POIS treatment: theory & supplement stack

[itsmel]

Ok so you took excerdrin instead of Paracetamol, indomethacin and caffeine? In The Netherlands you need a doctor’s prescription for indomethacin. But excerdrin is for sale.

Yes, since I would need to buy different products for Paracetamol, indomethacin and caffeine.

1. Tylenol (Paracetamol)
2. Ibuprofen (Indomethacin)
3. Caffeine

All these are also available over the counter.

I just instead take Excerdrin which also includes Caffeine. This stack is strictly for PE.

[Vandemolen]

Ok so you took excerdrin instead of Paracetamol, indomethacin and caffeine? In The Netherlands you need a doctor’s prescription for indomethacin. But excerdrin is for sale.

Yes, since I would need to buy different products for Paracetamol, indomethacin and caffeine.

1. Tylenol (Paracetamol)
2. Ibuprofen (Indomethacin)
3. Caffeine

All these are also available over the counter.

I just instead take Excerdrin which also includes Caffeine. This stack is strictly for PE.

Oh ok I don’t have PE or NE. So then I don’t have to take these 3 medicines?

[Vandemolen]

I just bought the medicines from the prepack. And Excerdrin instead of those 3 medines. I hope to start wednesday with the stack. And I will take it at least 10 days before I test it.

My question is: can I keep taking other supplements like Zinc. I take Zinc for my prostate problems. Not sure if it helps. And also cefuroxim.

[itsmel]

Ok so you took excerdrin instead of Paracetamol, indomethacin and caffeine? In The Netherlands you need a doctor’s prescription for indomethacin. But excerdrin is for sale.

Yes, since I would need to buy different products for Paracetamol, indomethacin and caffeine.

1. Tylenol (Paracetamol)
2. Ibuprofen (Indomethacin)
3. Caffeine

All these are also available over the counter.

I just instead take Excerdrin which also includes Caffeine. This stack is strictly for PE.

Oh ok I don’t have PE or NE. So then I don’t have to take these 3 medicines?

If you don't have PE, it's not necessary to take Excerdrine although it might still benefit you if you know what I mean.

[itsmel]

I just bought the medicines from the prepack. And Excerdrin instead of those 3 medines. I hope to start wednesday with the stack. And I will take it at least 10 days before I test it.

My question is: can I keep taking other supplements like Zinc. I take Zinc for my prostate problems. Not sure if it helps. And also cefuroxim.

Ok, wish you the best of luck.
Btw, do you happen to know if you have MTHFR? I have not read the whole thread so I don't know if the stack can respond to people with non-mthfr issues.

Not sure about the interactions between the stack and zinc/cefuroxim.

[Quantum]

Hi,

I just want to report in that nanna1 POIS stack works for me. Bear in mind that I do have an issue with MTHFR where person cannot optimally process folate (B9).
 
(...)

It seems to me that this stack only works with people who have MTHFR issues so therefore it will not work for everyone.

Thanks nana1.

Hi itsmel, and welcome to the forum !   

I tend to agree with your opinion that Nanna's stack works with people having a MTHFR issue, and not necessarily with others.  That is the reason why I have placed in the "Methylation support" section of my POIS Types Chart ( http://poiscenter.com/forums/index.php?topic=2338.msg19448#msg19448)

[Vandemolen]

I just bought the medicines from the prepack. And Excerdrin instead of those 3 medines. I hope to start wednesday with the stack. And I will take it at least 10 days before I test it.

My question is: can I keep taking other supplements like Zinc. I take Zinc for my prostate problems. Not sure if it helps. And also cefuroxim.

Ok, wish you the best of luck.
Btw, do you happen to know if you have MTHFR? I have not read the whole thread so I don't know if the stack can respond to people with non-mthfr issues.

Not sure about the interactions between the stack and zinc/cefuroxim.

Thanks! I don’t think I have MTHFR. Never heard about it haha. I will google it to see what the symptoms are. Does Nanna have MTHFR? Vitamin B9/11 is bad for MTHFR but it’s in Nanna’s stack. A bloodtest for MTHFR costs more than 600 euro.

[dizzy]

Does Nanna have MTHFR? Vitamin B9/11 is bad for MTHFR but it’s in Nanna’s stack. A bloodtest for MTHFR costs more than 600 euro.

According to what I've read, with a dysfunctional MTHFR gene you have to take the right form of folate, which is methylfolate.

