Author Topic: Is POIS a version of CFS?  (Read 11404 times)

Mr Raba

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Re: Is POIS a version of CFS?
« Reply #90 on: May 12, 2021, 10:57:51 PM »
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: The Human Herpesviruses Are Back!

Furthermore, it was demonstrated that EBV dUTPase is secreted in exosomes from chemically induced Raji cells at sufficient levels to induce NF-?B activation and cytokine secretion in hDCs and PBMCs through a TLR 2-dependent mechanism [72]. Exosomes are produced by numerous cell types, have been implicated in numerous diseases, including ME/CFS [84], and are capable of trafficking to various organs within the body, including the brain, where they function as intercellular messengers.

Virus changing exosome content?

Exosomes in human semen carry a distinctive repertoire of small non-coding RNAs with potential regulatory functions

Extracellular vesicles in human semen modulate antigen-presenting cell function and decrease downstream antiviral T cell responses

A downregulated DBH can be problematic when you need a burst of norepi during orgasm via DBH.
Simultaneous onset of CFS and POIS since Feb 1993. Married since 1989.

Helped by Immunocal (I explained how to take in previous posts).  Some relief on day one and day two.  It affects neurotransmitters.