Have you taken Progesterone for POIS?

[FloppyBanana]

Some Doctors are willing to prescribe Progesterone to males. Makers of the drug have confirmed that it is safe for men to take. However there is no robust medical research been done in this area. Please refer to the observational medical paper written by Dr Dexter (UK) "Benign coital headache relieved by partner?s pregnancies with implications for future treatment" for further reading.

[FloppyBanana]

I need to take seven 5 mg tablets over 5 days to reduce symptoms to the maximum. This reduces symptoms more than half although the cognitive aspects are present but much lighter. Physical (outside the mind) can be illuminated through this regime for me.

I don't think it necessary indicates a hormonal cause. My hormones (prolactin, oxytocin, testosterone (in 3 different ways), progesterone and more ) were tested and they were all within the normal expected ranges. I think they must of tested for oestrogen but I can't remember. When I am told that all my hormone levels are fine then I can't help but think it must be my immune system kicking off. I guessing though.

Progesterone I believe is linked to the fact that pregnant women sometimes loose their allergies. This could be because of the very large amounts of progesterone women produce. In most cases the allergy comes back after birth and sometimes much stronger. In some rare cases an allergy can go from having been pregnant.

Its worth reminding that taking Progesterone reduces testosterone in the short term (about 7 days with above amounts considered).

I have been taking Mucuna Pruriens after 7 days of ejac to give my testosterone a push as it stimulates the production of the hormone. I can really notice it when I have a big tables spoon of the powder in hot water. After 30 mins I feel like doing something physical. Body builders use it. I'm not sure how safest is though. I would expect relatively safe though.

FB

[FloppyBanana]

I think I made an error in my last post. Actually Mucuna Pruriens increases dopamine not testosterone.
FB

[Prancer]

I think I made an error in my last post. Actually Mucuna Pruriens increases dopamine not testosterone.
FB

I think it does both (at least that's what I read), anyway I ordered some and am going to give it a try.

[FloppyBanana]

Prancer,
I thought I read somewhere that it increased testosterone but I wasn't sure. So thanks for clarifying. It would be good to quote the source.

Hi All,

I would like to share a recent breakthrough which occurred this week. I had sex twice over two days and I feel virtually POIS symptom free. I consider myself to be someone that has severe POIS with most symptoms (80%) without medication last a week then it tails out for the remaining 20% the week after. So two weeks in total. Being POIS free has never happen to me as much as now. Previously to have sex two days in a row would be a disaster. But I have been relaxed and confident in meetings at work.

So how come I feel so good? I have to admit the week has yet to finish so there may be a delayed response in the comings days but I feel positive. That is unusual for someone who has had POIS for more than 24 years. I am all too aware of set backs.

I have been taking Neem oil for 2 weeks now. I take two oil capsules a day each one being 0.25MG. Neem apparently has shown to cause reversable infertility in studies. Apparently a study was done in the Indian army and after 6 weeks of taking Neem oil (amounts unknown) they were able to be totally infertile and after 6 weeks of stopping taking it they were fertile again. I think Neem destroys the tale of sperms so they can't go anywhere. It is known to boost immune responses and act as an antiseptic. NOTE, it is advised for "young" people not to take it. Not sure what the age ranges are.

So I had two Os, one this sunday without taking Niacin and one Monday night. The second time I took 200mg of Niacin but didn't flush, shot my gun then had a massive flush afterwards. I think Niacin was able to have a very positive effect even though I O'd before flush.

For me - I believe - the most powerful symptom reliever is Progesterone. I have changed the way I take it with remarkably improved results. I take one tablet (5mg) before orgasm and one after. I don't have sex before 7pm because the progesterone can make me feel cold for some reason if I take it before this time. My first routine involved taking two on day one then one tablet for next 5 days. The step change for me has been to take 2 tablets on the second day before I go to bed. For me at least the first two days of POIS seem to be critical. I have tried this regime 3 times over two months now so I feel I am looking at this with a level head.

