Yeah, we need to resarch this more.
VDR receptor is inwolved in ewry cell in human body.
You hawe all details in link and its seams what helped
poisers alsou help to incriese repair vdr receptors.
What doesnt fit in my case is that i hawe a wery strong bones.
So maybe this isnt important for pois angle if this theory is
connected.
Benefits and roles ov vit D and receptors:
The most popular benefits for vitamin D3 is it’s role in bone health.
Low blood levels of vitamin D3 are associated with lower bone density (R). Clinical trials have shown that Calcitriol is helpful for people with lower bone density (R).
VDR activation induces the expression of liver and intestinal phase I detox enzymes (e.g., CYP2C9 and 3A4) that play major roles in metabolizing drugs and toxins (R).
The Vitamin D Receptor is important for hair growth and loss of VDR is associated with hair loss in experimental animals (R).
The VDR regulates intestinal transport of calcium, Iron and other minerals (R).
Since many infections block the Vitamin D Receptor, our body can’t fight them off well. Researches are using a combination of Calcitriol (active D) and antibiotics with good effects in many conditions. It’s a good idea to gradually eliminate pathogens over several years to minimize immune reactions. (R)
Calcitriol/VDR increases dopamine by increasing the enzyme that’s the rate limiting step for dopamine production (tyrosine hydroxylase) (R).
Calcitriol/VDR increases tyrosine hydroxylase in the hypothalamus (R), adrenal glands (R), substantia nigra (R) and likely other areas. This means that it increases productions of dopamine, adrenaline and noradrenaline. Although having more neurotransmitters is a good thing, Tyrosine hydroxylase also increases oxidative stress, so it doesn’t provide a free lunch. (R)
Calcitriol increases GAD67 and therefore increases GABA (R).
Calcitriol increases glial derived neurotrophic factor (GDNF) (in vitro), which protects dopamine neurons. (R)
Researchers hypothesize that inadequate levels of circulating vitamin D could lead to dysfunction in the substantia nigra, an area of the brain in which the characteristic dopaminergic degeneration occurs in parkinsonian disorders (R).
A high prevalence of vitamin D deficiency has been reported in Parkinson’s patients and Parkinson’s has been associated with decreased bone mineral density (R).
Active D has different effects in cancer. In breast cancer cells, estrogen (and aromatase) production decreased, while Testosterone/androgens increased (both GOOD). In adrenal cancer cells, it decreased DHT (GOOD). In prostate cancer cells, the production of testosterone and DHT increased (BAD). (R)
High levels of the enzyme that breaks down active D is found in lung cancer (R) and breast cancer (R). This would suggest that increasing its levels are good for breast and lung cancer.
Active vitamin D increases prolactin production (R).
Technical: 1,25D induces RANKL, SPP1 (osteopontin), and BGP (osteocalcin) to govern bone mineral remodeling; TRPV6, CaBP(9k), and claudin 2 to promote intestinal calcium absorption; and TRPV5, klotho, and Npt2c to regulate kidney calcium and phosphate reabsorption (R).
Poll