Author Topic: Developed POIS after antibiotic use  (Read 11632 times)

Muon

  • Hero Member
  • *****
  • Posts: 583
Re: Developed POIS after antibiotic use
« Reply #270 on: July 31, 2019, 03:04:50 PM »
These things can be tested tomorrow. I didn't get any email back from the clinical trial lab. I've sent another email to them, I'm getting frustrated here. I want access to more parameters. If I get the green light we can discuss which parameters are of interest and start crowdfunding. If I don't get the green light there are still interesting parameters left to choose from like the above mentioned.

Nas

  • Hero Member
  • *****
  • Posts: 854
Re: Developed POIS after antibiotic use
« Reply #271 on: July 31, 2019, 03:28:07 PM »
These things can be tested tomorrow. I didn't get any email back from the clinical trial lab. I've sent another email to them, I'm getting frustrated here. I want access to more parameters. If I get the green light we can discuss which parameters are of interest and start crowdfunding. If I don't get the green light there are still interesting parameters left to choose from like the above mentioned.
Maybe we can start a new crowd fund but this time testing the brain chemistry of POIS?

Simon66

  • Full Member
  • ***
  • Posts: 166
Re: Developed POIS after antibiotic use
« Reply #272 on: July 31, 2019, 10:50:06 PM »
I ended up ordering some GABA powder (Now brand) as it sounds like that is more effective at suppressing dreams than the l-tryptophan.
Disclaimer: Please research all supplements thoroughly and take them at your own risk. I am not responsible for any adverse reaction you may suffer.

Avoid all Fluoroquinolone antibiotics including Ciprofloxacin, Levaquin and Avelox.

Simon66

  • Full Member
  • ***
  • Posts: 166
Re: Developed POIS after antibiotic use
« Reply #273 on: August 03, 2019, 08:07:54 PM »
I'm curious if any has done hair mineral analysis, I did one by Trace Elements inc. I had some doubts about the accuracy of hair mineral tests but the deficiencies are exactly the same as my expensive blood tests.

At the time of the test, I had low Copper and Manganese. Both of these minerals are used in the body to produce antioxidant enzymes called Superoxide Dismutase (SOD). I already know from an expensive antioxidant test I did that my superoxide enzyme is quite elevated suggesting I have a lot of oxidative stress in my body and perhaps mitochondrial dsyfunction.

Has anyone else done hair mineral analysis and found similar deficiencies in copper, zinc or manganese?
Disclaimer: Please research all supplements thoroughly and take them at your own risk. I am not responsible for any adverse reaction you may suffer.

Avoid all Fluoroquinolone antibiotics including Ciprofloxacin, Levaquin and Avelox.

Muon

  • Hero Member
  • *****
  • Posts: 583
Re: Developed POIS after antibiotic use
« Reply #274 on: August 04, 2019, 05:20:53 AM »
I already know from an expensive antioxidant test I did that my superoxide enzyme is quite elevated suggesting I have a lot of oxidative stress in my body and perhaps mitochondrial dsyfunction.

Has anyone else done hair mineral analysis and found similar deficiencies in copper, zinc or manganese?
No but my mitochondrial function has been checked which was fine.

Simon66

  • Full Member
  • ***
  • Posts: 166
Re: Developed POIS after antibiotic use
« Reply #275 on: August 05, 2019, 05:08:22 PM »
Here's my latest list of supplements that I think have an impact on my condition:

1. BB536 Probiotic - I know this has some positive effect on my health, I think it boosts good gut bacteria.

2. Allicin Max (Garlic Supplement) - It feels like this one fights some kind of systemic overgrowth in my body, whether fungal, viral or bacterial.

3. L-Arginine - I think this does something positive at certain times, it may need to be taken with a tiny amount of L-Lysine. L-Arginine boosts Nitric Oxide and is supposedly good for fighting candida albicans infections.

4. Zinc Picolinate - I'm still testing this one, it may clear my skin. My working theory is it boosts the immune system and clears bacterial overgrowth of the skin. People often use zinc to treat acne rather than drugs like Accutane that are known to damage the body.

I had stopped taking the Allicin Max for a few weeks because I didn't feel like it was helping anymore. When I started again today, I had a heavy heartbeat for 2 hours and then I suddenly felt better than I have in a few weeks.

I did the same thing with the BB536 probiotic, I stopped for nearly a month. When I started taking the BB536, the next morning I was coughing up phlegm which from experience feels like my body clearing something.

These strange reactions to Allicin Max and BB536 only happen for the first 1 or 2 days so it really does seem like there is some systemic infection(s) that needs to be kept at bay. I am going to try and find some other supplements that might help and build some kind of artificial immune system since mine really doesn't work properly.

I have already tried Oregano Oil and feel that gave me a bad reaction, it felt like it was worsening whatever overgrowth I have. Oregano Oil does carry warnings that it can kill good bacteria so I guess I should avoid it in future.
Disclaimer: Please research all supplements thoroughly and take them at your own risk. I am not responsible for any adverse reaction you may suffer.

Avoid all Fluoroquinolone antibiotics including Ciprofloxacin, Levaquin and Avelox.

