Author Topic: POIS treatment: theory & supplement stack  (Read 347118 times)

romies

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Re: POIS cure: theory & supplement stack
« Reply #240 on: April 03, 2018, 10:43:03 PM »
  Here is an update on the virus model. Herpes infection chronically elevates COX-2 in the infected cells (even while "dormant"). Arousal/stimulation/intercourse causes the release of neurotransmitters glutamate and norepinephrine.
  This model incorporates the immune response mechanism described here. In this case, chemotaxis means T cell movement to the site of infection, and chemokines (i.e. IL-8) are types of cytokines that tell the T cells where to go.

I am skeptical about the role of glutamate and norepinephrine here.

I have personal experiences with high CNS levels of glutamate (e.g. by eating chinese food loaded with MSG) and norepinephrine (e.g. I was prescribed with Bupropion a while ago, which is a norepinephrine reuptake inhibitor). Neither one, or the combination of the two would trigger POIS-like symptoms.

The glutamate and norepinephrine levels I experienced in those cases were much higher and prolong than a typical orgasm, e.g. hours of insomnia. But I did not suffer from POIS the day after.

So there probably are one or more additional ingredients, such as mast cell activation, and IDO-TDO activation.

1. Mast cell activation syndrome has many similarities to POIS. some details can be found here
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282993/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930370/

And Celebrex has a strong mast-cell stabilizer effect.

The main question is how does an orgasm triggers mast cells? most likely not through NorE or Glu. I don't have an answer, but I am very happy to discuss any hypothesis anyone could provide.

2. Quantum has a long post on IDO-TDO activation: http://poiscenter.com/forums/index.php?topic=2090 I found it very helpful, because 5-HTP was very energizing during my POIS state. Celebrex is a IDO inhibitor. Curcumin/Quercetin are all IDO-TDO inhibitor.

I know probably everyone's POIS is slightly different. But maybe you want to give a try with Celebrex and 5-HTP, individually to see if you respond to them. Then try curcumin and Quercetin as well. (My total annual cost of these supplements/med is around USD $120)

I told my doctor that I have GERD/Heartburn (which is true), and she is happy to prescribe me Celebrex, which has the least gastric side effects among all NSAID. My insurance does not cover it, but it cost about $35 for 60 doses here in the US if you get the generic version.

These were my personal experience. Feel free to point out flaws in my logic above.



b_jim

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Re: POIS cure: theory & supplement stack
« Reply #241 on: April 04, 2018, 07:00:47 AM »
No, because COX-2 is easily blocked by anti-inflammatory drugs and these drugs are not effective against Pois.

Are we 100% sure histamines and No levels are increased during Pois ? I don't thinks so. It seems, but it's not sure.

Anyway, you made a very good job.
« Last Edit: April 04, 2018, 07:03:29 AM by b_jim »
Taurine = Anti-Pois

Muon

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Re: POIS cure: theory & supplement stack
« Reply #242 on: April 04, 2018, 07:34:28 AM »
Nothing is certain until people start coming back with test results. More overlapping test results means narrowing down to the cause of POIS (there should be a common denominator). Bottom line is we need more people going to labs individually and report back to this forum sharing their results (including negative ones) plus we need a doctor setting up research with the NORD grant.
« Last Edit: April 04, 2018, 07:41:58 AM by Muon »

romies

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Re: POIS cure: theory & supplement stack
« Reply #243 on: April 04, 2018, 12:11:00 PM »
No, because COX-2 is easily blocked by anti-inflammatory drugs and these drugs are not effective against Pois.

The COX-2 inside your brain is not easily reached by most anti-inflammatory drugs, due to the blood-brain barrier. Celebrex is one exception

Are we 100% sure histamines and No levels are increased during Pois ? I don't thinks so. It seems, but it's not sure.

I completely agree that we need to further develop these hypotheses into something testable, by blood works and other tests.

romies

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Re: POIS cure: theory & supplement stack
« Reply #244 on: April 04, 2018, 12:14:59 PM »
Nothing is certain until people start coming back with test results. More overlapping test results means narrowing down to the cause of POIS (there should be a common denominator). Bottom line is we need more people going to labs individually and report back to this forum sharing their results (including negative ones) plus we need a doctor setting up research with the NORD grant.

Non-invasive lab testing involving central neural system is very hard. The brain-blood barrier makes most biochemical markers in the blood meaningless. That's why there is no blood test for depression etc, and scientists still do not have direct evidence on how exactly SSRI works.

