Author Topic: Testosterone  (Read 344472 times)

demografx

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Re: Testosterone
« Reply #160 on: January 29, 2016, 01:55:01 AM »
"The Vagus Nerve and Hormones"
From http://selfhacked.com/2015/07/30/28-ways-to-stimulate-your-vagus-nerve-and-all-you-need-to-know-about-it/#The_Vagus_Nerve_and_Hormones

"The vagus nerve is important for releasing testosterone.  If it’s not working well, it could be a reason for low testosterone.

Testosterone can make people more aggressive, but this is not the case when the vagus nerve is functioning right.

The vagus nerve can help reduce pain and this is the mechanism by which estradiol reduces pain in certain circumstances."


« Last Edit: January 29, 2016, 01:56:57 AM by demografx »
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

demografx

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Re: Testosterone
« Reply #161 on: February 17, 2016, 10:09:36 PM »
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

demografx

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Re: Testosterone
« Reply #162 on: February 23, 2016, 01:57:28 PM »

Cross-posted from thread: "Any suggestion for Doctor visit in London?"

From your research and experience with TRT do you think TRT affects fertility drastically?

Yes.

But that's just my experience and opinion. Talk to a good endocrinologist. Mine told me that TRT infertility can be reversed. I have 2 grown offspring so it's not an issue for me (personally) any longer.
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

brainfogfun

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Re: Testosterone
« Reply #163 on: March 02, 2016, 01:52:58 PM »
Hey everyone. I'm new to the form. I have been suffering from POIS for 7 years now, ever since I turned 18. It started with anxiety and depression and I've also had fibromyalgia/chronic fatigue for most of that time. Full list of symptoms: http://imgur.com/eoy9LjO

For a while I thought I just had a porn problem but upon experiencing bad brain fog after a nocturnal emission after a month or two of abstaining, I knew there had to be a problem outside of porn addiction.

I have tried every supplement known to man. For a while I thought my problems were from a lack of dopamine. Thinking maybe all my dopamine dropped off after O and was converted into prolactin or some other chemical. So I decided to try natural L-dopa. (mucuna pruriens) It helped me greatly.

I also started using a hormone balancing herb called "myomin" I found on amazon. It is supposed to get rid of bad estrogen and possibly increase testosterone. I stupidly took a bunch of supplements at the same time so I don't know which was doing what but I have narrowed it down to these two supplements.

It's possible I was just getting a 'high' from the mucuna but all my issues were pretty much gone. The change was drastic. I felt like everything was fixed and I felt amazing. I had bad days when I felt shitty again but for a bout a month or two I was feeling normal on some days which I haven't felt in so long. If I had an O, I would feel a little crumby the next day but after taking my supplements I felt better. Eventually I started feeling shitty all the time again but I think it might be because I went off the myomin and possible inconsistent quality of the mucuna. Also, something about winter seems to make my issues much worse.

So I thought my issues were all from a dopamine problem so I got put on pharmacy L-dopa for restless legs and it didn't really seem to do anything. So I looked up the other mechanisms of mucuna pruriens. It turns out it effects hormones and testosterone as well. There is evidence it can improve testosterone, sperm quality and hypothalamus, pituitary, adrenal, function.

Between the myomin and mucuna, this tells me that I was changing my hormone function, which is probably the cause of all my problems.

I got a blood test for all the standard hormone stuff from my doctor and he said everything was fine. However, my body and brain are telling me a very different story.

I have re-ordered the myomin and mucuna to try and improve what ever problems were being fixed before. I will let you guys know how it goes.

(So my current theory is that I have too much or too little of one or more hormones. Most likely something that comes from the hypothalamus, pituitary, adrenal axis, or thyroid. I think if we can correct the imbalance we can feel more or less normal. It's possible we have serotonin, dopamine, etc issue but I don't think that is the main problem, as I'm on anti depressants and they don't seem to be treating the right problem.)

(I have also had relief from maca, another hormone balancing herb, however it only works when abstaining for me. If I use it the day after an O it seems to make things worse. However I feel it is another clue to what is going on with me. The fact that it effects hormones tells me something is going on in that department.)


_____________________________________________________________________________


Here is some other research I have done on the HPA axis and hormone issues.

