Author Topic: Clues' case so far  (Read 6401 times)

Clues

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Re: Clues' case so far
« Reply #20 on: November 04, 2021, 09:13:03 AM »
BoneBroth, correction: Based on some recent experiences, I think I do get symptoms from arousal after all, just not as bad as after orgasm.

I've had a couple of occasions recently where I've been making out and highly aroused for a long time, say a few hours, but avoided orgasm specifically because I had some job interviews coming up. However, on these occasions I definitely had somewhat stronger symptoms than my "background" symptom level the day after. Weaker than post-orgasm symptoms both in duration and severity, but definitely present.

BoneBroth

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Re: Clues' case so far
« Reply #21 on: November 04, 2021, 03:05:55 PM »
Ok, my "arosal" effects became more intense over the years and finally only one single erotic thought could cause severe POIS headache for 24 hours! However, my body seems to have potential to build up an "arosal resistance" again under certain conditions. My POIS-sensitivity can go back and forward depending on things I do not yet fully understand, but I correlate the things below to the better periods:

  • Most important: Pausing from O/NE for long time (1-3 months).
  • Decrease stress. Relaxing activities (vacation, meeting people I like and avoiding those I dont like).
  • When my gut/intestines are better (no smelly gas, better consistance of the poop etcetera). Eating less FODMAP.
  • When there is less white coating on my tounge (candida?). The coating decreases when I avoid sugar and eat things like oregano oil/pau'darco tea and foods that is hight in pH
  • Taking much of vitamin C equally distributed during the day (total of about 3 grams/day)
  • Have a good sleep
  • Some of my other supplements might have a noticeable effect, but I'm not sure what or in what combination: Liver detox/chlorella, B/D/A-vitamins, zink, magnesium, collagen, Nanna1's POIS stack, aloe vera, msm, sodium bicarbonate, hemp protein, curcumin/ginger/black pepper capsules etc.

This made me think that POIS is close related to stress and the condition in the intestines (whitch depends on stress and food). Frequent O/NE is consuming lots of raw materials for hormones and those hormones are deprived on stress/low intestinal nutritional uptake. Further, the following POIS inflammation is consuming even more of the hormon cortisol and hight cortisol might itself be the cause of half of the POIS-symptoms. So POIS might be a combination of stress and orgasm (I was bullied for 9 years in school, when I developed POIS and that completely destroyed a normal life).
« Last Edit: November 04, 2021, 03:20:25 PM by BoneBroth »

BoneBroth

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Re: Clues' case so far
« Reply #22 on: November 10, 2021, 10:34:08 AM »
Thanks for postning your latest analyse report. interesting that it also recommends you to do a SIBO test. I havn't read th ereport in detail but you seems to have high beta-glucuronidase? Found some info on that here.

Clues

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Re: Clues' case so far
« Reply #23 on: November 10, 2021, 12:07:40 PM »
No problem BoneBroth. Here is the report in case anyone else wants to check it out.

Yeah my beta-glucuronidase is well above the reference range at 8111 U/g. The reference range is 368-6266 U/g. Thanks for the link on that, I'll have a look.

Btw I remember you suggested SIBO before as a thing I should check out. Maybe it's time to take that test as well. Curious how many false positives there are in SIBO testing, does anyone know?

BoneBroth

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Re: Clues' case so far
« Reply #24 on: November 10, 2021, 12:14:50 PM »
In a month I will recieve and possible put here a similar advanced report as yours. Christmas comes early this year!

Clues

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Re: Clues' case so far
« Reply #25 on: December 12, 2021, 01:25:12 PM »
Tested positive for SIBO. Details here.

Lihua

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Re: Clues' case so far
« Reply #26 on: January 23, 2022, 08:10:46 AM »
Tested positive for SIBO. Details here.
hello Clues, do you begin to handle the SIBO?
A Chinese man undergoing desenz from 2021.8 to 2022.2, it became worse from 1.5 to 4.5 days, do not know it is spontaneous deterioration or by desenz. Believe POIS is a kind of immune diseases. My case:https://poiscenter.com/forums/index.php?topic=4104.0

Clues

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Re: Clues' case so far
« Reply #27 on: January 24, 2022, 01:39:51 PM »
Tested positive for SIBO. Details here.
hello Clues, do you begin to handle the SIBO?

Hi Lihua. Yes, I recently finished a one-month SIBO cure using Candibactin-AR and Berberine. Unfortunately there was no noticeable improvement.

In about three weeks I'm going to try a fecal transplant with a private clinic here in Norway. They have a lot of experience with the procedure and seem to know what they're doing. It's quite expensive, at about 25000 NOK in total. If that fails, I don't know what else I can try to alleviate my gut issues, so fingers crossed.

Lihua

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Re: Clues' case so far
« Reply #28 on: January 24, 2022, 07:48:43 PM »
Tested positive for SIBO. Details here.
hello Clues, do you begin to handle the SIBO?

Hi Lihua. Yes, I recently finished a one-month SIBO cure using Candibactin-AR and Berberine. Unfortunately there was no noticeable improvement.

