Author Topic: MCAS could be causing POIS?  (Read 1470 times)

Mr Raba

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MCAS could be causing POIS?
« on: January 20, 2024, 01:10:53 AM »
Wow.  I just read this:

“Intriguingly neuropeptide Y – a proposed biomarker in chronic fatigue syndrome – can induce mast cell degranulation and a subsequent lowering of blood pressure. Biaggioni found that POTS (postural tachycardia syndrome) patients with mast cell activation experienced episodes of flushing, shortness of breath, headache, lightheadedness, excessive urination, and gastrointestinal symptoms such as diarrhea, nausea, and vomiting. These symptoms could be set off by such normally innocuous things as standing for long periods, exercise, premenstrual cycle, meals, and sexual intercourse

From
https://phoenixrising.me/myalgic-encephalomyelitis-chronic-fatigue-syndrome/fibromyalgia-trial-shows-promise-for-chronic-fatigue-syndrome-mast-cells-and-ketiotifen-in-fm-and-mecfs/
Simultaneous onset of CFS and POIS since Feb 1993. Married since 1989.

Helped by Immunocal (I explained how to take in previous posts).  Some relief on day one and day two.  It affects neurotransmitters.