 In my research something that I keep coming back to dysfunction of the hypothalamic pituitary adrenal axis.

"We reviewed previous studies that have described an association between abnormal functioning of the hypothalamic-pituitary-adrenal axis and depression. In addition to melancholic depression, a spectrum of conditions may be associated with increased and prolonged activation of the hypothalamic-pituitary-adrenal axis. In contrast another group of states is characterized by hypoactivation of the stress system, rather than sustained activation, in which chronically reduced secretion of corticotropin releasing factor may result in pathological hypoarousal and an enhanced hypothalamic-pituitary-adrenal negative feedback. Patients with atypical depression, seasonal affective disorder and chronic fatigue syndrome fall in this category." -

http://www.scielo.br/scielo.php?pid=s1516-44462007000500005&script=sci_arttext&tlng=en

In my case I have had trouble finding if my symptoms were coming from hyper-activation or hypo-activation of the HPA axis. The aforementioned findings implicate decreased HPA axis activity in the S.A.D., chronic fatigue, and atypical depression. CRH is the first in the cascade of hormones in the HPA axis. If mine were to be low it would cause issues with acth > cortisol.

"Lack of the hormone CRH also results in the feelings of extreme tiredness common to people suffering from chronic fatigue syndrome. Lack of CRH is also central to seasonal affective disorder (SAD), the feelings of fatigue and depression that plague some patients during winter months."

"Significant levels of chronic ACTH autoantibodies are a common pathological factor in CFS, AN and MD. These antibodies interfere with ACTH's ability to stimulate the production and secretion of cortisol, causing HPA dysregulation. As a result, patients suffer from the symptoms of adrenocortical insufficiency and the side effects of overactive cortisol-stimulating mechanisms utilized to compensate for this interference."
« Last Edit: March 02, 2016, 02:08:15 PM by brainfogfun »

demografx

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Re: Testosterone
« Reply #164 on: March 23, 2016, 12:02:13 AM »


Successfully renewed today: $90 with insurance ($1,440 without)...3 months' Rx.

PLEASE UNDERSTAND THAT I AM NOT PROMOTING TESTOSTERONE FOR POIS.

NO RESEARCH HAS BEEN DONE.

I'M JUST SHARING MY PARTICULAR EXPERIENCE ON THIS THREAD.

Best wishes to everyone for finding YOUR particular POIS treatment.


« Last Edit: April 12, 2016, 03:03:23 PM by demografx »
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

b_jim

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Re: Testosterone
« Reply #165 on: March 24, 2016, 02:59:28 AM »
I really likethe idea that FREE TESTOSTERONE is more important than total testosterone for Pois.
 We have study showing total testosterone is not influenced by ejaculation, but what about free testosterone ?
Taurine = Anti-Pois
Lyme disease "cured" in 2020.

COLM_2

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Re: Testosterone
« Reply #166 on: March 24, 2016, 08:24:58 AM »


Successfully renewed today: $90 with insurance ($1,440 without)...3 months' Rx.

PLEASE UNDERSTAND THAT I AM NOT PROMOTING TESTOSTERONE FOR POIS. NO RESEARCH HAS BEEN DONE. I'M JUST SHARING MY PARTICULAR EXPERIENCE ON THIS THREAD.

Best wishes to everyone for finding YOUR particular POIS treatment.

Good news for you Demo ! Happy days !!
Colm
Formerly user COLM (previous username accidentally deleted). Few decades with POIS.

demografx

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Re: Testosterone
« Reply #167 on: March 24, 2016, 01:50:12 PM »
Many thanks, Colm!

And back to you as well!

:)
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

demografx

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Re: Testosterone
« Reply #168 on: March 24, 2016, 03:42:15 PM »
I really likethe idea that FREE TESTOSTERONE is more important than total testosterone for Pois.
 We have study showing total testosterone is not influenced by ejaculation, but what about free testosterone ?
Interesting question, b_jim.
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

demografx

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Re: Testosterone
« Reply #169 on: March 28, 2016, 11:30:26 PM »
From drugs.com forum: "How long does one [testosterone] patch last?"
http://www.drugs.com/answers/androderm-long-patch-2944531.html
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

demografx

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Re: Testosterone
« Reply #170 on: March 31, 2016, 10:43:25 PM »



Even after several years' TRT treatment, I found the above article useful, especially about confirming (for me) that in the evening (the blog author sez "10:00pm") is the ideal time to apply patches.