I would estimate the order of efficacy for me is:
1) Prosterone (50%)
2) Niacin (30%)
3) Neem (unknown)
4) Mucuna Pruriens (it has strong effect but I can yet work out if it relieves POIS. I suspect it may increase libido considerably) I ordered a bucket of the stuff for long terms testing...

I think with Neem I need to take it for a couple of months solid before I can if it really say it makes a difference. Is it just coincidence I am virtually POIS free now (at this point in time??!)

This week I thought if only Dr Dexters paper on POIS (post coital headache) was released ten years ago my life would be a whole lot different. This shows me that the years of emotional pressure have started to lift off. Its all positive (in a sense). Perhaps this indicates a POIS type. i.e. negative semen skin prick test, Niacin works, progesterone works.

I hope this post is of use to someone out there and thanks to the creators of this forum.
FB

[poiseidon]

this is a great news for you !! i hope it  ll continue to work.

[Daveman]

Prancer,
I thought I read somewhere that it increased testosterone but I wasn't sure. So thanks for clarifying. It would be good to quote the source.

Hi All,

I would like to share a recent breakthrough which occurred this week. I had sex twice over two days and I feel virtually POIS symptom free. I consider myself to be someone that has severe POIS with most symptoms (80%) without medication last a week then it tails out for the remaining 20% the week after. So two weeks in total. Being POIS free has never happen to me as much as now. Previously to have sex two days in a row would be a disaster. But I have been relaxed and confident in meetings at work.

So how come I feel so good? I have to admit the week has yet to finish so there may be a delayed response in the comings days but I feel positive. That is unusual for someone who has had POIS for more than 24 years. I am all too aware of set backs.

I have been taking Neem oil for 2 weeks now. I take two oil capsules a day each one being 0.25MG. Neem apparently has shown to cause reversable infertility in studies. Apparently a study was done in the Indian army and after 6 weeks of taking Neem oil (amounts unknown) they were able to be totally infertile and after 6 weeks of stopping taking it they were fertile again. I think Neem destroys the tale of sperms so they can't go anywhere. It is known to boost immune responses and act as an antiseptic. NOTE, it is advised for "young" people not to take it. Not sure what the age ranges are.

So I had two Os, one this sunday without taking Niacin and one Monday night. The second time I took 200mg of Niacin but didn't flush, shot my gun then had a massive flush afterwards. I think Niacin was able to have a very positive effect even though I O'd before flush.

For me - I believe - the most powerful symptom reliever is Progesterone. I have changed the way I take it with remarkably improved results. I take one tablet (5mg) before orgasm and one after. I don't have sex before 7pm because the progesterone can make me feel cold for some reason if I take it before this time. My first routine involved taking two on day one then one tablet for next 5 days. The step change for me has been to take 2 tablets on the second day before I go to bed. For me at least the first two days of POIS seem to be critical. I have tried this regime 3 times over two months now so I feel I am looking at this with a level head.

I would estimate the order of efficacy for me is:
1) Prosterone (50%)
2) Niacin (30%)
3) Neem (unknown)
4) Mucuna Pruriens (it has strong effect but I can yet work out if it relieves POIS. I suspect it may increase libido considerably) I ordered a bucket of the stuff for long terms testing...

I think with Neem I need to take it for a couple of months solid before I can if it really say it makes a difference. Is it just coincidence I am virtually POIS free now (at this point in time??!)

This week I thought if only Dr Dexters paper on POIS (post coital headache) was released ten years ago my life would be a whole lot different. This shows me that the years of emotional pressure have started to lift off. Its all positive (in a sense). Perhaps this indicates a POIS type. i.e. negative semen skin prick test, Niacin works, progesterone works.

I hope this post is of use to someone out there and thanks to the creators of this forum.
FB

Cool.

So you are combining the Neem with what you were doing before, but only changing the niacin a little?

You mention the neem and then talk about the other stuff. Could you say exactly what you are taking finally, the final recipe, just to clarify. Thanks


We had talked about male contraceptives at one time. That was when we thought it was "allergy" but it could still work for "auto-immune".

