Author Topic: drop24's complete remission of POIS for 1 year+  (Read 2438 times)

drop247

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drop24's complete remission of POIS for 1 year+
« on: October 23, 2023, 03:12:33 PM »
Hi guys,

I wanted to wait at least a year to post this to make sure my POIS was in fact in complete remission. I will post my regimen below which was heavily influenced by Demografx, a member I highly respect.

Regimen:
Escitalopram 20mg/day (this is an SSRI also known as Lexapro)
Testosterone Gel applied 3 times daily to scrotum
DHEA 100mg/day
Pregnenolone 100mg/day

That's it! Total remission and I can orgasm as much as I want. I try to do it at least 5 times per week just in case POIS is caused by some kind of prostate bacterial infection. If you want to know what my best guess is I would say we are just hypersensitive. The hormonal and neurotransmitter fluctuations after orgasm send our bodies into some kind of hypersensitive reaction. By taking the SSRI and exogenous testosterone these fluctuations are eliminated or at least highly reduced.

I should also mention that I also took Fenugreek seed capsules (2x610mg) before orgasm initially as this was one of my best go to treatments before starting the SSRI and hormonal treatment. I have since stopped taking the Fenugreek and my symptoms remain in total remission.

I had healthy testosterone levels before starting treatment by the way at around 600ng/dl. So I don't think POIS is caused by low natural testosterone levels. My treatment targets 1000ng/dl as ideal but sometimes falls below that into the 600-1000ng/dl range.

As you can imagine this has completely changed my life. My social anxiety is virtually gone and I'm working on mending all the relationships that have been damaged over the years by my condition.

Please ask me any questions you may have. I will check in periodically to see if I can help others.

Big thanks to Demografx for this forum and for inspiring my treatment regime!


demografx

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Re: drop24's complete remission of POIS for 1 year+
« Reply #1 on: October 23, 2023, 07:50:00 PM »

…influenced by Demografx, a member I highly respect…


…Big thanks to Demografx for this forum and for inspiring my treatment regime!


drop247:


ps - I also take Lexapro,
same dosage as yours.
« Last Edit: October 24, 2023, 12:53:40 AM by demografx »
10 years of significant POIS-reduction, treatment consisting of weekly (52 weeks/year) testosterone self-injections.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business.

Starsky

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Re: drop24's complete remission of POIS for 1 year+
« Reply #2 on: November 11, 2023, 05:13:17 AM »
Is the SSRI crucial in this treatment plan? pregnenolone and dhea you take once a day?

drop247

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Re: drop24's complete remission of POIS for 1 year+
« Reply #3 on: November 25, 2023, 10:34:13 PM »
Is the SSRI crucial in this treatment plan? pregnenolone and dhea you take once a day?

I can't tell because I started the SSRI and hormonal treatment around the same time. The SSRI has been life changing in terms of reducing my general anxiety though. I don't plan on stopping it anytime soon.

Yes, I take those once per day.

Warrior

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Re: drop24's complete remission of POIS for 1 year+
« Reply #4 on: November 26, 2023, 12:44:50 AM »
Great to hear you've found something that is working very well for you!
Disclaimer: Not medical advice. Consult professionals. Use at own risk.
My POIS Protocol | My YouTube Channel | POIS Subreddit

Dgf5

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Re: drop24's complete remission of POIS for 1 year+
« Reply #5 on: December 04, 2023, 12:23:27 PM »
Thanks for sharing.

Are you able to share brands of products you used? Is it safe to do this on own or did you work with doctor?

Thanks

drop247

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Re: drop24's complete remission of POIS for 1 year+
« Reply #6 on: April 20, 2025, 04:20:19 PM »
Escitalopram 20mg and Testosterone Topical Gel. I still have complete remission of POIS symptoms and can orgasm daily. I no longer take Pregnenolone or DHEA.

Aladin

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Re: drop24's complete remission of POIS for 1 year+
« Reply #7 on: Today at 06:36:10 AM »
thanks for keeping us updated !

freuemich

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Re: drop24's complete remission of POIS for 1 year+
« Reply #8 on: Today at 09:45:23 AM »
It's nice to know that you found something that works for you!

I think the Forum can benefit from some more information.

What were your symptoms? Can you describe them in detail here?

I'm specially interested about the cognitive symptoms.

What were they and how intense/debilitating?
How long did they last?
Did you have noise sensitivity?


Another important info we need: can you specify the gel you are using? The info about the miligrams of testosterone contained is very important.
« Last Edit: Today at 02:53:18 PM by freuemich »