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What is POIS / Re: Is POIS a version of CFS?
« Last post by demografx on February 28, 2025, 12:26:00 AM »

Maybe it's an option you [Progecitor] put a tl;dr in front of your posts that contain an AI summary?

Brilliant, Berlin!!
1.Berlin, I used tl;dr in front of this AI below twice
The question “what is life?” is complex and has been debated by philosophers, scientists, and thinkers across various disciplines. Here’s a concise overview:
Biological Perspective:
   •   Life is generally defined by characteristics such as growth, reproduction, functional activity, and continual change preceding death.
   •   It involves complex interactions at the molecular, cellular, and organismal levels.
Philosophical Perspective:
   •   Life can be seen as a journey of experiences, emotions, and consciousness.
   •   It often involves questions about purpose, meaning, and existence.
Cultural and Social Perspective:
   •   Life is shaped by relationships, culture, and societal norms.
   •   It encompasses personal growth, learning, and contributions to the world around us.
In summary, life is a multifaceted concept that can be understood through biological, philosophical, and cultural lenses.


2.…and I got this!
Life is a mix of biology, consciousness, and experiences.

3. using tl;dr only once
Life is a complex mix of biological processes, personal experiences, and social interactions that shape our existence and understanding of the world.

Amazing, Berlin! :)
72
POIS Research / Re: POIS 2025 NORD SCIENTIFIC RESEARCH STUDY
« Last post by demografx on February 27, 2025, 06:41:46 PM »
“What Happens to Your Brain When You Have Sex” | Reader's Digest

These chemical changes help regulate and pace sexual activities, according to
Dr. Nicole Prause,
POIS 2025 Scientific
Research Study
Co-Investigator
.

One of these neurotransmitters is dopamine, which ...

https://www.rd.com/health/wellness/happens-to-brain-when-have-sex/
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was your doctor a kinesiologist? What drugs did you use?

ANYWAY I went to the kinesiologist on Monday and he prescribed me an antiparasitic drug but in addition to this his specialty is to give a natural antiparasitic: that is, computerized water that gives with a different frequency from person to person, and is personalized with a different frequency for each person and is made with a machine that comes from Australia: I will let you know in the future how it goes, but he is one of the few in the world who says he knows everything about intestinal parasites, he seems really expert. He also indicated some supplements for me to take, the right ones for me through neuromuscular tests. And I will have to eliminate for 28 days the foods that bother me, namely: yeast, gluten, lactose, sugar and casein.
74
Lifestyle Diary and POIS Summaries / Re: Warrior's Health Journal & POIS Protocol
« Last post by picasso1122 on February 27, 2025, 12:00:02 PM »
Frequent methyl donor supplementation is still necessary long-term, regardless of how much I release or what diet I’m on. It’s the only supplement I need to consistently take.

When I stop taking my B complex for a week, I begin to get symptoms that I associate with a depletion of methyl donors.

I start getting more anxious than usual, weird facial sensations, brain fog, dusky etc. These all improve significantly when I take methyl donors again.

However the B complex I’ve been relying on for the past few years equally continues to give me side effects. So currently trying to identify the most important nutrients within the B complex. I’ve stated this numerous times but never actually gotten around to doing it lol.

Starting off with methyl B12, folic acid, and B6. Haven’t taken B complex for ~ week or so, and began feeling symptoms today. Took b12, folic acid, and b6 and immediately felt better. Will see how I feel in the coming days as well.

hi , man.my sincerely greetings. i hope  you to be good.
i feel in debt about  your video and i  want to say  though my symptoms are not quite the same as your but they are some similarities.
i just wondered how you ever tried anticholinergic drug like Baclofen. these thing make me feel better. i tried them for considerable amount of time and that makes me feel better. if you haven't tried one maybe it is not a bad idea to play this kind of drug on trial
75
Lifestyle Diary and POIS Summaries / Re: Warrior's Health Journal & POIS Protocol
« Last post by Warrior on February 27, 2025, 04:04:14 AM »
Frequent methyl donor supplementation is still necessary long-term, regardless of how much I release or what diet I’m on. It’s the only supplement I need to consistently take.

