Author Topic: Alcohol and POIS  (Read 24618 times)

Quantum

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Re: Alcohol and POIS
« Reply #40 on: March 07, 2016, 12:20:24 AM »

Quote from: Quantum
In my current method, I use 3 NMDAR blockers  ( magnesium, flax seed oil and L-theanine/green tea) that help reduce the excitotoxicity in the brain by blocking the NMDA receptors, so whatever the agonist is, the receptor is blocked.  I also use IDO and TDO inhibitors, that prevent the production of the toxic metabolites I suppose are at play in the brain while in POIS.  The reasons I state are only a hypothesis, but however,  my pre-pack of supplements works for me, whatever the exact scientific reasons may be.


Hi Quantum,
I read about your pre-pack, I don't know if I interpret this article right.
http://www.ncbi.nlm.nih.gov/pubmed/17230642#
But could perhaps creatine among the other things mentioned in this article be interesting for use in the pre-pack ?


Hi erik !

Good point, creatine has indeed NMDAR blocker properties.  I have tried it a few times, a few months ago, but even at low dose, it makes may urinate at a very high frequency for several hours  ( up to 24 hours for a single dose), so it was not worth it for me, because of this particular side effect it has for me.  The mechanism of this increased urination may be osmotic diuresis, I suppose, since creatine is a very small molecule, and can cause this in the kidney tubules.  This effect is not often mentioned, but I did have found other cases of this mentioned on the internet, often on forums by body builders that have tried using it. 

Since I have already other NMDAR blockers that work well without side effects, I have let go of creatine.  It may be useful for other POIS sufferers, as it is usually well tolerated.  If anyone get good results with it, let me know.   
« Last Edit: March 07, 2016, 12:23:57 AM by Quantum »
You are 100% responsible for what you do with anything I post on this forum and of any consequence it could have for you.  Forum rule: ""Do not use POISCenter as a substitute for, or to give, medical advice" Read the remaining part at http://poiscenter.com/forums/index.php?topic=1.msg10259#msg10259

hurray

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Re: Alcohol and POIS
« Reply #41 on: February 18, 2017, 09:13:31 AM »
I was reluctant to post about this before, but a couple of beers before O does reduce all subsequent POIS symptoms for me. As mentioned elsewhere in the thread, this effect could well be caused by the reduction of stress/anxiety. And there are plenty of other, better, ways to achieve that than drinking alcohol.

VictorHugo

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Re: Alcohol and POIS
« Reply #42 on: June 14, 2017, 01:56:08 PM »
As a proponent of Auto Immune Protocol (AIP) Diet and having experienced the positive effects of this diet, I would say be very very cautious with alcohol. It is said that POIS is an Auto Immune Condition and is now well known (I like to think so) in the Auto Immune Circle that AIP reverses Auto Immune Disease. AlP diet requires you to not consume Alcohol since it damages our intestines, which is where the Auto Immune Conditions start from - A 'Leaky Gut'.

Keeping my mail short since its late here in India. Do checkout this article on PaleoMom website about Alcohol and AIP: https://www.thepaleomom.com/the-whys-behind-the-autoimmune-protocol-alcohol/

This site is also a good starting point to learn more about Auto Immune Diseases and AIP diet.

Thanks for your post and stay healthy.

wolf

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Re: Alcohol and POIS
« Reply #43 on: June 15, 2017, 01:25:25 AM »
Hi, it is also the case for me when drinking alocohol after an O my symptoms are reduced greatly, It helps the most with concentration and my brain fog as well as my social anxiety and it also lessens my physical symptoms too but not fully. I also have been taking viagra 25 or 50 mg after an O at times along with l -Citrulline capsules and this at times seems to have  alleviated some of my symptoms and in addition increased my sex drive tremendously lol. I am also planning on adding vitamin B as well and see if that can help too. and for anybody wanting to try the viagra after an O just make sure you are ok to take it because I hear it can be dangerous to some.
Also I have noticed that taurine does help me aswell


ThisType

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Re: Alcohol and POIS
« Reply #44 on: June 17, 2017, 11:19:27 AM »
Beer contains a moderate level of betaine. It might be worth checking the discussions on beets (high betaine), eggs (high choline which is a precursor to betaine) and related (I see a few on choline, etc) to see if there are commonalities.
https://www.ars.usda.gov/ARSUserFiles/80400525/Articles/IFT2004_Betaine.pdf

TT

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Re: Alcohol and POIS
« Reply #45 on: July 03, 2017, 03:01:28 AM »
Alcohol is a CNS depressant, if you suffer of depression triggered by POIS I don't think alcohol is a good idea.

Investigator

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Re: Alcohol and POIS
« Reply #46 on: January 05, 2018, 12:35:31 AM »
For me, sometimes alcohol improves the POIS symptoms. It seems to work (sometimes). Not always, just sometimes.

Vincent M

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Re: Alcohol and POIS
« Reply #47 on: February 12, 2018, 08:34:41 AM »
Alcohol decreases my POIS symptoms both temporarily and long term. Temporarily it decreases physical pains and anxiety. It helps me long term by improving blood circulation and aiding digestion.  It also improves my cognition and memory the next day in a way that feels similar to the way increasing acetylcholine via huperzine affects me.

1-3 beers is what I usually stick to in one day. I suspect wine is the most healthy form of alcohol, but it's too expensive for me and I prefer the taste of beer.
Taking ginger tea, no wheat, fenugreek+green tea/garlic, saw palmetto, niacin, boswellia, huperzine, B complex and nutmeg. See my treatment summary post for more info: http://poiscenter.com/forums/index.php?topic=81.msg3513#msg3513

hurray

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Re: Alcohol and POIS
« Reply #48 on: February 12, 2018, 01:09:44 PM »

Some studies show that ethanol inhibits the release of oxytocin:

http://www.eje-online.org/content/44/4/593
https://www.ncbi.nlm.nih.gov/pubmed/1574949

Could it be that oxytocin (or lack of it) has a strong link to our POIS symptoms?

demografx

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Re: Alcohol and POIS
« Reply #49 on: February 12, 2018, 01:27:45 PM »
hurray, I posted this a while back, you might have seen more at the nakedscientists.com POIS forum.


