POIS treatment: theory & supplement stack

[itsmel]

Hi,

Just want to report back on my status.
So far everything is normal and still able to O.
The current supplements I take are,

1. B12 Lozenge with L-5 MTHF.
2. Electrolyte powder containing magnesium and potassium.
3. Soylent, which has all the vitamins at 20% daily value.

I'm pretty much done here but if you have any questions, you can shoot me a PM.
Great job nana1,

See ya.

[b_jim]

2. Electrolyte powder containing magnesium and potassium.

I'm interrested by this point. It's like if I have an electrolyte deficiency after ejaculation. Can you give the name of this powder ?

[itsmel]

2. Electrolyte powder containing magnesium and potassium.

I'm interrested by this point. It's like if I have an electrolyte deficiency after ejaculation. Can you give the name of this powder ?

Sure b_jim

https://www.amazon.com/Emergen-C-Electrolyte-Replacement-Potassium-Magnesium/dp/B002HWRY5S?keywords=EMERGEN-C%2BELECTRO%2BMIX&qid=1540684122&sr=8-5&ref=sr_1_5&th=1

[b_jim]

Oh thanks !
I find it's a very nice point of view, few discussed in our forum.
I suspect a lack of electrolytes for several reasons :

- After ejaculation, I become very sensible to carbs especiialy sugar with diahreas. And I don't have the explanation : it could be a lack of electrolytes used for carbohydrates absorbtion.

- Semen is rich in electrolytes : lot of potassium and some magnesium.

- Ou of Pois, in summer when I work hard, I can"t sleep and I feel depressed for 1 day. I lost water and probably electrolytes.

- Chlorid element seems to play a role in my fasciculation symptom in/out of Pois so I put salt in my water or meals...

[b_jim]

Ingredients : vitamines C, E and group B
Zinc, manganese
Electrolytes : Mg, Ca, K, Ph, Na
Probiotics, melatonin, caffeine MSM (?)

[Hopeoneday]

Hi Itsmel.

You sayed before about face after O:

On the physical aspect after an O,
1. My face looks like I aged several years.
2. My face would feel saggy or loose but after taking Excerdrin, my face feels nice and firm but I don't know which ingredients from Excerdrin caused this.

I hawe the same isues on face , look older several years an slugish face...
Excerdin hawe -cofein, paracetamol, aspirin(this is combination for migrains).
After O in pois i hawe migrains to, so my body is in migrains mode and flu like mode
too.

About your stuck for pois -
1. B12 Lozenge with L-5 MTHF.
2. Electrolyte powder containing magnesium and potassium.
3. Soylent, which has all the vitamins at 20% daily value.

What are you think is main solution from those 3 for your pois?
B12 Lozenge with L-5 MTHF because mutation?
All 3 togedher in sinergy slowe mutation isue?

[itsmel]

Oh thanks !
I find it's a very nice point of view, few discussed in our forum.
I suspect a lack of electrolytes for several reasons :

- After ejaculation, I become very sensible to carbs especiialy sugar with diahreas. And I don't have the explanation : it could be a lack of electrolytes used for carbohydrates absorbtion.

- Semen is rich in electrolytes : lot of potassium and some magnesium.

- Ou of Pois, in summer when I work hard, I can"t sleep and I feel depressed for 1 day. I lost water and probably electrolytes.

- Chlorid element seems to play a role in my fasciculation symptom in/out of Pois so I put salt in my water or meals...

No problem, b_jim, doesn't hurt to try. Good luck!

[itsmel]

Hi Itsmel.

You sayed before about face after O:

On the physical aspect after an O,
1. My face looks like I aged several years.
2. My face would feel saggy or loose but after taking Excerdrin, my face feels nice and firm but I don't know which ingredients from Excerdrin caused this.

I hawe the same isues on face , look older several years an slugish face...
Excerdin hawe -cofein, paracetamol, aspirin(this is combination for migrains).
After O in pois i hawe migrains to, so my body is in migrains mode and flu like mode
too.

About your stuck for pois -
1. B12 Lozenge with L-5 MTHF.
2. Electrolyte powder containing magnesium and potassium.
3. Soylent, which has all the vitamins at 20% daily value.

What are you think is main solution from those 3 for your pois?
B12 Lozenge with L-5 MTHF because mutation?
All 3 togedher in sinergy slowe mutation isue?

Hi Hopeoneday, the main ingredient for me here is B12 Lozenge with L-5 MTHF.
When I look up paracetamol, apparently it increases aldosterone and decreases cortisol.

https://www.ncbi.nlm.nih.gov/pubmed/27217499

But I don't have enough knowledge to interpret them but it could be a lead.
Maybe I have low aldosterone or high cortiosol?

Good luck!

[CuriousCharacter]

I've been taking nanna1's stack for about two months now. I've made some small modifications over the past few weeks, and have been completely symptom-free for the past week.

It's hard to tell whether this trend will continue, but I've certainly never experienced such a strong placebo effect throughout the past couple years of debugging POIS.

I posted more details about this here: https://poiscenter.com/forums/index.php?topic=2831.0

Nanna1 - thank you so much for what you do! I feel like I'm finally seeing the light at the end of the tunnel.

