Author Topic: Exercise intolerance - please help  (Read 5394 times)

mike_sweden

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Re: Exercise intolerance - please help
« Reply #20 on: January 01, 2021, 10:43:19 AM »
when you exercise, try to breath through mouth and not nose, it makes a lot of a difference for me

i must remember myself to breath through mouth and its annoying, but it helps a lot

it should of course not be like that but please give it a try

my nose is clogged and i think it strains my body significantly

takedrugstoletgo

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Re: Exercise intolerance - please help
« Reply #21 on: January 03, 2021, 07:31:21 AM »
I have no advice but i have the same problem with exercise intolerance. Usually intense exercise triggers POIS for me and i feel extremely tired for days after exercising with tachycardia & flu like symptoms. It sounds like PEM (post exertional malaise) which is also common in CFS, dysautonomia etc.

Aladin

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Re: Exercise intolerance - please help
« Reply #22 on: January 03, 2021, 08:20:43 AM »
I have the same experience, but mainly when I start sporting after a while not having done much or after overdoing it. I think it must have to do with an inflammatory response that triggers POIS...
Generally, sport helps me to feel good.



Muon

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Re: Exercise intolerance - please help
« Reply #25 on: January 17, 2021, 05:27:20 PM »
Reduced tolerance of exercise in fibromyalgia may be a consequence of impaired microcirculation initiated by deficient action of nitric oxide

"The cycle is firstly initiated decrease of production of nitric oxide in the endothelial level by some trigger factors."

Exercise and the Nitric Oxide Vasodilator System

The tachycardia seems to indicate higher sympathetic activity. There could be something wrong with adrenergic or nitrergic tone. VEGF/histamine or other inflammatory substances could lead to vasodilation, the body could counter this by increasing sympathetic tone. The first paper talks about the reverse, as in reduction of the latter.

Quantum talks about a "sympathetic system high"...idk, I had those as well  in the past and it's different. It lacks some sort of response in tone.
« Last Edit: January 17, 2021, 05:49:14 PM by Muon »

Muon

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Re: Exercise intolerance - please help
« Reply #26 on: February 03, 2021, 04:22:42 PM »
Exercise-->Unknown source (Mast cells can release this)--> ^Mitochondrial DNA-->Microglia--->^IL-1b

Exosome-associated Mitochondrial DNA is Elevated in Patients with ME/CFS and Stimulates Human Cultured Microglia to Secrete IL-1b
« Last Edit: February 03, 2021, 05:23:12 PM by Muon »

Muon

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Re: Exercise intolerance - please help
« Reply #27 on: February 20, 2021, 09:26:12 AM »
Exercise-associated ROS (Reactive Oxygen species) production?

Does the Bleach trigger indicate that the body got problems with detoxification and thus having trouble with clearing exercise-induced ROS? Or cytokine ratios might be off, exercise affects these ratios.

https://poiscenter.com/forums/index.php?topic=3721.0
« Last Edit: February 20, 2021, 09:55:51 AM by Muon »

Muon

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Re: Exercise intolerance - please help
« Reply #28 on: February 22, 2021, 04:00:32 PM »

berlin1984

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Re: Exercise intolerance - please help
« Reply #29 on: July 29, 2021, 03:38:55 PM »
There are lists of supplements on the internet that can help, e.g. creatine gives you a buffer so you can do more. Sodium bicarbonate is also mentioned.

Other interesting thing:
https://med.virginia.edu/ginutrition/wp-content/uploads/sites/199/2014/06/Parrish-March-17.pdf
Lactic Acidosis: A Lesser Known Side Effect of Thiamine Deficiency