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Update: I've been taking taurine caps now for a couple weeks. I didn't notice mental benefits tbh.
My skin however is looking better than it has looked in a year. I'm looking younger. That's good.
I think it is related to taurine. But I'm not sure if it's taurine or other recently bought supplements like curcuma, or even ginseng.
Let me know your thoughts on taurine in connection with skin benefits.
Edit: Still having unexpectedly good effects on my skin. As far as what supplement is giving me those benefits, I'm starting to believe that it is actually NAC that I've been taking for a week now.
I'm glad that I found something to take when I have to/want to look my best.
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Hormonal Causes and Treatments / Re: Mast Cell Activation Syndrome
« Last post by Progecitor on February 18, 2024, 03:59:23 AM »
The beneficial effect of a mixture of aqueous extracts of eight herbs (chamomile, saffron, anise, fennel, caraway, licorice, cardamom, and black seed) was shown on inhibition of histamine
release from chemically or immunologically stimulated rat peritoneal mast cells. In addition, the clinical study showed a significant improving effect of the herbal tea on patients suffering
from allergic asthma (Haggag et al., 2003).

https://sci-hub.st/https://www.tandfonline.com/doi/abs/10.1080/10408390902773003
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I do not believe POIS is caused by over or under methylation. But I do believe POIS severely depletes the methylation cycle, which exacerbates ALL symptoms, especially mental symptoms.

I believe the root cause of POIS is some kind of infection, virus, pathogen, or gut microbiome problem.
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General POIS Discussions / Re: Do You Have Decreased Sexual Desire from POIS?
« Last post by Warrior on February 17, 2024, 01:49:36 AM »
Thomas - I also had/have an esoteric, spiritual belief system that tries to explain this lack of sexual energy, and I'm not totally sure how accurate or "real" it is. But I've been experimenting with Warrior's and Nanna1's supplement recommendations and they have helped a lot.

Supplements that have a very positive impact on sexuality and overall charisma:
- SAMe
- Vitamin B Complex
- I've also been on a decently strict diet of meat, organs, eggs, and fruit (following Paul Saladino's diet)

So I feel like this mostly comes down to POIS symptoms, although there may be *some* truth to the whole sexual energy thing. Right now I'm thinking undermethylation (for me it's definitely undermethylation, for others it might be over methylation) or like some type of faulty mechanism with the immune system (AKA autoimmune issues) is the true main culprit, which is why SAMe and B complex helps so much.

The results have been good so far, although I haven't jerked off in prob like 3-4 weeks now. My urgency in finally searching this stuff up was that symptoms were lasting far longer than the typical 1-2 weeks and I would still experience them at times into a very long abstinence period. Now, as soon as I take the SAMe my nuts feel heavy again and I feel more sexual.

I'm happy with the results and am very optimistic for the future. I plan to do Nanna1's immune recovery stack, which includes IV injections of Vitamin C like 3 days in a row, among other things. I think POIS is something we can heal for good but time will tell.

Other supplements I'm taking right now that I find helpful (although some I've just started). All of these I found recommended by either Warrior or Nanna1:
- Fish Oil
- Vitamin D + K2
- Alpha GPC
- TMG
- Glycine
- Vitamin C gummies
- Calcium

Side note, I'm also doing a parasite cleanse where I'm taking Ivermectin right now and I plan on doing a full protocol with Fenbendazole, Ivermectin, and Doxycycline. I think this has potential for healing some autoimmune issues. I'm a full on conspiracy theorist and have gotten into parasite theories (they cause cancer, most people have some version of them, etc.) So the parasite cleanse, the regular POIS supplements I'm taking now, and the future POIS autoimmune recovery protocol by Nanna1 are my 3 weapons so far in the battle against POIS.

Great to hear some of methylation supplements are working well for you.

Make sure you are getting adequate B12, folate, and B6. These co-factors are required for SAM-e to work properly.

And, make sure you are supplementing nutrients for the glycine buffer system. This will prevent over-methylation, which is likely to happen at some point when supplementing methyl groups (SAM-e, methyl B12, methylfolate, B6, choline, TMG, etc.) You can learn more about that here, but to summarise, these are the most important nutrients you must satisfy for the buffer system to work properly:
--Glycine 3-9g
--Vitamin A
--Folate
--Riboflavin
--Adequate iron (I have to supplement as my iron levels are low. You may not need to. I take iron biglycinate.)

The purpose of the glycine buffer system is to buffer excess methyl groups that you've taken in, but which you don't currently need. When the buffer system does not work properly and you're taking in more methyl groups than you need / can handle, you will experience symptoms of over-methylation, which I believe also causes POIS symptoms. The buffer system also helps to retrieve methyl groups when you need them.
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General POIS Discussions / Re: Do You Have Decreased Sexual Desire from POIS?
« Last post by Jackmerius on February 16, 2024, 10:50:14 PM »
Thomas - I also had/have an esoteric, spiritual belief system that tries to explain this lack of sexual energy, and I'm not totally sure how accurate or "real" it is. But I've been experimenting with Warrior's and Nanna1's supplement recommendations and they have helped a lot.