« Last Edit: April 12, 2016, 03:48:34 PM by demografx »
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

demografx

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Re: Testosterone
« Reply #171 on: April 17, 2016, 09:35:15 PM »
I think it has been written here (and sourced) that at the very beginning of the POIS cycle there is a massive drop in testosterone. I believe this, so I apply a LARGE dose of testosterone as soon as POIS begins, then taper off. I'm not sure my doctor would like what I'm doing, but, like so much of our POIS life, lacking real POIS experts "out there"...we all seem to make some independent decisions.


« Last Edit: April 17, 2016, 09:38:05 PM by demografx »
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

FloppyBanana

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Re: Testosterone
« Reply #172 on: April 21, 2016, 04:59:30 PM »
FYI - Testosterone link to heart attacks in men, say Edinburgh researchers

http://www.bbc.co.uk/news/uk-scotland-edinburgh-east-fife-36100525
30 years of POIS. Mytelase after O with Iceman breathing technique.

demografx

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Re: Testosterone
« Reply #173 on: April 21, 2016, 05:20:21 PM »
FB, well placed and interesting article: I had a quintuple coronary bypass, and TRT does not please my physician with the cardiac risks of TRT, but at least he understands that I need TRT for my POIS.
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

demografx

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Re: Testosterone
« Reply #174 on: April 26, 2016, 09:44:40 PM »
Some bodybuilders abuse testosterone with excessive amounts - supraphysiologic steroid levels -  to gain muscle mass.

I wonder how much of the cardiac problems can be attributed to that.

The bodybuilder photo at the beginning of the article below reminded me of a similar conversation I had with my endocrinologist.


FYI - Testosterone link to heart attacks in men, say Edinburgh researchers

http://www.bbc.co.uk/news/uk-scotland-edinburgh-east-fife-36100525



« Last Edit: April 27, 2016, 12:20:21 PM by demografx »
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

joelawerence

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Re: Testosterone
« Reply #175 on: May 17, 2016, 08:22:23 AM »
I thought I will brief my recent test results:

I met my GP for the first time last month with my private blood results taken in Oct last year. That private blood test indicated I had very low testosterone of 3.0 (minimum threshold of 8.0), high cholesterol, high liver enzymes and high TSH (Thyroid stimulating hormone). I showed him the test results and said to him that I am fatigued most of the time and have muscle pains, loss in concentration, etc. but did not mention about the connection with orgasm. He then had me take blood tests again in the public hospital for Testosterone, liver enzymes, thyroid and Fasting glucose (Diabetes).

The results from this blood test are:
Testosterone : Very low - 5.8 (minimum threshold of 8.0) although increased from last time because I took this test in the morning as overnight fasting was needed for the glucose test
Blood Glucose : High - 7.0 (max threshold of 6.0 for fasting)
Liver enzymes : High (dont know the values)
Thyroid : Normal (dont know the values)

For some reason my GP seemed more concerned about my high liver enzymes that the low testosterone or high glucose. Anyways he has asked me to come back in 2 months to re-do these tests to see any fluctuations. In these two months I am planning to reduce my orgasm frequency (from my current once every 3-4 days to once a week or less) and start moderate daily exercising as I have felt exercising and doing aerobic sports greatly helped with my POIS. I hope that this will help increase my testosterone which is also related to Blood Glucose apparently from my research.

I will report back the results of that test in a couple of months.

My details - Age: 30 yrs, have had POIS for around 9-10 years.
« Last Edit: May 17, 2016, 11:22:57 AM by joelawerence »
33 years old, POIS for around 12 years with increasing severity.
Major symptoms - Severe fatigue, back pain, unrefreshed even after 9+ hours sleep, pain behind eyes, very dry face, bald head with inflamed scalp, digestion issues and constipation. Very low testosterone and high glucose in blood tests

Quantum

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Re: Testosterone
« Reply #176 on: May 17, 2016, 09:15:48 AM »

For some reason my GP seemed more concerned about my high liver enzymes that the low testosterone or high glucose. Anyways he has asked me to come back in 2 months to re-do these tests to see any fluctuations. In these two months I am planning to reduce my orgasm frequency (from my current once every 3-4 days to once a week or less) and start moderate daily exercising as I have felt exercising and doing aerobic sports greatly helped with my POIS. I hope that this will help increase my testosterone which is also related to Blood Glucose apparently from my research.


