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Author Topic: Testosterone  (Read 391010 times)

swell

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Re: Testosterone
« Reply #380 on: June 16, 2019, 04:43:15 PM »
In theory I believe Testosterone should work for everyone.  If you think about it, a) it is our sexual gland specific, Chief Hormone :)
b) just its behavioral effects are so evident, it makes you very confident, your muscles start to hulk up, you get that big energy boost, from being passive/timid you become dominant.  But that said, there are repercussions to taking TRT "well after" puberty.   But I also think if one can closely work with a doc and maybe take a tiny dose TRT before ejaculation and on limited basis?  Thats what I am doing with natural dissected thyroid, which also raises TRT and it is working at least as a nice bandaid.

Quote from: Nas on June 16, 2019, 02:50:37 PM
Hello comrades,
I've been wondering, dose TRT work for all the people who tried it? I've even seen some posts on FB and TRT always seems to work.
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POIS Free, 2+ yrs (occasional/predictive lapses)
Pois symptoms: Peripheral (Skin: Urticaria, dryness, pale blotchy skin), Exasperation of: [Nerve weakness, Muscle weakness + Mental (CNS: Brain Fog, Irritation, Isolation, Speech lethargy, Anxiety)].
Other conditions: ASD, ADD, GA

demografx

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Re: Testosterone
« Reply #381 on: June 17, 2019, 12:17:01 PM »

Thanks, swell & Nas!
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10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

Vandemolen

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Re: Testosterone
« Reply #382 on: July 03, 2019, 01:28:42 PM »
I have been to the urologist. He said my hot flushes and other symotoms could be caused by low testosterone. He said my testosterone is a bit low. My previous blood tests were taken in the afternoon. Next week I will do a test in the morning. If it is still the same then he wants to give something to stimulate my own testosterone. Not Clomid, something else.

He said he is seeing 4 POIS-patients. I told him about the succes of TRT. He said it is interesting, but he does not think it will take the POIS-symptoms away for 100%. He is trying anti histamine. He said 1 patient was helped by it. 1 a bit and 1 not at all.
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POIS since 2000. Very bad since 2008. I knew that I have POIS since June 2010. Desensitization since March 2011. I stopped with desens in July 2016. I have 50% less POIS. And only 1 day of POIS. Purified CBD works for me, but I am allergic for CBD.

demografx

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Re: Testosterone
« Reply #383 on: July 03, 2019, 02:04:35 PM »
Quote from: Vandemolen on July 03, 2019, 01:28:42 PM

I told him [my urologist] about the succes of TRT. He said it is interesting, but he does not think it will take the POIS-symptoms away for 100%.


Yes, this is true in my case.
« Last Edit: July 03, 2019, 03:16:50 PM by demografx »
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10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

Muon

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Re: Testosterone
« Reply #384 on: July 03, 2019, 02:39:24 PM »
Demografx, do you have problems with your blood circulation in general? I'm wondering whether testicular blood flow is allright.
« Last Edit: July 03, 2019, 02:41:17 PM by Muon »
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demografx

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Re: Testosterone
« Reply #385 on: July 03, 2019, 02:57:27 PM »
Muon, I don’t think so. Between my open heart surgery (5-way bypass) and very serious diverticulitis attack, I think my doctors would have seen something by now. I’ve been tested every which way :)
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10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

demografx

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Re: Testosterone
« Reply #386 on: July 03, 2019, 03:14:46 PM »
Quote from: Muon on July 03, 2019, 02:39:24 PM

I'm wondering whether testicular blood flow is allright.


It is (see my comment directly above), but you caused me to think of one of my several theories for my own POIS, i.e., POIS propensity due to the physiological *trauma* caused by doctors *repairing* my undescended testicle (1) at birth.
« Last Edit: July 03, 2019, 03:20:30 PM by demografx »
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10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

Nas

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Re: Testosterone
« Reply #387 on: July 03, 2019, 04:45:36 PM »

Guys, focus on these ====> [Neuropsychological symptoms]

Any theory discussed that doesn't explain these symptoms is inaccurate.
I feel by knowing what causes them we can trace it back accurately to its origin and even figure out the cause of POIS.
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demografx

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Re: Testosterone
« Reply #388 on: July 03, 2019, 05:19:58 PM »
I’m comfortable looking for possible causation without explaining neuropsychological symptoms.
« Last Edit: July 03, 2019, 05:27:06 PM by demografx »
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10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

Nas

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Re: Testosterone
« Reply #389 on: July 03, 2019, 05:40:41 PM »
It's an advise take it or leave it.
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demografx

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Re: Testosterone
« Reply #390 on: July 03, 2019, 09:53:25 PM »
Quote from: Nas on July 03, 2019, 05:40:41 PM

It's an advise take it or leave it.