Supplements that have a very positive impact on sexuality and overall charisma:
- SAMe
- Vitamin B Complex
- I've also been on a decently strict diet of meat, organs, eggs, and fruit (following Paul Saladino's diet)

So I feel like this mostly comes down to POIS symptoms, although there may be *some* truth to the whole sexual energy thing. Right now I'm thinking undermethylation (for me it's definitely undermethylation, for others it might be over methylation) or like some type of faulty mechanism with the immune system (AKA autoimmune issues) is the true main culprit, which is why SAMe and B complex helps so much.

The results have been good so far, although I haven't jerked off in prob like 3-4 weeks now. My urgency in finally searching this stuff up was that symptoms were lasting far longer than the typical 1-2 weeks and I would still experience them at times into a very long abstinence period. Now, as soon as I take the SAMe my nuts feel heavy again and I feel more sexual.

I'm happy with the results and am very optimistic for the future. I plan to do Nanna1's immune recovery stack, which includes IV injections of Vitamin C like 3 days in a row, among other things. I think POIS is something we can heal for good but time will tell.

Other supplements I'm taking right now that I find helpful (although some I've just started). All of these I found recommended by either Warrior or Nanna1:
- Fish Oil
- Vitamin D + K2
- Alpha GPC
- TMG
- Glycine
- Vitamin C gummies
- Calcium

Side note, I'm also doing a parasite cleanse where I'm taking Ivermectin right now and I plan on doing a full protocol with Fenbendazole, Ivermectin, and Doxycycline. I think this has potential for healing some autoimmune issues. I'm a full on conspiracy theorist and have gotten into parasite theories (they cause cancer, most people have some version of them, etc.) So the parasite cleanse, the regular POIS supplements I'm taking now, and the future POIS autoimmune recovery protocol by Nanna1 are my 3 weapons so far in the battle against POIS.
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Introduction, Forum Rules and Admins Messages / Re: Admin Corner
« Last post by demografx on February 16, 2024, 12:58:02 PM »

Click here
View the most recent posts on the forum.

Please bookmark this. You’ll thank us :)

I always start here to find out what’s going on at the Forum!
Demo

https://tinyurl.com/yy97dfue
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Articles, References and Links / Re: POIS paper treatment summary
« Last post by Progecitor on February 16, 2024, 10:22:54 AM »
https://poiscenter.com/forums/index.php?topic=2822.msg47997#msg47997
Tonicard capsul
Biosan tablet
Starfer capsul
Q10 100

It is probably more understandable this way.

Tonicard [Rd:1]: Supplements to help maintain body health.
Ubidecarenone (also Coenzyme Q10) 100 mg
L-carnitine 500 mg
Vitamin E 100 IU
Folic acid 800 ug

Biosan [Rd:3]: It helps to improve sperm quality and quantity.
Tribulus terrestris L – 275 mg

Starfer [Rd:2]: It helps to maintain healthy prostate function.
Pygeum africanum extract – 100.0 mg
Zinc sulfate – 20.0 mg
Piridoxine – 1.0 mg
Folic acid – 100.0 ug
Ascornic acid – 30.0 mg
Cyanocobalamin – 0.5 ug
Fructose – 104.0 mg
Sodium Selenite – 0.02 mg
Arginine – 50.0 mg
Carnitine – 40.0 mg
Vitamin E – 5.0 mg
Microcrystalline Cellulose - 100.0 mg

Coenzyme Q10 100 mg
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February 16th
Planned Masturbation without significant influence. I experienced mild brain fog and dizziness, as well as obvious exhaustion. However, fortunately, my language skills were not impaired as they were before, and the decrease in willpower was somewhat alleviated, perhaps due to the 12-day period of abstaining. During the abstinence period, I slightly perceived a withdrawal reaction that made life seem duller, but the gradual recovery of mental abilities made me realize that it was worth it. According to the rules I set for myself, the next time I will ejaculate will be on March 5th.
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Articles, References and Links / Re: POIS paper treatment summary
« Last post by Muon on February 16, 2024, 04:59:33 AM »
https://poiscenter.com/forums/index.php?topic=2822.msg47997#msg47997
Tonicard capsul
Biosan tablet
Starfer capsul
Q10 100
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Hormonal Causes and Treatments / Re: Clomid instead of TRT
« Last post by anson123 on February 16, 2024, 04:05:32 AM »
these are the supplements i got, hope it can be helpful. thanks
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