Author Topic: Decreased estrogen leads to POIS? Inspiration and dysmenorrhea  (Read 360 times)

Lihua

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    • a Chinese man's case and situation of all the POISers undergoing desenz in China
        We know that one patient cured POIS by taking norethisterone, https://my.clevelandclinic.org/health/diseases/8260-menstrual-migraines-hormone-headaches  and   https://www.healthline.com/health/headache/headache-during-period#causes  shows that "After ovulation (the release of an egg from the ovary), hormone levels decline. Estrogen and progesterone levels are at their lowest right before your period. It’s this decrease that makes some women more likely to experience headaches.","Headaches in women, especially migraines, are related to changes in the levels of estrogen. Levels of estrogen drop immediately before the start of your menstrual flow (menses).Premenstrual migraines regularly occur during or after the time when the female hormones, estrogen and progesterone, drop to their lowest levels.Migraine attacks usually improve during pregnancy. However, some women have reported that their migraines started during the first trimester of pregnancy, and then went away."
      On the other hand, in men, estrogen can also be produced by testosterone, maybe it is connected with the problem that why HCG and TRT can help, As far as I am concerned, non steroidal anti-inflammatory drugs and glucocorticoids can greatly alleviate my symptoms. These two drugs are also used to treat menstrual headache, which leads us to wonder whether POIS is related to estrogen?
     OK guys, how do you like it? Be as free and open as you wish :)
all Chinese can send me a personal message, I have a wechat group. There are doctors researching POIS in Guangzhou, Beijing, Harbin.

VSmasher

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Re: Decreased estrogen leads to POIS? Inspiration and dysmenorrhea
« Reply #1 on: June 28, 2022, 06:06:33 PM »
        We know that one patient cured POIS by taking norethisterone, https://my.clevelandclinic.org/health/diseases/8260-menstrual-migraines-hormone-headaches  and   https://www.healthline.com/health/headache/headache-during-period#causes  shows that "After ovulation (the release of an egg from the ovary), hormone levels decline. Estrogen and progesterone levels are at their lowest right before your period. It’s this decrease that makes some women more likely to experience headaches.","Headaches in women, especially migraines, are related to changes in the levels of estrogen. Levels of estrogen drop immediately before the start of your menstrual flow (menses).Premenstrual migraines regularly occur during or after the time when the female hormones, estrogen and progesterone, drop to their lowest levels.Migraine attacks usually improve during pregnancy. However, some women have reported that their migraines started during the first trimester of pregnancy, and then went away."
      On the other hand, in men, estrogen can also be produced by testosterone, maybe it is connected with the problem that why HCG and TRT can help, As far as I am concerned, non steroidal anti-inflammatory drugs and glucocorticoids can greatly alleviate my symptoms. These two drugs are also used to treat menstrual headache, which leads us to wonder whether POIS is related to estrogen?
     OK guys, how do you like it? Be as free and open as you wish :)

Interesting Lihua. I wonder if taking a supplement like black cohosh to increase estrogen would help?

I notice when I take alfalfa (which is loaded with phytoestrogens) it seems to help my pois. Alfalfa also makes me Horner than a Billy goat.

I'm gonna look into this. Thanks brother
My POIS Symptoms:  Brain Fog, frustration, stuffed nose, anger, anxiety, intense hunger, low self esteem, swollen face, and feel zoned out.

Progecitor

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Re: Decreased estrogen leads to POIS? Inspiration and dysmenorrhea
« Reply #2 on: July 05, 2022, 02:28:36 PM »
        We know that one patient cured POIS by taking norethisterone, https://my.clevelandclinic.org/health/diseases/8260-menstrual-migraines-hormone-headaches  and   https://www.healthline.com/health/headache/headache-during-period#causes  shows that "After ovulation (the release of an egg from the ovary), hormone levels decline. Estrogen and progesterone levels are at their lowest right before your period. It’s this decrease that makes some women more likely to experience headaches.","Headaches in women, especially migraines, are related to changes in the levels of estrogen. Levels of estrogen drop immediately before the start of your menstrual flow (menses).Premenstrual migraines regularly occur during or after the time when the female hormones, estrogen and progesterone, drop to their lowest levels.Migraine attacks usually improve during pregnancy. However, some women have reported that their migraines started during the first trimester of pregnancy, and then went away."
      On the other hand, in men, estrogen can also be produced by testosterone, maybe it is connected with the problem that why HCG and TRT can help, As far as I am concerned, non steroidal anti-inflammatory drugs and glucocorticoids can greatly alleviate my symptoms. These two drugs are also used to treat menstrual headache, which leads us to wonder whether POIS is related to estrogen?
     OK guys, how do you like it? Be as free and open as you wish :)

Be careful if you decide to test Norethisterone as it mostly activates ERalpha while it only has a little effect on ERbeta.
https://academic.oup.com/endo/article/142/9/3791/2988944?login=true
As it was explained earlier this could potentially worsen an ongoing prostatitis.
https://poiscenter.com/forums/index.php?topic=4104.msg45009#msg45009
Some POISer may feel better from it, but others also had negative reactions.
https://poiscenter.com/forums/index.php?topic=3551.msg38645#msg38645

Interesting Lihua. I wonder if taking a supplement like black cohosh to increase estrogen would help?

