimerosal) or through amalgam (dental fillings), the exposure is usually too far in the past and/or too slow and chronic for mercury to show up in hair or blood or urine or faeces.IMPORTANT:A PERSON WHO IS MERCURY TOXIC will often have a NORMAL reading for mercury on tests of hair or blood or urine or faeces. You cannot go by that. The most recent edition of many medical textbooks tell physicians that mercury poisoning cannot be ruled out based on the urine or blood level of mercury. This is also true for hair levels of mercury. Only about 1 poisoned person in 10 shows up with a high level of mercury on these tests. The other 9 poisoned people have normal readings for mercury.If the reading for mercury is HIGH (red) on a hair test, this probably indicates the person has mercury poisoning. On the other hand, if the reading for mercury is normal (or even very low), this indicates nothing one way or another about whether the person has mercury poisoning. Mercury can still be present in the brain and organs, doing lots of damage there, and ? NOT be present in the hair. THIS IS VERY COMMON?. [Source: Moria]?
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: quikot on November 24, 2020, 09:57:39 PM
DEANNX, so there is no reliable method to test for elevated mercury? Not even a saliva test? Since saliva is in the mouth next to the fillings?

I have a history of oral symptoms (metallic taste in mouth, gum disease, mouth ulcers, plaque) and that's despite high quality, obsessive dental care. So if fillings really are the source of toxicity, shouldn't a saliva test show elevated mercury levels?

I mean, to remove my fillings and replace them with composite ones, that's a lot of money to spend on something which I'm not even 100% sure is a problem. And procedure itself carries risk of exposure to lethal levels of mercury...
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: DEANNX on November 24, 2020, 10:14:51 PM
DEANNX, so there is no reliable method to test for elevated mercury? Not even a saliva test? Since saliva is in the mouth next to the fillings?

I have a history of oral symptoms (metallic taste in mouth, gum disease, mouth ulcers, plaque) and that's despite high quality, obsessive dental care. So if fillings really are the source of toxicity, shouldn't a saliva test show elevated mercury levels?

I mean, to remove my fillings and replace them with composite ones, that's a lot of money to spend on something which I'm not even 100% sure is a problem. And procedure itself carries risk of exposure to lethal levels of mercury...

As far as I know There?s two ways of showing whether you are likely to be mercury toxic according to Andy culter, one is to do hair elements test(I think the idea is that you might be toxic if your hair is low on some elements while high on some) and the other one is to try the ACC protocol and see if you react to it, you can learn more on https://andy-cutler-chelation.com/

Also according to Andy cutler, you can not do the ACC protocol if you still have fillings in your mouth, it will make you worse, the ACC protocol can only be done 3 months after you have fillings removed
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Igy78 on December 08, 2020, 08:14:13 AM
Hi ppl, little feedback from me because i feel better and better from last time i wrote here, i bombarded the liver with silymarin and artichoke and i feel better, even with orgasm every day, so it's a day and night difference from chronic fatigue, anxiety, suicidal thoughts i had before. I'm not cured yet but i'm on the right track. I found out that the fatty livers are not producing enough bile, well, bile is extra important because it regulates good and bad bacteria and preventing migration of bacteria (sibo), cleaning the fat from colon, without bile there is no absorption fat soluble vitamins and omega 3, and then you get POIS, every time i drink 2 tabletes of artichoke in 45 minutes i feel better, brain fog is cleared and got sense of well being. I'm not irritable, angry, aggressive. You can take a ton of vitamins but if there is no absorption then it's not usefull. I found one very usefull text about liver, bile and sibo.

https://hackyourgut.com/2016/11/03/10-reasons-why-people-with-sibo-should-care-about-bile/

and useful video how to increase bile.

https://www.youtube.com/watch?v=h64_7DYf5_0

Probably liver stops producing bile because of heavy metal toxicity, without bile there is no detox either.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Journey on December 08, 2020, 08:23:22 AM
Hi ppl, little feedback from me because i feel better and better from last time i wrote here, i bombarded the liver with silymarin and artichoke and i feel better, even with orgasm every day, so it's a day and night difference from chronic fatigue, anxiety, suicidal thoughts i had before. I'm not cured yet but i'm on the right track. I found out that the fatty livers are not producing enough bile, well, bile is extra important because it regulates good and bad bacteria and preventing migration of bacteria (sibo), cleaning the fat from colon, without bile there is no absorption fat soluble vitamins and omega 3, and then you get POIS, every time i drink 2 tabletes of artichoke in 45 minutes i feel better, brain fog is cleared and got sense of well being. I'm not irritable, angry, aggressive. You can take a ton of vitamins but if there is no absorption then it's not usefull. I found one very usefull text about liver, bile and sibo.

https://hackyourgut.com/2016/11/03/10-reasons-why-people-with-sibo-should-care-about-bile/

and useful video how to increase bile.

https://www.youtube.com/watch?v=h64_7DYf5_0

Probably liver stops producing bile because of heavy metal toxicity, without bile there is no detox either.
I often have green and yellow stools especially in POIS and they tend to be liquidish too which could mean a weaker bile production I wonder why we have that in the first place what is the root cause for weaker bile production and why in POIS it happens more?
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: BoneBroth on December 09, 2020, 03:41:56 AM
Good question! I also have yellowish stools in pois. Maybe an ox-bile supplement would temporary fix this. I think constant inflammation is the cause of impairment of the liver, where the bile is produced. However the liver has an amazing ability to heal itself.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Muon on December 09, 2020, 08:49:17 AM
Aren't broccoli sprouts good detoxers?
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Investigator on December 12, 2020, 07:55:46 AM
I bombarded the liver with silymarin and artichoke and i feel better, even with orgasm every day, so it's a day and night difference from chronic fatigue, anxiety, suicidal thoughts i had before. I'm not cured yet but i'm on the right track.

Igy78, it's very encouraging to hear this. What dose of silymarin did you take to "bombard" the liver? As of today, I am starting a course of 300mg silymarin per day that I plan for 25 days. I will then report how it goes.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Igy78 on December 12, 2020, 08:06:32 AM
Hi, i'm taking these pills, 2 in the morning and 2 afternoon. From everything i tried those are helping the most. Scroll down for ingredients. I did also tried pills from same company without zinc and selen with only silymarin and artichoke to narrow the ingredients that helped me, same effect, so definitely what is helping is silymarin and artichoke in my case. Also thinking to buy Ox bile and will try that also.

https://www.dietpharm.com/en/proizvodi/silimarin-articoka-kapsule/#
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Investigator on December 12, 2020, 08:42:56 AM
Thanks! I will go with 2x150mg=300mg per day for now (that is, half of what you're taking). Mine are only silymarin, no artishock, let's see how it goes. I take zink and selenium every day anyways now (also as covid prophylaxis). I've read some good stuff about silymarin, it sounds relevant for us, that's why I decided to start a course. 

For how long have you been taking these pills? You sound like you've been doing it for a while, if you used a different pack without zink and selenium. And then follow-up questions: have you tried a smaller dose to see if it helps as well (e.g. 2 of your tablets per day)? And most importantly, what happens if you stop the pills?

Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Igy78 on December 12, 2020, 10:03:40 AM
Thanks! I will go with 2x150mg=300mg per day for now (that is, half of what you're taking). Mine are only silymarin, no artishock, let's see how it goes. I take zink and selenium every day anyways now (also as covid prophylaxis). I've read some good stuff about silymarin, it sounds relevant for us, that's why I decided to start a course. 

For how long have you been taking these pills? You sound like you've been doing it for a while, if you used a different pack without zink and selenium. And then follow-up questions: have you tried a smaller dose to see if it helps as well (e.g. 2 of your tablets per day)? And most importantly, what happens if you stop the pills?

After 1-2 day i started to feel better, using this for a month, i did start with one pill and i sensed that i'm feeling better, then i up the dose to 2 pills and feeling even better, if i stop using symptoms are slowly coming back, it's like these pills are helping liver to detox and to produce bile and clean toxic stuff from blood. I suggest that you are try to start using artichoke also. What i also noticed it's that if i do not fart for a period of time i feel bad, as soon as i started to fart in a period of time 6-8 hours i feel better, same goes with growling in stomach, when it's growling i'm better, so all that is connected to lack of bile/fatty liver, with lack of bile you can not get proper stomach acid and lack of bile do not regulate bad bacteria in colon and i get overgrowth, and after 45 minutes to 2 hour after those pills i'm starting to fart and start having growls in stomach, so that pills are helping liver to make bile which regulates bad bacteria to not produce methan or hydrogen and everything is ok, i'm 95% sure that's the problem at least in my case. Also using betain hcl pills, about 5 per day, betain also helps for producing bile.

And also when i eat fruit with high fructose, or chocolate with sugars, rafaelo, nutella, or sugary soda, also food high in fat, that all is attacking my fatty liver and i almost immediately feel bad. So i am avoiding all that crappy food. I'm on a diet for fatty liver, moderate fat, lots of protein and low carb until i fix fatty liver, i hope it will be in the next 6 months.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Investigator on December 12, 2020, 01:10:16 PM
That's very interesting, indeed. Some time ago I made an oxidative damage test that showed elevated levels of lipid peroxides (https://poiscenter.com/forums/index.php?topic=3184.msg32675#msg32675 (https://poiscenter.com/forums/index.php?topic=3184.msg32675#msg32675)). Let's see if silymarin acts on that.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Igy78 on December 12, 2020, 03:32:26 PM
That's very interesting, indeed. Some time ago I made an oxidative damage test that showed elevated levels of lipid peroxides (https://poiscenter.com/forums/index.php?topic=3184.msg32675#msg32675 (https://poiscenter.com/forums/index.php?topic=3184.msg32675#msg32675)). Let's see if silymarin acts on that.

