Choline + Caffeine Combination for brain fog

[ThisType]

I've found that adding caffeine in smaller doses (I don't usually take caffeine) to my daily choline supplement improved the brain fog symptoms for me significantly. In doing a little reading, I came across some research that indicates improvement for short term memory using this combination. Anyone else experienced similar effects for memory or brain fog?

https://dsc.duq.edu/etd/967

TLDR: smaller doses of caffeine plus choline were helpful in short term memory. Larger doses of caffeine plus similar choline would impare it. The caffeine actually improves choline availability

[Hopeoneday]

Yess... https://poiscenter.com/forums/index.php?topic=3066.msg30643#msg30643

[Muon]

Low concentrations of caffeine raise intracellular calcium concentration only in the presence of extracellular calcium in cultured molluscan neurons

[Muon]

Postural orthostatic tachycardia syndrome

"Prognosis depends on aetiology. Patients may have continuous symptoms. They may be unable to cope with their employment or normal daily activities. After post-viral episodes around 50% of patients recover in 2-5 years. Prognosis is good in adolescent patients. In the majority >90% respond to a combination of physical methods as well as pharmacotherapy. In the hyperadrenergic state patients will require life long treatment. In the secondary form the causative disorder has to be treated in order for patients to become symptom-free.

Pyridostigmine, an acetylcholine esterase inhibitor, has shown promising results in the management of POTS caused by post-viral infection and autoimmune disorders.29 Low dose combination therapy is better than high dose monotherapy."

Emir Nazim had good results with Mestinon before he disappeared permanently from this forum (as others who showed good results with other meds and never heard from them again.)

[kakaw112]

Can say that it works for me a bit too. Warm coffee with milk gives me pimples generally but Cold coffee works for brain fog for me. I don't know what is happening. Can someone tell if I have MCAS or some exact form of POIS ?

[Hopeoneday]

Nac helped him then choline "cure":
https://www.reddit.com/r/POIS/comments/zfxkdl/pois_cured_and_heres_how_i_did_it/