Some people determine if they have MTHFR problems through a genetic test like offered by 23andme. However, this only tests a selected number of SNPs (=locations of the gene), so in theory your copies of the gene could be defective even if the test says they are not. On the other hand, if the test says you have defective MTHFR genes, then you can be sure that you have a problem there.

[itsmel]

Hi itsmel, and welcome to the forum !   

I tend to agree with your opinion that Nanna's stack works with people having a MTHFR issue, and not necessarily with others.  That is the reason why I have placed in the "Methylation support" section of my POIS Types Chart ( http://poiscenter.com/forums/index.php?topic=2338.msg19448#msg19448)

Thanks!

[itsmel]

Does Nanna have MTHFR? Vitamin B9/11 is bad for MTHFR but it’s in Nanna’s stack. A bloodtest for MTHFR costs more than 600 euro.

According to what I've read, with a dysfunctional MTHFR gene you have to take the right form of folate, which is methylfolate.

Some people determine if they have MTHFR problems through a genetic test like offered by 23andme. However, this only tests a selected number of SNPs (=locations of the gene), so in theory your copies of the gene could be defective even if the test says they are not. On the other hand, if the test says you have defective MTHFR genes, then you can be sure that you have a problem there.

That's correct.
The simplest way to check for MTHFR issues is through 23andme testing service and then have it run through genetic genie.

http://geneticgenie.org/

[itsmel]

I just bought the medicines from the prepack. And Excerdrin instead of those 3 medines. I hope to start wednesday with the stack. And I will take it at least 10 days before I test it.

My question is: can I keep taking other supplements like Zinc. I take Zinc for my prostate problems. Not sure if it helps. And also cefuroxim.

Ok, wish you the best of luck.
Btw, do you happen to know if you have MTHFR? I have not read the whole thread so I don't know if the stack can respond to people with non-mthfr issues.

Not sure about the interactions between the stack and zinc/cefuroxim.

Thanks! I don’t think I have MTHFR. Never heard about it haha. I will google it to see what the symptoms are. Does Nanna have MTHFR? Vitamin B9/11 is bad for MTHFR but it’s in Nanna’s stack. A bloodtest for MTHFR costs more than 600 euro.

No blood test needed.
23andme testing cost 100$ USD then genetic genie for free.
http://geneticgenie.org/

[Vandemolen]

Does Nanna have MTHFR? Vitamin B9/11 is bad for MTHFR but it’s in Nanna’s stack. A bloodtest for MTHFR costs more than 600 euro.

According to what I've read, with a dysfunctional MTHFR gene you have to take the right form of folate, which is methylfolate.

Some people determine if they have MTHFR problems through a genetic test like offered by 23andme. However, this only tests a selected number of SNPs (=locations of the gene), so in theory your copies of the gene could be defective even if the test says they are not. On the other hand, if the test says you have defective MTHFR genes, then you can be sure that you have a problem there.

“Methylfolate is a remarkable nutrient yet it can create significant side effects. Those who have MTHFR mutations (especially the C677T MTHFR mutation) learn that methylfolate is critical to take.”
http://mthfr.net/methylfolate-side-effects/2012/03/01/

[itsmel]

Does Nanna have MTHFR? Vitamin B9/11 is bad for MTHFR but it?€™s in Nanna?€™s stack. A bloodtest for MTHFR costs more than 600 euro.

According to what I've read, with a dysfunctional MTHFR gene you have to take the right form of folate, which is methylfolate.

Some people determine if they have MTHFR problems through a genetic test like offered by 23andme. However, this only tests a selected number of SNPs (=locations of the gene), so in theory your copies of the gene could be defective even if the test says they are not. On the other hand, if the test says you have defective MTHFR genes, then you can be sure that you have a problem there.

?€œMethylfolate is a remarkable nutrient yet it can create significant side effects. Those who have MTHFR mutations (especially the C677T MTHFR mutation) learn that methylfolate is critical to take.?€
http://mthfr.net/methylfolate-side-effects/2012/03/01/

It mentions 3 types of response of taking methylfolate and so far I could be either in category first or second response. I will update sooner or later regarding the progress. So be on the look out

[Vandemolen]

I just bought the medicines from the prepack. And Excerdrin instead of those 3 medines. I hope to start wednesday with the stack. And I will take it at least 10 days before I test it.