I am afraid at this stage, most tests will be indirect and involving changing regiments, a lot of time and efforts involved.

nanna1

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Re: POIS cure: theory & supplement stack
« Reply #245 on: April 05, 2018, 01:03:42 PM »
Article from Forbes Magazine: "Surprise! Arthritis Drug Celebrex Shown As Safe As Ibuprofen And Naproxen"

The title of this article is very modest. Celecoxib (Celebrex) was shown to be significantly safer than Ibuprofen and Naproxen in every tested category of risk.

POIS clusters: 1,3,4,5,7
POIS criteria: 1,2,3,4,5
2 stacks that give me complete relief of POIS symptoms are listed here: POIS cure: theory & supplement stack
Find medical test: https://www.findlabtest.com/

romies

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Re: POIS cure: theory & supplement stack
« Reply #246 on: April 05, 2018, 01:58:53 PM »
Article from Forbes Magazine: "Surprise! Arthritis Drug Celebrex Shown As Safe As Ibuprofen And Naproxen"

The title of this article is very modest. Celecoxib (Celebrex) was shown to be significantly safer than Ibuprofen and Naproxen in every tested category of risk.

Very interesting study indeed. Thanks for sharing it. I read the original study at: http://www.nejm.org/doi/full/10.1056/NEJMoa1611593

It compares an averaged daily dosage of 209mg Celecoxib (I usually need only 1x 200mg Celecoxib capsule per O) to a daily dosage of 852mg Naproxen or 2045mg Ibuprofen. The dosages of the latter two are fairly large but not uncommon for people with arthritis.

This study should make people feeling quite a bit easier for occasionally taking an capsule of Celecoxib for an O.

nanna1

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Re: POIS cure: theory & supplement stack
« Reply #247 on: April 19, 2018, 12:38:55 AM »

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011108/

A major component of the inflammatory pathway is called the arachidonic acid pathway because arachidonic acid is immediately released from traumatized cellular membranes. Membrane-based arachidonic acid is transformed into prostaglandins and thromboxanes partly through the enzymatic action of cyclooxygenase (COX)[34,57]. There are two types of COX enzymes, COX-1 and COX-2. Both the enzymes act similarly, but selective inhibition (as accomplished by selective COX-2 inhibiting NSAIDs) can make a difference in terms of side effects.

Thanks Hopeoneday for sharing this article ("Natural anti-inflammatory agents for pain relief" above). It has a lot of practical information!  :)
POIS clusters: 1,3,4,5,7
POIS criteria: 1,2,3,4,5
2 stacks that give me complete relief of POIS symptoms are listed here: POIS cure: theory & supplement stack
Find medical test: https://www.findlabtest.com/

Quantum

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Re: POIS cure: theory & supplement stack
« Reply #248 on: April 21, 2018, 07:34:38 PM »
Hi Nanna, and everyone,

I stumbled upon an interesting wikipedia article about fatty acids and inflammation, that can help deepen, for interested members, the understanding of Nanna's POIS cascade hypothesis, in particular the part about AA and phospholipase, and also why EPA/omega-3 are useful in preventing inflammation:

https://en.wikipedia.org/wiki/Essential_fatty_acid_interactions

There is a section detailing the 3 mechanisms by which omega-3 are blocking AA inflammatory response:  https://en.wikipedia.org/wiki/Essential_fatty_acid_interactions#Mechanisms_of_%CF%89-3_eicosanoid_action

There is also a special section for the AA cascade in the brain: https://en.wikipedia.org/wiki/Essential_fatty_acid_interactions#The_arachidonic_acid_cascade_in_the_central_nervous_system_(CNS)

I hope this will be useful for a better understanding of the role of AA in inflammation, and the usefullness of omega-3 fatty acids.  We may still wonder exactly what chain of event triggers POIS, but however, we can work on blocking the AA cascade once triggered ( and it really seems to be at play in many POIS cases), even if we do not exactly know how it comes to be triggered.  At least, this brings relief, at least in part of the POIS cases.


BTW, Nanna, I am currently working on a complementary hypothesis ( another neurotransmitter-related branch) about how ejaculation could come to trigger an inflammatory response in the brain.... more on that later, I have to test a bit on myself before.

And, I would like to know what software you use to create your nice diagrams, they are very clear and clean, with nice colors :)


You are 100% responsible for what you do with anything I post on this forum and of any consequence it could have for you.  Forum rule: ""Do not use POISCenter as a substitute for, or to give, medical advice" Read the remaining part at http://poiscenter.com/forums/index.php?topic=1.msg10259#msg10259

nanna1

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Re: POIS cure: theory & supplement stack
« Reply #249 on: April 22, 2018, 06:16:07 PM »
Good link on AA, Quantum! I like that they explain the different prostaglandin receptors (EP1, EP2,..., EP5) separately in the Complexity of Pathways section.

