Xanthiol Nicotinate - Benefits, Risks and Function in POIS

[sameer7777]

daveman .... what i know in energy drinks they use b1 , b6 b12 only u sure about b3 ??/
and still i dont get it should i get a 250 mg without flush or with flush ??//

jon , let us know pls ?

thanks u all

[Daveman]

Let the flush be the guide.

There are two imprtant and related factors. How much you have recently eaten and the strength of the flush.

For me, and it could be different for each person, if I haven't eaten for at least 6 hours, then 100mg gives me a good flush.
if I've eaten lke a sandwhich 2 hours before, then 200mg gives a good flush.
I still don't know how much I would need if I had just recently eaten.

A flush ISN'T absolutely required, but is a sure thing. Without flush, but thinking that I may have come close to the flush, I still have benefits, although protection on days 3 to 5 is not as strong.

The best is to try your first attempt first thing in the morning with 100mg. You should get a good flush. Don't take more than 100mg the first time until you see how you react.

[b_jim]

I have eaten lot of pasta yeterday and today I have body flush. I took only 40 mg of niacin one houre before orgasm.
From my opinion, moderate dose of vitamin B3 (20 to 120mg) CAN'T prevent flu-like symptoms. But  it may help with cognitive symptoms. And the vaso-dilatation effect theory is something interesting to explore.
I want to test claritin.

[sameer7777]

I bought the bottle of250 niacin for 20 dollars in my country
Wasted my money and time I took last night
The whole night I can't sleep and in the morning all my symptoms were stronger
Headache weakness and everything
I am very sad that niacin didn't help me

All of you bless you
Take care

[omen]

That's what I am trying to say...pois seems like shortage of sme chemical in the brain...niacin is a vitamin which helps people suffering through depression and serorin deficiency...an orgasm decreases the level of these useful chemicals inn brain...in normal people the level is not low that's why maybe they don't feel so upset the way we do because I think we poisers already have a shortage of these chemicals specially serotonin that's what I think...there's no allergy nothing...if medications given for serotinin deficiency work for us then maybe there's nothing like pois its just the chemical imbalance...
 
   

[Daveman]

That's what I am trying to say...pois seems like shortage of sme chemical in the brain...niacin is a vitamin which helps people suffering through depression and serorin deficiency...an orgasm decreases the level of these useful chemicals inn brain...in normal people the level is not low that's why maybe they don't feel so upset the way we do because I think we poisers already have a shortage of these chemicals specially serotonin that's what I think...there's no allergy nothing...if medications given for serotinin deficiency work for us then maybe there's nothing like pois its just the chemical imbalance...
 
   

I think you're pretty close in what you say. But what we need to know, is WHY are we deficient in this area. An auto-immune reaction could also lead to the same imbalance, as a result of excessive histamine production, or for some reason we can't adapt to regular histamine production, which can leave serotinine and dopamine low, or half a dozen other reasons.

So while we may be one step closer, there's still lots to figure out!!

[sameer7777]

Guys should I continue with niacin help me guys   ?

[omen]

Are u feelin better with niacin?if yes continue and if no then stop having it...

[Starsky]

I would give niacin another try. The first time i took it was not good.

[Habibou]

Did it change Starsky?
what was your 1st time and what did you change for the 2nd time? did you get relief?

[Daveman]

I find that the flush is important as a measure. You should try to get as close to a flush as possible, and hopefully it should be a good flush. I´ve had success without a flush, but I was always "close" to the flush. If the dose I took didnñt produce a flush I would take more in powdered form as soon as I knew that the flush wasn't coming. I use capsules, so it's easy to open one and take the powder directly. The powder enters the system faster.

What you eat before hand  makes a lot of difference. You should avoid eating for at least 2 hours beforehand.  Better is 4 or 6 hours. This is the biggest drawback, but WORTH IT.

Take the niacin BEFORE orgasm and don't have your orgasm until you have passed the initial flushed skin. You should wait until the "sunburn" feeling passes.