My question is: can I keep taking other supplements like Zinc. I take Zinc for my prostate problems. Not sure if it helps. And also cefuroxim.

Ok, wish you the best of luck.
Btw, do you happen to know if you have MTHFR? I have not read the whole thread so I don't know if the stack can respond to people with non-mthfr issues.

Not sure about the interactions between the stack and zinc/cefuroxim.

Thanks! I don’t think I have MTHFR. Never heard about it haha. I will google it to see what the symptoms are. Does Nanna have MTHFR? Vitamin B9/11 is bad for MTHFR but it’s in Nanna’s stack. A bloodtest for MTHFR costs more than 600 euro.

No blood test needed.
23andme testing cost 100$ USD then genetic genie for free.
http://geneticgenie.org/

I don’t know if I can trust them. Check this topic about 23andme:

https://poiscenter.com/forums/index.php?topic=1234.msg11453#msg11453

[itsmel]

I just bought the medicines from the prepack. And Excerdrin instead of those 3 medines. I hope to start wednesday with the stack. And I will take it at least 10 days before I test it.

My question is: can I keep taking other supplements like Zinc. I take Zinc for my prostate problems. Not sure if it helps. And also cefuroxim.

Ok, wish you the best of luck.
Btw, do you happen to know if you have MTHFR? I have not read the whole thread so I don't know if the stack can respond to people with non-mthfr issues.

Not sure about the interactions between the stack and zinc/cefuroxim.

Thanks! I don?€™t think I have MTHFR. Never heard about it haha. I will google it to see what the symptoms are. Does Nanna have MTHFR? Vitamin B9/11 is bad for MTHFR but it?€™s in Nanna?€™s stack. A bloodtest for MTHFR costs more than 600 euro.

No blood test needed.
23andme testing cost 100$ USD then genetic genie for free.
http://geneticgenie.org/

I don?€™t know if I can trust them. Check this topic about 23andme:

https://poiscenter.com/forums/index.php?topic=1234.msg11453#msg11453

I see and understand 23andme is not without its controversials but whether the service is legit or not it ultimately lead me to this POIS forum and stumble up nana1 thread which in turn helped me tremendously. You don't have to take the test since if you already purchased the supplements and try that if that works. I'm just letting you know how I discover the information that I have a genetic mutation. To be quite frank, at the time I used the 23andme service I was curious if it would help me cause I'm sure you understand that as a POIS sufferer I was desperate to find answers and would try anything. 100$ is a drop in the bucket compared to all the specialist doctors I went to which netted absolutely no results.

[Vandemolen]

Mel, I understand very good why you turned to 23andme. Because of your positive result with Nana’s stack I will start with it about two days. I had almost all the supplements for a few months. But I was lazy to start taking so many pills. Because I already take some pills. But now it’s sure that helped you and Nanna it’s worth to try it. I will let you the know the result about two weeks. I will ask my PoIS doctor about that MTHFR test.

[itsmel]

Mel, I understand very good why you turned to 23andme. Because of your positive result with Nana’s stack I will start with it about two days. I had almost all the supplements for a few months. But I was lazy to start taking so many pills. Because I already take some pills. But now it’s sure that helped you and Nanna it’s worth to try it. I will let you the know the result about two weeks. I will ask my PoIS doctor about that MTHFR test.

Good luck 

[itsmel]

Just want to report back that I came across my first side effect with the supplement. I would wake up after several hours after going to sleep. Read that B12 can cause insomnia which haven't happen to me yet but instead interruptions. But after some googling, it mentions that intake of potassium might help.

https://forums.phoenixrising.me/index.php?threads/methyl-folate-insomnia.50342/

[Vandemolen]

I started yesterday with Nanna’s stack. Today I woke up with lower back pain. I already have UTI/prostitis. But after going trough this topic I read that Alpha GPC causes lower back pain. So I will start with 1 pill a day for a week. And then go to 2.

[Bombardier]

So I've started using this stack once again, this time making sure I was following a vegan diet. Cutting out animal proteins has indeed helped immensely with my cognitive performance outside of POIS. I've been wondering, however: Is there any indication outside of climaxing that the stack is working for me?

I haven't gotten any additional cognitive benefit since I started the stack, but knowing the answer might give me a great deal of confidence. I'd test this out myself, but I've been very busy at work. Thanks in advance, Nanna.