Great success using antihistamine Lergigan, FODMAP free oral solution

[freddie]

Well I tried it mate and guess what. Back to square one. Now another 2 weeks for me to find myself again.

very sorry to hear that. for your two weeks, but mostly because you will need to be searching more for the right solution for you.

I have my promethazine hydrocloride (Lergigan) batch on its way. but I will continue avoiding O's for now. So it may take a while before I report my results.

[Cosmic1982@]

Let me know how you get on mate.
I'm trying vitamin d with K2 atm where I've seen a slight change but it has affected my sleep so I can't weigh up whether it's the lack of sleep taking the edge of or the happy vitamin 🤔

Hope it works for you mate 👍🏻

[Huser]

Meshal, regular person dont have overactivation of dopamine during orgasm, they have normal activation of dopamine receptors, resulting in normal levels of glutamate after orgasm that will not cause problems in the brain.

Those who have overactivation of dopamine receptors will produce to much glutamate and too much glutamate harms brain.

You can try that and drink too much alcohol. Next day brain will produce too much glutamate and regular person will feal sick.

[Cosmic1982@]

Meshal, regular person dont have overactivation of dopamine during orgasm, they have normal activation of dopamine receptors, resulting in normal levels of glutamate after orgasm that will not cause problems in the brain.

Those who have overactivation of dopamine receptors will produce to much glutamate and too much glutamate harms brain.

You can try that and drink too much alcohol. Next day brain will produce too much glutamate and regular person will feal sick.

Hello huser

Thanks for the info. Very Interesting.
When you say try that, what are you suggesting we try? Sorry if I misunderstood

[Sisyphus]

@ mike_sweden
Congrats on finding something that works for your pois.
I wondered if you can confirm your current dosage? Are you still taking this at 2100 every night as well as 1 hour before orgasm or are you only taking it 1 hour before orgasm?

[mike_sweden]

@ mike_sweden
Congrats on finding something that works for your pois.
I wondered if you can confirm your current dosage? Are you still taking this at 2100 every night as well as 1 hour before orgasm or are you only taking it 1 hour before orgasm?

only take it about 1-3h before orgasm depending on how long time it takes me to get my girlfriend on her back :-)

[Sisyphus]

Hehe . Nice one. Thanks!

[mike_sweden]

Lergigan is still working very good even though we are somewhat into autumn and weather is getting colder. 

[mike_sweden]

Can now confirm that Lergigan works well year around, having had some days with -6 degrees.

Having sex several times per week with my girlfriend. No issues at all. Medicine needs to be combined with strict FODMAP for me.

[Meshal]

4.5 months and promethazine is still working as intended.

However, even though I use it 1-2 times a week, I started to feel slight pinching pain in both of my kidneys, when I lay on bed specifically.

I asked the pharmecist if it can cause any kidney issues, he replied that promethazine isn't intended for long term use.

Before I tried this medicine my Urologist already gave me the ok to use it long term, so I'll have to discuss with him to understand the causes of this dull pain a bit more.

[Meshal]

5 months update. It is still working.

I still can't believe how a simple affordable drug is transforming my life completely, I am ever so grateful.

Few thoughts I have:

- Excessive use, like some other pois treatments, will cause it to lose effect overtime. At one point I decided to use one everyday before O, in the third day I noticed it wasn't as effective as usual, and the pois symptoms were still present after O. But such issue is easily avoidable if you manage your schedule just right.

- I realized more than 7mL dosage wasn't necessary, settled for 5 mL and it's just as effective as 7.5+mL, didn't notice any difference in symptoms suppressions.

- I now want to improve upon it but I still lack the pharmaceutical experience to achieve what I need.

So while it does work on suppressing my symptoms, like Quantum said, it is hazardous to take it during the day due to the drowsiness.
I still find it difficult to take even during night time, what is supposed to help me sleep due to the drowsiness actually raise my anxiety levels very high, I find it really hard to sleep or even stay put, I have to literally get up physically and move my body every 10 minutes just to relieve the anxiety and stress I get from the dose, even if it's something as small as 0.5mL. Worst part is this starts an hour after taking the dose and ejaculate and lasts for about 6 hours. Some days where I have regular headaches I simply avoid using the drug and orgasm naturally just so I can get a good night sleep, even if it costs me the POIS symptoms.

So this is tailored more towards the forum member Quantum, I randomly came across an old comment of yours and you mentioned you were a pharmacist, I was pleasantly surprised, no wonder why you play such a big role in the forum.

Is it possible to find a work around for this? To get the best results out of antihistamine with at least minimizing the side effects I'm facing every time?
Could caffeine be a major factor even though I take my dose 12 hours at least after my last cup of coffee?

a reminder I'm using Rhinathiol Promethazine syrup.

[Quantum]

5 months update. It is still working.

I still can't believe how a simple affordable drug is transforming my life completely, I am ever so grateful.

Few thoughts I have:

- Excessive use, like some other pois treatments, will cause it to lose effect overtime. At one point I decided to use one everyday before O, in the third day I noticed it wasn't as effective as usual, and the pois symptoms were still present after O. But such issue is easily avoidable if you manage your schedule just right.

- I realized more than 7mL dosage wasn't necessary, settled for 5 mL and it's just as effective as 7.5+mL, didn't notice any difference in symptoms suppressions.

- I now want to improve upon it but I still lack the pharmaceutical experience to achieve what I need.

So while it does work on suppressing my symptoms, like Quantum said, it is hazardous to take it during the day due to the drowsiness.
I still find it difficult to take even during night time, what is supposed to help me sleep due to the drowsiness actually raise my anxiety levels very high, I find it really hard to sleep or even stay put, I have to literally get up physically and move my body every 10 minutes just to relieve the anxiety and stress I get from the dose, even if it's something as small as 0.5mL. Worst part is this starts an hour after taking the dose and ejaculate and lasts for about 6 hours. Some days where I have regular headaches I simply avoid using the drug and orgasm naturally just so I can get a good night sleep, even if it costs me the POIS symptoms.

So this is tailored more towards the forum member Quantum, I randomly came across an old comment of yours and you mentioned you were a pharmacist, I was pleasantly surprised, no wonder why you play such a big role in the forum.

Is it possible to find a work around for this? To get the best results out of antihistamine with at least minimizing the side effects I'm facing every time?
Could caffeine be a major factor even though I take my dose 12 hours at least after my last cup of coffee?

a reminder I'm using Rhinathiol Promethazine syrup.

Hi Meshal,
Thanks for your good words about me   I am glad that my implication here have been useful to you.
About the side effects you have, it is always the same way to evaluate this, with prescription drugs:  the advantages must be greater than the side effects.  So, if the drowsiness and restlessness are easier on you than your POIS symptoms, and that those side effects are shorter, and have less impact on your life, than it worth it. When taking a drug, it is to, overall, improve our situation, obviously.  So you have to ponder on the pros and cons !