Yes, just bombard your liver with whatever you can, i forgot to say that liver also regulates cortisol in blood, it filters it, if it can not filter quick, then i get iritable, angry, agressive, i have most symptoms in the morning, becuase cortisol is needed to wake us up. My liver can not also filter fat fast, if i eat greasy bacon after 3-4 hours symptoms coming back, amazing organ, and mine decided to be sluggish and stubborn :). Wish you all the best with liver supplements.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Muon on December 17, 2020, 06:05:03 PM
Robbie Williams 'almost died with mercury poisoning due to extreme seafood diet' (https://www.mirror.co.uk/3am/celebrity-news/robbie-williams-almost-died-mercury-23180263)
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: DEANNX on December 26, 2020, 10:43:39 AM
after following the ACC protocol for almost 6 months, I see a 30%-50% improvement on some of my POIS symptoms like tinnitus, upset stomach and skin problems, and I dont have yellow snot and dark cycle under eyes from POIS anymore. but still no noticeable improvement on mental symptoms.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Hopeoneday on December 26, 2020, 12:52:48 PM
This are exelent results.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Investigator on December 26, 2020, 03:00:20 PM
...I also have diagnosed fatty liver. ...

Igy78, how did you get a diagnosed fatty liver? Was it through a blood test? Or an ultrasound? I would be willing to do a test for fatty liver, too.

I like your fatty liver theory, because a number of clues come together:
1) this whole mercury toxicity idea -> maybe that's what caused damage to the liver.
2) I get drunk super easily, from very little alcohol. Others have reported similar observations here. Maybe something is wrong with the liver.
3) I have lots of body fat, and I had that even when I was exercising suuuuper super active cardio (way before my POIS started). This maybe hints at a problem with absorption.
4) I've done a nails test for metals and minerals and I have deficiency in essential nutrients in nails. Now, I think I have them in good quantities in blood, so the problem is with storage and transport, not with insufficient nutrition. (Note that Andy Cutler talks about how mercury may cause deranged mineral transport.)
5) While in POIS, it really feels to me like I am lacking fuel. I eat and it feels like food is not going where it should, not transformed into energy.
6) Finally, all this Vitamin D stuff here on the forum, I think we have problems with the absorption of Vitamin D (if we supply it through supplements - that's why sun is better for many of us). 

That's why I would definitely be interested in doing a test for fatty liver.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Igy78 on December 27, 2020, 07:25:12 PM
...I also have diagnosed fatty liver. ...

Igy78, how did you get a diagnosed fatty liver? Was it through a blood test? Or an ultrasound? I would be willing to do a test for fatty liver, too.

I like your fatty liver theory, because a number of clues come together:
1) this whole mercury toxicity idea -> maybe that's what caused damage to the liver.
2) I get drunk super easily, from very little alcohol. Others have reported similar observations here. Maybe something is wrong with the liver.
3) I have lots of body fat, and I had that even when I was exercising suuuuper super active cardio (way before my POIS started). This maybe hints at a problem with absorption.
4) I've done a nails test for metals and minerals and I have deficiency in essential nutrients in nails. Now, I think I have them in good quantities in blood, so the problem is with storage and transport, not with insufficient nutrition. (Note that Andy Cutler talks about how mercury may cause deranged mineral transport.)
5) While in POIS, it really feels to me like I am lacking fuel. I eat and it feels like food is not going where it should, not transformed into energy.
6) Finally, all this Vitamin D stuff here on the forum, I think we have problems with the absorption of Vitamin D (if we supply it through supplements - that's why sun is better for many of us). 

That's why I would definitely be interested in doing a test for fatty liver.

Yes, you did say right about fatty liver theory, "because a number of clues come together". Have almost all of your symptoms and was very low on vitamin D. I had amalgam in my mouth and i was on e-cig for one year (3 years a go) and symptoms got worse 300%, because i thought e-cig was healthier than cigarette (started cigarette at 17 years of age) and i was inhaling e-cig like a madman, every 10 seconds inhaling each (whole) day one year. And in that period i did notice that i am irritable, aggressive, easily annoyed more than ever!. That's probably a way that mercury find a way into organs. It's a hot vape that in contact with amalgam released mercury that came direct into my lungs and other organs. I did lost hair on top of my head for about 30-40% in that period. And started sometimes to bleed from my gums (vitamin K deficiency/fat soluble vitamin).

https://www.youtube.com/watch?v=2RnIS693CrM   - smoking tooth with amalgams.

My hair test for mercury came positive. I did 30 rounds of chelating of ACC protocol and i can say that i feel a little better than before, but not good as when i take 2 pills of syllimarin and artichoke. I feel great after 45 minutes to 1 hour. Brain fog stops, and i am like i never had any symptoms. After a month and a half of that pills i am more convinced that mercury are culprit for lack of bile in my case, mercury probably interfering with liver or gallbladder for producing/releasing bile. I did make a test, i eat greasy bacon and butter (cake with a lot of butter) without those pills and after 3-4 hours when that grease/fat came into colon, symptoms came back, anxiety, suicidal thoughts, irritable, aggressive. With no bile there is no absorption of vitamins, no order in gut bacteria. Next day i eat the same with those pills and i had no symptoms, so all leads to a problem with bile. It's like magic pill that jumpstart liver to produce bile.  No more restless legs symptoms after eating Nutella and Mcdonalds. I was shocked.

Regarding your question, i did not know what was wrong with me, and at some point i get ultrasound of abdomen and doctor said that i have fatty liver, and i asked on a scale from 1/10 she said 6/10, enlarged. Almost all my life i have fatty liver. I remember in my childhood that i had a very bad diet, everyday a ton of french fries with 2 liters of cola and sausages and ton of mayo and when i get 16/17 years of age i started to drink on weekends up to 3-4 litres of vine mixed with cola, and other alcohol until age of 33. I declared war on my liver without even knowing it. I thought all that stuff was not harmful. I started to develop psoriasis on a skin at age 19 and still have psoriasis and psoriasis nails (42 now) and had all symptoms above but very very mild. Could not keep eye contact while talking, got very fatigued while talking and could not keep conversation due fatigue. And all that problems started to maximize a lot when i started e-cig.

If you have fat below belly button you have fatty liver that is if you can not see your dick you have fatty liver :). I have 120 kg, height 1.88 cm. Looking normal/little fatty, not obese. (BMI says that i am obese).

And regarding cravings, i have serious craving for food, i am constantly hungry until i do enema (oregano oil), it's very weird but it works, its like enema washes something from colon (maybe candida or fat mucus) and no cravings anymore- almost same thing happens with those pills. Also it could be that my body is sending signals to eat due to malabsorption of food/vitamins and so on.

I ordered Ox bile to try that also. I read very positive comments on Amazon. I can not wait to try it :). With out bile liver can not detox. Here is one comment from Amazon from one girl after taking Ox bile.

"This pill has changed my life! I have had gallbladder issues for years, but didn?t realize how much it was affecting me overall. Recently I had been feeling fatigued, sluggish, bloated and overall kind of blah. I had been reading about the benefits of ox bile, but I?m a skeptical person by nature. I decided to try these to see if I really noticed any difference. Did I ever! My digestive upset is gone. My bloating and gas are gone. I have energy like I?ve never felt before. My brain feels functional and I don?t have any mental fog or sluggishness. I highly recommend this if you have any of the above symptoms. Definitely start slow and work your way up. It does have an unpleasant taste if you don?t swallow the pills right away, but I?ll take the unpleasant taste if it helps me feel better. "

https://www.amazon.com/Ox-Bile-125-180-Capsules/product-reviews/B003GHA5GS/ref=cm_cr_getr_d_paging_btm_next_4?ie=UTF8&reviewerType=all_reviews&pageNumber=4


Regarding stool. Still constipated, i go every second day on the toilet. I have greenish color of stool with very dry lumps like a shit from Goat, which floats in toilet. Sometimes i feel pain when i take a shit because of huge stool. All that are symptoms of bile deficiency, how is your stool?



Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: JohnJames on December 27, 2020, 08:18:52 PM
...I also have diagnosed fatty liver. ...

Igy78, how did you get a diagnosed fatty liver? Was it through a blood test? Or an ultrasound? I would be willing to do a test for fatty liver, too.

I like your fatty liver theory, because a number of clues come together:
1) this whole mercury toxicity idea -> maybe that's what caused damage to the liver.
2) I get drunk super easily, from very little alcohol. Others have reported similar observations here. Maybe something is wrong with the liver.
3) I have lots of body fat, and I had that even when I was exercising suuuuper super active cardio (way before my POIS started). This maybe hints at a problem with absorption.
4) I've done a nails test for metals and minerals and I have deficiency in essential nutrients in nails. Now, I think I have them in good quantities in blood, so the problem is with storage and transport, not with insufficient nutrition. (Note that Andy Cutler talks about how mercury may cause deranged mineral transport.)
5) While in POIS, it really feels to me like I am lacking fuel. I eat and it feels like food is not going where it should, not transformed into energy.
6) Finally, all this Vitamin D stuff here on the forum, I think we have problems with the absorption of Vitamin D (if we supply it through supplements - that's why sun is better for many of us). 

That's why I would definitely be interested in doing a test for fatty liver.

Point number 5, mercury induces mitochondrial dysfunction. This could be related.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Investigator on December 28, 2020, 09:27:20 AM
Thanks for the detailed answer, Igy78! I see, so you had a fatty liver diagnosis via ultrasound and by a conventional doctor, that's good to know. I should do an ultrasound for the liver then, too. But I don't think I have most of the other symptoms you describe. I see nothing unusual with my stool. Food cravings I only have during POIS and explain them with the general lack of energy. I do have belly fat below belly button, but I think many people have it, I wouldn't say it's a definite diagnosis of fatty liver (although it could be a cue). It may be because I am not as active as I would have been without POIS (and also because while in POIS, I eat a lot).

