Free Flow Discussion about POIS

[demografx]

Just a periodic reminder to
please bookmark this site:
https://groups.google.com/forum/m/?hl=en#!forum/poiscenter

If you ever experience any unforeseen technical difficulties here!

It is our alternate/emergency POISCenter site at Google Groups.

[Observer]

Hi Observer,[edit-demo] for those who don't know, check Oberver''s starring role in CBS' Austrailia documentary on POIS! See Welcome Page~~[end edit]

Personally, I use rosemary essential oil ( brand Aromaforce, form A.Vogel), 2 to 3 drops in a glass of water, stirring well before drinking.  But rosemary essential oil have a camphor-like taste, so it may be not acceptable to everybody.  But I get good results with it and the taste is ok for me.  If it was not, I would use rosemary extract in capsuled powder (  like this: http://www.vitacost.com/solaray-rosemary-leaf-extract-275-mg-45-vegetarian-capsules ), but I find the essential oil more efficient, the brand I use is made from the whole plant, so there may be more in it than just rosmarinic acid ( the IDO inhibitor) that is helpful for me.

Thanks very much, Quantum. I would definitely give it a try. I will probably start trying the powder brand to see if I notice some improvement in case I happen to be in POIS.

Best Regards.

[demografx]

Welcome back, Observer!

Thanks demografx!

It's very interesting what you said Quantum. You know, I was so overwhelmed by cognitive symptoms before, that I didn't have time to think about the other emotional issues that flare up with POIS. I should definitely try this Rosemary extract to see if it works, as I have somehow limited my niacin dosage.

I would share the results with you. Are you using a particular brand?

I'm not attempting anything else, Observer, my TRT regimen is STILL a week to week struggle to find the right combination. After all these years, I'm still working on it!!!

[demografx]

Questionable article IMO about a doctor treating a woman with "POIS". His "undisclosed treatment" claims to treat her POIS, but must be applied every time she has sex.
http://www.nation.co.ke/lifestyle/saturday/Elusive-ecstasy/1216-3424912-13lnqvd/

[Quantum]

Questionable article IMO about a doctor treating a woman with "POIS". His "undisclosed treatment" claims to treat her POIS, but must be applied every time she has sex.
http://www.nation.co.ke/lifestyle/saturday/Elusive-ecstasy/1216-3424912-13lnqvd/

Thanks for the link, Demo.

This Dr Osur seems to be a specialist ( sexologist) in Kenya.  He sure knows a lot more than the average physician about POIS, which in itself is interesting.

I have managed to find an e-mail for him, and wrote him about his POIS article, asking him what treatment he has prescribed, and inviting him to take a look at our poiscenter forum.  I will let you know about any answer I receive. 

He is clear about the fact that what he has prescribed is only bringing relief, and is not a cure, and have to be taken each time.  But I would like to know what he have prescribed, anyway.

[MirkoThiel0]

nice think Quantum,
i hope we get an interesting answer.

[Observer]

Welcome back, Observer!

Thanks demografx!

It's very interesting what you said Quantum. You know, I was so overwhelmed by cognitive symptoms before, that I didn't have time to think about the other emotional issues that flare up with POIS. I should definitely try this Rosemary extract to see if it works, as I have somehow limited my niacin dosage.

I would share the results with you. Are you using a particular brand?

I'm not attempting anything else, Observer, my TRT regimen is STILL a week to week struggle to find the right combination. After all these years, I'm still working on it!!!

Hello again demografx. I was interested in that particular Rosemary brand that Quantum is using.

I had the opportunity to meet another POIS member this weekend, and we talked also about your TRT treatment. I find these encounters to be highly rewarding, and so far I have met four POISers during this time! It's always interesting to see how other people can relate to your life memories and completely understand you.

SoldatRas (he's a new forum member, I'm using his nickname... he lives in the same city where I am living right now, amazing coincidence) told me that he was just starting his experience with niacin, and that he had experienced a 50% relief. He will be doing more trial tests with a slighlty higher dose during the coming days, to see if he makes some improvement.

We talked about some issues related to cortisol (the stress-triggered hormone), and he thinks (also I do) that is one of the keys to control and reduce the symptoms. It's definitely worth considering, if we take into account the relationship between POIS <-> Anxiety/stress (POIS can induce anxiety/anxiety can worsen POIS).

After reading the following link about this hormone, I found out that many advices are not uncommon to us and have been talked here before. You can find it here: http://teeccino.com/building_optimal_health/148/Six-Tips-To-Reduce-The-Stress-Hormone,-Cortisol.html

I also believe this part, which I found in another website, is really interesting, since I can say that I have experienced it before:

Internist Kogan, on the other hand, believes the physical damages of increased technology use could be severe. She says that prolonged use can overstimulate the nervous system and increase production of cortisol, the so-called stress hormone.

“It’s the fight-or-flight response,” explains Kogan. “When you’re using these technologies, your cortisol will be pumping through the roof. And you don’t want higher levels of cortisol,” which increases your risk of experiencing anxiety, depression, insomnia, high blood pressure and diabetes.

She advises that you reduce your technology use if possible, but warns against putting your job in jeopardy. If you need to remain plugged in, she suggests making a special effort to take time out of the day to relax by taking yoga, practicing meditation or drinking valerian tea at night.