I use Microsoft PowerPoint for the diagrams. They are mostly textboxes and shapes (and arrows). You can set the properties of the shapes (example tutorial).  :)
POIS clusters: 1,3,4,5,7
POIS criteria: 1,2,3,4,5
2 stacks that give me complete relief of POIS symptoms are listed here: POIS cure: theory & supplement stack
Find medical test: https://www.findlabtest.com/

Quantum

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Re: POIS cure: theory & supplement stack
« Reply #250 on: April 22, 2018, 07:19:47 PM »
Hi Nanna,

this particular section you are referring to, shows how complex the immune system is !   :)


Thanks for the info about the diagrams !  When I was in university, there was no Power Point, and minimal computer usage....  this was a while ago...hehe....  our diagrams were drawn freehand, or I remember using a really old version of MacDraw, on my now antique Macintosh Plus, but everything had to be actually drawn, there was no pre-formed arrows, or else.... and no colors, of course, it was in black and white !
« Last Edit: April 22, 2018, 07:53:07 PM by Quantum »
You are 100% responsible for what you do with anything I post on this forum and of any consequence it could have for you.  Forum rule: ""Do not use POISCenter as a substitute for, or to give, medical advice" Read the remaining part at http://poiscenter.com/forums/index.php?topic=1.msg10259#msg10259

demografx

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Re: POIS cure: theory & supplement stack
« Reply #251 on: April 22, 2018, 07:52:22 PM »
Nanna, great looking diagrams!
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

Nas

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Re: POIS cure: theory & supplement stack
« Reply #252 on: April 25, 2018, 02:21:54 PM »
Nothing is certain until people start coming back with test results. More overlapping test results means narrowing down to the cause of POIS (there should be a common denominator). Bottom line is we need more people going to labs individually and report back to this forum sharing their results (including negative ones) plus we need a doctor setting up research with the NORD grant.

Hey Moun, so I reflected on what you said, and I realized that I once actually did an EGG scan on my brain:

https://drive.google.com/open?id=0B1uR2kQKGjb5cmhZYnpZaDZtaE0.

I told the Doctor that I had inflammation in my brain after orgasm and he tested me based on that. When the scan was finished he didn't confirm that I had inflammation and he dismissed what I have as depression.

I wish if someone can read the scan properly and see if there is a sign of inflammation, because that would help a lot if I can use this as evidence that what I suffer if physiological rather than psychological.

Michael218

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Re: POIS cure: theory & supplement stack
« Reply #253 on: April 28, 2018, 12:57:12 AM »
I agree totally with Romies.

The first step this forum should establish in my view, is listing 1 or several very specific tests that each POIS sufferer can get done. They would then upload these test results to this forum.

There are seemingly enough experts here that would be able to conclude further based on our test results.

Secondly, people should upload whether they have  other conditions, and they should also be sent a table to fill out which shows exactly what they eat each day. This will enable the more technical experts on this forum with PHDs and relevant degrees to apply their knowledge to these statistics...

People should also include their type of POIS, what helps or triggers symptoms etc.

The research doesn't seem to be going anywhere, perhaps we can use the funds available to create a dynamic form which we can all use to upload and contribute relevant data, which we can later use to submit to doctors for analysis...

I would certainly be a participant in this.

demografx

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Re: POIS cure: theory & supplement stack
« Reply #254 on: April 28, 2018, 01:52:03 AM »
Thanks, Michael!

Regarding your question of diverting some or all of our funding to create a dynamic form: unfortunately NORD has no refund mechanism in place for our $31,000 POIS Research Grant.

NORD also decides - not us - who will finally be chosen to conduct this forum’s POIS research.

NORD is a very solid, reputable organization.
www.rarediseases.org

Michael, maybe we can all work together with the chosen research team and your very good ideas about member identification and data capture.

« Last Edit: April 28, 2018, 02:30:47 AM by demografx »
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

Muon

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Re: POIS cure: theory & supplement stack
« Reply #255 on: April 28, 2018, 08:27:20 AM »
Nothing is certain until people start coming back with test results. More overlapping test results means narrowing down to the cause of POIS (there should be a common denominator). Bottom line is we need more people going to labs individually and report back to this forum sharing their results (including negative ones) plus we need a doctor setting up research with the NORD grant.