[demografx]

I took progesterone and quit after 4 days, bad side effects.

[poiseidon]

I would like to share a recent breakthrough which occurred this week. I had sex twice over two days and I feel virtually POIS symptom free. I consider myself to be someone that has severe POIS with most symptoms (80%) without medication last a week then it tails out for the remaining 20% the week after. So two weeks in total. Being POIS free has never happen to me as much as now. Previously to have sex two days in a row would be a disaster. But I have been relaxed and confident in meetings at work.

Hey FB, how's going with Neem?

[FloppyBanana]

Hi poiseidon and Daveman,

I have only just seen your posts. It seems that even though I check the "show unread posts since last visit" link regularly I still miss posts.

I ran out of neem and slipped up on my regime of taking it so its still to difficult to gauge at the moment. Wife wants wants baby so may have to stop taking it as it is a form of contraception.

Niacin - As I reported below I had a very strong flush which I think helped. I took the same amount recently and only had a medium flush and feel slightly more POISy. Although I think that may down to having sex twice in the morning. It seemed a good idea at the time but I get the worst POIS from morning sex. If I have sex say 7pm before dinner, niacin flush on empty stomach, 10mg progesterone, big meal, relax for a couple of hours hours I get a good nights sleep. I seem to sleep for 7 hours or less with this regime. With no medication I would sleep for ten hours and wake up feeling like a caveman that had just been clubbed over the head.

I must mention that even though I had such a positive experience (below post) I had to take progesterone for 12 days (as opposed to normal 5 days). What I learnt from this was that 2 O's means twice as much progesterone medication. When I wrote the below post I thought I had successfully slipped in two O's for the price of one, so to speak, but this was not the case. To my surprise when I tried to stop taking progesterone I got headaches. At this stage I am not clear whether the headache is from mild POIS or some sort of progesterone withdrawal. My bet is on mild POIS as I had tight muscles in the neck which would crack if I gave them a stretch. If this is true then the POIS generation cycle is fully in process for 12 days (after 2 O's). The first two days of taking a double dose of progesterone is a critical period but at the same time it seems my POIS "producer" keeps on ticking for a while after.

Going forward I need to stick to one O very two weeks to be able to monitor this better. Temptation often interferes though. I also have feeling that my body is adjusting to the medication in a positive way. I hope it is OK and it does not cause any problems later down the line. It's a risk I have to bear responsibility for. I need to have a month off Progesterone in Jan to see how my hormones balance back to normal. The main obvious factor of Progesterone being the effect on testosterone. Progesterone reduces testosterone in short term but long term we don't know what what happens. Sperm test will be done in Jan on and off progesterone to look for any possible effects.
FloppyB

[Daveman]

@FB

Would have been interesting to do a sperm count before the "withdrawl" from prosgeterone. Don't know if it's too late.

A sort of confirmation that prog. does reduce sperm, and by how much.

[FloppyBanana]

Noted. I will discuss with Dr Dexter how best to catch this (not literally). I expect it will be take progesterone for 3 days even when have no POIS then provide sample.

[FloppyBanana]

Hi All,

I met with Dr Dexter today and he prescribed Progesterone as usual to me. He mentioned that Vitaman D is a protagonist to Progesterone, meaning it can increase the effect of progesterone in the body. So I got myself a tub of Vit D and will start taking it when I take the progesterone. I will share any results. I had a quick look on the net to see if there were any info about vit D and progesterone and I found this which is not related to POIS. The article is heavy on the medical terminology. It mentions both vit d and Progesterone are Neuroprotective Agents.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025702/

FloppyB

[Colm]

Hi FB,

Thanks for posting your experiences with Progesterone and your Dr's advice on Vitamin D in parallel. I am interested to hear more about your further experiences.

[demografx]

Progesterone did not work for me.

Testosterone works perfectly (for me).

!