It sounds like you either figured out what was going wrong with you, or, at the very least, you're on the right track. That's very encouraging news, great to hear that. From what I know, the liver is a very strong organ, so let's hope that with sufficient support and without unnecessary overload, it will eventually help you clean out the accumulated toxins (this may take some time). 
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Igy78 on December 28, 2020, 10:14:27 AM
This could also help. I have gynecomastia.

https://www.youtube.com/watch?v=Dz0-E6biHSw
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Igy78 on January 02, 2021, 10:59:04 AM
Hi guys, little feedback about bile salts, lack of bile in liver. Some of you know that i'm using syllimarin and artichoke and that i feel better because that those suplements kickstart bile production in liver and i said that i will try Ox bile.

Ox bile came 3 days a go, and in these 3 days i can say that bile salts has completely replaced the effect of syllimarin and artichoke, even for the better. I did not use syllimarin and artichoke while i was testing ox bile. Side effects of using bile salts are diarrhea, i munched even 6 pills in a day ( 750mg) and i did not have any symptoms of diarrhea. That's possible indicator that my body was heavily lacking bile. My stool is coming back to normal, i noticed that now half of my stool was normal color and texture and half was lumpy and more greener than usual.

So in my case diagnose is, lack of bile due to heavy metal toxicity, where metabolism could not digest fat, could not absorb omega 3, vitamin a, k , d, e. No bile no detoxing, chaos regarding bad/good bacteria in the gut. Anyway i am more relaxed, more talkative, not so angry anymore, not so irritable anymore and little to no brainfog. (Still,  if i eat cured meat, potato chips, huge amount of dairy, i get little symptoms back, i probably need to increase the dose of bile salts, still experimenting on doses and i feel the best on keto diet/moderate fat.) Have more and more bowel sounds and stomach sounds (also farts) so something is happening for the better where before i did not have any of that.

One important thing is when i eat ox bile, after a while I feel the same symptoms as when I ate vitamin niacin/b3, some kind of flush trough the skin, it lasts  maybe for 5-10 minutes.

Yesterday i talked to my girlfriend for about 2 hours, she is surprised how much energy did i have. Usually i was talking for 5-10 minutes over the phone and get exhausted and irritable.

Will try to experiment with doses and surely will give feedback every now and then because i know what crap POIS is and i feel sorry for all of you and i want to help you with my experience.

Happy new year and all the best guys. I did learn a lot from you all and this forum.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: aswinpras06 on January 02, 2021, 09:20:37 PM
This is really a good news Igy78.

Many of our members have malabsorption problems and if it is corrected their  health will improve   and pois symptoms also will be decreased. How do you take the bile salt capsules. Before food or after food.  Also each capsule 750 mg or total of 6 capsules is 750 mg.  I have a bottle of Jarrows formula bile acid factors.  In that 4 capsules provide 1000mg of total bile acid and 945mg of conjugated bile acid. 

Also long term use of bile capsules is not recommended by doctors.  But still we cannot have continuous malabsorption which is more risky than bile acids.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Iwillbeatthis on January 03, 2021, 01:04:19 PM
Hi guys, little feedback about bile salts, lack of bile in liver. Some of you know that i'm using syllimarin and artichoke and that i feel better because that those suplements kickstart bile production in liver and i said that i will try Ox bile.

Ox bile came 3 days a go, and in these 3 days i can say that bile salts has completely replaced the effect of syllimarin and artichoke, even for the better. I did not use syllimarin and artichoke while i was testing ox bile. Side effects of using bile salts are diarrhea, i munched even 6 pills in a day ( 750mg) and i did not have any symptoms of diarrhea. That's possible indicator that my body was heavily lacking bile. My stool is coming back to normal, i noticed that now half of my stool was normal color and texture and half was lumpy and more greener than usual.

So in my case diagnose is, lack of bile due to heavy metal toxicity, where metabolism could not digest fat, could not absorb omega 3, vitamin a, k , d, e. No bile no detoxing, chaos regarding bad/good bacteria in the gut. Anyway i am more relaxed, more talkative, not so angry anymore, not so irritable anymore and little to no brainfog. (Still,  if i eat cured meat, potato chips, huge amount of dairy, i get little symptoms back, i probably need to increase the dose of bile salts, still experimenting on doses and i feel the best on keto diet/moderate fat.) Have more and more bowel sounds and stomach sounds (also farts) so something is happening for the better where before i did not have any of that.

One important thing is when i eat ox bile, after a while I feel the same symptoms as when I ate vitamin niacin/b3, some kind of flush trough the skin, it lasts  maybe for 5-10 minutes.

Yesterday i talked to my girlfriend for about 2 hours, she is surprised how much energy did i have. Usually i was talking for 5-10 minutes over the phone and get exhausted and irritable.

Will try to experiment with doses and surely will give feedback every now and then because i know what crap POIS is and i feel sorry for all of you and i want to help you with my experience.

Happy new year and all the best guys. I did learn a lot from you all and this forum.

I saw a box of liver detox pills with artichoke, milk thistle , dandelion on clearance so I bought them after seeing your post. It improves my stools a lot while I'm taking but I haven't seen much improvements with brain fog etc. I remember when I took just milk thistle in the past it was also similar.

Four years ago when I had CT scan it showed I had gall bladder stones but they were non invasive maybe that could be affecting my bile production in the gall bladder.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Igy78 on January 03, 2021, 02:01:02 PM
This is really a good news Igy78.

Many of our members have malabsorption problems and if it is corrected their  health will improve   and pois symptoms also will be decreased. How do you take the bile salt capsules. Before food or after food.  Also each capsule 750 mg or total of 6 capsules is 750 mg.  I have a bottle of Jarrows formula bile acid factors.  In that 4 capsules provide 1000mg of total bile acid and 945mg of conjugated bile acid. 

Also long term use of bile capsules is not recommended by doctors.  But still we cannot have continuous malabsorption which is more risky than bile acids.

Hi, 1 pill is 125 mg, i ordered bottle where 1 pill have 500 mg, i eat in the morning 3-4 pills, at 15h, 2 pills and before sleep 2 pills, still experimenting with doses, i increased dosage to 12  (4-4-4)pills a day today, will sure give feedback. I will test how many pills i can eat before pills give me diarrhea so i can find sweetspot.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Igy78 on January 03, 2021, 02:06:56 PM

I saw a box of liver detox pills with artichoke, milk thistle , dandelion on clearance so I bought them after seeing your post. It improves my stools a lot while I'm taking but I haven't seen much improvements with brain fog etc. I remember when I took just milk thistle in the past it was also similar.

Four years ago when I had CT scan it showed I had gall bladder stones but they were non invasive maybe that could be affecting my bile production in the gall bladder.

Well, healing liver if you have fatty liver does not come overnight, when i discovered syllimarin and artichoke pills i eat just one, and i sensed that in some moments my mind feel sharp, then i increased the dosage to two in the morning and 1  at 15h and 1 before sleep. I tried every vitamin suplement in existence. Minerals,zinc, copper, and nothing helped like artichoke and syllmarin, i feel even better if i avoid dairy and processed food, so try to avoid that for a week.

Did you test for fatty liver? Fatty liver does not produce enough bile.

Regarding gallstones. It can block or reduce bile flow. Pills you say you eat is the best for your liver and can only help you, can not do any harm, so that's positive :). I found 10 things on youtube that is helping liver, and i tried dandelion but did not feel better with dandelion. And some guy on youtube said that dandelion helped him. So it's all trial and error but with sylimarin and artichoke we can not miss. Those two ingredients are on the top of pyramid.

https://www.nhs.uk/conditions/gallstones/complications/

All the best.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: ascorbate on January 03, 2021, 09:00:38 PM
I've had POIS since I was 13. I am now 27. I developed POIS right at the time I became mercury toxic from amalgams. I also developed major candida and gut dysbiosis problems at this time, presumably from mercury toxicity.

I chelated for a few years. My POIS got better, but not drastically. I then went downhill again health wise and have now attributed it to mold exposure in my home. It was ripped up and remediated, but I am still suffering with symptoms from it.

I am both mercury and mold toxic, with lots of gut and adrenal problems. I am in the process of pursuing "extreme mold avoidance" and leaving my belongings behind and living in a trailer. I am 100% convinced that mercury is behind my POIS. For about 7 days after orgasm I have a major increase in my symptoms associated with mercury toxicity. Depression, fatigue, apathy, weakness, dizzyness, light headedness, sense of doom, etc. This starts to improve around day 7 and continues to improve for a few days after that.

I need to get back to chelating as that was the only thing that really helped. Using the Cutler protocol. But as of now, this mold issue is pressing. There's lots of stories of people exposed to minute amounts of mold that would not bother certain people, but those who are very sensitive to it get whacked by it and have all sorts of symptoms similar to the ones we describe here. I am pursuing the mold theory as of now.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: aswinpras06 on January 03, 2021, 09:16:28 PM
Thanks Igy78.  I am currently starting with 250mg of bile acid before each meal.  Will report the results in a weeks time.  If it works then I may gain some strength to walk.  I am now bedridden
for about 8 months due to allergic fungal infection of my lungs which have destroyed about 70% of my lungs.  I am following a low histamine diet to avoid chest congestion and could not gain any weight inspite of drinking high fat supplement powders and high fat foods.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Igy78 on January 03, 2021, 10:17:01 PM
I've had POIS since I was 13. I am now 27. I developed POIS right at the time I became mercury toxic from amalgams. I also developed major candida and gut dysbiosis problems at this time, presumably from mercury toxicity.

