The Taurine laboratory

[b_jim]

(only mcdouble and filet-o-fish burgers w/ OJ). And sushi train every second night. That was six years ago. Was it a high taurine diet?

I don't know how his the quality of filet-o-fish and sushi    ... but the more fish you eat and the more taurine you get. That's nice.

Today, I'm on Pois day 0 .  My energy is not 100% but I had a moderate activity witjout problem (painting...)   .Concentration is good, socialization is good......   Not possible  without taurine ! And tomorrow I know I will work with normal stamina.

--

As I wrote on my morning post, I wonder if we could improve the taurine effect by supplementing other amino-acids of the methylation chain. Or simply add garlic. I need to search recommanded dosage. 500 to 1500 mg a day might be a correct estimation.
(500 mg of taurine  + 500 mg of methinonine + 500 mg of cysteine ??)

[poison]

Well, Mondays are usually extremely difficult for me, but I prepared a small bottle of taurine water the night before and left it by the bedside so I could take a swig as soon as I got up (usually the worst time of the day). I woke up around 5-6am and felt pretty shithouse so I finished the bottle and went back to bed. Ended up sleeping till 7.15am and took around 10-15mins to get out of bed, normally on a monday I would take around 30-45 mins. Somehow I left the house on time and ended up at work early!

Before I left home I made a 600mL bottle with 1.6g of taurine in there, and took a swig every now and then at work. I would say my communication at work was around 80% but my ability to concentrate on desk work was around 30%. Its tough because I have to write 3 reports and review some SOPs.

Overall monday was 5/10, normally its 1 or 2/10 so that's an improvement. I haven't had a O for a few weeks now, but I did some "pre-O" 3 days ago and felt awful afterwards.

I would love to try more combinations of taurine with methylators, how about with SAM-e?

Regarding diet, I used to be a vegetarian and I see in wiki that the vegetarian intake of taurine can be as low as 0mg daily!

[b_jim]

Taurine may improve endorphins :
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC303613/?page=1

Endogenous opiate withdrawal syndrome after orgasm is an hypothesis.

[b_jim]

My yaurine bloodtest :

58   [37     127] : normal

After taking 500mg a day during one year, it's not really high.

[b_jim]

I didn't take taurine since some months now and it seems my Pois comes back.

Human semen :

Sperm taurine ranged from 17 nmol/mg DNA to 348 nmol/mg DNA, and hypotaurine from 0 nmol/mg DNA to 251 nmol/mg DNA. Seminal fluid contained 319 mumol/L to 1590 mumol/L of taurine, but no detectable hypotaurine.

How much taurine (in mg) in 1 ejaculation ?

Molar mass : 125.15g/mol
For the max value 1590mumol/L :

1 Lof semen => 0.00159 mol => 199mg of taurine
1 ejaculation ~ 5 ml
1 ejaculation => 0.995 mg ~ 1mg

mini : 1mg / 5  => 0.2 mg

1 ejaculation => 0.2 to 1 mg of taurine

--

Taurine is synthetized in the PANCREAS (and testes).

[Quantum]

I didn't take taurine since some months now and it seems my Pois comes back.

Hi B_jim,

Does that mean that you have been POIS-free for some months, even if not taking anything in order to prevent your symptoms?

[b_jim]

Yes. I had 2 ejaculations 2 days ago and yesterday I felt tired with the typical "Pois fever".
I will buy taurine soon.

[Going less Crazy]

I'm going to try and restart my taurine experiment as last time I tried it I was also taking other vitamins and herbs that I eventually stopped because they were causing symptoms.  Well today I took some turmeric/curcumin and I can confidently say that this is detrimental to my POIS.  Gives me a stimulant feeling. 

So during this stimulant feeling I decided to supplement with 500 mg taurine and it actually calmed me down.  So I'm going to try this stuff again.  Only taurine each day nothing else and I will update.

I hope I can tolerate this.  I've seen mixed reviews for sleep experience while on taurine but more positive than negative.  I also can use increased testosterone as that has helped some ppl and good for allergies and autoimmune disease.

Taurine also supposed to decrease hypothalamus inflammation in the brain from what I read.

[demografx]

2007 : start of the naked scientist forum. Demo and me joined 4 months after John's first message.

Time flies, b_jim!!

[Going less Crazy]

2007 : start of the naked scientist forum. Demo and me joined 4 months after John's first message.

