Update #3: I've declared sufficient success with eggs (choline source) to move on with the next steps as of a week or so ago. General observations:
1) Choline appears to clear speech and muscle/tongue and lip swelling-like issues around the mouth as well as irritability as a function of pois.
2) I have several of the genes that limit choline and folate absorption. these seem likely to play a roll in my pois. (23&me + promethease)
3) I tried adding beets (betaine, which is a derivative of choline) into the diet. Without choline, beets addressed the brain fog side of things, but not the items that choline addressed.
4) when I had too much choline supplement in one day, I appeared to see nose drainage and some of the symptoms that other pois suffers see. They may have the opposite issue, which is too much rather than too little choline. Benedryl seems to help some people though I haven't tried- I would bet that the anticholergenic effects of Benedryl could address those with that type of issue. Just a guess though with very little proof.
5) I've started taking 1/day simple B Complex vitamins (with methylfolate - Thorne brand) and adding in 1/day choline (also Thorne). I add a second choline the evening after O as I take the others in the morning. For the last week, I have had clear (read almost no noticeable) symptoms. I will report back in a few weeks to indicate if this is still the case (since one week is not sufficient time to judge and some people have crushing fatigue after 1 week on B vitamins). See this chain for more info (
http://poiscenter.com/forums/index.php?topic=1059.msg9571#msg9571)
thanks,
TT