I chelated for a few years. My POIS got better, but not drastically. I then went downhill again health wise and have now attributed it to mold exposure in my home. It was ripped up and remediated, but I am still suffering with symptoms from it.

I am both mercury and mold toxic, with lots of gut and adrenal problems. I am in the process of pursuing "extreme mold avoidance" and leaving my belongings behind and living in a trailer. I am 100% convinced that mercury is behind my POIS. For about 7 days after orgasm I have a major increase in my symptoms associated with mercury toxicity. Depression, fatigue, apathy, weakness, dizzyness, light headedness, sense of doom, etc. This starts to improve around day 7 and continues to improve for a few days after that.

I need to get back to chelating as that was the only thing that really helped. Using the Cutler protocol. But as of now, this mold issue is pressing. There's lots of stories of people exposed to minute amounts of mold that would not bother certain people, but those who are very sensitive to it get whacked by it and have all sorts of symptoms similar to the ones we describe here. I am pursuing the mold theory as of now.

OMG, we share IDENTICAL story except mold. (Removed amalgam 1 year a go). I remember that after orgasm 3 years a go i had 4-5 weeks of anxiety and depression, derealization, obsessive compulsive thoughts, irritable, angry, unsocial and omg sense of doom, what a fucked up insane feeling. I started to think about suicide to end that shit. It was nasty. Now i feel better 70-80%. I did only 27 round of chelation but that not helped as enema.

Maybe you tried but please do try oregano oil + grapefruit seed extract enema, that enema was life changing for me, i got really better, it's like i temporary removed fat mucus  or some candida from colon, and oregano oil is preventing probably candida to spread again. I was doing enema daily for a year at afternoons and that enemas eliminated almost all of my problems, especially food cravings. After syllimarin and artichoke pills i'm not doing enemas anymore, but i must be careful with diary because of lactic acid, less diary i eat i feel better.

You probably know this but also try bile salts to speed up mercury extraction from liver and to properly absorb omega 3 and a,k,d,e vitamins. Fatty mercury livers are not producing enough bile. All the best.

https://www.facebook.com/notes/andy-cutler-chelation-safe-mercury-and-heavy-metal-detox/-liver/1196821223749614/?_rdc=2&_rdr
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Iwillbeatthis on January 04, 2021, 08:18:16 AM

I saw a box of liver detox pills with artichoke, milk thistle , dandelion on clearance so I bought them after seeing your post. It improves my stools a lot while I'm taking but I haven't seen much improvements with brain fog etc. I remember when I took just milk thistle in the past it was also similar.

Four years ago when I had CT scan it showed I had gall bladder stones but they were non invasive maybe that could be affecting my bile production in the gall bladder.

Well, healing liver if you have fatty liver does not come overnight, when i discovered syllimarin and artichoke pills i eat just one, and i sensed that in some moments my mind feel sharp, then i increased the dosage to two in the morning and 1  at 15h and 1 before sleep. I tried every vitamin suplement in existence. Minerals,zinc, copper, and nothing helped like artichoke and syllmarin, i feel even better if i avoid dairy and processed food, so try to avoid that for a week.

Did you test for fatty liver? Fatty liver does not produce enough bile.

Regarding gallstones. It can block or reduce bile flow. Pills you say you eat is the best for your liver and can only help you, can not do any harm, so that's positive :). I found 10 things on youtube that is helping liver, and i tried dandelion but did not feel better with dandelion. And some guy on youtube said that dandelion helped him. So it's all trial and error but with sylimarin and artichoke we can not miss. Those two ingredients are on the top of pyramid.

https://www.nhs.uk/conditions/gallstones/complications/

All the best.

I haven't been tested for fatty liver but in the past my liver function test was normal, I have none of the symptoms of fatty liver disease anyway, I think my kidneys are the ones that aren't working well compared to my liver, I get pain sometimes in the flanks and my creatine levels are at the highest range value
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: drop247 on January 04, 2021, 12:23:31 PM
i discovered syllimarin and artichoke pills i eat just one, and i sensed that in some moments my mind feel sharp,

I just trialed a supplement with combined  Sylimarin, Artichoke, and Tumeric. Like you I had almost immediate effect. I don't think it could be acting on the liver this quickly. Perhaps it is acting on neurotransmitters? It does feel good. My body felt lighter, less inflamed, and my sinuses opened up. I've read Sylimarin is a mast cell stabilizer.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Muon on January 04, 2021, 12:44:14 PM
Quote from: drop247
I've read Sylimarin is a mast cell stabilizer.
Bingo https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.12138

And about the mental sharpness; MCs communicate with glial cells.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Igy78 on January 04, 2021, 02:36:22 PM
i discovered syllimarin and artichoke pills i eat just one, and i sensed that in some moments my mind feel sharp,

I just trialed a supplement with combined  Sylimarin, Artichoke, and Tumeric. Like you I had almost immediate effect. I don't think it could be acting on the liver this quickly. Perhaps it is acting on neurotransmitters? It does feel good. My body felt lighter, less inflamed, and my sinuses opened up. I've read Sylimarin is a mast cell stabilizer.

I have that effect after 45 minutes to an hour, and it last for about 5-6 hours, i'm more on theory that those pills is helping liver to remove/filter toxins (probably even histamine or lactic acid) from blood "quickly" because i did not take sylimarin and artichoke for 4 days and instead of that i'm taking ox bile for 4 days, and it's almost the same effect but i must be more careful with diary/lactic acid.

Regarding mast cell, maybe it's like Muon already said that liver is producing HNMT enzymes for break down of histamine."Curcumin/Turmeric was reported to have anti allergic properties with inhibitory effect on histamine release from mast cells." So maybe those pills and bile salts are kick starting production of that enzyme. Whatever those pills do i'm glad that i'm feeling better.

I am so glad that you also find relief with those pills, will also try curcuma.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: nebraska on January 05, 2021, 12:03:08 AM
I can say that I have a very similar problem as Igy. My POIS is definitely directly related to the gallbladder, its condition and bile acids, but I still cannot fully understand how.

According to the analysis of my shit, I have a little indigestion of fats and according to the ultrasound of the gallbladder, I have a polyp of unknown genesis there (in the area of ​​the biliary neck), I was diagnosed with biliary hypotension.

On the Russian forum there are 2-3 people who have cured their pois by curing the gallbladder (2 people vigorously drove bile, and 1, on the contrary, chose a diet so as not to disturb the gallbladder as much as possible).

I have digestive problems such as
-large gases
- going to the toilet every 3-4 days

and any drugs that at least somehow touch the gallbladder in a special way affect the POIS
-Artishok 30 minutes before meals definitely does better
-If I add milk thistle, my autistic symptoms seem to increase
-If I start adding a handful of nuts 30 minutes before a meal, my stool improves sharply, one day it becomes much better than my illness, sociality improves, brain fog improves, but after 48 hours it gets worse
- if I do not add chips, milk, any unhealthy food to my food - I feel better
- if I drink drugs that relax the muscles of the gallbladder (hymecromone), my POIS becomes much worse and the digestive symptoms intensify, the right side begins to hurt

I also tried a gentle diet for gall, it got a little better, and then immediately a little worse.
If I stop eating foods that stimulate the gall completely, I get worse.


In general, I cannot say what exactly is wrong with my gall and how it affects the POIS, but this is directly related
Apparently, somehow the lack of bile acids kills the intestines.

In general, reading this forum for several years, most of the cure stories are related to the effect on the intestines. That is, there are many conditions that affect the gut and cause POIS. SIBO, MCAS, food allergies, bile problems, acid problems, etc.

I can say that over the course of a year I established a lot of correlations with my gut, a month I ate apples and chicken, then just chicken, food with low histamine, food with low FODMAP, food with low lectins, and I can say with certainty what the condition gallbladder correlates with my POIS.
I'm a little bit stumped because I don't know what to experiment with next. Obviously, I have hypotension and I need to stimulate the flow of bile, but the power of the artichoke is not enough for me, it gets worse on milk thistle, from nuts before eating too, that is, most likely, my intestines cannot withstand pure fatty foods, then how can I to stimulate my gallbladder to test further?

I also tried bile acids, but it seemed to me that it got worse and I stopped the experiment, apparently, I need to carry it out again.

If it is still clear why nuts before meals make it worse (indigestion of fats), but why stimulation with pure bile acids and milk thistle makes it worse, it is completely incomprehensible. Maybe I have an inflamed gallbladder and any injury to it makes it worse, but why then didn't a gentle diet make me better?


And what could be a polyp?

Thanks for reading, good luck everyone.

P.S. I have a polyp of the gallbladder near the duct and on a broad base, but 3 years ago I did not have a polyp, there was a bend of the gallbladder in the same place where the polyp + hypotension, but there was a POIS.
But POIS got worse during this time.

My pois is getting MUCH worse if i smoking right quickly after inhaling(cigarette or e-cig, doesnot matter)
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Igy78 on January 05, 2021, 09:03:56 PM
Little feedback about OX bile/ bile salts, i was on low dosage and i was ok, but unfortunately when i increased dosage it tend to lower stomach acid and last day i feel like shit, so be careful with dosage, i took 500 mg in the morning and at noon and at evening. I stopped taking it due to undigested food reaching intestines. Some symptoms got back. I started to take again syllimarin and artichoke to feel better. Too bad that bile salts lowers stomach acid. I probably could fix that by taking betain hcl pills but than it's too expensive to eat all that. Well, it was a unsuccessful try without syllimarin and artichoke. Now i'm scared to try even smaller dosage of bile salts like i did at start. Probably lower dosage works best but i was more sensitive to food. So i will stick for now with syllimarin and artichoke, almost insta relief.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Igy78 on January 05, 2021, 10:10:00 PM
/cut

Did you go for Gastroscopy? I am seriously thinking to do that, it's a little weird that syllimarin and artichoke work so fast so i'm suspecting for some bacteria in stomach, i did test for h. pylori, stool test, breath test and test was negative, but it's really weird for me to have relief so fast.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: nebraska on January 06, 2021, 01:08:42 AM
Yes, I did a gastroscopy, but I did it during a routine examination in a free clinic (in Russia this is a very low-quality level of medicine). There I was diagnosed with non-serious gastritis and did not find serious violations, but, it seems, the gastroscope did not go beyond the stomach. I want to undergo a full examination by a gastroenterologist in a private clinic and do high-quality gastroscopy and other various examinations of the intestine, gallbladder, etc.