[BoneBroth]

I'm a new POISer in this forum and I'm on Nanna1's POIS stack since two weeks ago but I have not noticed any much improvement yet (maybe it takes much longer time?). I had the first NE tonight since I started, but unfortunatly it happened at the same day as a got a cold break out (actuallt the cold caused the NE due to bad sleep) so I'm not sure what causes the headache now.. ;/.. But I feel that familiar tense feeling in the forehead that use to come with POIS. I had POIS since I was teenage. Over 40 now and its a life challange... Tryed to do the survey today but was stopped by the headache. I believe I have much experience to contribute.

I wonder why there is a strikeout on the folloing ingredients on Nanna1's original post. Have they been removed from the stack?
---Benfotiamine, vitamin B1 (150mg) [h1H downregulator]
---eicosapentaenoic acid, EPA (900mg) [AA synthesis inhibitor, AA blocker]
---docosahexaenoic acid, DHA (150mg) [AA synthesis inhibitor]

Should the stack also be taken right after a NE? What is the best thing to do after a NE anyway?

I have also aired an idea about blood vessel elasticity as a contributing factor to POIS and I would be happy to hear Nanna1's and all of your others thoughts about that. Here is the thread: https://poiscenter.com/forums/index.php?topic=2832.0

[Vandemolen]

I want to report that Nanna’s stack didn’t work for me. But I only use it for 10 days. Nanna said that you have to use it for 3 or 4 weeks. So I will try about 2 or 3 weeks again. I was also already a bit sick because of my allergy of Cefuroxim. I finished the cure on Thursday. So why did I try yesterday? That’s because Wednesday I have an appointment with my POIS doctor. I thought if it worked I could try it Monday again to be sure it works for me. And then I could tell my POIS doctor. When it’s sure that it worked for me he would take it more serious.

I will report when I tried it again. Now my fingers, feet and skull are very dry. My troath, mouth, tongue and nose are dry. Niacin didn’t work for me but at least it helped a bit against a dry mouth and nose. There is also another thing. I also over masturbated. For more than 4 hours. Maybe it doesn’t work that long? Doing it for this period is also unhealthy for a man without POIS.

I will give it another try. Because when I tried the first time I had candida. I still have candida, almost 2 months now. I hope to get rid of candida in a week because my doctor gave me an anti fungus medicine. Maybe it will work when I don’t have candida.

I will also try taurine when out of Candida.

[Iwillbeatthis]

Methyl folate 400ug seems to give me brain fog for a few hours every time i try this stack. I have very low folate so why is this the case, is it due to overmethylation? I don't seem to have the characteristics of over methylation so its strange to me. I've heard normal folic acid is bad so what do I do now?

[Iwillbeatthis]

Ps I tried looking for 200ug metafolin and couldn't find anywhere

[itsmel]

Just an update,

The effects of the B12+B9 are beginning to subside but the effects are still overall positive so it still my supplement to go but I take it once a week because if I take it on the daily basis my cortisol shot up near the higher range. That's when I stopped and then took it once it week before my cortisol normalize. This supplement has this bell curve effect to it as one of the member linked and to my experience it is definitely true.

I would like to join the discussion about the Cox-2 inhibitor. As I stated initially from the start I took Tylenol for premature ejaculation and it works really well but it also greatly alieves some of the nuero issues such as anxiety, depression and increase verbal fluency. I felt that I was a whole new person. I started to look into why only Tylenol would help but not Ibuprofen and Asprin and based on the chart that nana1 posted, Tylenol has higher rating for COX-2 inhibitor than the others and can confirm that because I tried Ibuprofen and Asprin and they dont give me the same results as Tylenol.

For people who have PE, I urge you to try Tylenol or Acetaminophen and they are OTC.
Currently I'm trying to get my hands on the generic version of Celebrex.

Although I'm curious about the statement made by nana1 regarding the vitamin D that its even much stronger than Tylenol or paracetamol which means it should help my conditions but the last time I tried it, I felt it gave me more inflammation but I found that you must supplement with other vitamins such as K2 and Magnesium so I'll report back on that.

brb

[Nas]

Just an update,

The effects of the B12+B9 are beginning to subside but the effects are still overall positive so it still my supplement to go but I take it once a week because if I take it on the daily basis my cortisol shot up near the higher range. That's when I stopped and then took it once it week before my cortisol normalize. This supplement has this bell curve effect to it as one of the member linked and to my experience it is definitely true.

I would like to join the discussion about the Cox-2 inhibitor. As I stated initially from the start I took Tylenol for premature ejaculation and it works really well but it also greatly alieves some of the nuero issues such as anxiety, depression and increase verbal fluency. I felt that I was a whole new person. I started to look into why only Tylenol would help but not Ibuprofen and Asprin and based on the chart that nana1 posted, Tylenol has higher rating for COX-2 inhibitor than the others and can confirm that because I tried Ibuprofen and Asprin and they dont give me the same results as Tylenol.

For people who have PE, I urge you to try Tylenol or Acetaminophen and they are OTC.
Currently I'm trying to get my hands on the generic version of Celebrex.

