Wow, I have to say I didn't expect it to work, but it did, and it was a massive success. If I wasn't required to take it before each orgasm, I'd even call it the ultimate cure for POIS.
For my trial, I used Rhinathiol Promethazine (liquid), with a dosage of 7.5mL to 10mL. Luckily, it's available at any pharmacy in my area without a prescription for as little as $2 USD.
My main POIS symptoms are both cognitive and physical: brain fog, short-term memory loss, intense fatigue, and inflammation lasting for about 3 days.
I took my first dose on August 9th, and an hour later I had an orgasm. And like you said, 0 POIS symptoms. The following day, I felt the physical symptoms, but they were minimal, only about 25% of the usual pain. And they only last for 2 days but I wasn't really feeling it that much compared to the usual pois. I suspect this might be partly due to my poor physical health, as POIS has kept me from working out and eating healthy for years. I imagine that with a regular workout routine, along with fenugreek and beetroot, the physical symptoms would cease to exist.
The best part is my brain functions remains fully intact, and it stays like that permanently, no time limits. No more waking up the next day post orgasm wondering what I did yesterday. It really feels like a protective shield for my brain. I've even returned to work at full performance after years of being on hiatus.
In my case, when I take it even 5 mins post orgasm, it won't work. It has to be explicitly 45-60 mins before orgasm. I still orgasmed like two or three times it still wouldn't make a difference in my symptoms, which is most impressive. even if I delayed my orgasm like 80-100 mins after my dose it would still work.
I've tried Niacin in the past, but it only managed to alleviate the physical symptoms. I still struggled with brain fog, and it was challenging to stay in a flushed state for it to work.
But with Promethazine, you just take the dose, wait an hour, and that's it. I do still experience an intense headache about three hours after the dose, lasting for two hours. I found that taking more than 8mL causes intense anxiety and headache, even when taken at night, it can still make sleeping super hard for a few hours. So I found my sweetspot to be 7.5mL, your mileage may vary.
This has genuinely transformed my life and perspective. After years of suffering, I can finally live POIS-free. I no longer have to worry about the symptoms, which used to hinder every aspect of my life.
I'm now even more curious about how it actually works to prevent my symptoms. How did you come to the conclusion that this might work?was it advice from a doctor or something you discovered through research?
I've been taking it for 3 weeks now, (I orgasm 3-4 times each week, so that's 3-4 doses) I've waited this long before posting to verify that it is not some placebo effect. No issues so far.
I'll never forget this post, and your name, Mike. From the bottom of my heart, thank you
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