Recent Posts

31

POIS Research / Re: POIS NORD RESEARCH STUDY

« Last post by demografx on November 29, 2024, 12:30:57 PM »

Are the researchers also gonna look into possible gene therapy?  I see that NORD is specialised in this...

I’ll ask, Aladin.

32

General Alternative Causes and Treatments of POIS / Re: Thiamine Megadoses (Vitamin B1) and Thiamine Analogs

« Last post by demografx on November 29, 2024, 12:30:03 PM »

1995 animal study showed that taurine helps with normal level restauration of a form of thiamine (phosphate esters ) after its depletion by drug.

I think the combination of taurine + (benfo)thiamine will be my strategy  for 2025.

Fascinating, b_jim! Your research with taurine goes way back to our predecessor-forum beginnings in 2007!

33

General POIS Discussions / Re: WHATSAPP GROUP FOR BRAZILIANS

« Last post by demografx on November 29, 2024, 12:28:04 PM »

Nice!
I think now we should have groups in 4 continents already (N-A, S-A, Europe, Asia).

Amazing, Berlin!

34

General Alternative Causes and Treatments of POIS / Re: Thiamine Megadoses (Vitamin B1) and Thiamine Analogs

« Last post by b_jim on November 29, 2024, 07:44:41 AM »

1995 animal study showed that taurine helps with normal level restauration of a form of thiamine (phosphate esters ) after its depletion by drug.

I think the combination of taurine + (benfo)thiamine will be my strategy  for 2025.

35

POIS Research / Re: POIS NORD RESEARCH STUDY

« Last post by Aladin on November 29, 2024, 06:24:50 AM »

Are the researchers also gonna look into possible gene therapy?  I see that NORD is specialised in this...

36

General POIS Discussions / Gene therapy

« Last post by Aladin on November 29, 2024, 06:21:41 AM »

Has anybody ever introduced the idea of gene therapy?

Are the NORD researchers planning to study the genes of the participants in their project?

37

General POIS Discussions / Re: WHATSAPP GROUP FOR BRAZILIANS

« Last post by berlin1984 on November 29, 2024, 02:23:13 AM »

Nice!
I think now we should have groups in 4 continents already (N-A, S-A, Europe, Asia).

38

General POIS Discussions / WHATSAPP GROUP FOR BRAZILIANS

« Last post by Robson on November 28, 2024, 07:48:28 PM »

Today, November 28, 2024, I am posting my WhatsApp number (48991405838) so that you, who are also Brazilian, can join me so that we can create a discussion group about what we can do to give more visibility to this syndrome, as well as to demand that public institutions and health professionals recognize that the syndrome exists and that they need to be committed to researching and supporting us, just as other countries have already recognized and are committed to doing.

So, that's the idea! If we want a solution to our problems, we must unite, in a group of Brazilians with the same symptoms, so that together we can have some idea of ??how to give more visibility to this, as well as demand recognition by the authorities.

By this, I mean that as long as time passes, it will be okay. If you saw this post, send me a message to this number (48991405838) saying simply: ""Hello! P.O.I.S", and I will respond to you.

I'll be waiting!

39

Poll Center / Re: Neutrophils

« Last post by Hopeoneday on November 28, 2024, 06:06:50 PM »

On medical test results topic:
I found 13 from 14 hawe neutropenia or low end neutrophils count.
Found 9 others who reported low white blood cells.

From thouse 9 who reported low white blood cells,
i can bet 99% of them are low neutrophil count, neutropenia.

Exemple, result 3,6 from range 3,5-7 is considered in range,
normall, but actualy it is not normall to hawe lower end neutrophils
count.
This neutrophils count data talk something to us, it is repeating in
poisers.

40

POIS Research / Re: Gather and Post Here Your Medical Tests Results

« Last post by Hopeoneday on November 28, 2024, 05:25:46 PM »

Another poiser with neutropenia, lower end neutrophils count.

- Year of Birth: 2002
- Gender/Age: Male / 22 years
- Test Date: 2024-07-09

## CRP Test (Quantitative) - SERUM
- Result: < 1.0 mg/l
- Reference Range: 0 - 5 mg/l
- Status: Normal

## Total IgE - SERUM
- Result: 62 IU/ml
- Reference Range: Up to 100 IU/ml
- Status: Normal

## RF Test (Quantitative) - SERUM
- Result: < 20.0 IU/ml
- Reference Range: Up to 30 IU/ml
- Status: Normal

## Complete Blood Count (CBC) with Reticulocytes and Manual Differential - VENOUS BLOOD (EDTA)

### Red Blood Cell Parameters
- Erythrocytes: 4.73 million/?l (Reference: 4.5 - 5.
- Hemoglobin: 14.2 g/dl (Reference: 13.5 - 17)
- Hematocrit: 41.8% (Reference: 40 - 53)
- MCV: 88.4 fl (Reference: 82 - 100)
- MCH: 30.0 pg (Reference: 27 - 31)
- MCHC: 34.0 g/dl (Reference: 31 - 36)
- RDW-CV: 12.8% (Reference: 11.5 - 14)
- RDW-SD: 41.4 fl (Reference: 37 - 50)

### White Blood Cell Parameters
- Leukocytes: 5.10 thousand/?l (Reference: 4.5 - 10.5)
- Neutrophils: 54.5% / 2.78 thousand/?l (Reference: 50-70% / 2.7-6.5)
- Eosinophils: 4.3% / 0.22 thousand/?l (Reference: 1-5% / 0.1-0.5)
- Basophils: 0.4% / 0.02 thousand/?l (Reference: 0-1% / 0-0.1)
- Lymphocytes: 32.2% / 1.64 thousand/?l (Reference: 25-45% / 1.5-3.7)
- Monocytes: 8.4% / 0.43 thousand/?l (Reference: 1-12% / 0.2-0.9)
- Immature Granulocytes: 0.2% / 0.01 thousand/?l (Reference: 0-2.5% / 0-0.03)

### Platelet Parameters
- Platelets: 304 thousand/?l (Reference: 150 - 400)
- PCT: 0.33% (Reference: 0.2 - 0.5)
- MPV: 10.9 fl (Reference: 8 - 12)
- PDW: 13.8% (Reference: 8 - 18)
- P-LCR: 32.8% (Reference: 13 - 43)

### Reticulocytes
- Reticulocytes #: 0.0582 10^6/?l (Reference: 0.02 - 0.1)
- Reticulocytes %: 1.23% (Reference: 0.5 - 2)
- IRF%: 7.3% (Reference: 2 - 17)
- RET-He: 32.8 pg (Reference: 28 - 35)

## Full Liver Panel - SERUM

### Autoantibody Tests
- ANA (IIF): NEGATIVE
  - No antinuclear and anticytoplasmic antibodies detected at 1:100 dilution
- Anti-Smooth Muscle Antibodies (ASMA): NEGATIVE
- Anti-Mitochondrial Antibodies (AMA): NEGATIVE
- Anti-Liver Kidney Microsomal Antibodies (anti-LKM): NEGATIVE
  - No AMA, ASMA, anti-LKM antibodies detected in IgG class at 1:100 dilution