By the way, I remembered that about a year ago, my symptoms improved by about 10 days while taking Metranidazole.
This may indicate both the death of parasites in the gallbladder and an improvement in the flow of bile, and a temporary improvement in SIBO, but since then I have done everything to remove the alleged SIBO, but nothing helped me.

p.s. Also, I've heard of SIBO caused by lack of bile.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: aswinpras06 on January 06, 2021, 04:33:07 AM
Bile salt pills taken after meals did not prevent the malabsorption.  I took them for 4 meals and found no difference.  I will try for another three days and stop if same thing happens.

Dear Igy78

Please tell me whether Silimarin and artichoke to be taken before meals or after meals for best results.    Many of the digestive enzymes work better when taken before eating a meal.  Is it the same for artichoke and silimarin?
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: drop247 on January 06, 2021, 04:42:01 PM
It really does act fast. I'm in the beginning of POIS and it knocked down my headache and sinus inflammation in under 5 minutes. Faster than regular antihistamines. It seems to work better than quercetin. Maybe I should be taking Milk Thistle everyday since I never really get out of POIS anymore.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Muon on January 06, 2021, 04:51:30 PM
"It has been reported that silymarin inhibits cytochrome P450 enzymes..." https://en.wikipedia.org/wiki/Silibinin

"iron chelating and antioxidant properties"---->ROS?
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Igy78 on January 06, 2021, 07:30:41 PM
Bile salt pills taken after meals did not prevent the malabsorption.  I took them for 4 meals and found no difference.  I will try for another three days and stop if same thing happens.

Dear Igy78

Please tell me whether Silimarin and artichoke to be taken before meals or after meals for best results.    Many of the digestive enzymes work better when taken before eating a meal.  Is it the same for artichoke and silimarin?

2 pills in the morning, 1 at noon and 1 at evening. That's sweet spot for me. I take extra pill when i start to feel little symptoms.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: quikot on January 08, 2021, 10:23:03 AM
I've been experimenting with Artichoke and Milk Thisle recently. Some positive effects are: jaundice disappeared, more alert, quieter tinnitus, improved eye photosensitivity, face looks more alive.

However, got one bad side effect: almost constant chest pain. Could it be that I have gallstones which obstruct increased bile production, causing me chest pain? Stopped taking these two supplements for now. I will have an ultrasound scan later this month to see if I have gallstones or any other liver problems. Insufficient flow of bile can lead to SIBO, which could lead to POIS, in theory.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: aswinpras06 on January 08, 2021, 11:21:02 PM
I've been experimenting with Artichoke and Milk Thisle recently. Some positive effects are: jaundice disappeared, more alert, quieter tinnitus, improved eye photosensitivity, face looks more alive.

However, got one bad side effect: almost constant chest pain. Could it be that I have gallstones which obstruct increased bile production, causing me chest pain? Stopped taking these two supplements for now. I will have an ultrasound scan later this month to see if I have gallstones or any other liver problems. Insufficient flow of bile can lead to SIBO, which could lead to POIS, in theory.

Do you have any asthma or allergic rhinitis.  Artichoke is known to trigger or worsen asthma problem.  That may be the reason for your chest pain.  But please check with your doctor for gallstones.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: quikot on January 09, 2021, 03:52:49 AM
Do you have any asthma or allergic rhinitis.  Artichoke is known to trigger or worsen asthma problem.  That may be the reason for your chest pain.  But please check with your doctor for gallstones.

Well this is an unlikely case for me as I don't have asthma or any allergies at all except hay-fever. But it's good that you pointed this out for other users.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Muon on January 16, 2021, 12:32:31 AM
Quote from: drop247
I've read Sylimarin is a mast cell stabilizer.
Bingo https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.12138

And about the mental sharpness; MCs communicate with glial cells.

Mast Cells Promote Non?Alcoholic Fatty Liver Disease Phenotypes and Microvesicular Steatosis in Mice Fed Western Diet (https://aasldpubs.onlinelibrary.wiley.com/doi/abs/10.1002/hep.31713)
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Investigator on January 16, 2021, 07:18:36 AM
I had an ultrasound exam and the doctor said the liver is OK, nothing about fatty liver. Still, it is true that I felt better when I tried silymarin a couple of months ago. 
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: aswinpras06 on January 17, 2021, 12:20:09 AM
It really does act fast. I'm in the beginning of POIS and it knocked down my headache and sinus inflammation in under 5 minutes. Faster than regular antihistamines. It seems to work better than quercetin. Maybe I should be taking Milk Thistle everyday since I never really get out of POIS anymore.

Hi Drop247

How much milk thistle did you take 250mg or 500.  Whether with food or on empty stomach.  I currently take 250mg milk thistle before each meal.  I also have severe sinus problems.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: drop247 on January 17, 2021, 07:30:50 AM
Milk Thistle Seed Standardized 80% Extract (Silybum marianum L.) 250 mg (Providing 200 mg of Silymarin) with a meal.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Igy78 on January 22, 2021, 09:00:56 AM
Hi guys, little feedback, i did gastroscopy/endoscopy and not a great news, doctor found hiatus hernia, gerd, erosive Gastritis and Duodenitis, so no wonder i was food intolerant, what is funny i reacted to exactly same kinds of foods which is forbidden on a diet for erosive gastritis/gerd/duodenitis. No cold cuts, no diary, no mayo, no butter, no bacon, no vinegar and so on. I am reacting to those foods with POIS symptoms, after orgasm even more. I make it worse by smoking cigarette and vaping e cig. Anyway i did found great relief with syllimarin and artichoke pill, that pills are reducing inflammation so i started to feel better not knowing that pills are actually reducing inflammation on mentioned problems in stomach. At first i started taking it for the liver. Finally some luck  :). Symptoms dropped by 70-80%. And i can eat "forbidden" foods bit by bit in smaller quantities, where before even when i just look at those food i got POIS symptoms. And also when i fast for 24+ hours i feel great. So problem was in my stomach all the time, amazing how stupid i was with my theories  ;D. Probably mercury have fingers in all that. Doctor prescribed antacid so i can slowly heal all my problems. I almost forgot that sleeping on a belly in a upright position with elevated body was a lifechanger for me. Probably less acid goes to esophagus that way while sleeping or less gerd i have. I did biopsy for h.pylory and will found out in a few days. Will give another feedback in a few weeks. All the best.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: drop247 on January 22, 2021, 09:44:18 PM
Thanks for the update. Fasting also helps me a lot whether it be single 24-36 hour fasts or daily 16 hour intermittent fasting. Did the doctor give any indication of what might be causing the damage to your GI tract besides H. Pylori? Histamine controls gastric acid secretion. I also seem to have GI injury in the form of silent reflux (LPR) that damages my throat, and even hurts my sinuses, tongue, and inner ear. I also have intestinal pain that I assume is gastritis from either excess acid or food sensitivities. I saw you were taking Betaine HCL, that really hurts my intestine worse than anything.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Igy78 on January 23, 2021, 06:07:38 AM
Thanks for the update. Fasting also helps me a lot whether it be single 24-36 hour fasts or daily 16 hour intermittent fasting. Did the doctor give any indication of what might be causing the damage to your GI tract besides H. Pylori? Histamine controls gastric acid secretion. I also seem to have GI injury in the form of silent reflux (LPR) that damages my throat, and even hurts my sinuses, tongue, and inner ear. I also have intestinal pain that I assume is gastritis from either excess acid or food sensitivities. I saw you were taking Betaine HCL, that really hurts my intestine worse than anything.

I told my doctor that i am taking betain hcl pills and i feel better, and he said that i will never heal because keeping constant normal acid in stomach can not heal problems that i have. To heal i must now lower stomach acid for a period of time. I will consume that antacid pill for 4 weeks every day. He said that he does not recommend betain hcl pills, i asked him but why i feel better on betain pills he said that he does not know. And that i can do even more damage with that problems that i have. Very weird situation where i feel better from betain pills but i can do more damage.

 I did stopped with betain hcl pills 2 weeks a go to test to see can syllimarin/artichoke pills replace betain and i did feel good and i think i can go without betain pils. Doctor said that i must avoid soda, cola, fanta, sprite, especially artificial sweeteners like aspartam (Orbit chewing gum) and so on. I should avoid also, fatty/greasy food, diary. Also need to avoid foods that require stronger stomach acid. I did consume all those thing from when i was 14-15 y old in huge quantities, especially cola, fanta, sprite, so all that damaged my gi tract over the years. I did not eat any vegetable, only pommes frites and hot dogs and pizzas. I did have little symptoms back then in young days but i thought then that it's nothing serious until 3 years ago when i started vaping like a madman. Doctor also said that i need to avoid cigarettes and e cigs, luckily i stopped that 2 years ago.

