Hi, I owe you this guys, so here it is. (TL;DR at bottom)
This is a continuation to my previous thread, I'm making a new one because as of now I feel almost 100% symptom-free and it's getting better and better.
Previous thread:
http://poiscenter.com/forums/index.php?topic=2455.msg21396A few weeks ago, in addition to my already ongoing 4-5 months of testosterone replacement therapy I've started dosing low dose naltrexone.
Here's good info:
https://www.lowdosenaltrexone.org/It works for quite a lot of diseases, mechanism isn't really known. What interested me was that rather than naltrexone doing the healing, it kinda "pushes" the body to do the healing itself. It turns on some healing mechanisms, tickles them so they start working like they should. This is very simplified explanation. Other things that interested me is that it seemed to work similarily to BPC-157 that I've previously tried and that was somewhat successful for me (not fully, though).
Anyways. TRT helped me feel much better emotionally. I was no longer an emotional wreck after orgasm and I could orgasm more often. I no longer have trouble gaining weight. Et cetera. Not gonna list all the feels where TRT helped me.
Instead, where it didn't help me was: general fatigue, and after-orgasm fatigue. After-orgasm burning eyes. Diarrhea, gluten sensitivity, milk sensitivity, I still had fucked up gut. I was also still dissociated after orgasm, and in general.
Interestingly, LDN is also used in dissociative disorders. And in celiac disease (gluten intolerance). And hormonal imbalances! I often had to pee very often because of sodium imbalances in my body. I had to drink a lot of salt water to keep up.
LDN started working the very first couple days - I had a single ejaculation shortly after starting, then I went across the country to my friend, and I haven't noticed any symptoms. In the first couple weeks of dosing 4.5mg every night, I had some blood in my stools. I was prepared for it. It was said that during LDN therapy the first couple weeks you can actually feel worsening of symptoms. I didn't, I just had blood in my stools. People who also self-medicated with LDN on the Internet said they'd take a couple days break every time blood appeared. I had a single day break here and there, just randomly because I had forgotten LDN. The blood is gone though, it's been over a week since I've last seen it in my stools.
Now onto how it works for me. I used to have worsening of symptoms every time I ate gluten or milk, also when on TRT. Or even proteins. Or even just food in general... Sometimes it felt really random. However always after gluten I'd have burning eyes back, and fatigue of that kind where I'd better take a nap if I wanna be productive. No more.
I'd have loose stools often. No more. Since taking LDN, all I get are healthy, solid stools that leave little to no wiping & cleaning (lol). This is a huge change. I feel like a teenager again, when I had always healthy gut.
I barely have any fatigue. I used to have this blood sugar (or something, will never find out, it's not worth it) problem, where if in the morning I didn't eat anything and I went to do some activity first, before eating, like going shopping for food. When I came back I'd be very fatigued and weak, nauseous etc., I'd have to eat ASAP. I was always avoiding this issue by breakfast first thing in the morning. However later in the day, any longer than a couple hour fast was giving me fatigue. Not as intense as in the morning, but intense enough to direct my focus onto
you have to eat right now and you have to prioritize this. No more. Granted, I haven't tested longer fasts. However I see that I am nowhere as weak as I used to be when I don't eat for some time. I haven't tested in extensively by eg. fasting for a whole day. However I've already had a few situations where I haven't eaten for a few hours and I was fine. I was just hungry. A little weaker because of no carbs, but nowhere as fatigued as I used to be.
Orgasms. In the last week, I must have had almost two dozens of them. Haha, almost, but still a lot. My LTR and I have got "Back" together and we live very close to each other. So we've had sex every day for the last 7 days, every day would average to 2-3 orgasms. Therefore something between 14 and 21 ejaculations.
Now here comes the "almost 100% cured" part. 3 ejaculations ago I've had a weak POIS reaction - just burning eyes and a bit of fatigue, all in all maybe 5-10% of what it used to be. It lasted half a day. After sleep I haven't felt it. However, I think for most of you 2-3 ejaculations a day for a week is more than you ever wished for. Actually, I think a completely healthy person, if he ejaculated that many times in a week he'd be fatigued. So I don't think it's bad. Especially that post after every other ejaculation I felt completely fine.
