Author Topic: Milnacipran - completely stopping my brain fog (Read 98450 times)

Muon · « **Reply #220 on:** March 24, 2021, 03:17:35 PM »

Quote from: Laotzu1980 on March 24, 2021, 11:47:50 AM

Why are other members not trying this?

Milnacipran isn't the only one. Here is another example: https://en.wikipedia.org/wiki/Picamilon
https://poiscenter.com/forums/index.php?topic=792.0
People tend to try stuff that is readily available (OTC) before they move on to psychiatric drugs like milnacipran.

Laotzu1980 · « **Reply #221 on:** March 24, 2021, 09:03:58 PM »

Picamilon is not available in many countries as far as I can see. I will try to find it online somewhere to test it. Thanks for mentioning.

Milnacipran is available in many, quite cheap, and only required before O (not every day) which seems ideal. If people are suffering that badly and unable to function, it amazes me that they do not try these drugs, or at least report back after trying.

If anyone else has tried it, or any other drugs that help prevent severe brain fog, anxiety, etc, after O, it would be great to know.

Muon · « **Reply #222 on:** March 25, 2021, 06:55:55 AM »

You can find a compilation here: https://poiscenter.com/forums/index.php?topic=3551.0

Laotzu1980 · « **Reply #223 on:** March 25, 2021, 10:03:10 AM »

Amazing. Thanks Muon!

berlin1984 · « **Reply #224 on:** March 25, 2021, 02:28:42 PM »

Quote from: Laotzu1980 on March 24, 2021, 11:47:50 AM

Why are other members not trying this? Only one other member tested it after him and also had some success.

As others mentioned, it's the OTC problem.

Plus there is a lot of cures to be found in this forum and people are dissapointed with trying them and failing to suceed.

OpiesDad · « **Reply #225 on:** April 05, 2021, 01:34:56 AM »

I have stumbled on the norepinephrine theory of POIS too and have also been cured (so far) by another SNRI....Wellbutrin. Wellbutrin also blocks reuptake of dopamine so it can replace adderrall for those with ADHD. The last 3 weeks since I started have been like a miracle for me. I have O'd 5 or 6 times, I have light physical symptoms, achiness, heavy muscles and a bit of fatigue, but the emotional and cognitive effects are ZERO.

I continue to take propranolol, and an occasional antihistamine. Also, I take sudafed to further increase the norepinephrine.

I'd STRONGLY recommend those who haven't explored this avenue to do so under a doctor or psychiatrist's supervision.

This is the way.

Laotzu1980 · « **Reply #226 on:** April 05, 2021, 03:15:56 AM »

Interesting! Do you only take it before O or do you take it every day? So glad you have success with it so far!

berlin1984 · « **Reply #227 on:** April 06, 2021, 03:52:28 AM »

Wellbutrin discussion continues in https://poiscenter.com/forums/index.php?topic=3755

Laotzu1980 · « **Reply #228 on:** April 16, 2021, 04:49:37 AM »

Is Hurray still having success with Milnacipran? I assume he is, since he hasn't reported back. No news is probably good news.

hurray · « **Reply #229 on:** April 26, 2021, 06:27:23 PM »

Quote from: Laotzu1980 on April 16, 2021, 04:49:37 AM

Is Hurray still having success with Milnacipran? I assume he is, since he hasn't reported back. No news is probably good news.

Yes, it still works. I'm a lucky guy.

hurray · « **Reply #230 on:** April 26, 2021, 06:34:19 PM »

Quote from: OpiesDad on April 05, 2021, 01:34:56 AM

I have stumbled on the norepinephrine theory of POIS too and have also been cured (so far) by another SNRI....Wellbutrin. Wellbutrin also blocks reuptake of dopamine so it can replace adderrall for those with ADHD. The last 3 weeks since I started have been like a miracle for me. I have O'd 5 or 6 times, I have light physical symptoms, achiness, heavy muscles and a bit of fatigue, but the emotional and cognitive effects are ZERO.

I continue to take propranolol, and an occasional antihistamine. Also, I take sudafed to further increase the norepinephrine.

I'd STRONGLY recommend those who haven't explored this avenue to do so under a doctor or psychiatrist's supervision.

This is the way.

That's good news OpiesDad

Wellbutrin (bupropion) sadly hasn't worked for me in the past - in my case, I think the dopamine reuptake inhibition makes me feel anxious and jittery. But it's great that it works for you, and could potentially work for other people.