Hey Moun, so I reflected on what you said, and I realized that I once actually did an EGG scan on my brain:

https://drive.google.com/open?id=0B1uR2kQKGjb5cmhZYnpZaDZtaE0.

I told the Doctor that I had inflammation in my brain after orgasm and he tested me based on that. When the scan was finished he didn't confirm that I had inflammation and he dismissed what I have as depression.

I wish if someone can read the scan properly and see if there is a sign of inflammation, because that would help a lot if I can use this as evidence that what I suffer if physiological rather than psychological.

The above data from Nas and this thread---> http://poiscenter.com/forums/index.php?topic=2680.msg23744
should both be placed in a new category (data only category) separated by their own thread.

Hopeoneday

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Re: POIS cure: theory & supplement stack
« Reply #256 on: April 28, 2018, 01:06:19 PM »
Well i tought obout this lately to open treed "post here all yours test results that we can compare" , that could help us a lot. But i didnt because asking people to post there private lab results seem to me not etic.
But we have no choice- isnt we?
Dr-pois.

Nas

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Re: POIS cure: theory & supplement stack
« Reply #257 on: April 28, 2018, 06:19:15 PM »
Nothing is certain until people start coming back with test results. More overlapping test results means narrowing down to the cause of POIS (there should be a common denominator). Bottom line is we need more people going to labs individually and report back to this forum sharing their results (including negative ones) plus we need a doctor setting up research with the NORD grant.

Hey Moun, so I reflected on what you said, and I realized that I once actually did an EGG scan on my brain:

https://drive.google.com/open?id=0B1uR2kQKGjb5cmhZYnpZaDZtaE0.

I told the Doctor that I had inflammation in my brain after orgasm and he tested me based on that. When the scan was finished he didn't confirm that I had inflammation and he dismissed what I have as depression.

I wish if someone can read the scan properly and see if there is a sign of inflammation, because that would help a lot if I can use this as evidence that what I suffer if physiological rather than psychological.

The above data from Nas and this thread---> http://poiscenter.com/forums/index.php?topic=2680.msg23744
should both be placed in a new category (data only category) separated by their own thread.

Yes and I really wish if someone can analyse it for signs of inflammation. It would do me great help if it confirmed that I have inflammation.

melt

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Re: POIS cure: theory & supplement stack
« Reply #258 on: April 30, 2018, 08:49:19 AM »
Wow Nanna1, very interesting and detailed research there. I?ve only quickly skimmed but I will take a good look once I have time.
I am pharmacist and dentist. I don?t work as a pharmacist anymore though.
I?ve had POIS since 2012, I?m not sure how it all started but my theory is that it could have been a combination of roaccutane treatment for acne, excessive orgasms (twice a day), and coffee.
These are just my theories and I haven?t taken the time to delve further into it but your research has got me excited. Please feel free to pick apart and/ or prove these theories.
1.   Roaccutane is a modified Vitamin A analogue, so it basically replaced my natural vitamin A for this synthetic version which may have changed the way my body responds to stress and orgasms.
2.   Excessive orgasms sensitises the body to a ?threat? and makes it respond defensively to fight off this threat and started the change towards POIS
3.   Daily coffee consumption, coffee is a diuretic which would cause your body to flush out vital nutrients which when not replaced would place the body under significant stress, the body?s response to stress would be pro inflammatory  catabolic in nature