...Orgasm culminates in a release of oxytocin (the 'cuddle hormone'). In Europe, they even sell a nasal spray with oxytocin.

But it can be a dangerous drug to take.

We had a lot of discussion @ TNS/POIS about oxytocin (possible POIS treatment?). You can copy and paste this in your Google search box and a number of oxytocin discussions will come up:

oxytocin POIS site:http://thenakedscientists.com

Use spaces and no-spaces as shown directly above this line.
« Last Edit: February 12, 2018, 02:23:35 PM by demografx »
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

hurray

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Re: Alcohol and POIS
« Reply #50 on: February 12, 2018, 02:15:15 PM »
Hi Demo, good to see you :)

Yes, you are correct, oxytocin itself should never be used outside a hospital. Oxytocin as used in medicine is useless for POIS anyway because it doesn't cross the blood-brain barrier. We spent a while discussing oxytocin on the Naked Scientists thread, there are some excellent posts on there.

I find it a curious coincidence that 2 of the main things that affect my POIS symptoms (alcohol and fenugreek) both have a strong link to oxytocin (the kind we make ourselves inside the hypothalamus). Is it a false lead, or could there be something to it?




demografx

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Re: Alcohol and POIS
« Reply #51 on: February 12, 2018, 02:29:04 PM »
hurray, great to see you...many years forum-ing together! :)

Like you, I think there’s something to it. That’s why I posted the Naked Science forum link above: check out these old oxytocin/POIS posts.

Perhaps one of our more scientific-minded Members at POISCenter here can chime in? :)

Gentlemen (or lady visitors): any new thoughts about oxytocin and POIS?


« Last Edit: February 13, 2018, 01:07:13 PM by demografx »
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

berlin1984

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Re: Alcohol and POIS
« Reply #52 on: July 29, 2020, 02:33:16 PM »
Cross linking some things:

2. Alcohol: I occasionally drink alcohol and it removes my symptoms to 90% temporarily. Although I dont advice this for others due to the obvious other effects of alcohol

FYI, unfortunately, alcohol fix POIS for me, if I get drunk, the next day i'm 100% POIS free. Dunno why, maybe alcohol reduces brain inflammation or something like that.

But - the possibility of me getting POIS seems to be greatly reduced if I drink alcohol before O. I have no idea why this should be. Fenugreek, a few beers and some fatty/protein containing food before O is one of the most reliable ways that I have found of avoiding POIS. Stiill, I can't recommend it - drinking is just substituting one problem for another.

-Alcohol (ethanol): The only thing that has been able to prevent and fix POIS entirely. If I'm drunk, I can ejaculate as much as I want and next day, I'll have just a hangover but no POIS at all. If I'm under POIS and get drunk, next day i'll be POIS free.

berlin1984

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Re: Alcohol and POIS
« Reply #53 on: July 29, 2020, 02:34:20 PM »
https://www.reddit.com/r/hangovereffect/
A community that feel relief from hangovers and are looking for answers as to why
Most of us are diagnosed with ADHD and exhibit depression, anxiety and fatigue but feel complete remission from all symptoms when hungover from alcohol. If you feel the same way, join us and let's find a cure.

b_jim

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Re: Alcohol and POIS
« Reply #54 on: January 19, 2021, 08:22:58 AM »
Amazing experience for me today.
I drank a glass of wine just some minutes after ejaculation.
Wow, amazing. It at least triples the effects of alcohol. During 5 minutes I need to stay seated with strong brain fog and "cutted legs" feeling.

First time I did this. I usually drink very few alcohol.
A clear proof of up and down levels of neurotransmitters after ejaculation for me.


Taurine = Anti-Pois
Suffering from lyme disease

Iwillbeatthis

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Re: Alcohol and POIS
« Reply #55 on: January 19, 2021, 09:03:03 AM »
Why was it an amazing experience if it gave you strong brain fog haha. I can't tolerate alcohol at all now I feel horrible on it.

drop247

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Re: Alcohol and POIS
« Reply #56 on: January 19, 2021, 09:45:49 AM »
It could be the histamine. Wine is loaded with it.

demografx

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Re: Alcohol and POIS
« Reply #57 on: January 19, 2021, 02:44:42 PM »
Amazing experience for me today.
I drank a glass of wine just some minutes after ejaculation.
Wow, amazing. It at least triples the effects of alcohol. During 5 minutes I need to stay seated with strong brain fog and "cutted legs" feeling.

First time I did this. I usually drink very few alcohol.
A clear proof of up and down levels of neurotransmitters after ejaculation for me.

10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

Nas

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Re: Alcohol and POIS
« Reply #58 on: January 20, 2021, 06:58:09 PM »
Why was it an amazing experience if it gave you strong brain fog haha. I can't tolerate alcohol at all now I feel horrible on it.

That's a strong clue.
But what would you describe the experience? It made it worst or better?

BoneBroth

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Re: Alcohol and POIS
« Reply #59 on: February 28, 2021, 04:12:29 AM »
I had a glass of ecological white wine yesterday, 12% alcohol, and it was affecting me for an hour, and 5 hours later my pulse increased and i had a horrible night with nighmares and headache, it was worst at about 1-2 am when the liver is doing its detoxification program. Or was it the histamine???