I think it's amazing. For the first time in years I can choose whether I want to ejaculate or not, without "having to" not ejaculate. It's freedom for me. I no longer dread a whip behind me, punishing me everytime I wanted to do what felt natural and healthy for me. Now I can finally choose for myself. And it's a worthwhile choice, coz if you orgasm too much, you get lazy and complacent a bit, haha.
It's gonna get even better, coz it's only been few weeks. I hope not to have take this until the end of time, however, if I do have to, I don't mind, because...
LDN and TRT are extremely cheap.
I buy testosterone in the gray market and for TRT purposes, 70mg of enanthate weekly does the job well for me. It puts me in 1000ng/dL ~ range, together with syringes, this costs barely anything. The bottles I buy from steroid underground labs are usually dosed 250mg/ml, for quality 10ml vial I pay about 40$. Anyways, monthly cost sums about 3-4$. Yup.
Naltrexone is also cheap, because we're not using it in standard 50mg doses, but 4.5mg daily, which is 10x times less. I also buy those on my own. 3 tablets (3x50mg = 150mg / 4.5mg = 33,3 days, supply for a month) cost me about 5-8$.
Total cost of my treatment monthly: 12$ at worst.
In my fifth world country that is Poland I don't hope for finding a doctor that'd prescribe me all this. See, doctors don't like when you're being smarter than them at something. Especially when you're treating an illness that doesn't exist to them with off-label medications that are used for completely different purposes. I don't give a shit. I'm glad I took the matters in my own hands. I am well-versed in sourcing this stuff and I doubt I'd ever have any troubles finding testosterone or naltrexone in the gray/black market. Naltrexone is a bit worse, because it isn't used recreationally and isn't very popular. However I'm buying it from some guy who is also doing LDN therapy. And then, if I didn't have it for a couple weeks I don't think it'd be very problematic - only TRT is problematic, because once you start TRT, your body is addicted to exogenous testosterone. That's it.
Again, I'm glad I took the matters in my own hands, because a) I have no money for doctors, b) I don't trust doctors more than I trust myself, especially when an endocrinologist tells me 245ng/dL testosterone is "in range and fine for my age", c) I am confident in my ability to find solutions like those that I've found - I have the drive to learn, research papers, test myself and let my knowledge and intuition guide me. This healing took well shorter than if I were going to the doctors and hope for the best, instead I had full responsibility for my health in my hands. No handing that over to someone else that I don't know.
I'm not saying all doctors are shit. But if I were to collaborate with a doctor, he'd have to be my personal friend outside of doctor-patient relationship. I'd have to know he takes criticism and that he keeps studying and expanding his knowledge. I'd have to know he's the bold, determined type. I feel that way and I expect the same from people I collaborate with, otherwise we're not at the same level and we won't enjoy the teamwork. Hey, I might just post an ad... Looking to befriend a doctor. Lol
Last but not least, a week after I've started LDN (and few days after an orgasm with no symptoms) I've had a "healing session". The woman knew about my illness and I've talked to her. Now I neither believe or disbelieve in energy stuff. I've neither helped nor stood in the way of her. Basically, she said I have blocked sexuality and so on, and she was healing through touch. Whole session lasted about an hour together with asking/telling the story. It helped me feel better about not constraining my sexuality and also I've found out I can talk with my dead father. It is as weird for me to say that as it is unusual for you to read. And you may not believe it, but that's what happening. Since the healing session was directly about POIS, I thought it might be worth mentioning, though I felt fine even before the session.
TL;DR: 4.5mg low dose naltrexone daily together with a bit of TRT (because I had low T) and I can orgasm freely even dozen times a week.Go and try out LDN therapy. It costs little, there's a lot of research behind it, and there's nothing to lose. You either benefit from it or not. I haven't read about any cases of worsening the symptoms. Even if your POIS type isn't hormonal it could help you out. With all the research on LDN, we know very little about it.
Use my experience for yourself. I wish you all the best guys.