When I stop taking my B complex for a week, I begin to get symptoms that I associate with a depletion of methyl donors.

I start getting more anxious than usual, weird facial sensations, brain fog, dusky etc. These all improve significantly when I take methyl donors again.

However the B complex I’ve been relying on for the past few years equally continues to give me side effects. So currently trying to identify the most important nutrients within the B complex. I’ve stated this numerous times but never actually gotten around to doing it lol.

Starting off with methyl B12, folic acid, and B6. Haven’t taken B complex for ~ week or so, and began feeling symptoms today. Took b12, folic acid, and b6 and immediately felt better. Will see how I feel in the coming days as well.
76
Wow, this is really interesting! I had started taking choline. So, it’s really interesting to read this.
What are you taking now? Any new discoveries?

Thanks for your amazing contributions!
77
POIS Research / Re: 2025 POIS SCIENTIFIC RESEARCH STUDY
« Last post by demografx on February 25, 2025, 07:03:43 PM »
Dr. Nicole Prause, co-Investigator of our upcoming
***2025*** POIS Scientific Research Study got a chance to talk a little POIS in this podcast!
https://tinyurl.com/2smn7jk7

Please watch the above video to get a better idea of what’s coming soon with our upcoming
POIS 2025 Scientific Research Study!

Demo


interviews Dr. Nicole Prause!

Dr. Nicole Prause
**2025** POIS Science Investigator

https://tinyurl.com/475vned4
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“Excellent response to DHEA treatment in a male with [POIS] post orgasmic illness syndrome” (2025)

https://www.endocrine-abstracts.org/ea/0109/abstracts/poster-presentations/adrenal-and-cardiovascular/ea0109p54/

DHEA Modulates Immune Function: A Review of Evidence
https://sci-hub.se/https://www.sciencedirect.com/science/article/abs/pii/S0083672918300347


…Excellent response to DHEA treatment[/POIS]
Thanks, passing-along your post>2025 POIS/Science Group!

“Fascinating!”, per 2025/POIS Science Group

Thanks again, Muon! :)
79
What is POIS / Re: Is POIS a version of CFS?
« Last post by demografx on February 25, 2025, 04:31:09 PM »
FYI I took this post:

If I could tell you in one sentence I would have done so, but you have to see the whole process to understand how it all comes together. I am not exactly sure how much hypoxia is involved, but ROS is a certain culprit and there is clearly a glycolytic shift in our metabolism partly due to mitochondrial dysfunction. Mitochondrial dysfunction itself may come about due to a variety of reasons (e.g. sepsis, senescence, autoimmunity, etc). If we consider the treatments that we, ME/CFS and long covid patients have used with some degree of success, then it is easy to see that HIF-1a regulation is majorly involved in disease control. It is especially interesting to see that post-exertional malaise (PEM) in long covid patients last for about a week, similarly to a POIS episode, when there is a back shift towards oxidative phosphorylation. However the tricarboxylic acid (TCA) cycle remains impaired with somewhat elevated glycolytic metabolites even at baseline. This is quite relevant from my point of view as I have POIS/CFS and this exactly could explain the difference between my acute (dominated by POIS) and chronic phases (dominated by CFS).
and pasted it into ChatGPT and asked it to dumb it down into easier language and summarize it to 3 sentences (twice):
Quote from: ChatGPT

The condition involves problems with how the body produces energy, often due to issues with the mitochondria. Some treatments for ME/CFS and long COVID focus on a protein called HIF-1a, which seems important for managing symptoms. The way energy shifts in the body during these conditions may explain the similarities between long COVID and POIS.
Maybe it's an option you put a tl;dr in front of your posts that contain an AI summary?

Brilliant, Berlin!!
80
For the record: I am still taking TTFD and like it.
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