If you don't follow these steps, I think your success could be affected.

Sameer, did you get the flush?

[Habibou]

Thank you Daveman  I did that many times but I guess Niacin is just not the key for me !

[Starsky]

First i took too much. 1g XN, second time i took niacin but it wasnt perfect. with another tries was better.

[Habibou]

I only tried 500 mg of Niacin.
Perhaps it is too much and I should try 150 mg ?
It would be weird that it works with 150 mg and not 500...

[sameer7777]

No its not helping me at all !!!!

[Vandemolen]

Today I asked the doctor about Vitamin B3. He said that the reason why some of us find relief is because the flush runs out the histamines in the body. And when you have an O. the body will not spread histamines. And because of the histamines we have this allergy reaction. He said that maybe there is a risk the POIS gets worse because of Niacin. And you have to take a higher dose to get the same effect. And a lot of Niacin brings side effects as liver damage. BUT HE DIDN'T DO ANY RESEARCH ABOUT THIS! This is just his opinion. 

Niacin doesn't help me a lot. Maybe 10 to 20% less symptoms. I use 200 mg Niacin. I get a big flush. I do not dare to take more.
I found my relief in the injection therapy (50% less symptoms). But I told about that in another topic.

[Starsky]

We talked about this with Vincent. After a year of niacin usage his pois is at the same level. It didnt get better or worse due to niacin usage. He didnt noticed any tolerance to niacin, he gets always the same results with 150mg.

[Observer]

Today I asked the doctor about Vitamin B3. He said that the reason why some of us find relief is because the flush runs out the histamines in the body. And when you have an O. the body will not spread histamines. And because of the histamines we have this allergy reaction. He said that maybe there is a risk the POIS gets worse because of Niacin. And you have to take a higher dose to get the same effect. And a lot of Niacin brings side effects as liver damage. BUT HE DIDN'T DO ANY RESEARCH ABOUT THIS! This is just his opinion.  

Niacin doesn't help me a lot. Maybe 10 to 20% less symptoms. I use 200 mg Niacin. I get a big flush. I do not dare to take more.
I found my relief in the injection therapy (50% less symptoms). But I told about that in another topic.

I have been taking niacin since more than 100 days ago. I have been using the same amount (200 mg), and i am finding extraordinary relief or not POIS if properly taken. This has not changed, the only thing that is that the flush is more difficult to get after several days of continuous use.
I had the skin prick test on The Hague clinic and i took the niacin prior the test. My allergic reaction was very small, doctors said, and that could be explained by niacin.I wonder that other people here is having the same good results with niacin.

[Starsky]

Observer, they should do the skin prick without niacin too. I would say the red spot could be the same, because the theory about histamine storage that is being used is too simple. We get the same results with flush, without flush or even with flushfree niacinamide. I get always POIS whilse taking niacin, the only diference is that i dont get any cognitive symptoms or brainfog.Niacin helps our histamine deficiency. The flush is just your basophil and mast cells filling up with histamine. The dose it takes you to flush can help you determine your histamine levels. Niacin does not in fact induce a histamine release (which would make one wakeful): it induces a prostaglandin release (which does indeed slightly make one drowsy). Niacin flush being a result of histamine release is misinformation that has been floating around the internet.

[Observer]

Observer, they should do the skin prick without niacin too. I would say the red spot could be the same, because the theory about histamine storage that is being used is too simple. We get the same results with flush, without flush or even with flushfree niacinamide. I get always POIS whilse taking niacin, the only diference is that i dont get any cognitive symptoms or brainfog.

What are your other symptoms Starsky?

My brain fog is cleared, i do not get any brain fog or cognitive problems since i am taking niacin, and for sure that was the most awful symptom of my POIS.

Some other symptoms like my hair falling down, digestive problems for a day, sensitivity to light, bags under my eyes, etc ... i do not get this symptoms neither,except bags under my eyes, but not as they were used to be.