[Colm]

Hi Demo,

With testosterone (and your positive experiences), it is tempting to think about a trial of this, as it appears from some searches, that middle aged blokes can benefit cognitively and my own child rearing days are behind me, even though there are some possible, though not validated side effects. My use of 'middle aged' is a bit optimistic btw, as there's not too many guys I know living to over 100 !

Anyways. can I ask your opinion on some things about it.

1. With the research forthcoming, do you think it is best to hold off on a trial of Testosterone until we we see if research unearths other approaches or appropriate / treatment.
2. If a minor trial is a no-brainer, does one just buy patches off Amazon or are you under a Doctor's regime with a more involved intake of testosterone or (HRT type approach). I probably wouldn't do it, if I have to get my GP's buy in, as I would prefer to hold my next main interaction with him, until the research report lands later this year.
3. If using basic testosterone while also using Niacin weekly, is there anything else to consider re: interactions or contras?

[FloppyBanana]

Ways to increase progesterone (I have not tried any with conviction yet)?
http://youqueen.com/life/health/top-7-natural-ways-to-increase-progesterone/

[demografx]

Hi Demo,

With testosterone (and your positive experiences), it is tempting to think about a trial of this, as it appears from some searches, that middle aged blokes can benefit cognitively and my own child rearing days are behind me, even though there are some possible, though not validated side effects. My use of 'middle aged' is a bit optimistic btw, as there's not too many guys I know living to over 100 !

Anyways. can I ask your opinion on some things about it.

1. With the research forthcoming, do you think it is best to hold off on a trial of Testosterone until we we see if research unearths other approaches or appropriate / treatment.
2. If a minor trial is a no-brainer, does one just buy patches off Amazon or are you under a Doctor's regime with a more involved intake of testosterone or (HRT type approach). I probably wouldn't do it, if I have to get my GP's buy in, as I would prefer to hold my next main interaction with him, until the research report lands later this year.
3. If using basic testosterone while also using Niacin weekly, is there anything else to consider re: interactions or contras?

Hi Colm,

I'm really not qualified to offer an opinion on holding off T-testing for POIS or not (I even approached the manufacturer of my testosterone patches to do a POIS study but I didn't get very far). Or niacin interaction. For some time, I think these will be  *individual* decisions by each POISer and his doctor (s).

The best explanation is your #2: my treatment involved -- then and now -- a lot of bloodtesting and re-testing (several years now) - under the regime of my endocrinogist (with a major university hormonal testing facility) at first and now with my GP.

[Daveman]

Ways to increase progesterone (I have not tried any with conviction yet)?
http://youqueen.com/life/health/top-7-natural-ways-to-increase-progesterone/

Not sure this would work with men though...

We ARE different

[Colm]

Hi Demo,

With testosterone (and your positive experiences), it is tempting to think about a trial of this, as it appears from some searches, that middle aged blokes can benefit cognitively and my own child rearing days are behind me, even though there are some possible, though not validated side effects. My use of 'middle aged' is a bit optimistic btw, as there's not too many guys I know living to over 100 !

Anyways. can I ask your opinion on some things about it.

1. With the research forthcoming, do you think it is best to hold off on a trial of Testosterone until we we see if research unearths other approaches or appropriate / treatment.
2. If a minor trial is a no-brainer, does one just buy patches off Amazon or are you under a Doctor's regime with a more involved intake of testosterone or (HRT type approach). I probably wouldn't do it, if I have to get my GP's buy in, as I would prefer to hold my next main interaction with him, until the research report lands later this year.
3. If using basic testosterone while also using Niacin weekly, is there anything else to consider re: interactions or contras?

Hi Colm,

I'm really not qualified to offer an opinion on holding off T-testing for POIS or not (I even approached the manufacturer of my testosterone patches to do a POIS study but I didn't get very far). Or niacin interaction. For some time, I think these will be  *individual* decisions by each POISer and his doctor (s).

The best explanation is your #2: my treatment involved -- then and now -- a lot of bloodtesting and re-testing (several years now) - under the regime of my endocrinogist (with a major university hormonal testing facility) at first and now with my GP.

Thanks for your response here Demo :-)