Hi joelawerence,

I personally have a "sluggish" liver, meaning a certain level of chronic liver failure, even if not that high.  It seems to not be uncommon among POIS sufferers.  Here is a discussion we had about this:  http://poiscenter.com/forums/index.php?topic=555.msg17402#msg17402 .

In the following post, I share some of my strategies to help my liver cope better: http://poiscenter.com/forums/index.php?topic=555.msg17409#msg17409

In another (rather long) post, I gave some more detailed information at the end of the post, about how to help a sluggish liver.  This guy had elevated ALT, a liver enzyme.  As noted in the post, these suggestions are in no way replacing the advice of your doctor, and have to be discussed with him:  http://poiscenter.com/forums/index.php?topic=555.msg17409#msg17409

« Last Edit: May 17, 2016, 09:19:54 AM by Quantum »
You are 100% responsible for what you do with anything I post on this forum and of any consequence it could have for you.  Forum rule: ""Do not use POISCenter as a substitute for, or to give, medical advice" Read the remaining part at http://poiscenter.com/forums/index.php?topic=1.msg10259#msg10259

joelawerence

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Re: Testosterone
« Reply #177 on: May 19, 2016, 08:18:23 AM »

For some reason my GP seemed more concerned about my high liver enzymes that the low testosterone or high glucose. Anyways he has asked me to come back in 2 months to re-do these tests to see any fluctuations. In these two months I am planning to reduce my orgasm frequency (from my current once every 3-4 days to once a week or less) and start moderate daily exercising as I have felt exercising and doing aerobic sports greatly helped with my POIS. I hope that this will help increase my testosterone which is also related to Blood Glucose apparently from my research.


Hi joelawerence,

I personally have a "sluggish" liver, meaning a certain level of chronic liver failure, even if not that high.  It seems to not be uncommon among POIS sufferers.  Here is a discussion we had about this:  http://poiscenter.com/forums/index.php?topic=555.msg17402#msg17402 .

In the following post, I share some of my strategies to help my liver cope better: http://poiscenter.com/forums/index.php?topic=555.msg17409#msg17409

In another (rather long) post, I gave some more detailed information at the end of the post, about how to help a sluggish liver.  This guy had elevated ALT, a liver enzyme.  As noted in the post, these suggestions are in no way replacing the advice of your doctor, and have to be discussed with him:  http://poiscenter.com/forums/index.php?topic=555.msg17409#msg17409

Thanks Quantum for the post links. Have you ever measured your liver enzymes? If so, what were their values? I believe that my high liver enzymes figures are due to a mild inflammation of the liver due to POIS. I think POIS causes general inflammation in most organs of the body, atleast in my case.
33 years old, POIS for around 12 years with increasing severity.
Major symptoms - Severe fatigue, back pain, unrefreshed even after 9+ hours sleep, pain behind eyes, very dry face, bald head with inflamed scalp, digestion issues and constipation. Very low testosterone and high glucose in blood tests

demografx

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Re: Testosterone
« Reply #178 on: June 06, 2016, 10:42:54 PM »
I've been out of my patches-for-POIS for several days now, can't renew till 6/17. Wish me luck, it's in the doc's hands, not hoping for anything. I told my pharmacist I feel like a street junkie waiting for his fix. :)
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

demografx

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Re: Testosterone
« Reply #179 on: June 09, 2016, 01:53:14 AM »
I've been out of my patches-for-POIS for several days now, can't renew till 6/17. Wish me luck, it's in the doc's hands, not hoping for anything. I told my pharmacist I feel like a street junkie waiting for his fix. :)
Whoever is reading this must have sent me some

magic well wishing signals,



my renewal's just been approved - for today, 90 patches/$90 co-pay. Whew.

Your TRT addict,
demo

:)
« Last Edit: June 09, 2016, 01:57:03 AM by demografx »
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business