Author Topic: New Theory - Leaky Prostate & Prostaglandin Overload?  (Read 2831 times)

millstone

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New Theory - Leaky Prostate & Prostaglandin Overload?
« on: March 14, 2020, 02:55:09 PM »
Hi everyone,

A new video just came up on YouTube on March 10 that describes a new theory.

https://www.youtube.com/watch?v=SVBxzaWUVUQ

The theory is that there is a leakage of prostaglandin from the prostate gland during ejaculation.

Prostaglandin is an inflammatory mediator:

https://en.wikipedia.org/wiki/Prostaglandin

When prostaglandins increase in circulation, an inflammatory response happens throughout the body (flu like symptoms).

According to the doc, the treatment is a simple administration of an NSAID (Nonsteroidal anti-inflammatory drugs like aspirin or ibuprofen), and additional testosterone supplementation.

Any thoughts on this?

IMO, this makes a whole of of sense, because my POIS symptoms have only started last summer when I can correlate to a time when I feel like I actually damaged by prostate (it hurt for about two weeks after some extreme sexual activity). I do not actively have a urologist, but I am going to speak with my docs about this and dig in further.

demografx

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Re: New Theory - Leaky Prostate & Prostaglandin Overload?
« Reply #1 on: March 14, 2020, 03:54:23 PM »
millstone, welcome to the forum!
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business

Mushnikk

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Re: New Theory - Leaky Prostate & Prostaglandin Overload?
« Reply #2 on: March 14, 2020, 07:32:21 PM »
I developed a slightly enlarged prostate with dripping after urination not too long before POIS onset for what it's worth

karenin

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Re: New Theory - Leaky Prostate & Prostaglandin Overload?
« Reply #3 on: March 14, 2020, 08:27:17 PM »
Unfortunately it is not as simple as the doctor described for most of the POIS-ers.
POIS wouldn't be such a big deal if NSAID's worked so well for all of us.

drop247

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Re: New Theory - Leaky Prostate & Prostaglandin Overload?
« Reply #4 on: March 15, 2020, 10:52:00 PM »
Wouldn't it be better to treat the blood-prostate barrier instead of treating the inflammation from the prostaglandins in the blood? How could we do that? Why is the barrier leaky?

Igy78

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Re: New Theory - Leaky Prostate & Prostaglandin Overload?
« Reply #5 on: March 16, 2020, 03:14:57 PM »
Do not take ibuprofen while Corona is active, somehow Corona take advantage from Ibuprofen.

millstone

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Re: New Theory - Leaky Prostate & Prostaglandin Overload?
« Reply #6 on: March 18, 2020, 12:48:52 PM »
I didn?t sleep well again last night. I woke up multiple times to use the bathroom (stool and urine), and I couldn?t get back to sleep. I checked my own blood pressure and heart rate, both were elevated throughout the night (been a growing trend the past few months).

It was so bad that I decided to go to my primary care doctor. She fit me in for a same day visit.

She checked my prostate and it?s inflamed and tender. I scheduled with a Urologist for next week.

With that said and what I mentioned above, I?m really starting to think that I damaged my prostate back in the summer of last year when all of these issues really started, and every time I agitate it, my immune symptoms flare up to respond.

I?m wondering if I damaged or blew the semen valves from all the edging / being backed up, and there?s a leak into the blood stream.

I?m thinking that my bowel movements moving at night pass by and agitate the Prostate, which wakes me up, some adrenaline / immune reaction starts pumping, and I can?t get back to sleep. The urine is probably because I can?t hold my bladder because it is enlarged / inflamed.

I will keep everyone updated as things progress.

May not be the problem everyone has on this forum, but it may help some people if it?s Prostate-related (semen leak / prostaglandin leak).