Author Topic: My POIS case and dizziness hell  (Read 1688 times)

steph33

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My POIS case and dizziness hell
« on: March 02, 2023, 10:11:44 AM »
Hi, I am new to this forum, I am 41 years old male and this is my short POIS story.

My pois started when I was around 20, and as I remember, it started with ?dizziness? the sense of being cloudy in my mind and not being present in reality. For maybe a year and a half I didn't know what was going on, I was depressed and desperate, I felt like a zombie and I could barely function. The symptoms would not stop and extended to include insomnia, visual fog, eye floaters, sensitivity to light, headaches, hortness of breath, ringing in the ears, mild nausea and general fatigue. I went to a bunch of doctors specializing in vertigo, but they couldn't find anything. When I went to another physiatrist who specialized in sleep disorders and talked to him about my constant dizziness, he asked me if I masturbate a lot and I said no! but that was the moment I realized what the hell was going on. In the following years, I gained some control over my symptoms: less frequent orgasms means fewer and milder symptoms and faster recovery, and vice versa. Sometimes the symptoms of dizziness appeared immediately, sometimes after a few days. Most of the time I would feel mentally exhausted and weak, I would sleep less, but without dizziness. If I overdid it with masturbation, I would get very dizzy and my right eye would get blurry - as a sure sign that I had overdone it). The dizziness symptoms would usually go away after a few days and I was fine. Other symptoms such as insomnia and fatigue were present, but they didn't bother me too much. Anyway, by controlling the frequency of orgasm I found a way to combat this horrible problem and I manage to control it until now.

In 2020. I got vitiligo.

In November 2021, I got corona. While I was recovering from lung problems, I had a weak orgasm, after which I got very dizzy. As usual, I started to abstain from orgasm and wait until the symptoms subside and disappear. But this time I couldn't recover, 7 days of abstinence...nothing changed...14 days...nothing, I was really scared. After these 14 days of abstinence, if I remember correctly I had a strong orgasm with my girlfriend and that washed away the dizziness and I was finally ok. After this terrible episode I decided that this would never happen again, I would start to recover my system with longer periods of abstinence and strengthen it so that after a while I could handle one orgasm a week.

So by September 2022. I was in a good rhythm of abstinence - streaks would range from 6 to 12 days depending on how I felt. Sometimes after orgasm I felt tired and had insomnia, but my worst symptom - dizziness was under control and my general condition improved. However, other problems appeared: due to prolonged abstinence my libido usually decreased, it would be harder for me to get excited, the erection would last less, as well as the quality of the orgasm. In August, I went on a 20-day of vacation, I felt very good, broke my abstinence and had an average of about three orgasms a week. The hot weather helped a lot, and my symptoms of dizziness and slight vertigo were rare and would deminished quickly.

Dizzines Hell

In September, instead of carefully starting a longer abstinence period, I had an orgasm every 4-6 days and after one weak orgasm I got more dizzy and that was the point from which I can't recover. For the next month and a half, I abstained for a maximum of 6-7 days, thinking that the good weather would make me recover faster, but it didn't work.
In October, after one great orgasm, the symptoms of severe dizziness mostly subsided, but only for a week, after which a bad orgasm brought me back to my previous situation. I realized that my resistance had decreased and I panicked. Despite the panic I thought I would surely recover, but now it will take more time.
In November I increased the duration of abstinence and tried to achieve one strong orgasm in between them. I abstained for 8-12 days, but abstinence didn't help at all. With longer abstinence, my libido dropped again and I couldn't get horny and achieve a satisfying orgasm, not even when I watched pornography, not even when I slept with my girlfriend. I started having frequent problems sleeping, but it didn't bother me too much. At the end of November, I went online to get information and found the POIS forums. I started using lots of supplements (vitamin C, D, B-complex, NAC, quercetin, lithium orotate, zinc, magnesium, ashwaganda, l-tyrosine, alkar, niacin rinse, etc.) but nothing immediately helped. My productivity at work decreased, I stopped going for long walks, I stopped sports activities, my anxiety increased, but I thought to myself that I would surely recover by Christmas.

In December I abstained twice for 14 days with one bad orgasm in between and nothing got better. I began to think that I had damaged my brain or had a brain tumor or destroyed my brain chemistry and was never going to recover. Now, being in that dizzy state for a long time, I think I could better describe the symptoms: slow eye focus, slight vertigo effect when my head moves faster, pressure and throbbing behind the eyes, visual fog between me and other objects, sensitivity to artificial light. Other milder symptoms sometimes include low concentration, slurred speech, cold feet, subtle vibrations in the body, and at times feeling nauseous. I couldn't figure out if anything other than orgasm was triggering my POIS symptoms now. I read a lot of stuff on poiscenter.com and POIS reddit, but the amount of information was too much for me to digest in this poor state.

In january 2023. nothing changed, I abstained for a periods from 8-14 days, got first nocturnal emision and still feeling dizzy all the time. I finaly went to my doctor and told her everything abouth POIS, gave her a print from the poiscenter.com but she wasnt interested.  She send me on different inspections?For now I  did EEG-everything is fine, arterya Collor doppler-fined, blood test ok with Iron one point below the line now.... I have to go to a neurologis.. test to hepatitis and do a lot of other stuff.
 