Time flies, b_jim!!

Yes you guys are true POIS legends... Im sure books will be written about you . But you forgot that the mythic legend GoingCrazy joined not too long after.

But honestly thanks guys for all your POIS efforts I'm sure all of us are grateful.

[Going less Crazy]

B_Jim , how often can you O while on taurine without symptoms and have you ever experienced POIS while taking taurine?

I will update my taurine experience tomorrow.

[b_jim]

I'm not Pois free even with taurine but I feel much better.
Its' like Pois is a chain of symptoms and taurine cut the chain.

Just after ejaculation, I feel cold. My hands are cold and the blood stream is low.
But the hardest symptoms are suppressed or highly reduced : cognitive troubles, muscular energy, general stamina.

I have 1 to 5 ejaculations a week. Does the number of ejaculation influence the intensity of symptoms ? Yes, I think so.


I know you LOVE my beautiful draws

[Going less Crazy]

So I will need a couple more days to a week for an honest review of this stuff.  My hardest symptoms of POIS are the "brain" symptoms, hopefully these will be reduced.  I'm taking 500 mg taurine every morning.  I will O soon along with my typical remedies.  My problem is that I O too much which sometimes sets off symptoms.  I'm trying to lower frequency to once a week so it doesn't set off symptoms.

My grain free diet used to help me a lot but I don't know what exactly happened.  Last summer I could O pretty much freely without POIS.  So I'm trying to do what I did last summer which is a bit of grains in the morning.  But I also remember I drank almond milk instead of regular milk and some POIS members reported relief from not drinking milk.  I will also get back to drinking almond milk.

So again I'll update in a couple days to a week.

Ty for now for your experiments with taurine.  BTW how are your cognitive symptoms exactly when on taurine?  Do you feel POIS still to the point where let's say even existing is stressful, or can you still manage to work and be in a general good mood?

[demografx]

Nice graphic, b_jim!

[b_jim]

Thanks, Demo !

-

So I will need a couple more days to a week for an honest review of this stuff.

I think you are an anxious guy. Me too.  And then you are more sensible to placebo. You can take the 500mg all the day. They day you chose to ejaculate, maybe you can take the taurine just 1 hour before.

The risk of abusing of taurine is low.
500mg is the half of a can of energy drink. After 1 year of taurine (500mg a day) my blood test show a normal-low level 40ng/l [30-120]. 1 ejaculate is about 5-6 mg of taurine. Sometimes I speculate that I gradually depleted my taurine levels by ejaculation during my puberty (I ejaculated several times a week 1 year before my Pois come. And my symptoms came gradually.

It's possible that taurine supplementation take a little time to reload to normal level and then it decrease slowly when you stop to take it, explaining why my Pois symptoms seemed to come back after stopping taurine.

If you are skinny, maybe taurine will help you to gain weight (I have gain 5 kg in 1-2 years).
Taurine may improve fats absobtion by interresaction with the bile.
But the main activity

BTW how are your cognitive symptoms exactly when on taurine?  Do you feel POIS still to the point where let's say even existing is stressful, or can you still manage to work and be in a general good mood?

You have to knwo my WORST pois symptom is the cognitive symptom. In the past, I described this symptom by this expression "I feel like sleeping. I feel like in a dream". Dopamine or acetylcholine depletion I think.
Does taurine imrpoved this symptom ? YES.
But to be honnest, this symptoml has been reduced since 2008 when I stopped sugar.
Look again my draw. I wrote + for sugar and - for taurine.
I think the inflammation cause the symtoms.
When I stopped sugar I reduced inflammation and then symptoms.
Orgasm-> inflammation => symptoms
DAY0          DAY 0-1            DAY 1-3
If you reduced inflammation, the symtoms of day 1 to 3 are reduced.
Some guys have improvements with anti-inflammatory or anti histamines.
I thin it may work like this.

If you are stressed and later a bit depressed (and I think maybe you are), I'm not sure taurine will help you. But if taurine help you, you stress/depression will go out.

 

[Going less Crazy]

I'm not really an anxious guy outside of POIS I'm really laid back.  It's the POIS that causes certain symptoms, and these symptoms effect me very much.  I can go from 0 to 100 just from having an O (if either supplementation or diet hasn't worked in controlling POIS).