Laotzu1980 · « **Reply #231 on:** May 10, 2021, 07:21:08 AM »

Funny Hurray, you mentioned Amitriptyline as what you were going to ask the doctor for. That is what the neurologist gave me. It didn't knock out brain fog and anxiety, but it did appear to stabilise mood which within POIS swings like a dead cat. I also didn't feel the body was 'depressed'. But without the brain fog and concentration, it is all useless, as you know... 🙂

hurray · « **Reply #232 on:** May 10, 2021, 12:51:45 PM »

Quote from: Laotzu1980 on May 10, 2021, 07:21:08 AM

Funny Hurray, you mentioned Amitriptyline as what you were going to ask the doctor for. That is what the neurologist gave me. It didn't knock out brain fog and anxiety, but it did appear to stabilise mood which within POIS swings like a dead cat. I also didn't feel the body was 'depressed'. But without the brain fog and concentration, it is all useless, as you know... ?

Yes, that was going to be the next one on my list. I was looking specifically at drugs that had a norepinephrine reuptake inhibition component, and amitriptyline is widely available. I've tried a number of other drugs with an NRI component without success, but I'm definitely interested in other people's experiences with them.

lw · « **Reply #233 on:** May 11, 2021, 05:57:23 AM »

Congratulations dear friends!
As I've been insisting on, POIS must be handled by professional psychiatrist. You've seen the results.
Good luck everybody!
btw I'm still making progress by cold showers and rexepi combi

demografx · « **Reply #234 on:** May 11, 2021, 06:18:40 AM »

Quote from: lw on May 11, 2021, 05:57:23 AM

As I've been insisting on, POIS must be handled by professional psychiatrist.

I have been with this forum and it’s predecessor for over 14 years, and I think I can speak for some other POISers here as well: from my personal experience with psychiatrists over a period of many, many years, they have helped me understand my neuroses, but they have done very-little-to-nothing for my POIS.

Best wishes, lw!

Laotzu1980 · « **Reply #235 on:** May 11, 2021, 06:22:20 AM »

I look forward to trying Milnacipran when it is possible to get some..... Glad all well with you still.

Iwillbeatthis · « **Reply #236 on:** May 11, 2021, 08:06:56 AM »

Quote from: lw on May 11, 2021, 05:57:23 AM

As I've been insisting on, POIS must be handled by professional psychiatrist. You've seen the results.

No...

Laotzu1980 · « **Reply #237 on:** May 11, 2021, 10:40:48 AM »

Hurray, Quantum, and anyone else...

If you have any ideas for drugs to try, I see the neurologist on Friday, and then again on the following Tuesday, and every 4 days until something gives me some relief from this hell...

I will try ANYTHING with the doctors approval (just once, as a pre-pack) that anyone recommends providing it seems suitable or has worked for others. This doctor is happy to let me try whatever this group thinks may help. Here in Thailand hospitals they dispense the exact amount of pills the doctor asks for, rather than needing to buy a whole box so it is cheap as he will prescribe me with only 2-3 pills of each.

The Amitriptyline was a no-go.
I did not try the Methylphenidate as a pre-pack yet, but I did try it within POIS and it didn't help concentration/brain fog at all. He gave me the 18mg Sandoz slow release (over 8 or 9 hours) which cannot be taken after 2 pm, so I may ask for the immediate release to try it as a pre-pack.

Anyway, if anyone has any ideas, let me know. 🙂

Iwillbeatthis · « **Reply #238 on:** May 11, 2021, 01:34:04 PM »

Amitriptyline is a really dirty drug as it works on so many receptors hence why it causes so many people side effects and bad withdrawal symptoms, there's even a facebook group called amitriptyline withdrawal because of this. People seem to have a nightmare coming off of it compared to other antidepressants, I'm surprised your doc prescribed it to you for non daily use. Shows these "professionals" know nothing...

Laotzu1980 · « **Reply #239 on:** May 12, 2021, 02:01:31 AM »

How about:
- Levomilnacipran (if I can get it here, which is different to milnacipran)
- Venlafaxine

Have any members had success with either of these (I don't see much in the search history for these, from anyone that has had success).

News:

Author Topic: Milnacipran - completely stopping my brain fog (Read 98450 times)