HI i really need some help, i suffer from this since puberty i am 20 years old now and it is ruining my life. i registered to this forum to see if i can get some help.. OK for some reason any time i ejaculate with sex, masturbation or night emission, i get these symptoms for at least a week, day 2/3 is the worst, it effects me both physical and mental in a major way More mental though. depression, intense discomfort,irritability, anxiety and difficult in concentrating also hard to think straight, i also feel weak and it seems almost like it weakens my personality , i really dont know what to do, if i dont ejaculate in any way for a week-2weeks i feel somewhat ok and i get my strength back both mental & physical. its like i must be relising some hormone or SOMETHING that is effecting me. really i dont know. iv been to my doctor about it and he said he has never heard of it. so all ive been able to do is reasearch the internet and iv found out about this condition Post Orgasmic Illness Syndrome... i try not to ejaculate in anyway anymore, and when or if i do i get these symptoms big time...i would say its the depreshion and anxity that bothers me the most but still suffer from the rest of the symptoms mentioned.. Any help or advice i would really appreciate it.. could you inbox me if any.