Hi Harrie, and welcome to poiscenter 
Thanks for taking the time to share your positive experience with forskolin and zinc.
There are some preliminary scientific data showing that forskolin may increase testosterone level ( see https://www.greatgreenwall.org/supplements/forskolin-increase-testosterone/ ) . Zinc is well known to be positive for the prostate.
This method of control of POIS symptoms could be in the same family as TRT ( Testosterone Replacement Therapy), but with probably fewer potential side effects, if forskolin does not have too many side effects, and does not have the cardiovascular side effects of testosterone itself, as well as its effect on fertility. Since forskolin is not very well known up to now, it is hard to say.
If your method is still consistently effective 3 months from now, let me know - I would be happy to add it to my "POIS Types chart and their possible control methods", found at the beginning of this thread
What were your other symptoms, apart from brain fog? How long did your POIS attacks usually last, with no inc and forskolin?
And, about your control method, do you take Forskolin and zinc every day, or only after orgasm? Did you ever tried taking it 20 to 60 minutes before orgasm, to see if it would be more effective still?
Thanks for your reply. Although I have had these symptoms for over two decades, I never thought to connect them to having orgasms. As a result I am almost embarrased to say that I had them regularly (almost daily) during this period and I can't remember having periods of not having orgasms for longer than three, maybe four days.. This might explain why I experienced my symptoms lighter than some of the members here, but also in a more continuous, constant state. Its only after I withheld myself from having orgasms a couple of months ago, that I experienced the severe negative benefits right after having one again.
My most frequent symptoms are brainfog combined with headaches, memory problems and concentration issues (difficult to focus). In addition I also feel very tired afterwards (I notice this now, although I also tend to sleep too little) and I have a chronic nose cold (not sure if this is related). I have been seeing doctors about this since 2004 and I've done MRI's, memory tests, have been treated for conditions like a slow Thyroid, a B12 defficiency, etc, and tried a boat load of supplements, but non of it helped.
Since I started to link my symptoms to orgasms, I did try to limit them as much as possible which comes down to basically once a week. I now experience the symptoms for approx 3 days afterwards, of which the first day is by far the most severe. One thing that I additionally notice now is that I become easily overstimulated (I always had this too some degree, I can't wear regular jeans for instance) and get extremely short tempered and angry when this happens (which isn't usefull in a household with three small kids).
I found this forum several months ago and tried some of the proposed solutions in this topic, e.g vitamin D / vitamin B3 / Macca Tea that didn't help. I also read in one of the topics about anti-allergy pills and because I already used Centrizine, I started to take 2 10mg pills 10 minutes before an orgasm. This brought some relief for the physical symptoms, but did not help with being over stimulated and hot tempered. Now that I have tried the Forskolin + Zinc combination, I feel much more relaxed and (as far as I can tell) completely symptom free.
I use Forskolin + Zin only right after or approx. an hour after having an orgasm (I prefer to take it when I go to bed, because I might get a bit nauseous). I haven't tried taking it before (I will try that next time), so I can't judge on that. I also didn't do follow up dosseses, although I have to admit that I had a 5 day period with daily orgasms, so I took it 5 days in a row. I could try to use it daily, but I now had my last orgasm two days ago, so I took it then and now still feel fine. In the beginning I combined Forskolin + Zinc with the centrizine, but soon started to take only the Forskolin + Zinc with similar results.
I am definitly not a health expert, so I don't know why it works as it does, but I did feel so positive about it that I wanted to share. I hope this helps to provide some additional explanation and hopefully some others (for instance who are still searching for a solution) decide to try it and experience positive effects as well.