Like everyone here, I didn?t know what was happening with my body, eventually I saw a sexual health doctor who diagnosed me with POIS, I had some investigations done and all the blood work was normal. I saw an immunologist who said my symptoms were not consistent with a type 1 allergic response meaning I wasn?t having anaphylaxis/ ALLERGY to my semen.
He thought that my symptoms were a manifestation of neurologic inflammation.
So the inflammation is triggered along nerve pathways.
Ejaculation and orgasm is controlled by the sympathetic nervous system (SNS)
The SNS practically connects to the entire body which explains why the POIS symptoms are far reaching and affects every single part of the body from your head to your toes.
So how to stop the inflammation?
1.   Remove the cause ? stop ejaculating, which is practically impossible
2.   Use anti-inflammatory methods ? which is what I do but I haven?t been able to cure POIS yet.
My anti-inflammatory methods.
My POIS symptoms have become milder and I can recover up to 90% within 1 day if I complete all the steps.
1.   Chiropractic adjustment of back and neck
2.   Deep tissue massage full body
3.   Gym session whole body rehab with machines
4.   Epsom salt bath
5.   Lumosity brain training
6.   Take supplements and medicine
7.   Sinus rinse
8.   Peppermint tea, Pu Er Tea , Oolong Tea
9.   Pelvic floor strengthening
10.   Vocal workout
Chiropractic adjustment
-   The neck is the information highway that connects your brain to the rest of your body
-   POIS results in inflammation in the muscles around the neck
-   A stiff neck results in poor information transmission between the head and the body
-   Headaches, sore shoulders, brain fog, muscle pain and weakness, irritability and mood disturbances are related to the stiff neck
-   All muscles connect to bone and allow movement of the particular limb
-   Various neck muscles connect to the spine. Inflammation in the muscle results in tightness of the muscle and swelling which pulls the spine towards the contracted muscle and out of its proper alignment.
-   Releasing the muscle through soft tissue work (targeted massage) and spinal adjustments removes the tension in the neck and relieves the associated symptoms.
-   You should book a chiropractic adjustment for the same day you plan to ejaculate
-   Absolutely vital for recovery
Deep tissue full body massage
-   POIS is generalised inflammation of the muscles and other tissues
-   The muscles become swollen and painful
-   Swollen, painful muscles don?t operate properly as non-inflammed muscles
-   Thus the muscles don?t support the joints adequately and you get joint pain
-   You need to remove the inflammatory fluid from the muscles by massaging it out
-   A deep tissue massages targets the sore spots on the muscles and relieves the tension and pain.
-   It is a painful massage but you need to do it
Gym session
-   Since the muscles are out of whack, you need to rehab the muscles with a good gym session
-   Don?t push too hard since the muscles don?t function to their full capacity and you risk getting injured
-   I use the machines at the gym since they?re easy and safe to use and isolate various muscle groups
-   Start with the biggest muscle group, the legs, then work your way to the core, arms, back
-   Jump on the bike, do cardio, get a good sweat out of the workout to also cleanse the muscles of inflammatory fluid
-   Do push ups, squats, make sure to sweat a lot
-   Go for a swim ? water provides a great environment for muscle rehab
-   Aim is to get each and every muscle moving in its normal range of motion so that it can support everyday tasks and movement
-   Do sets of 10 starting at a light weight and increase progressively
-   Wear compression gear to improve circulation and remove inflammatory fluid from the muscles faster
-   I wear Skins calf compression on both sides
-   I wear elastic knee supports on both sides and also elbow supports now that I have tennis elbow

Epsom salt bath/ swim in the ocean
-   Via the process of osmosis, inflammatory fluid can be drawn out of the muscles towards the outside of the body as you sit in a salt bath
-   I use about 1kg of Epsom salt in a 150 L bath tub using warm water and submerging myself for about 30mins
-   It can make you quite dehydrated so make sure to drink plenty of water and replace electrolytes
-   Drink hydralyte or Gatorade/powerade ? make sure to rinse out with water since these drinks are acidic and will cause acid erosion of the teeth over time. Can also use a fluoride mouth wash after drinking your electrolytes
-   You need to drink electrolytes because the electrolytes in your blood have moved into your muscles so it is low in the blood and needs to be replaced
-   If you don?t replace electrolytes, then you don?t get maximal extraction of the inflammatory fluid in the muscles
-   The body self regulates and will try to retain fluid when the body is dehydrated so you need to treat the dehydration with electrolytes
-   Go soak in the ocean achieves a similar result and is probably better since you can move freely whilst floating in the water

Lumosity brain training
-   Brain fog is inflammation in the brain
-   Principle is to use exercise once again to clear the inflammatory fluid
-   Push ups in plank position is great for pushing fresh blood into the head and clearing away toxins and metabolites to speed up recovery
-   Lumosity brain training is fantastic in that it provides categorised games that target a different attribute. The games focus on speed, memory, attention, flexibility, problem solving
-   This game is worth subscribing for the lifetime which ends up being cheaper in the long run
-   Once you?ve mastered the games, it can get a bit boring so you can find other brain training games to give your brain a workout and clear the brain fog
-   The games are quick and easy to play taking about a minute per game
-   Reading gets the brain ticking as well
-   Information processing, problem solving, anything that gets the brain thinking will help

