Testosterone

[Vandemolen]

Yes I also feel better after a good sleep or a nap. Sometimes I am awake after only 4 hours of sleep. Before I would stay in bed. But now I get out. Have breakfast and after an hour I take a nap.

I tried Rupatadine last year but it did not do anything.

[Muon]

I tried Rupatadine last year but it did not do anything.

Ok good to know.

[demografx]

I tried Rupatadine last year but it did not do anything.

Thanks, Van

[demografx]

I ordered Benadryl.

Van, this cautionary message is not for you, because I’m sure you understand the caveats. This is for other forum members, including newcomers:

1. I am not recommending Benadryl to anyone, I am simply sharing my own personal experience (everyone is different), after 10 years of combined TRT & Benadryl usage.

2. If you do decide to try it as “off-label usage” as I do (mostly for forcing extra sleep), please do not exceed the recommended dosage on the packaging.

[Muon]

The only antihistamine that had a minor positive effect on me was a first generation antihistamine. Tried 3 other antihistamines but those were second generation and didn't do anything. First generation penetrates the blood brain barrier. I think people should at least try both generations before discarding antihistamines.

[demografx]

Muon,
Were you using antihistamines for sleep induction or for direct treatment of POIS symptoms?

My entire discussion is about sleep induction.

[Muon]

Muon,
Were you using antihistamines for sleep induction or for direct treatment of POIS symptoms?

My entire discussion is about sleep induction. [Edited/added this line at same time as Muon reply was posted - Demo]

Direct treatment for POIS. But I just noticed this week that the only antihistamine that had an effect was first generation.

Edit: Does benadryl work when you avoid sleep, like skip naps during the day while on benadryl?

[demografx]

Does benadryl work when you avoid sleep, like skip naps during the day while on benadryl?

If I can’t sleep, Benadryl has a mild calming effect, thereby helping my POIS-induced anxiety.

My goal, however, is to only take Benadryl for (“extra”) sleep induction.

[G]

Hi all,
I like to tell you about my experience with testosteron-gel.
I suffer from POIS for 7 years now. my problems started after (I don't know if it is because if that) using Finasteride, and a long long time of chronic stress. Also sleeping problems and depression were there all those 7 years.

we measured T levels multiple times and they are always somewhere halfway the ref. values.

Even when the values were good, I asked to give it a try... now its 3 weeks after starting with the gel and al my weird problems are gone.
I feel energetic and motivated, my sleep is way better, my mind more clear and no feelings of depression anymore! POIS is gone for lets say 85% and especially the brainfog is almost totally gone! this is really insane.
.

G from the Netherlands.

[Muon]

we measured T levels multiple times and they are always somewhere halfway the ref. values.

Which of the following have you measured and what were the values?
Total Testosterone
SHBG
Free Testosterone

Edit: The reason I ask this is because Total T can be normal but free T low. Demo and some others already had a suspicion that TRT might help people with normal T levels.

I suffer from POIS for 7 years now. my problems started after (I don't know if it is because if that) using Finasteride, and a long long time of chronic stress. Also sleeping problems and depression were there all those 7 years.

Stress prior to the development of POIS...again. I have seen this so many times now, I have stopped tracking these. Bassett (2020) also reported this in literature.

[G]

we measured T levels multiple times and they are always somewhere halfway the ref. values.

Which of the following have you measured and what were the values?
Total Testosterone
SHBG
Free Testosterone

Edit: The reason I ask this is because Total T can be normal but free T low. Demo and some others already had a suspicion that TRT might help people with normal T levels.

we measured 3 times.
a while ago (2016):

total testosteron: 17.72 nmol/L-- ref: 8.6 - 29       free testosteron: 22.83 nmol/L -- ref: 7 - 25     SHBG: 38 nmol/L -- ref:17 - 52


6 weeks ago, before O and after O

before O: total testosteron: 21.7 nmol/L                             free testosteron : no value                                  SHBG: 52

after O: total testosteron: 17.4 nmol/L                                free testosteron: no value                                   SHBG: 50

latest measurement (with androgel after +-3 weeks) will come this week. i will keep you informed. that measurement includes also free testosteron.

problems are worse with the last measurement

[Muon]

Could you copy that to the results thread? You may put your first post in there as well for context.
https://poiscenter.com/forums/index.php?topic=2684.0

You can update your data there by modifying your post if new data presents itself.
What do you mean by 'problems are worse with the last measurement'?
Does 'no value' for free T means zero? I think Heather reported something similar if I remember correctly.

[G]

Could you copy that to the results thread? You may put your first post in there as well for context.
https://poiscenter.com/forums/index.php?topic=2684.0

i will do!

You can update your data there by modifying your post if new data presents itself.
What do you mean by 'problems are worse with the last measurement'?
Does 'no value' for free T means zero? I think Heather reported something similar if I remember correctly.

i will do!

That means : not measured.
I was at another doctor while asking for the measurement.
Here the doctor sends you to some place where they do the blood test, and till a year ago, you get a form from them and you see what they are going to test. Now you only get a barcode, so I was not aware of the fact that we did not a complete test.
the next test will be complete.

"What do you mean by 'problems are worse with the last measurement'?"

I mean that when I had these POIS problems back in 2016... it did not include sleepless nights after O. I was also able to drive a car safely and I did not have that much of depressed feelings. Also the timespan I had the problems was only like 24 to 48 hours. Till 3 weeks ago I was a depressed and emotional unstable zombie for at least 4 days and dropped stuff accidentally all day long. Bumped up to door openings, restless short nights, visiting the toilet for at least 4 times in the night etc etc. In short: i felt drunk and depressed, and not able to work or drive a car safely.

[demografx]

G, Your statement, “ Please give it a try”, was removed. Please see our forum rules @
https://poiscenter.com/forums/index.php?topic=1.msg10259#msg10259

“Do not use POISCenter as a substitute for, or to give, medical advice“

[demografx]

G, many thanks for your reporting!

After 10 years of testosterone patches, I’m reluctant to switch to gel, but you have provided teriffic information on your experience!

Thanks again.

[Muon]

G, Your statement, “ Please give it a try”, was removed. Please see our forum rules @
https://poiscenter.com/forums/index.php?topic=1.msg10259#msg10259

“Do not use POISCenter as a substitute for, or to give, medical advice“

Yes that's because TRT can lead to azoospermia for the people who don't know it yet.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241897/

[demografx]

The “no medical advice” rule was derived here in 2010 because any medical advice over the internet - - without specific patient-doctor evaluation - -  is inappropriate and potentially dangerous.

[demografx]

My POIS treatment is no longer available, due to a “shortage”. Endocrinologist asked me if I wanted to try the injection or gel route. I declined. After 10 years, I’m hoping my body has been “trained” somewhat, so I’m just going to tough it out with...nothing. Wish me luck.

The pharmacy just now called me and “found a 30-day supply”!

The plot thickens!

[aswinpras06]

Hi Demo

Does testosterone works for preventing your hot shower problem?

[demografx]

No, aswin, the only prevention I found is bird baths