I'll make an early assessment of taurine.  As before I said I was having mid-pois symptoms and took curcumin/turmeric which seemed to have made it worse.  Than I took 500 mg taurine and felt more relaxed, less inflammation...

So after that I decided to take another 500mg and felt more hyper and couldn't sleep for most of the night.  The following morning I took 500 mg taurine and felt more hyper (probably bcuz I had more in me at the moment). But it was way better than POIS.  I've been taking 500mg every morning and the hyper reaction goes away in a couple hours and the total effects of that 500mg seem to take about 16 hours to leave my system, and when this happens I feel totally relaxed. 

Taurine is definitely a motivational pill and I practically painted my whole house while taking it.  There is something stimulating and calm about it, but it feels good and a drastic improvement from POIS. 

So last night I had an O after taking a taurine pill earlier that morning and it improved POIS a little bit but I still felt An anxious feeling that night.  But when I woke up this morning I took 250 mg taurine and the symptoms got way better and I've actually been painting again today and have much motivation.  I think I will stick to 250mg per morning for now.  Still haven't experienced taking taurine directly before O.  But during POIS it is a vast improvement in "brain" symptoms.

B_Jim I don't want to bum on your theory but I think we aren't deficient in taurine, rather this excess of taurine gets used effectively.  It increases dopamine and is found heavily in areas where the body is under inflammation to take that inflammation away (read that somewhere obviously).  So it is stimulatingly nice and takes away a good amount of inflammation.

Again, I will continue with 250mg just in the morning.  I also am trying to do what I did this summer when POIS seemed to vanish.  I'm substituting almond milk for regular milk and eating a tiny bit of Brown rice chex in the morning, other than that I am grain free.  I believe john21 said he found relief from avoiding milk.  I'll update sometime.

PS. I could use some weight gain but isn't taurine used as a weight loss supplement?  But I could also see this increasing strength training motivation and capacity.

[b_jim]

I have to admit that there are few people on this topic and then Taurine is not the universal cure
(5 testimonies only and only 3 seems very very convinced)

There is another proof that taurine is effective for me : I have no more ( at least much less) fasciculation.
https://www.youtube.com/watch?v=sVgQS_6iUGE
On this video, the guy has fasciculation only on his hand. I have fasciculation in "all" muscles on my body : legs, arms, back, chest.... even small muscle on skull
I have fasciculation all the time and especially after orgasm.
I saw a HUGE difference with taurine.
--
I started to take taurine after my experience with fish.
During several day, I ate fish (salmon) in large amount because I had a whole cooked salmon to finish.
I probably ate 1 kg or more fish during 3 days if I remember.
And I was surprised because I had no Pois symptoms.

So I tought there is something in fish helping my Pois.
I bought omega 3 oil, vitamine D, astaxanthine, vitamine B6.... nothing really helped like fresh salmon.
So, I tried taurine and I quickly find it improves my Pois.
--

PS. I could use some weight gain but isn't taurine used as a weight loss supplement?  But I could also see this increasing strength training motivation and capacity.

Maybe but all a lot of things are sold to lose weight.
Taurine give a real chance to improve fats digestion by bile regulation.

[demografx]

...you forgot that the mythic legend Going [less] Crazy joined not too long after [demo & b_jim].

How true! Sorry to omit you

[less_fogged]

Hi b_jim

Not sure where you got the quote but also want to add a confirmation to it:

I sometimes also get some fasciculation. -->Did not know this term!

Another thing, although probably already mentioned once: I'm not a regular taurine user but every time I use it within less than 12 hours after O it will help me reduce the annoying prickling sensation in my sex which will help me prevent re-lapse temptation. I can feel it's positive effects just for that part within 10/15 min after intake.
 
I fully agree that eating large quatity of FRESH salmon but especially when leaving it raw on the inside was reducing my cognitive symptoms quiet a lot.  Inflamation inside my chest is another story though.

Never tried it but guess eating 100% raw fresh salmon (not smoked obviously) would probably help quiet a lot

It would probably be interesting to have a scientific paper made on POISers using taurine.

[b_jim]

"the annoying prickling sensation in my sex which will help me prevent re-lapse temptation. I can feel it's positive effects just for that part within 10/15 min after intake."

Good point. For me it's more a restless legs symptom.
I couldn't say if I feel the positive effect 10/15 minutes later. It's not easy to say. But if you are right, it's maybe more the effect on nervous system than hormonal or immunologic system.