POIS Paper Archive - a list of scientific articles about POIS

[Muon]

This one slipped under the radar: https://apccm.in/wp-content/uploads/2022/05/Pulmon-2022-Jan-Apr-Final-Pdf.pdf#page=44

Histamine gives a larger flare than semen in the skin prick test. What does this mean?

[demografx]

This one slipped under the radar: https://apccm.in/wp-content/uploads/2022/05/Pulmon-2022-Jan-Apr-Final-Pdf.pdf#page=44

Histamine gives a larger flare than semen in the skin prick test. What does this mean?

Thanks. Sent to POIS Research Team.

[Marius]

Hey! I see that are some Atopic Dermatitis links, i read them but my english is not my first language, can somebody link a corellation from one or more of this studies with POIS?

[Muon]

Hey! I see that are some Atopic Dermatitis links, i read them but my english is not my first language, can somebody link a corellation from one or more of this studies with POIS?

I have posted a few articles that may shed some light on potential mechanisms in atopic dermatitis. There is no correlation with any of these (yet) because there is a lack of POIS research data. Atopic dermatitis shows up in a couple of POIS papers.

[demografx]

Hey! I see that are some Atopic Dermatitis links, i read them but my english is not my first language, can somebody link a corellation from one or more of this studies with POIS?

I have posted a few articles that may shed some light on potential mechanisms in atopic dermatitis. There is no correlation with any of these (yet) because there is a lack of POIS research data. Atopic dermatitis shows up in a couple of POIS papers.

Muon, could this possibly explain my bizarre dermatitis POIS reaction? All 10 fingertips go “nuts” on me. My dermatologist said there are hundreds of thousands of nerve endings there!

[Muon]

Muon, could this possibly explain my bizarre dermatitis POIS reaction? All 10 fingertips go “nuts” on me. My dermatologist said there are hundreds of thousands of nerve endings there!

It's possible that nerve endings communicate improperly with mast cells, the latter can be involved in dermatitis.

[demografx]

Muon, could this possibly explain my bizarre dermatitis POIS reaction? All 10 fingertips go “nuts” on me. My dermatologist said there are hundreds of thousands of nerve endings there!

It's possible that nerve endings communicate improperly with mast cells, the latter can be involved in dermatitis.

Thank you.

[Progecitor]

Muon, could this possibly explain my bizarre dermatitis POIS reaction? All 10 fingertips go “nuts” on me. My dermatologist said there are hundreds of thousands of nerve endings there!

It's possible that nerve endings communicate improperly with mast cells, the latter can be involved in dermatitis.

Some info that may be relevant in this interpretation.

As one of the principle mediators of innate immunity, mast cell (MC) functionality and population are affected by aging. The MC population was found to increase by 27% in mesenteric lymphatic vessels (MLVs) and with a 400% increase in activated MCs in the mesentery of the aged rats (24 months) compared to the younger control (9 months). It was concluded that this increase in MC population and activation in MLVs are essential for the degradation of the lymphatic vessels that occurs with age. Further, in healthy aged individuals (above 75 years), the MC population increased in the skin (papillary dermis) by 40% compared to the biopsies from younger individuals (less than 30 years), and dermal MCs associated more with macrophages and nerve fibers in aged skin compared to the younger samples. Interestingly, despite their increased presence in the papillary dermis, MC degranulation was significantly lower in aged skin, which might be explained by the reduced expression of the tachykinin precursor 1 (TAC1) gene encoding substance P, a neuropeptide that is also an MC activator in skin. Immunohistochemical staining of the eyelid and eyeball of the murine model of atopic dermatitis, Derm1NC/Nga mice, revealed that MCs increased significantly in the aged, diseased mice (10 and 16 weeks) compared to the younger (4 weeks) mice afflicted with atopic keratoconjunctivitis. Dexamethasone, an anti-inflammatory drug, reduced MC density in the eyeballs of these mice, demonstrating that manipulation of MCs may influence outcomes in age-related disease.
It was reported that although prostaglandin E2 (PGE2) is not a MC activator in younger mice, in older mice, PGE2 acts as a potent MC degranulation mediator for dermal MCs.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7650013/

[mike_sweden]

i had eczema as a child
having very dry and sensitive skin after orgasm

[Hopeoneday]

https://www.tandfonline.com/doi/full/10.1080/13685538.2023.2174511
Complementary role of Benson’s relaxation technique in post orgasmic illness syndrome.