I also remember that i started 3 years a go to drink 4-6 liters od sprite with aspartam every day for a month and started to feel stronger symptoms, food intolerance showed up, low self confidence/ esteem, suicidal thoughts, sense of doom, remembering bad/cringe/shame situations in life. Everyone hates me and feelings like that. So soda/aspartam surely inflamed my intestines. I did feel worse with cola zero than regular sugary cola. Symptoms always got worse after sex/or fapping and lasted for weeks. Now it's different story, not drinking all that drinks anymore, stopped with junk food long time a go. Probably syllimarin/artichoke has speed up healing of GI tract.  Maybe it lowers acid stomach, can not be sure on that.

Yesterday i tried very little amount of mayo and milder symptoms came back after 30-40 minutes of eating mayo until i digested that mayo for a few hours. It's a amount of time needed for food to get to the beginning of the small intestine, and i got there inflamation (Duodentitis). It was very tolerable. Before symptoms lasted for a week if i did eat "forbidden" food for my gastrointestinal problems. So i think i can find myself cured when i can eat vinegar , mayo and bacon without any symptoms or when food intolerance stop completely.

When you say that fasting helps you i think you surely have some inflamation. Because there is no contact of food with intestines and there are no POIS symptoms. Almost identical as my case.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: aswinpras06 on January 23, 2021, 08:01:10 AM
Dear Igy78

Even I had gastritis and Helicobacter infection when I had endoscopy few years back.  The antacid and antibiotics never worked and my gastroenterologist ordered colonoscopy and some other tests but could not find out what is the cause of my chronic digestion problems and asked me to do further advanced tests which I declined.  I regret not following up with my gastrodoctor because some thing might have been known about our disease if I have done them.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: drop247 on January 23, 2021, 08:55:53 AM
I'm the same way. Betaine HCL or even just Apple Cider Vinegar makes my digestion incredible and makes me feel energized and great. Perfectly formed no wipe stools. Unfortunately it absolutely destroys the tissues of my GI tract which can't seem to tolerate the increased acid at all.

I've always been sensitive to acid. My entire family can't handle acidic foods like tomatoes or pineapples or we get terrible canker sores in our mouths.

I've experimented with digestive enzymes that don't contain Bromelain, which are harder to find but do exist. Anything with Bromelain (enzyme from Pineapples) will start eroding the tissues of my throat due to my silent reflux bringing the enzyme back up into my esophagus and it digesting my tissues like it would any other meat.

I don't think digestive enzymes are the answer though and will instead now try to increase my bile production, like you, or I will try to change my microbiome with increased prebiotic fiber and perhaps temporary probiotics supplements and fermented foods. Though I'm concerned about the histamine content of fermented foods since histamine seems involved in my POIS.

Do you have loose light colored, yellowish, or otherwise not brown stools? I do and am trying to investigate what that indicates. I also have a lot of undigested food in my stools.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Journey on January 23, 2021, 03:37:13 PM
I'm the same way. Betaine HCL or even just Apple Cider Vinegar makes my digestion incredible and makes me feel energized and great. Perfectly formed no wipe stools. Unfortunately it absolutely destroys the tissues of my GI tract which can't seem to tolerate the increased acid at all.

I've always been sensitive to acid. My entire family can't handle acidic foods like tomatoes or pineapples or we get terrible canker sores in our mouths.

I've experimented with digestive enzymes that don't contain Bromelain, which are harder to find but do exist. Anything with Bromelain (enzyme from Pineapples) will start eroding the tissues of my throat due to my silent reflux bringing the enzyme back up into my esophagus and it digesting my tissues like it would any other meat.

I don't think digestive enzymes are the answer though and will instead now try to increase my bile production, like you, or I will try to change my microbiome with increased prebiotic fiber and perhaps temporary probiotics supplements and fermented foods. Though I'm concerned about the histamine content of fermented foods since histamine seems involved in my POIS.

Do you have loose light colored, yellowish, or otherwise not brown stools? I do and am trying to investigate what that indicates. I also have a lot of undigested food in my stools.
I often have yellowish stools
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Investigator on January 24, 2021, 04:44:05 AM
Thanks for the update, Igy78, your input is really helpful. It's good you got specific problems diagnosed and know how to approach them.

I've had stomach issues for a long time, but I never associated them with POIS, since 1) I had them long before my POIS started, and 2) many people have stomach issues, can't tolerate acid foods, etc. What is interesting, though, is that 2 weeks before my POIS started, I had acute stomach problems, diarrhea and vomiting, as a result from eating eggs that had gone bad. Maybe those spoiled eggs added something to contribute to my microbiome? Who knows what was in them. I used to drink cola but have quit it completely about 20 years ago (with POIS starting about 4 years ago).

I have problems with acid food, like tomatoes - my belly inflates, gets filled with some sort of gas and I feel some type of expansion from the inside taking place. This disappears if I lay on my back for some time, and I've had it long before POIS, that's why I've always thought of it as an unrelated and more minor problem. 

An interesting observation: there is a certain NSAID, dexofen (active ingredient is dexketoprofen), which, despite being anti-inflammatory, on its own seems to activate my POIS! Well, it causes stomach disturbance (any time I take it) + activation of POIS (most of the time). What do you think? On the one hand, NSAID's should have positive effect on our POIS. But here, even days after orgasm, this triggers POIS if I take it. Maybe it irritates the stomach and that in turn brings about POIS symptoms? What irritates the stomach need not be the active ingredient, but one of the minor ingredients. That would be consistent with some kind of "gut-induced" theory for POIS

Can anyone propose a possible connection between ejaculation and activation of gut inflammation? I don't know enough internal medicine to imagine how the two would be related.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: aswinpras06 on January 24, 2021, 05:02:28 AM
Hi Investigator

Mast cells.  This is the most likely connection and could be the exact reason.  Mast cell activation disorder is likely the cause of all our miseries.  But the method to stop this is a very difficult because each of us are unique and only through trial and error we can find out what works for us.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Journey on January 24, 2021, 05:45:31 AM
Hi Investigator

Mast cells.  This is the most likely connection and could be the exact reason.  Mast cell activation disorder is likely the cause of all our miseries.  But the method to stop this is a very difficult because each of us are unique and only through trial and error we can find out what works for us.
What could have induced the mast cell activation disorder in the first place and what would be the long term treatment for that which would ensure they never degranulate and cause all of those symptoms?
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: aswinpras06 on January 24, 2021, 07:48:51 AM
Hi Investigator

Mast cells.  This is the most likely connection and could be the exact reason.  Mast cell activation disorder is likely the cause of all our miseries.  But the method to stop this is a very difficult because each of us are unique and only through trial and error we can find out what works for us.
What could have induced the mast cell activation disorder in the first place and what would be the long term treatment for that which would ensure they never degranulate and cause all of those symptoms?

Most likely cause is a genetic defect.  But still by changing our diet and lifestyle we can prevent this abnormal activation to a certain extent.  I have not been able to do that because of my very late discovery about this.   An allergist/immunologist will be the best one in main stream medicine who can advice us for mast cell issues. 
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Igy78 on January 24, 2021, 01:28:40 PM
@investigator

Last year i took paracetamol for high temperature in inflamed colon, i got really ultra strong POIS symptoms lasting for a week, with vitamin c also, so i put salt on open wound. Until inflammation is gone i will have POIS symptoms. Best way to see if GI tract is inflamed is gastroscopy/endoscopy, and also fasting for 24/48+ hours + syllimarin and artichoke. If you feel better while fasting that's it, GI tract is inflamed.

I also found this

"Severe illness and prolonged use of medications such as nonsteroidal anti-inflammatory drugs (NSAIDs), alcohol, or tobacco may also lead to duodenitis".
"When NSAIDs irritate the gastric mucosa, they weaken the resistance to acid, causing gastritis, ulcers, bleeding, or perforation. The damage ranges from superficial injury to single or multiple ulcers, some of which may bleed"


Regarding mast cells, probably inflammation activates mast cells where some food causing the inflammation.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: quikot on January 25, 2021, 03:48:44 PM
Interesting, recent blood test shows I have 12 nmol/l of Mercury in me. And it says 'normal' range is less than 15. 12 is pretty damn close to 15 in my opinion.

Well then... I'm most likely going to extract and replace all my 8 or so amalgam fillings and then start chelation.

Has anyone here done a blood test to check for mercury levels soon after amalgam removal? Was it elevated or lower? I'm a bit afraid that I might expose myself to overwhelming levels of mercury....
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Clues on January 26, 2021, 02:42:10 AM
Interesting, recent blood test shows I have 12 nmol/l of Mercury in me. And it says 'normal' range is less than 15. 12 is pretty damn close to 15 in my opinion.

Well then... I'm most likely going to extract and replace all my 8 or so amalgam fillings and then start chelation.

Has anyone here done a blood test to check for mercury levels soon after amalgam removal? Was it elevated or lower? I'm a bit afraid that I might expose myself to overwhelming levels of mercury....

Just contributing with my 2 cents. If you want to remove them, please make sure to go to a dentist that takes mercury toxicity seriously. The dentist I went to used a rubber dam -- an elastic rubber sheet with a hole in it for the tooth, that hugs the base of the tooth very tightly -- so no liquid or particles flow into your mouth. Also she used a breathing device over my nose so I wouldn't breathe in any particles or fumes. Another precaution was that they tried to remove the fillings in larger chunks, rather than breaking them down too much or melting them and potentially releasing particles or fumes.

Also, there is some scientific evidence to suggest chlorella supplementation can help remove mercury from your body. I'd look into it and consider supplementing after (maybe right before also?) you remove the fillings.

FWIW I suspect a mercury issue in my case as well, and I've had symptom improvements with chlorella supplementation over the last half a year or so.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: quikot on January 26, 2021, 11:38:00 AM
Also, there is some scientific evidence to suggest chlorella supplementation can help remove mercury from your body. I'd look into it and consider supplementing after (maybe right before also?) you remove the fillings.

