My experiment:
1. Niacin 200-600mg before O, do not help, but one POISer in China benefit from it.
2. Ketotifen and Pemirolast potassium and loratadine, they are all mast cell stablizers. At first, it help 30%,but after two week, it did not help. One POISer said it was the same for him. But another POISer in China said loratadine can help him.
3.Fish oil, 2022.1.15-Now, 2022.1.19, I ejaculated, did not see any good result. Need to observe.
4.Betahistine, a kind of H3 receptor antagonist, take one capsule a day for five consecutive days,did not help.
5. Raw garlic every day, do not help.
6.Votalin, take two capsule a day for 14 consecutive days,did not help, one POISer said it did not help him too.
7. gluten-free diet.2022.1.16, after 2 weeks of gluten free-diet, I ate a bowl of noodles made of wheatmeal for my lunch, and I found that I become sleepy in the afternoon, it seem that gluten will make me get into slight-POIS state, so I think gluten is harm for me and I will keep gluten free diet.
8. 2022.1.28, I went to hospital to test SIBO and it is positive, my doctor prescribed Bifidobacterium Lactobacillus triple viable tablets, a kind of probiotics and Trimebutine maleate dispersible tablets for me, and I will take medicine for fourteen days. After 14 days, I will do the SIBO test again. It is very peculiar that I neither diarrhea nor constipation(defecate twice a day), so even my doctor is very surprised with my positive result, and she said my result is very far from normal.9. 2022.1.29, I decide to eat low FODMAP diet.
10. From 2022.2.5, I decide to intake vitamin D 1000IU everyday because I found I have abnormal white skin(even whiter than Caucasian as an Asian), maybe it shows that I am lack of sunshine.
11. In 2022.2.6, I bought Relora@Now and Fenugreek@GNC, I will take them at the same time and report the result.
12. Ingesting calcium gluconate for two months ,0.5g-2.0g everyday, sometimes makes me diarrhea, did not help.
13. In 2022.2.10, I do the SIBO test again, it is positive but not so serious (In the first test, the peak of hydrogen is 198ppM and methane is 14 ppM, this time they are 27 ppM and 13 ppM respectively), so my doctor prescribe Bifidobacterium lactis triple live tablets and Compound Lactobacillus acidophilus tablets for me for the next 30 days. He also suggests me that if it does not help me, I can do the Fecal transplant but I have not so much time now so I refuse to do it. I also ask me doctor why he does not prescribe antibiotic for me, he says antibiotic may result in secondary infections so he just prescribe probiotics. It is a pity that I did not test my free T and vitamin in my blood today because I saw the wrong doctor, I will see one of the best gonadal endocrine team tomorrow and then test vitamin etc.
13. From 2022.2.12, I will eat nutrients as follow: 5000IU vitamin D@doctor's best everyday. One capsule B50@Now every two days.Two capsule Fenugreek@GNC everyday. Fish oil, Zinc gluconate 70mg(that is Zinc 10mg) everyday. In 2022.2.11, my doctor test a lot of thing within my blood but the results wasn't released yet. I will post them as soon as possible.
My test:
1.Brain MRI---normal.
2.Cervical vascular Doppler ultrasound---normal.
3.sex hormone->FSH LH E2 P T PRL before and after O----normal (But I did not test my free T, I will test it in some days).
4.SIBO (first time)----positive, H2 198, CH4 14.
5.SIBO (second time)----positive, H2 27, CH4 13.6.Color Doppler ultrasound of testis, epididymis and spermatic vein---normal.
7.Dehydroepiandrosterone sulfate 394.60ug/dl----normal.
8.17? -OHP--0.58ng/ml---normal.
9.Sex hormone binding protein---23.44nmol/L---normal.
10.Vitamin B12---540pg/ml---normal.
11.25-hydroxy vitamin D----14ng/ml, far lower than normal(above 30ng/ml).
11.Free triiodothyronine---5.84pmol/L---normal.
12.Free thyroxine----19.27pmol/L----normal.
13.Thyrotropin---1.002mU/L---normal.
14.albumin---50.4g/L---normal.
15.electrocardiogram---normal.
16.potassium---4.08mmol/L---normal. sodium---140.2mmol/L---normal. chlorine----98.9mmol/L---normal. calcium----2.500mmol/L---normal.
17.Chest CT---normal.
18.Pituitary MRI plain scan (3.0T)---normal.
19.DHT----830.67pg/ml---normal.
20.AMH----22.27ng/ml, Slightly higher than normal range(2.04-19.22),but my doctor said it is not serious, so she refused to prescribe any medicine for it.(But I think maybe POIS is caused by it, anyway, I will try vitamin D and other thing first, because supplementing sex hormones are dangerous). And my doctor said my sex hormones are in the critical value of the normal range, so I guess maybe this is why I have POIS, a kind of sub-health illness.21.Alanine aminotransferase and Aspartate aminotransferase,122U/L and 75U/L respectively, Close to twice the normal value. My doctor prescribe Polyene Phosphatidylcholine Capsules for me. Recently I am trying Fenugreek@GNC(But I have no ejaculation), https://shmabstracts.org/abstract/the-dangers-of-herbal-supplements-a-case-of-acute-liver-injury-from-fenugreek/ this shows that maybe it is Fenugreek harms my liver, so I decide to stop taking Fenugreek, and just take vitamin D@Now, vitamin B-50@Now, Zinc gluconate made in China, fish oil made in China, vitamin K2@doctor's best, calcium and magnesium capsule@Now. What's more, the other two Chinese POISer test his liver every year and it is normal, different with me, so I think maybe it is not the cause of POIS
