I do believe Adrenal gland is the master root cause for POIS (or you can call it chronic stress). However adrenal gland/HPA axis is also fuzzy. Adrenal glands first casualty is Thyroid gland. Thyroid gland the master regulator for metabolism is producing a cascade of events (various metabolic path impairments), simple e.g. like when you eat protein, allergans are getting produced, autophagy (garbage cleaning) is not happening, causing auto immunity issues. All these dysfunctions are producing inflammation causing POIS.
Just saying ... you could very well nick and pick inflammation - an "effect" of a cause by helping our big Pharma friends and helping them create 1000's of meds and 1000's of diseases - the "effects" and not the "cause", or you can thoroughly understand the one thyroid and nip the problem at its origin. And while I do think adrenals or HPA axis is the actual real cause and wish there was a supplement, but adrenal overdrive is caused by your experiences/events that have happened. Yoga will help, CBT's will help but question is how much. The 2nd point of intervention is Thyroid, and really the first effective point of intervention for a molecule drug is indeed Thyroid. Docs are not treating nor diagnosing thyroid right because of the medical framework constraints they have been trained to follow, they have boxed themselves in it, it is time-consuming but treatment is simple. TSH, T4, T3 balancing could be complex or could be very easy once you understand it. Thats my area of research at present. (I'm not into medical sciences guys so its challenging for me, but I'm very very thorough, I wish others with expertise would be brave enough to confront the current state of medical sciences and and look at thyroid - the root problem, with an open mind).
Did someone took a scan of the...pituitary?
Normal.
Ok. Would be great if someone did a scan for the adrenal glands.