Because technology assails the nervous system, more sleep will help it heal, says Kogan. Ironically, nighttime technology use is also linked to sleep issues, so she recommends you turn off all media at least two hours before bed.<i/>

http://www.forbes.com/2010/06/29/technology-computers-health-stress-forbes-woman-well-being-screen-time.html

Some food for thought, definitely.

BR everyone,

[Quantum]

Hi everyone.  I have received an answer from Dr Osur to the e-mail I have sent to him just yesterday.  Here is his answer:

Dear Quantum,
Thank you for your mail. I am among the few doctors in Africa that have taken an interest in sexual health so that is why I am familiar with POIS.
Because the etiology of POIS is not clear, what we do now is to treat symptoms. Either Bupropion or Tramadol because of their dopaminergic effect do help although not all individuals may respond the same way. Have you tried them out?
JO

I have sent him a reply summarizing the reports found on the forum from those who have tried one of these two therapeutic alternatives ( I have not tried them myself).  Results have been mixed with bupropion.  Far less reports for tramadol, mostly positive, but not all.

Since he seems to be in favor of the role of dopamine in POIS pathophysiology, I asked him how he came to this view.

I also have thanked him for his interest and knowledge about POIS.   


It's great to see that there is at least one more doctor in the world that is aware of POIS and has even some relief options to offer !   

 

[demografx]

Great going, Quantum! How fast!

Hi again, Observer!

[demografx]

I just emailed Dr Komisaruk about Quantum's communication with Dr Osur.

Dr Osur wrote about a female POISer and I think that Dr K has done most of his orgasm research so far on women.

[demografx]

Also emailing it to Allison @ NORD.

[demografx]

https://rarediseases.info.nih.gov/diseases/10809/postorgasmic-illness-syndrome

[Quantum]

Great, Demo.  Poiscenter is listed in the "Organizations" tab.

[demografx]

Thanks, Quantum.

BTW, Stef deserves full credit for getting us listed at NIH!

[demografx]

But I never heard of "Post Orgasmic Sick Syndrome" before this.

[demografx]

http://www.mensjournal.com/health-fitness/articles/are-you-suffering-from-post-orgasmic-illness-syndrome-w448239

[Quantum]

http://www.mensjournal.com/health-fitness/articles/are-you-suffering-from-post-orgasmic-illness-syndrome-w448239

This freelancer may know Steven Blum, he has also written for Vice magazine, like Mr.Blum.  Good exposure for POIS, we will never have too much of it.

It would have been better still if he had mentioned poiscenter in his article, though.

[demografx]

I couldn't find the date when it was published. But it's great to see POIS in such a mainstream publication!

[Quantum]

I couldn't find the date when it was published. But it's great to see POIS in such a mainstream publication!

It is quite recent, because it cites the content of Dr Waldinger review article of 2016-07, him abandoning  desensitization, and stopping any reference to POIS as an allergy, and now describing POIS as "a systemic auto-immune reaction expressing itself in multiple physical and mental problems".  So this article has been out somewhere between August and November 2016.

The author seems to have had access to an interview with Waldinger after the review article was out, because he quotes him saying those things in his own words, not in the article's phrasing.  Anyway, these comments confirm what I have understood from his review article, and have shared here at http://poiscenter.com/forums/index.php?topic=2346.msg19538#msg19538  ( up on this thread you will also find the link to Dr Waldinger's July 2016 review article on POIS ).

There seems to be another snippet from this unknown interview when the article says, referring to desens, " Waldinger once tried to treat POIS (in two of the 45 Dutch patients suffering from the condition he’d identified) using a method designed to reduce allergy symptoms — which he credits with causing the POIS-as-allergy confusion. " ( my emphasis)   This sounds like the author have talked directly to Dr Waldinger, and that Dr Waldinger has somehow admitted that he is responsible for the inappropriate and limiting use of the word "allergy" when referring to POIS,  and that it should have been described from the start as a complex immune reaction, or a auto-immune overreaction.  By using desens to treat POIS, a method used to treat strictly allergic reactions, he have caused the confusion.  As I have already wrote, auto-immune diseases are not treated with desensitization, so the change in his view on POIS have called for a change in therapeutic strategy. 

So now that he clearly sees POIS as a auto-immune reaction, he must be searching for the antigen, the substance that causes the immune reaction, and eventually, the main markers that go up at the start of this overreaction.  If you can identify the first pro-inflammatory immune messengers to go wild, you will try to stop them at the very start, and then prevent the immune fire to spread everywhere in the body.  Auto-immune diseases manifest are flaring disorders, and in the case of POIS, you will have a flare each time you ejaculate.  A flare is more than just an allergic reaction, because it can go on long after the exposition to the allergenic substance is over, and new symptoms appear long after the start of the attack.  If you are allergic to cats, and you react to the presence of a cat, you will leave, go home, take an antihistamine, and the symptoms will slowly subside - no way you're going to be bed-ridden for a week and develop all sorts of systemic symptoms in the coming days - this type of complications is what happens with an auto-immune flare up, and that sounds a lot like what POIS is.


Let's hope Dr Waldinger finds the antigen and a few immune markers as well in his current study.

[demografx]

Quantum, do you think that the auto-immune theory is compatible with my effective personal choice of TRT treatment?