In about three weeks I'm going to try a fecal transplant with a private clinic here in Norway. They have a lot of experience with the procedure and seem to know what they're doing. It's quite expensive, at about 25000 NOK in total. If that fails, I don't know what else I can try to alleviate my gut issues, so fingers crossed.
fine, I saw Rifaximin can help a lot of people, did you ask your doctor prescribe it for you? If you have, why did not your doctor prescribe it?
« Last Edit: January 24, 2022, 07:57:52 PM by Lihua »
A Chinese man undergoing desenz from 2021.8 to 2022.2, it became worse from 1.5 to 4.5 days, do not know it is spontaneous deterioration or by desenz. Believe POIS is a kind of immune diseases. My case:https://poiscenter.com/forums/index.php?topic=4104.0

Clues

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Re: Clues' case so far
« Reply #29 on: January 28, 2022, 01:31:44 PM »
Lihua, the treatment I tried has been proven to be as effective as antibiotics against SIBO.

Antibiotics seems like a bad idea in my case as my gut microbiome is not healthy. A recent test failed to detect an important bacterium. There were other problems as well. Personally I think a fecal transplant has a much higher chance of success in my case.

Lihua

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Re: Clues' case so far
« Reply #30 on: January 30, 2022, 04:52:30 AM »
Lihua, the treatment I tried has been proven to be as effective as antibiotics against SIBO.

Antibiotics seems like a bad idea in my case as my gut microbiome is not healthy. A recent test failed to detect an important bacterium. There were other problems as well. Personally I think a fecal transplant has a much higher chance of success in my case.
hello, maybe you should take [My experience: I take] probiotic like me, such as Bifidobacterium etc
« Last Edit: January 31, 2022, 04:10:03 AM by demografx »
A Chinese man undergoing desenz from 2021.8 to 2022.2, it became worse from 1.5 to 4.5 days, do not know it is spontaneous deterioration or by desenz. Believe POIS is a kind of immune diseases. My case:https://poiscenter.com/forums/index.php?topic=4104.0

demografx

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Re: Clues' case so far
« Reply #31 on: January 31, 2022, 09:50:04 PM »
Lihua, the treatment I tried has been proven to be as effective as antibiotics against SIBO.

Antibiotics seems like a bad idea in my case as my gut microbiome is not healthy. A recent test failed to detect an important bacterium. There were other problems as well. Personally I think a fecal transplant has a much higher chance of success in my case.
hello, maybe you should take [My experience: I take] probiotic like me, such as Bifidobacterium etc

mod edit - Demo
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

Clues

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Re: Clues' case so far
« Reply #32 on: February 12, 2022, 09:22:55 AM »
Lihua, most probiotics on the market are not scientifically proven to help, and may in fact make your gut microbiome worse. What's a good and what's a bad balance in the gut microbiome is currently uncertain even at the cutting edge of science, according to two doctors I've spoken to, both specialised in gut health and the gut microbiome. So it's best to stick with specific probiotica products that have solid science behind them IMHO.

However a lot of gut bacteria can't even survive in a capsule AFAIK. So it's likely that not every gut microbiome problem can be solved with probiotica anyway, as I understand it.

I'm going to try a fecal transplant in a month's time, as I think in my case my gut microbiome is badly messed up due to way too much antibiotics in my childhood and young adult life. Will post about the results.

Lihua

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Re: Clues' case so far
« Reply #33 on: February 12, 2022, 09:57:54 PM »
Lihua, most probiotics on the market are not scientifically proven to help, and may in fact make your gut microbiome worse. What's a good and what's a bad balance in the gut microbiome is currently uncertain even at the cutting edge of science, according to two doctors I've spoken to, both specialised in gut health and the gut microbiome. So it's best to stick with specific probiotica products that have solid science behind them IMHO.

However a lot of gut bacteria can't even survive in a capsule AFAIK. So it's likely that not every gut microbiome problem can be solved with probiotica anyway, as I understand it.

I'm going to try a fecal transplant in a month's time, as I think in my case my gut microbiome is badly messed up due to way too much antibiotics in my childhood and young adult life. Will post about the results.
hope fecal transplant will help you. God bless you
A Chinese man undergoing desenz from 2021.8 to 2022.2, it became worse from 1.5 to 4.5 days, do not know it is spontaneous deterioration or by desenz. Believe POIS is a kind of immune diseases. My case:https://poiscenter.com/forums/index.php?topic=4104.0

Lihua

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Re: Clues' case so far
« Reply #34 on: February 13, 2022, 03:12:33 AM »
Lihua, most probiotics on the market are not scientifically proven to help, and may in fact make your gut microbiome worse. What's a good and what's a bad balance in the gut microbiome is currently uncertain even at the cutting edge of science, according to two doctors I've spoken to, both specialised in gut health and the gut microbiome. So it's best to stick with specific probiotica products that have solid science behind them IMHO.

However a lot of gut bacteria can't even survive in a capsule AFAIK. So it's likely that not every gut microbiome problem can be solved with probiotica anyway, as I understand it.