Chlorella sounds promising indeed, so I'll read up on it. I was thinking of doing the Andy Cutler Chelation since many people on Internet say it helped them detox.

Btw, how many amalgam fillings did you have? Did they replace all at the same? Is removal of multiple amalgams safe in one go?

I found a biological dentist here in the UK, he's SMART/IAOMT certified and has years of experience, so I'll book my first consultation as soon as my finances get sorted.

I still remember my worst ever POIS episode was after I ate steamed Salmon. On top of my regular POIS symptoms (like fatigue, chest pains, back pain, tinnitus) I got horrible photosensitivity, eye floaters, louder tinnitus and all my fingertips felt like they were burning, I felt nauseated and almost felt like I could die. Soon after this episode I took a blood test and my Neutrophyl count seriously decreased. Maybe mercury from seafood exacerbated already high mercury levels in me. Few months later I ate steamed Salmon again, as an experiment, and got a similar experience.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Clues on January 26, 2021, 01:57:23 PM
AFAIK there is no comprehensively researched, scientifically proven mercury removal method. I've seen various protocols, but I think you'll find unfortunately that different dentists have very different attitudes and knowledge around this, so it's hard to know whom to believe.

Personally, I removed my biggest fillings (3 or 4 I think) about 10 years ago with a dentist who used a dam, but otherwise did not take the issue seriously and did a poor job. Suspect I got a lot of mercury in me from that.

I thought I'd removed all my fillings but to my horror found some months ago I still had 4 (I think) smaller amalgam fillings left. I did some more research this time and went to the dentist I mentioned in the previous comment who took some serious precautions. That dentist said that if I'd had bigger fillings, or more of them, she'd have recommended multiple sessions, but since I only had a few small ones she recommended I take them all in one go, which I did. I had no change in symptoms after taking them out. I was supplementing with chlorella at the time.

Btw, in my personal unscientific opinion, the salmon thing sounds like it may have been something else, as the amount of mercury in a single fish should be minuscule, even if you're sensitive to mercury. Histamine content maybe?

I wish you the best of luck! Be careful out there.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: berlin1984 on January 26, 2021, 02:41:27 PM
I have gum problems, but didn't have much caries in my life, don't have any fillings except for cosmetic reasons.

So the thing I'm wondering: As POISers, are we more likely to have chronic infections or disbyosis? gut, mouth, wherever. Bacteria, viral, parasites, whatever?

(Theory still goes like: natural body functions going on in arousal or orgasm make infections worse, things like heavy metals make it worse too, genetics have an effect too obviously..)

I more and more believe that it's futile to find a single root cause, it's all a holistic combination... a more eastern medicine view on things.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Iwillbeatthis on January 26, 2021, 04:33:53 PM
For me it is 100% a chronic infection of some sort I think either fungal/mold or viral but I think disbyosis has also happened as a result of the chronic infection.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: quikot on January 26, 2021, 04:41:57 PM
Personally, I removed my biggest fillings (3 or 4 I think) about 10 years ago with a dentist who used a dam, but otherwise did not take the issue seriously and did a poor job. Suspect I got a lot of mercury in me from that.

I've read similar stories like this one, people wanting to detox from mercury would go to a dentist who would do a poor job at amalgam removal, resulting in long-term deterioration of patient's health. Scary.

So I will be vigilant and insist on maximum precision and safety. My health is already quite fragile, so obsessive precautions are a must.

As for the salmon thing, you might be right. Or maybe I got food poisoning from undercooking in steam? I'd have to get food poisoning again to know for sure. I know I didn't react so badly to a deep fried salmon. And I can tolerate tuna and alaskan pollock quite well. Weird.

Anyway thank you Clues. Good luck to you too!

I more and more believe that it's futile to find a single root cause, it's all a holistic combination... a more eastern medicine view on things.

I also think that approaching my illness from a holistic perspective makes sense. Certainly for me, when symptoms affect so many parts and functions of my body, I don't really know what to focus on except the whole.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: JohnJames on January 27, 2021, 07:01:21 AM
I haven't been keeping up with this thread since I've been busy.

Skim reading through I want to reiterate this point: Alpha Lipoic Acid is the ONLY chelator we know that can pass the blood brain barrier, remove mercury, is available as a supplement, and we know how to dose effectively.

Many other substance may tick a few of those criteria, but none other ticks all of them. You will never be 100% better unless you remove the mercury in the fatty tissues of your brain if mercury is the culprit.

I have gum problems, but didn't have much caries in my life, don't have any fillings except for cosmetic reasons.

So the thing I'm wondering: As POISers, are we more likely to have chronic infections or disbyosis? gut, mouth, wherever. Bacteria, viral, parasites, whatever?

(Theory still goes like: natural body functions going on in arousal or orgasm make infections worse, things like heavy metals make it worse too, genetics have an effect too obviously..)

I more and more believe that it's futile to find a single root cause, it's all a holistic combination... a more eastern medicine view on things.

You don't need amalgams to have picked up mercury - controversial subject but many va((ines historically contained thimerasol, a preservative which contained mercury, many reactions to va((ines are consistant with mercury poisoning. FYI I'm not a conspiracy nut or anything, va((ines do work, and thimerasol is used much less in modern ones, the damage that widespread disease could cause is probably far worse than a few people becoming mercury toxic.

Mercury toxicity can pass from mother to child due to it being lipophillic.

Mercury is present but not limited to: fluorescent bulbs, thermometers, fatty fish, even being in a dentists office can expose you. Ever been around a shattered fluorescent bulb? You've been exposed, especially if it was not cleaned up to proper protocol. Has your mother ever been exposed in any of these ways? Does she have any "issues"?

I think there are different types of POIS but for each individual it stems from one cause that causes a cascade of symptoms. e.g for those whom cure it with some diet or supplement, why must they take the supplement to be POIS-free but a healthy individual is POIS-free anyway?
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Igy78 on January 29, 2021, 10:28:06 AM
Hi guys, little feedback, i did biopsy of sample from stomach week a go when i did gastroscopy where they found gerd, duodenitis, erosive gastritis which is manifested by bleeding. Today came results from biopsy.

"Two pieces of gastric antrum mucosa were received. The integumentary epithelium is neat, the fovea converge towards one end (erosion) and the glands are of adequate thickness. In the lamina propria above the glands are scarce lymphocyte infiltrates and slightly smaller foci of bleeding. H.pylori is negative. DG. GASTRITIS CHRONICA EROSIVA"

So,..  my whole body is inflamed due to open wounds in stomach due to lack of gastric mucosa, my body is constantly fighting bacteria, pathogens and undigested food due to open wounds. Consuming cold cuts, bacon, diary, vinegar are making my POIS symptoms stronger and intolerable. Probably my body is telling me that way that i must avoid that kind of foods if i want to heal stomach.  That's why i have psoriasis and POIS after sex/fapping.

I did a week of antacid and symptoms came back a little, little bit of POIS feelings/symptoms as before betain pills so that is proof that i had low stomach acid before or gastric mucosa cells are malfunctioning. Why in the hell i am feeling great because of betain pills, but lowering stomach acid with antacid is making feel like shit. So i will stop with antacid pills. Could it be that betain pills making stomach acid stronger and cells which provide gastric mucus detect high stomach acid and produce more mucus which protect stomach. Or maybe stomach acid was fine all the time just cells which provide mucus are malfunctioning. I'm taking again betain pills and i started to feel better.

Is it possible that the body wants to cure gastritis by lowering stomach acid and then i got chain of problems, POIS, undigested food goes to duodenum and making inflammation there (duodenitis). Could it be that syllimarin and artichoke making some protective film arround stomach so that's why i feel great after consuming that. . Gonna stick with strict diet, fasting and syllimarin and artichokes. 

Still not doing rounds of chelating from mercury. I stopped at round 27 where i did not see major improvements. I strongly recommend gastroscopy/endoscopy because it could take years after chelating and even then you could not feel better while problems could be in your stomach/gut. I did 27 rounds/weeks of chelating, that is almost 7 months of chelating where i did not feel better. Will report soon. All the best.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: quikot on February 03, 2021, 04:06:35 PM
So where do I buy the ACC chelators from? Is livingsupplements.com OK to buy from? Also, is DMPS safer than DMSA? I've read that DMSA may cause neutropenia, which I should probably avoid because my neutrophil count is already low. But I've also read about that one case where DMPS triggered the Steven Johnsons Syndrome in a child.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: berlin1984 on February 06, 2021, 05:18:07 PM
Could it be that syllimarin and artichoke making some protective film arround stomach so that's why i feel great after consuming that. . Gonna stick with strict diet, fasting and syllimarin and artichokes. 

Could it be the Luteolin (https://poiscenter.com/forums/index.php?topic=384.msg39161#msg39161) in Artichoke extract and the Silymarin in Milk Thistle (https://poiscenter.com/forums/index.php?topic=2372.msg19856#msg19856) that stabilizes your mast cells?
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Muon on February 06, 2021, 05:43:00 PM
I wouldn't be surprised when his Lymphocyte infiltrates are actually mast cells.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Hopeoneday on March 01, 2021, 10:43:00 AM
(https://i.redd.it/lsdl429cz8j61.png)

Exemple of poiser with low glutathione vitamins and nutrients...https://poiscenter.com/forums/index.php?topic=2684.msg39545#msg39545

Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Hopeoneday on March 01, 2021, 10:51:16 AM
I noticed that many poisers reported somthing similar to CACHEXIA.
https://en.wikipedia.org/wiki/Cachexia
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Hopeoneday on March 01, 2021, 03:48:47 PM
A wery nice study, BIODETOX etc....

https://ehjournal.biomedcentral.com/articles/10.1186/1476-069X-13-95#Tab3

Table 3 One year odds of symptom improvement and
worsening in the treatment group from this study:
https://ehjournal.biomedcentral.com/articles/10.1186/1476-069X-13-95/tables/3

Significant improvement attributable to the amalgam removal treatment was seen for memory loss and stomach problems. Significantly less deterioration was seen for confusion, stomach problems, loss of sense of smell or taste, shakiness in hands, and coordination problems.