I notice when I take alfalfa (which is loaded with phytoestrogens) it seems to help my pois. Alfalfa also makes me Horner than a Billy goat.

I'm gonna look into this. Thanks brother

Previously it was shown that alfalfa has a higher affinity for ERbeta than ERalpha.
https://poiscenter.com/forums/index.php?topic=4061.msg43325#msg43325
(ctrl+f: alfalfa)

It was also shown that alfalfa is considered an uncommon remedy for the management of prostatitis.
https://poiscenter.com/forums/index.php?topic=4196.msg44916#msg44916
More specifically:
ECLECTIC TREATMTENTS FOR BENIGN PROSTATIC HYPERPLASIA (BPH)
The Eclectics called this condition chronic “prostatitis.” It was associated with aging men as it is today.
Alfalfa Leaf (Medicago sativa)
Indications: Prostatic irritation in the elderly.
Dose: Tea: 1 teaspoon herb, 8 oz. hot water, steep 45 minutes, take 4 oz. QID

https://www.americanherbalistsguild.com/sites/americanherbalistsguild.com/files/sample-articles-pdfs/eclectic_therapeutics_for_the_male_reproductive_system.pdf

If I consider senescence as the underlying issue than it is no wonder that I have chronic prostatitis just like that of an old man even though everything started in my early teenager years.

Black cohosh is also mentioned in the earlier article.

Enlarged Prostate with Irritation
Wintergreen Tincture: 20 gtt
*Poke Tincture: 10 gtt
Black Cohosh Tincture: 20 gtt
Glyconda
Mix with 4 oz of water, take 1 teaspoon QID


Black cohosh is also considered a SERM, although it doesn’t appear the bind strongly with either of the estrogen receptors, although another study claims otherwise. Most interestingly it is also a partial agonist of the serotonin and the mu-opiate receptors which may make it somewhat similar to Zembrin (kanna).
https://poiscenter.com/forums/index.php?topic=4061.msg43325#msg43325
(ctrl+f: cohosh)
The cause is probably the senescence of sexual organs and resultant inducible SASP, which also acts as a kind of non-diabetic metabolic syndrome.

VSmasher

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Re: Decreased estrogen leads to POIS? Inspiration and dysmenorrhea
« Reply #3 on: July 17, 2022, 09:55:33 PM »
Alfalfa does help my POIS but it also gives me NOCTURNAL emish. I get like 4 NOCTURNAL emish in a row when I get them. I don't just get one. It's strange..
My POIS Symptoms:  Brain Fog, frustration, stuffed nose, anger, anxiety, intense hunger, low self esteem, swollen face, and feel zoned out.

Progecitor

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Re: Decreased estrogen leads to POIS? Inspiration and dysmenorrhea
« Reply #4 on: July 23, 2022, 05:32:49 AM »
Alfalfa does help my POIS but it also gives me NOCTURNAL emish. I get like 4 NOCTURNAL emish in a row when I get them. I don't just get one. It's strange..

Have you had a similar experience with Maca or Tongkat Ali? Is there a particular reason you are not using them? Have you tried to combine Maca and Kanna with any noticeable benefit?

In the meantime I have also tried black cohosh and it proved relatively useful even if not to the degree of maca or tongkat ali. This at least questions the solitary role of testosterone.

Regarding alfalfa I don’t think I have experienced any NEs so far, but prolonged intake may cause a symptom I call ass muscle inflammation, which I know sounds quite silly, but I simply can’t define it more properly. I had some really severe cases of it in the past without taking any supplements. It may be interesting to note that at least on a few of those occasions I remember having NEs. These NEs of course induced POIS, however most unusually they also ameliorated the earlier mentioned inflammation and set it on a course of resolution in the following days. On those occasions it felt much like my body was instinctively trying to induce an NE to resolve this pain and later I actually developed a habit to voluntarily O just to try to resolve the issue.

I am also quite sure that zinc can induce the earlier mentioned symptom. Do you have any experience with zinc?
The cause is probably the senescence of sexual organs and resultant inducible SASP, which also acts as a kind of non-diabetic metabolic syndrome.