I'm going to try a fecal transplant in a month's time, as I think in my case my gut microbiome is badly messed up due to way too much antibiotics in my childhood and young adult life. Will post about the results.
my doctor also told me that there is no standard for healthy intestinal flora.Two healthy people may have very different intestinal flora.

 

A Chinese man undergoing desenz from 2021.8 to 2022.2, it became worse from 1.5 to 4.5 days, do not know it is spontaneous deterioration or by desenz. Believe POIS is a kind of immune diseases. My case:https://poiscenter.com/forums/index.php?topic=4104.0

Clues

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Re: Clues' case so far
« Reply #35 on: February 18, 2022, 02:49:57 PM »
hope fecal transplant will help you. God bless you

Thank you so much Lihua.

Clues

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Re: Clues' case so far
« Reply #36 on: March 26, 2022, 04:21:34 AM »
Update: I got my fecal transplant via colonoscopy yesterday, at this clinic outside Oslo, Norway. The clinic claims to be fairly cutting-edge in terms of its clinical approach to fecal transplants.

This was the process:
  • I fasted the whole day before the treatment.
  • To empty the digestive system prior to the procedure, I took Endofalk according to a specific schedule the day before the colonoscopy. It's used because its laxative effect doesn't persist after the colonoscopy.
  • Two hours prior to the procedure, I took 4 2-mg tablets of Imodium, which is usually sold as an anti-diarrhea drug.
  • Prior to the colonoscopy, they gave me intravenously a pain reliever, but also more importantly a drug that calms down and virtually immobilises the gut for a while. Can't recall the name of the drug.
  • The colonoscopy itself was virtually painless and pretty quick. I could see the video stream from the colonoscopy camera in high resolution on two big screens. They soaked up any remaining liquid and fecal matter in the gut, before inserting the fecal matter via a tube
  • I could see them insert the fecal matter into the tube via syringes. And wow, it was a lot! I'd say a quite full gut's worth of poop.
  • During the colonoscopy and for the subsequent hour, they monitored me carefully and gave me some more Imodium and the drug whose name I can't recall to make sure it stayed in.
  • I lay on a hospital bed on my right side for an hour after the treatment, followed by carefully walking around the clinic for a good while, to make sure I didn't have a bowel movement. Apparently the first couple of hours after they insert it are the most critical.
  • All was well, and I went home. As instructed, I ate very very small meals at a 3-hour interval. They said I shouldn't continue fasting, because the new microbiota need nourishment.
  • Now I've got to try and retain the fecal matter as long as possible, to let the new bacteria set up shop.
  • Over the next two months, I've been instructed to stay away from processed food and food that would normally irritate my gut, such as gluten. This surprised me a little bit. Only after some time has passed should I try to introduce those foods.

Overall I'm super happy with the procedure, and confident that they are doing a good job applying the incomplete science of gut health in a clinical setting. They monitor the result of every treatment, and have a pretty high rate of symptom reduction or elimination. But it should be mentioned they only accept patients when they believe a fecal transplant can be successful. By far the biggest indication for that, according to them, is if the symptoms started after an antibiotics treatment. This is based on their own clinical research.

Ultimately it's a crap shoot (pun intended) as to whether it will relieve my IBS. And whether it'll help my POIS is yet another big question mark. They say it usually takes 2-3 weeks for IBS symptoms to clear up (if they do), and 2-3 months for cognitive and fatigue symptoms to go lessen or go away (again, if the treatment turns out to help).

Why they go for colonoscopy instead of gastroscopy is a bit of a long story. But they do offer the latter as well, it's just not the first thing they try for various reasons. If my treatment doesn't work, I'm tempted to go back and try fecal matter from a different donor, potentially with a different procedure. But let's see how I do first. In total the whole thing ended up costing about 26000 NOK including consultation and drugs.

NB! Do not try this at home! There is a billion reasons why it should be left to professionals IMO. Also, please note that I'm not advocating for FMT as a general POIS cure. It makes sense to try in my particular case because of IBS and a clear connection between gut symptoms and other POIS symptoms.

Please post any questions in this thread. I don't read the forum regularly, so I'm likely to miss anything except DMs and posts in this thread.

Hopeoneday

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Re: Clues' case so far
« Reply #37 on: March 26, 2022, 05:06:14 AM »
Thanks for this Clues, lets see how its goes...
Some peoples complitly cured theirs CFS_ME with this procedures.
Dr-pois.

Quantum

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Re: Clues' case so far
« Reply #38 on: March 26, 2022, 11:10:32 AM »
Keep us updated with the results, Clues !
I wish you the best possible outcome :)
You are 100% responsible for what you do with anything I post on this forum and of any consequence it could have for you.  Forum rule: ""Do not use POISCenter as a substitute for, or to give, medical advice" Read the remaining part at http://poiscenter.com/forums/index.php?topic=1.msg10259#msg10259

Clues

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Re: Clues' case so far
« Reply #39 on: March 27, 2022, 03:44:58 AM »
Thanks a lot Quantum. Will post results in this thread for sure!