Recent Posts

1

General Alternative Causes and Treatments of POIS / Re: Possible Cure for Pois. Pois Free for a Month

« Last post by Quantum on March 22, 2025, 07:47:15 PM »

Interesting, Ben.

From what you shared, I suppose you did not have a very healthy diet before that, so that your levels of vitamins were probably rather low.

A healthier diet has often been mentioned as a mean to lower POIS symptoms.  In your case, it's been quite a dramatic change.

Keep us updated !  I sure wish you to stay POIS-free

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Lifestyle Diary and POIS Summaries / Re: Warrior's Health Journal & POIS Protocol

« Last post by Warrior on March 22, 2025, 03:19:10 PM »

Since normalising D3, methyl donor supplementation has not been as necessary. Low D3 worsens POIS, mood, food sensitivities. Can also probably give the illusion of needing more B complex/methyl donors when really I just needed more balanced D3.

D3 and methyl donors work in tandem for normalising majority of my cluster symptoms it seems.

Side effects from b complex/methyl donors are likely just excess. Nicotinamide helps to remove/normalise excess. Can probs drop frequency of B complex to once per week with normal D3 lvls. Moving forward, I will make sure I have adequate D3 by sitting in the direct sun, before taking B complex.

D3 is priority #1.
B complex/methyl donors is priority #2 after initial replenishment.

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General Alternative Causes and Treatments of POIS / Possible Cure for Pois. Pois Free for a Month

« Last post by ben on March 21, 2025, 07:19:26 PM »

hi, everyone. a fellow pois sufferer is here.

first, i must say as far as i know i have struggled with pois. probably, it has been more than ten years.

initial years, the symptoms were mild. the years went by, things changed slowly that the symptoms became unbearable. then, i found myself here.

i read a ton of posts on this forum. hoping to find a cure, i have come across to some possible causes and treatments. most of them were related with my health problems. i was planning on implementing some of the treatments BUT...

at that time, i ran into an article about migraine. -i have migraine btw-. i skimmed through the article. basically, it says that carotenoids help with migraine.

so, here's our first possible helpful element: CARROT! it has carotenoids.

also, i have chronic fatigue and pains. for that matter i've read that it might be related to inflammation.

so, here's our second possible helpful element: ORANGE! a natural anti-inflammatory, rich in vitamin c.

i decided to:
- eat a carrot a day
- drink orange juice daily (one orange)

these two dietary addings were not, in fact, meant for pois but here's the story.

one day, i had a wet dream. i woke up feeling extremely tired with lower back pain. the anxiety was out of the roof.

that was the day i began eating a carrot and drinking orange juice.

the next few days were the same. intense pois symptoms. gradually, symptoms became milder. i was happy to made it to the 7th day because at the 8th day symptoms eases off. but...

at the 8th day morning i had another wet dream. i woke up instantly, feeling disappointed, rushed to the bathroom, taken a shower, couldn't sleep back, and waited for symptoms to come. i desperately waited, but nothing happened.

i was confused. i speculated that maybe the symptoms will come the next day. yet, the next day i had another pois free 24 hours.

few days later, another wet dream and another pois free days afterwards.

since then, to make sure i tested my pois. i ejaculated by masturbation 3 times up until now.

in total, it has been a month. no pois, for now. i'll keep on updating.

Mind you, i kept eating the carrot and drinking the orange juice daily for a month.

lastly, if anyone is wondering i didn't have migraine either. one stone two birds!

4

POIS Research / Re: 2025 POIS SCIENTIFIC RESEARCH STUDY

« Last post by demografx on March 20, 2025, 02:20:04 PM »

We now - - finally - - have the green light for the 2025 POIS Scientific Study to begin piloting!
https://tinyurl.com/5pjvsubj

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General Alternative Causes and Treatments of POIS / Re: chatgpt said my POIS might be dopamine depletion(POIS last for months)

« Last post by JayDeeSee on March 19, 2025, 01:47:55 PM »

Did it mention anything about what to do to counteract dopamine crash?

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POIS Research / Re: 2025 POIS SCIENTIFIC RESEARCH STUDY

« Last post by demografx on March 18, 2025, 05:39:46 PM »

Any news here?
The last post seems to be 17/3, which is today, but nothing seemingly new?

Hi Aladin,

The lab should be shortly ready to start recruiting/running healthy control participants - they are just waiting on a new temperature gauge, and the computer they are shipping from UNL’s lab to UCLA, to arrive on site there. The UCLA lab will be getting those shortly.

