Author Topic: Modafinil reduces symptoms  (Read 336 times)

Luca

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Modafinil reduces symptoms
« on: December 12, 2021, 02:01:35 PM »
After orgasm, I get anxiety, extremly disturbing intrusive thoughts, fatigue, headaches, binge eating, low motivation and weight gain. 50 mg Modafinil reduced fatigue and anxiety, lowered appetite, incresead motivation and even reduced a lot of the intrusive non stop thoughts.I will up the dose to 100 mg hoping to get an even better relief.

POISed2cure

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Re: Modafinil reduces symptoms
« Reply #1 on: April 27, 2022, 06:32:00 AM »
And? Was there any update?

eccentricbipois

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Re: Modafinil reduces symptoms
« Reply #2 on: April 27, 2022, 04:43:35 PM »
I've been prescribed armodafinil 200mg daily (variant of modafinil) to address general anxiety, focus and attention issues as well as combat the side effects of a SSRI medication I also take and I've noticed it provide some relief as well. The nurse practitioner that originally prescribed this to me was aware of my POIS though and proposed this medication as a way to help normalize the dopamine spike and withdrawal since it's a dopamine reuptake inhibitor... that was the idea anyway, I'm honestly not savvy to what exactly is happening here and I get the feeling that the "experts" I've talked to are not so savvy either  :-X
Best idea so far (completely prevents POIS symptoms for me): Take 15 mg Loratadine quick-dissolve tabs via sublingual administration most effectively 30 min prior to O, otherwise immediately after.

POISed2cure

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Re: Modafinil reduces symptoms
« Reply #3 on: May 17, 2022, 11:49:44 AM »
I have terrible sleep and often wake up so exhausted that I can barely stand up. I took Modafinil for the first time this week after waking up exhausted (the drug is primarily used for people with sleep disorders, narcolepsy, etc, so it made sense) and it enabled me to function at about 80+% the entire day. I couldn't believe it. Today was my 2nd day and it worked again all day. Long half-life drug. I just hope it's not placebo or tolerance doesn't build up. An amazing breakthrough if it continues, and I got the idea from this forum!
However, I had an O and went straight into POIS after trialing fenugreek, garlic and berries (which did nothing for me). So I decided to see the effect of Modafinil on POIS symptoms and it made it much worse. I was surprised and thought it may actually help. Gave me terrible anxiety. I could barely go outside because of it so I took the usual propranolol dose a few hours after and symptoms reduced.

So for me, a NO for modafinil for POIS, but excellent for lack of deep sleep (so far).
« Last Edit: May 18, 2022, 08:33:51 AM by POISed2cure »