Supplements
These supplements are mostly anti-oxidants and may be in higher demand when the body is stressed during POIS. I prefer to take the maximal dose according to the packaging. If unsure check with your health care professional.
-   Vitamin C 1000mg daily
o    Vitamin C is a cofactor in collagen synthesis, collagen is found in connective tissue and essentially all over the body
o   Inflammation of the muscles causes damage to the muscles and hence you need to repair it. Vitamin c helps with the repair process
-   Magnesium 150mg daily
o   Magnesium is required for muscle contraction, low magnesium leads to muscle spasms
-   Mega B complex daily
o   B vitamins help regulate stress and improve energy production in the body, so it helps to counter the stress of POIS on the body
-   coQ10 600mg once or twice daily
o   CoQ10 is a cofactor in ATP synthesis which is an energy molecule. It helps with energy production in the body and is supposedly depleted with age
-   N-acetyl cysteine (NAC) 600mg daily
o   NAC is an antioxidant which supports liver function, the liver metabolises toxins and removes it from the body
-   Probiotics30 billion CFU
o   Required for gut health. Gut inflammation arises from POIS and hence the intestinal barrier to infection is weakened and you find yourself getting sick easily. Good and bad bugs reside in the gut. The gut acts as a barrier keeping these bugs out but when it is weakened with inflammation, some bad bugs get in and make you sick.
o   Probiotics increase the number of good bacteria
-   Curcumin 500mg
o   Anti-inflammatory take before1 hr ejactulation
-   Vitamin D3 5000iu 1 capsule weekly
o   A lot of people are low in Vitamin D from lack of sun exposure
Medicine
Pseudoephedrine 30mg ? helps clear the sinus and brain fog
Phenergan 25mg ? antihistamine counters the inflammation and reduces the swelling in the muscles ? take 1 at night
Sertraline 100mg ? SSRI ? great for clearing the brain fog, great for premature ejaculation, take 50mg in the morning and 50mg half an hr before sex. Get a prescription from your doctor
Bisolvon 100mg  - for phlegm in the chest which is basically inflammation in the chest lining like in asthma
Ventolin 100ug ? to open the lungs and improve clearance of the phlegm and make it easier to breathe ? take 2-3 puffs as needed
Telfast 180mg ? antihistamine for swelling and sinuses, take 1 in the morning
Nurofen 200mg ? anti-inflammatory NSAID ? take 1-2 30mins before sex and afterwards as needed
Sinus rinse
-   Get a flo sinus rinse, fill with water, add 1-2 sachets of the salt into warm water and use after POIS to counter the sinus inflammation
-   This is a must. It is a bit daunting to do initially, stand over a sink, breath in and squeeze it into your nostril as you breath out and cough at the same time
-   Takes some coordination  but the water should go in from your nose and out the back of your mouth
-   Blow your nose,
-   Bend over tilt your head to the side so one eye is on top of the other and blow your nose then turn to the other side and blow your nose
Peppermint tea
-   Is effective in irritable bowel syndrome which is inflamed bowels!
-   Great for settling the bowels and reducing inflammation in the bowels and hence prevent break down of the gut lining and reducing the risk of infection and getting sick with the flu
-   Make the tea 2 tea bags in a small volume of water and take it like a shot
Pu er tea
-   Great for digestion problems, it seems to get the bowels moving
Oolong tea
-   Anti-stress tea ? very calming

Pelvic floor strengthening
-   I believe that weak pelvic floor is a driver for premature ejaculation and I suspect that spasms in the pelvic floor are a trigger for POIS
-   Strengthening the pelvic floor will reduce premature ejaculation and it seems to lessen the POIS response
-   Squeeze the muscle that hold in the piss, count to 100 and squeeze for each number, or count to 100 and squeeze from 1-100, repeat 5 times
Vocal workout
-   I find I get a bit of a stutter once POIS hits
-   This would be inflammation of the tongue and facial muscles
-   Exercising the voice will get these muscles moving
-   Count out loud 1-100 and squeeze the pelvic floor at the same time
-   Count the alphabet
-   Count the alphabet but call out the sounds ba ca da fa ga etc
o   Then be ce de fe
o   Then bi ci di fi
o   Then bo co do fo
o   Then bu cu du fu
-   Repeat 5 times
-   I usually do this in the car while driving to work so I don?t look ridiculous

Try it! It definitely works and is based on sound scientific principles.
If you do all this on the day of POIS you can recover quite quickly but I still find there is like a residual 10% of POIS that takes more time to shift




Hopeoneday

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Re: POIS cure: theory & supplement stack
« Reply #259 on: April 30, 2018, 01:29:27 PM »
Auuufffffffffffff melt whot did you yust wrote here ;D
Enything else to take? ;D
« Last Edit: April 30, 2018, 01:37:54 PM by Hopeoneday »
Dr-pois.