OK, thanks.
« Last Edit: July 05, 2019, 10:31:22 AM by demografx »
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10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

demografx

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Re: Testosterone
« Reply #391 on: July 08, 2019, 07:18:59 PM »
Quote from: demografx on July 03, 2019, 03:14:46 PM
Quote from: Muon on July 03, 2019, 02:39:24 PM

I'm wondering whether testicular blood flow is allright.


It is (see my preceding reply to you), but you caused me to think of (1) one of my several theories for my own POIS, i.e., a POIS propensity due to the physiological *trauma* caused by doctors *repairing* my one undescended testicle at birth.

Might as well spill out (no pun intended) my other two POIS theories, developed since involvement in this forum since 2007. Please note: as the sophistication of this forum has grown significantly, I’m now much less wedded to these theories. In fact let’s just call them...notions :)

(2) semen regeneration speed - I don’t even remember what prompted this line of thinking, but I thought that POIS occurred as a result of slow semen regeneration. After ejaculation/depletion.

(3) excessive sexual frequency - in my 20’s. As one of our Forum bloggers username suggested: “too sexy for my body”! - I discussed this with one of the very knowledgeable forum members here and he dismissed the idea with “if that were true we would have *millions* and *millions* of POISers and the disorder would not be RARE.”

I have seen so many theories whizzing by since 2007 - including mine - and I am still...absolutely clueless as to what POIS is all about!
« Last Edit: July 10, 2019, 10:22:48 PM by demografx »
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10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

Nas

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Re: Testosterone
« Reply #392 on: July 08, 2019, 09:52:07 PM »
Can I offer my own theory?
If yes
After talking with many POIS doctors (three to be exact and one is still a medical student, I guess that's not many lol) I think I've come to a theory that POIS is mainly a neurological dysfunction specifically located in the limbic system ( this does tie in with the vagus nerve theory that you are recently very interested in). Even many of the physical manifestations like the flu like symptoms and the allergic symptoms can be due to this neurological dysfunction since many immunological behavior is connected to the CNS.
However Animus' case is a straight contradiction to this theory which may indicate that there are two types of POIS. Or I'm just outright wrong who knows. 
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demografx

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Re: Testosterone
« Reply #393 on: July 09, 2019, 09:30:10 AM »
Very interesting, Nas.
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10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

b_jim

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Re: Testosterone
« Reply #394 on: July 09, 2019, 02:54:02 PM »
Quote from: Nas on July 08, 2019, 09:52:07 PM
Can I offer my own theory?
If yes
After talking with many POIS doctors (three to be exact and one is still a medical student, I guess that's not many lol) I think I've come to a theory that POIS is mainly a neurological dysfunction specifically located in the limbic system ( this does tie in with the vagus nerve theory that you are recently very interested in). Even many of the physical manifestations like the flu like symptoms and the allergic symptoms can be due to this neurological dysfunction since many immunological behavior is connected to the CNS.
However Animus' case is a straight contradiction to this theory which may indicate that there are two types of POIS. Or I'm just outright wrong who knows.

Agree, but I think there is a metabolic paramter to explain the dysfunction of this area, horomone or neurotransmitter.
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Taurine = Anti-Pois

demografx

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Re: Testosterone
« Reply #395 on: July 09, 2019, 09:07:07 PM »
Thanks, b_jim.
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10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

demografx

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Re: Testosterone
« Reply #396 on: July 10, 2019, 11:53:25 AM »
Nas, very perceptive of u to recognize my recent re-awakening of interest in the vagus nerve theory. Just don’t ask me why ;D
Perhaps the upcoming research w/some deja vu of Hope. (Note the uppercase H :) ).
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10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

Nas

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Re: Testosterone
« Reply #397 on: July 10, 2019, 06:16:18 PM »
Quote from: demografx on July 10, 2019, 11:53:25 AM
Nas, very perceptive of u to recognize my recent re-awakening of interest in the vagus nerve theory. Just don’t ask me why ;D
Perhaps the upcoming research w/some deja vu of Hope. (Note the uppercase H :) ).
Perhaps that's what the last research doctor was so interested in this theory.
Also agree with b_jim that there could be a neurotransmitter dysfunction.
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demografx

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Re: Testosterone
« Reply #398 on: July 10, 2019, 09:04:30 PM »
Neurotransmitter dysfunction...maybe that’s why I’m on SSRI’s-for-life! If I stop taking them, I’ll cry nonstop in the elevator if someone accidentally drops a coin or a key.


« Last Edit: July 11, 2019, 12:24:11 AM by demografx »
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10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

Muon

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Re: Testosterone
« Reply #399 on: July 16, 2019, 04:21:15 PM »
''Our study has demonstrated that the testosterone deficiency increases cardiovascular risk via its effects on lipid metabolism and Lp-PLA2 can be used to assess this risk.''

The relationship between lipoprotein-associated phospholipase A2 with cardiovascular risk factors in testosterone deficiency
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832369/
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