Although I'm curious about the statement made by nana1 regarding the vitamin D that its even much stronger than Tylenol or paracetamol which means it should help my conditions but the last time I tried it, I felt it gave me more inflammation but I found that you must supplement with other vitamins such as K2 and Magnesium so I'll report back on that.

brb

I've tried Celebrex I think for five days and I didn't notice any change. I haven't tried Paracetamol extensively because I usually look down upon it. Was paracetamol instant for you? Or did it take more time to be effective?

[itsmel]

Hey Nas,
Paracetamol works within 2 hours but the current issue for me is that it has become less effective over time. I suspect that I have high levels of prostaglandin due to vitamin d deficiency but I can't tolerate vitamin d and it could be that I also have VDR (vitamin d receptor) issue from the genetic testing. Not sure if there any relations and dont have knowledge on them so I can't comment. They are,

VDR TAQ +/-
VDR BMS +/-

Sorry it didn't work out for you. Have you also try vitamin d?

[Nas]

Hey Nas,
Paracetamol works within 2 hours but the current issue for me is that it has become less effective over time. I suspect that I have high levels of prostaglandin due to vitamin d deficiency but I can't tolerate vitamin d and it could be that I also have VDR (vitamin d receptor) issue from the genetic testing. Not sure if there any relations and dont have knowledge on them so I can't comment. They are,

VDR TAQ +/-
VDR BMS +/-

Sorry it didn't work out for you. Have you also try vitamin d?

Hey Itsme
Yeah I did but I also tried it with other stuff so I'm not sure if it works at all. Vitamin D is a mast cell stablizer so I might visit it again, plus it can be found anywhere so its less of a pain to buy.
In fact, I might do a test to see if I'm deficient. I very much doubt it since I live in the hottest spot on earth so there aren't really any lack of vitamin d in my environment.

[Vandemolen]

Hey Nas,
Paracetamol works within 2 hours but the current issue for me is that it has become less effective over time. I suspect that I have high levels of prostaglandin due to vitamin d deficiency but I can't tolerate vitamin d and it could be that I also have VDR (vitamin d receptor) issue from the genetic testing. Not sure if there any relations and dont have knowledge on them so I can't comment. They are,

VDR TAQ +/-
VDR BMS +/-

Sorry it didn't work out for you. Have you also try vitamin d?

Hey Itsme
Yeah I did but I also tried it with other stuff so I'm not sure if it works at all. Vitamin D is a mast cell stablizer so I might visit it again, plus it can be found anywhere so its less of a pain to buy.
In fact, I might do a test to see if I'm deficient. I very much doubt it since I live in the hottest spot on earth so there aren't really any lack of vitamin d in my environment.

Before going on a holiday to Dubai I googled a bit and came out at this article that says that 90% of the Dubai population has a vitamin D defiency. I know that in Dubai they spend a lot of time inside in malls and airconditioned areas. My point is that it depends on your lifestyle. If you live in The Netherlands like me and you go outside a lot your vitamin D will be ok. And if you live in Dubai and you spend the most of your time indoors then your vitamin D will not be ok.

I had a vitamin D level of 16 and I go a few times in a year on holidays to the sun. Only 50.000IE a week helped to raise my level. Now it is 160.

https://gulfnews.com/going-out/society/90-of-uae-population-vitamin-d-deficient-says-dha-official-1.2113556

[Nas]

Hey Nas,
Paracetamol works within 2 hours but the current issue for me is that it has become less effective over time. I suspect that I have high levels of prostaglandin due to vitamin d deficiency but I can't tolerate vitamin d and it could be that I also have VDR (vitamin d receptor) issue from the genetic testing. Not sure if there any relations and dont have knowledge on them so I can't comment. They are,

VDR TAQ +/-
VDR BMS +/-

Sorry it didn't work out for you. Have you also try vitamin d?

Hey Itsme
Yeah I did but I also tried it with other stuff so I'm not sure if it works at all. Vitamin D is a mast cell stablizer so I might visit it again, plus it can be found anywhere so its less of a pain to buy.
In fact, I might do a test to see if I'm deficient. I very much doubt it since I live in the hottest spot on earth so there aren't really any lack of vitamin d in my environment.

Before going on a holiday to Dubai I googled a bit and came out at this article that says that 90% of the Dubai population has a vitamin D defiency. I know that in Dubai they spend a lot of time inside in malls and airconditioned areas. My point is that it depends on your lifestyle. If you live in The Netherlands like me and you go outside a lot your vitamin D will be ok. And if you live in Dubai and you spend the most of your time indoors then your vitamin D will not be ok.

I had a vitamin D level of 16 and I go a few times in a year on holidays to the sun. Only 50.000IE a week helped to raise my level. Now it is 160.

https://gulfnews.com/going-out/society/90-of-uae-population-vitamin-d-deficient-says-dha-official-1.2113556

Perhaps but I used to go alot outside before POIS. In fact I developed my tan skin color because of the amount I spent outside. I was very extroverted before POIS.

[demografx]

...going on a holiday to Dubai...

Have a nice, POIS-free visit!