February 2023., no improvement, I am at the moment on the 26 day of abstinence and will try abstain as much as I can until the nocturnal emmision happens. I also started watching my diet and decided to reduce my intake of carbohydrates, artificial sugars and beer consumption(i forgot to mention that in may 2022. I made a small general Medical examination and was diagnosed with a fatty liver). Even though this ever-lasting condition exhausts and burdens me terribly and I constantly think about it, my desire to recover is still strong. I decided to write a letter and ask for any help, examination suggestion or advice from the forum members.

Quantum

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Re: My POIS case and dizziness hell
« Reply #1 on: March 02, 2023, 09:51:16 PM »
Hi steph33, and welcome to poiscenter :)

I think that a first step would be to follow your doctor advice and have your liver checked. The association of autoimmune hepatitis with vitiligo is well known, see https://pubmed.ncbi.nlm.nih.gov/28993983/.
 
Our liver is so very important for our health.  I wrote a detailed message about POIS and liver detoxification, some years ago, because in my case, I noticed that detoxing and helping my liver had lowered my POIS symptoms severity.  See my post at https://poiscenter.com/forums/index.php?topic=2431.msg20521#msg20521 for an explanation of the liver's functions in our body, and see at https://poiscenter.com/forums/index.php?topic=2431.msg21823#msg21823 for basic tips for improving liver health.  Even if your POIS is not totally related to your liver, helping your liver will help anyway.

Good natural products for a fatty liver are milk thistle, green tea, curcuma, and also lecithine.  I use all of these for my liver, and the first three for my POIS as well, and they are good for me.

Seeing a neurologist is a good thing since about all of your symptoms are neurological symptoms ( dizziness, brain fog, etc..).  At the least, you have to rule out another medical condition.





You are 100% responsible for what you do with anything I post on this forum and of any consequence it could have for you.  Forum rule: ""Do not use POISCenter as a substitute for, or to give, medical advice" Read the remaining part at http://poiscenter.com/forums/index.php?topic=1.msg10259#msg10259

Progecitor

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Re: My POIS case and dizziness hell
« Reply #2 on: March 03, 2023, 03:29:30 PM »
I don't specifically have NAFLD, but I generally had success with SIRT1 agonists (e.g. resveratrol, myricetin, lycopene) and CD36 antagonists (a long list at the link) and my POIS is evidently connected to lipid peroxidation.

The present study demonstrated that SIRT1 activation attenuated HFD-induced liver steatosis and inflammation by inhibiting CD36 expression and the NF-kB signaling pathway.
In addition, another study reported that SIRT1 expression was decreased in aged mice, whereas CD36 was upregulated, which could explain the increasing prevalence and progression of NAFLD associated with age in the general human population. The AMPK-mediated effects of SIRT1 have been reported to promote the deacetylation of PGC-1a, which then stimulates PPARA, leading to the initiation of CD36 transcription.
Studies have shown that CD36 contributes to the development of NAFLD by modulating the rate of free fatty acid uptake. Some researchers regard CD36 as a protective metabolic sensor in the liver during lipid overload or metabolic stress.

https://www.spandidos-publications.com/mmr/18/2/1609

Phytosterols can also help a lot by inhibiting lipid absorption.

Both phytosterols (beta-sitosterol and stigmasterol) significantly increased the expression of PPARA and decreased the expression of CD36. The lower intestinal bile acid levels would decrease the absorption of lipids from the diet, leading to the attenuation of body weight gain and lipid accumulation in liver. In addition, the lowered expression of CD36 caused by phytosterols may decrease hepatic uptake of fatty acid from the blood. Stigmasterol is more effective than beta-sitosterol in these actions, possibly through its decreasing the expression of some lipogenic genes and lowering circulating CM levels.
https://sci-hub.se/https://www.sciencedirect.com/science/article/abs/pii/S1388198118302038

I can't relate that much to the dizziness problem as it is not a common symptom for me. I only feel depressed most of the time without vertigo. However when POIS is combined with physical exhaustion due to work I feel like I am losing touch or the connection with my own body and I feel really dizzy at such times.

Contrary to dizziness photophobia is an everyday issue, even when not in the acute stage of POIS. Unfortunately I haven’t found the ultimate solution for that as of yet, but I suspect SIRT1 agonists to have a positive role as well.
Actually one of the other members called Enix also has Vitiligo and he used cortisone (prednisone) with some success to treat his photosensitivity.
https://poiscenter.com/forums/index.php?topic=503.20

Furthermore I found a recent study that associates Vitiligo with disturbed glucose and lipid metabolism and more generally with SASP which is the most likely cause of POIS as well. They also propose that Pioglitazone may revert the premature senescence phenotype partly through PPARG agonism and an increase in CD36 expression. Of course this partly contradicts the earlier hypothesis about SASP and yet it is clear that these factors must be the key in solving these diseases. I only wish I could test some of these drugs myself to shed some light on the matter, but doctors are not willing to prescribe me anything and this is not likely to change anytime soon.
https://www.mdpi.com/2073-4409/11/22/3583
The cause is probably the senescence of sexual organs and resultant inducible SASP, which also acts as a kind of non-diabetic metabolic syndrome.