Me personaly think, that my SIBO is because of
toxicity of neuro motor copmlex-gut afected.
etc...



Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: BoneBroth on March 01, 2021, 05:12:35 PM
Yes, more and more is coming to this conclution here. It would be good to read how everyone who is trying the SIBO protocol are progressing. A thread for this perhaps?
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Hopeoneday on April 19, 2021, 02:21:57 PM
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC187773/
Most  recently,  a  study  on  monkeys  demonstrated  that  mercury  exposure  from  amalgam  might  enrich  the  intestinal  flora  with  mercury-resistant  bacterial  species,  which  in  turn  also  become  resistant to antibiotics ...



Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Hopeoneday on April 19, 2021, 02:50:19 PM
Apolipoprotein E genotyping as a potential biomarker for mercury neurotoxicity
https://pubmed.ncbi.nlm.nih.gov/12897404/


Genetic Aspects of Susceptibility to Mercury Toxicity: An Overview
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295343/
 
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Hopeoneday on July 10, 2021, 11:44:13 AM
https://herballure.com/HotTopics/MyMercuryStory.html

A meber Wayne links from CFS ME forum
https://forums.phoenixrising.me/threads/my-recovery-story.7912/page-13#post-2299565
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Igy78 on September 28, 2021, 01:12:00 PM
Did not give feedback for a long time, was in hospital in march for 4 days due to eating to much paprika in powder/spice, and i inflamed my pancreas, stomach and liver again. I was on endoscopy and long story short they found chronic erosive gastritis, acute pancreatitis and fatty liver,  was healing from march with gastritis diet and i feel better, here and there orgasms with improvement, but still had spikes of anxiety and depression, but only if i eat carbs. Well recently i cut out all of the carbs and i feel amazing, only when i'm really really hungry i eat bread but after 4-6 hours symptoms slowly coming back,  so carbs are obviously depleting some B vitamins, or pancreas has problems with amylase or liver can not replenish needed vitamins, or stomach is to sensitive for acidic foods, i am on ppi and i sense it , if my stomach is better i have more energy, here and there i fuck up with nutella and kinder bueno, one or two days feeling like shit but it passes. Anyway it will be long journey to heal all that without carbs. But i'm really glad that i am on right track and i do not wasting energy on searhing what is wrong with me and spending a lot of moeny for suplements that did not work. So if you did not visited a gastroenterologist or had an endoscopy my advice is to do all that.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: BoneBroth on September 28, 2021, 01:59:52 PM
Igy78: Where exactly was the endoscopy done, in the large intestine only? I also made an endoscopy there, but they said it look just fine. I think my problems are in the small intestine (SIBO), but they never look there.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: demografx on September 28, 2021, 02:27:22 PM
I had a diverticulitis attack that nearly killed me (inflammation of the intestines).
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: BoneBroth on September 28, 2021, 04:07:06 PM
I just met a guy on a fair last week who showed me before-and-after photograps on the large intestine after some months drinking something called "structured water" made by a machine from Japan. The results were amazing. The intestinal pockets that were showing on the before pictures were gone after some months on the water and the intestine looked like getting in to a young state again.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Igy78 on September 28, 2021, 04:32:08 PM
Igy78: Where exactly was the endoscopy done, in the large intestine only? I also made an endoscopy there, but they said it look just fine. I think my problems are in the small intestine (SIBO), but they never look there.

Endoscopy of the stomach, i also did 1 year before that endoscopy of intestines, everything was ok in colon, but in stomach was/is world war 3.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Hopeoneday on November 08, 2021, 04:14:18 PM
https://pubmed.ncbi.nlm.nih.gov/24898714/
Perspectives in endocrine toxicity of heavy metals--a review

Abstract
An attempt has been made to review the endocrine/hormonal implications of a few environmentally significant metals, viz, lead, mercury, cadmium, copper, arsenic and nickel, in man and animals. Special emphasis has been given to the adrenals, thyroid, testis, ovary and pancreas. Toxic metals can cause structural and functional changes in the adrenal glands. Their effects on steroidogenesis have been reviewed. It has been reported that thyroid hormone kinetics are affected by a number of metallic compounds. Occupational exposure to a few of these metals can cause testicular injury and sex hormone disturbances. Protective effects of a few antioxidants on their reproductive toxicity have also been discussed. Information gathered on female reproductive toxicity of heavy metals shows that exposure to these metals can lead to disturbances in reproductive performance in exposed subjects. Certain metals can cause injury to the endocrine pancreas. Exposure to them can cause diabetes mellitus and disturb insulin homeostasis. The need to develop molecular markers of endocrine toxicity of heavy metals has been suggested. Overall information described in this review is expected to be helpful in planning future studies on endocrine toxicity of heavy metals.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Hopeoneday on December 12, 2021, 05:47:41 PM
I wonder could one poiser be positive on antifibrilin antibodies?

Anti-Fibrillin-1 antibodies are available from several suppliers. In humans, this protein is encoded by the gene FBN1. The protein may also be known as MASS, ACMICD, ECTOL1, FBN, GPHYSD2, asprosin, and epididymis secretory sperm binding protein. The reported amino acid length is 2871 and the expected mass is 312.3 kDa.
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Hopeoneday on February 05, 2022, 04:46:29 PM
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403307/
Glutamate-mediated effects of caffeine and interferon-? on mercury-induced toxicity

(I think that this is the exact mechanism of
how coffe helping me)

Coffee consumption significantly reduced mercury-related toxicity. Of note, caffeine acting through adenosine receptors plays a prominent role in modulating glutamatergic input to various neurons (Fig. 1).

On the other hand, mercury-exposed rats have been shown to exhibit enhanced interferon-? (IFN-?) serum levels as compared to the controls (10). Furthermore, it is claimed that vascular endothelial growth factor and interleukin-6 (IL-6) are released from human mast cells via the stimulation of mercury and disrupt the blood-brain-barrier and permit brain inflammation

Mercury exposure is linked to a shift in the redox status toward oxidative stress. It may enhance lipid peroxidation in all tissues and may have deleterious effects on an organism (1). As MeHg easily crosses the blood-brain barrier, it is highly neurotoxic in exposed human populations (2). Therefore, its cytotoxic effect on neurons is stronger when compared to inorganic HgCl2, even at low levels (3). Eventually, MeHg administration reduces non-enzymatic and enzymatic antioxidants (6).

Mercury has been shown to affect several aspects of glutamatergic signaling (4). In this context, MeHg markedly increases the glutamate concentration at the synaptic cleft by enhancing spontaneous glutamate release from neurons (5). Eventual excitotoxic activity of glutamate resulting from MeHg exposure contributes to neuronal injury. N-methyl-D-aspartate (NMDA) receptor-binding memantine attenuates MeHg-induced neurotoxicity (6). It has also been shown that the HgCl2-induced reduction of cell viability is substantially attenuated by the application of a non-competitive antagonist of NMDA receptors (7). Although mercury-induced neuronal degeneration is suggested to invoke glutamate-mediated excitotoxicity, the underlying mechanisms remain poorly understood

Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Hopeoneday on February 20, 2022, 02:53:12 PM
Good response from chelation:
https://www.reddit.com/r/POIS_Science/comments/swyndk/pois_is_likely_heavy_metal_intoxication_and/

He had- I got symptoms right off the bat with .25 mg DMPS that went back and forth on round getting better to almost nothing now...
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: alerom on March 03, 2022, 02:48:22 PM
Hi everyone, this is my first post. I have been suffering from POIS for over a year and only connected it to POIS last 4 months.

First of all thank you for everyone that's participated, this forum was a life saver for me. I will write more another time about my story, but quicly i am 33 years old and was perfectly healthy before this happened to me.

I am interested in the mercury/heavy metal theory as this was my first inclin when i got sick. Then 6 months after that I only started getting some relief after taking zeolite which helped with some symptoms. I have for last 2 months implemented a gluten/lectine free diet and have also seen more improvement. Buf i am still not at 100%, i still suffer from fatigue and a pounding heart mainly within 2 days of 0 and the fatigue always lingers with me even outside POIS. But brain-fog has practically dissapeared with the new diet along with fasting.

So I want to try the ACC method, do you guys have a specific brand for ALA? And have you not tried DMSA before or just jumped straight into ALA. I've been on zeolite for 6 months so i reckon that has the same effect as DMSA. I have no amalgam fillings so i'm thinking of just going straight into taking ALA. I obviously don't think the only way to get heavy metal poisoning is through amalgam fillings.

Also apparently there is a liquid zeolite form that penetrates BBB . Thought that could be interesting.

We will get there:)  keeo fighting everyone
Title: Re: The root couse of POIS Mercury intolerance))leaky gut))Mercury retention))POIS
Post by: Hopeoneday on March 07, 2022, 11:55:29 AM
Intresting, all witnesses in this book mention some kind of alergies,
autoimunity etc...
https://books.google.co.id/books?id=dsR3Izgb4GUC&pg=PA405&lpg=PA405&dq=functional+dyspepsia+amalgams&source=bl&ots=up69NMmH-u&sig=ACfU3U0WwTwYnTcykr5MumlGNZYB4zyclg&hl=hr&sa=X&ved=2ahUKEwi1t_66vbL2AhUc4nMBHfN-DN4Q6AF6BAgsEAM#v=onepage&q=functional%20dyspepsia%20amalgams&f=false