These delays have been getting UNL to be able to use the POIS funds to place orders with the new vendor and to send them to a new address at UCLA. These are frustrating bureaucracies, but they exist to make sure your money is spent only as allowed.

UCLA unexpectedly asked UNL to pay the travel to POIS participants using their cash cards, which was not what UNL had approved. UNL needs to approve this and they need to request the cards. However, they can start the study without this, as they already have approval for all the control participants as it is (they are not paid travel).

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General Alternative Causes and Treatments of POIS / chatgpt said my POIS might be dopamine depletion(POIS last for months)

« Last post by DEANNX on March 18, 2025, 12:03:42 PM »

i have POIS since the first time i masturbate, at first symptoms are mild, maybe slightly harder to focus and cognitive issues, the only symptom that i could noticed were that my face will look saggy and less firm after masturbate and need weeks to months to recover. but when i was around 20, i had a panic attack that last for hours, ever since that anxiety and depression become part of my pois and can last up to 3 months. if i have sex instead of masturbate symptoms are a lot weaker.
 
today i asked chatgpd about my pois and how my panic attack make it worse, it suggest that the reason for pois to last for months is due to dopamine depletion and panic attack happened 10 years ago future mess up my dopamine system hence the increase symptoms.

here is some of what it said:
Why Masturbation Might Worsen Your Depression for Months

There are several possible explanations:

1. Dopamine Depletion & Reward System Dysfunction
   ?   Masturbation causes a rapid spike in dopamine, followed by a crash.
   ?   In people with dopamine dysregulation, the post-orgasm crash can last days to months.
   ?   If your panic attack already caused dopamine exhaustion, this could make things worse.

✅ Signs This Is the Issue:
   ?   Feeling numb, unmotivated, or disconnected after masturbation
   ?   Pleasure from normal activities feels ?muted?
   ?   Low drive, energy, or focus

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POIS Research / Re: 2025 POIS SCIENTIFIC RESEARCH STUDY

« Last post by Aladin on March 18, 2025, 05:50:39 AM »

Any news here?
The last post seems to be 17/3, which is today, but nothing seemingly new?

9

Lifestyle Diary and POIS Summaries / Re: Warrior's Health Journal & POIS Protocol

« Last post by Warrior on March 17, 2025, 06:37:12 PM »

Food sensitivity symptoms accumulate when repeatedly tested. If I eat a non AB meal w/ starches after 7 days of eating strict AB, the inflammation is minimal if at all visible/felt. If I continually eat non AB foods daily for 3 days straight for example, by the 3rd day I really start to feel the negative symptoms and depletion at intense levels.

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POIS Research / Re: Genetic profile results

« Last post by Quantum on March 16, 2025, 08:43:15 PM »

Yes, I pay attention to my protein intake.  And, whenever I do sport, I use my ammonia detox supplements:  L-carnitine, L-ornithine, magnesium malate, and L-citrulline.

Hi Quantum!

Do you still take L-ornithine regularly? What is the dose you use? I tried to incorporate it into my daily regime, but for some reason I get a really troublesome side-effect. I got 700 mg capsules and even if I pour the powder in water this would still appear. About 6 hours after intake some kind of temporary and moderately strong constrictive feeling would occur around the heart, which is kind of scary. Have you not felt anything such? Barely perceptibly, but I can still feel it when I only take half the capsule (350 mg).

Hi, Progecitor,
Yes, I still use Ornithine, L-Carnitine and magnesium malate before sport.   Not daily, but two times a week,  before I play badminton (winter) or tennis ( summer) for about 1 hour and a half.  Any sport activity longer than 30 minutes will cause me symptoms that fit some degree of hyperammonemia. 

Before sport, I take 500mg L-ornithine and 500mg L-carnitine, and magnesium malate ( giving 140mg of magnesium and 800 mg malic acid).  I no longer take L-citrulline..  I also take a capsule of Ceylan cinnamon , which help prevent ammonia production (Cinnamaldehyde inhibits phenylalanine ammonia-lyase (PAL), an enzyme involved in ammonia production)
I also take another 500mg of L-carnitine after sport.
I teke other supplements before and after sport as well, but those are the ones specific for preventing higher level of ammonia in my body,.

I have no side effect with L-ornithine or the other supplements I mentioned.

since I implemented this anti-ammonia protocol, I recover way better from sport.