Simon66

  • Full Member
  • ***
  • Posts: 166
Re: Developed POIS after antibiotic use
« Reply #276 on: August 11, 2019, 08:42:36 PM »
I'm aiming to take an extended break from posting on this forum. My problems are somewhat more complicated than POIS due to the antibiotics I took.

My protocol for the next few months is going to include the following:

1. Some combination of L-Arginine and L-Lysine: I haven't worked out the ideal dose yet. I need to be careful not to damage my kidneys with too many supplements.

2. BB536 Probiotic: I have some expensive high strength probiotics that I get from Japan, I've added images of the new (black box) and old (blue box) packaging below. I will be taking one sachet (50 billion cfu) per day for a few months.




3. Miscellaneous Supplements: I will probably rotate some supplements like Allicin Max (Garlic pills), a child multivitamin and may experiment with some fruit powders for their antioxidant bioflavonoid properties. I have a few other probiotics that I may use in combination with the BB536 such as L. Reuteri (Biogaia), L. Plantarum 299v (Jarrow Ideal Bowel Support) and L. Acidophilus (Lindens Pro Bio Live Max).

I still believe the gut has a lot to do with my issues. I know from testing my antioxidant enzymes that I have high levels of oxidative stress in my body which seems to manifest as connective tissue damage (spontaneous bruising, slight muscle tears & burning nerve sensations) and maybe other things like fatigue, poor sleep and low mood. When the oxidative stress was very high, I would get pain in my neck/ear cartilage and could feel that the cartilage was missing in these areas. After months of recurring neck pain, the hyoid bone in my neck actually started to come loose and now occasionally clicks out of place when I swallow food or water. During this horrible period, I discovered that taking the probiotic BB536 at 2 billion strength seemed to bring me instantly out of this state whereas taking Bacillus "spore probiotics" would put me back in that bad state. I bought a month's worth of this BB536 probiotic at high strength (50 billion daily) and took it intermittently over the next 5 months. During this period, my health improved significantly but I cannot be certain that this probiotic was the cause.

Long story short, I am going to be concentrating on taking 50 billion per day of this BB536 probiotic for probably 4 months and then I will report back with my findings. I want to see if it is possible to recover my health to levels I haven't seen in 20 years just by targeting gut health.
Disclaimer: Please research all supplements thoroughly and take them at your own risk. I am not responsible for any adverse reaction you may suffer.

Avoid all Fluoroquinolone antibiotics including Ciprofloxacin, Levaquin and Avelox.

b_jim

  • Hero Member
  • *****
  • Posts: 940
Re: Developed POIS after antibiotic use
« Reply #277 on: August 12, 2019, 08:50:54 AM »
It's not sure probiotics can influence microbotia.
There are pro and cons.


The first argument was stomach acid kill most of bacterias.
But some studies show some bacterias have a good resistance and a part of them (1% to 20% ?) can cross the stomach alive.
And of course, you can use gastro-resistant caps.

The second was even if you take billions of bacterias it"s few compared to the whole microbiota.
And even if you can influence it's a temporary effect. Microbiota keep its homeostasis.
The real way to make a real change is microbiota transplantation.
But it's a very recent science and under severe controle.
Unbalanced microbiota could lead to disease or death.

So, I 'm not sure these complements are usefull. Maybe, maybe not. Some doctors use the word "psychobiotics" so the influence migh be real.
But the easy way to have a good microbiota is to eat tons of organics fruit, vegetables and plants. Nature, cooked, sprouted, lacto-fermented...

Taurine = Anti-Pois

Simon66

  • Full Member
  • ***
  • Posts: 166
Re: Developed POIS after antibiotic use
« Reply #278 on: August 12, 2019, 05:46:49 PM »
Hi b_jim,

I have been doing a lot research on gut bacteria. From what I've read, the gut ecosystem is fully developed by the age of 4 years old and the bacterial strains are then not easily changed from that point.

I guarantee you that most probiotics reach the gut intact, I can feel the effects on the day after I take them. The real question is whether the supplement has been stored badly by the seller and the bacteria have died. The strain of bacteria is also very important, people think buying a probiotic with 30 strains is better than a single strain product but those 30 strains might be taken from a pig's gut and not be very effective in humans or those strains could not be well studied or they might interfere with each other. The BB536 I take is from a human gut, it was compared alongside a number of other human bacteria and found to have the best beneficial properties for human health.

I did a lot of research into microbiota transplantation (FMT), it seems like the effects for that might be temporary. I wrote a list of issues I have with FMT in this thread a while ago, there's a lot of problems they need to fix before I would ever try it.

The psychobiotics, as I understand it, refers to probiotics that can improve mood. I have a few probiotics that claim to improve mood called "Zenflore" and "Florassist Mood", they seem to all be strains of Bifidobacterium Longum. My BB536 probiotic is also a strain of B. Longum and seems to help my mood. I do think there is a link between gut dysbiosis and mental disorders like depression.

My experience of probiotics is that they can shift your bacteria in a positive direction but they do not colonise the gut permanently so they need to be supplemented regularly, the main difficulty is finding one that is effective for your particular gut. I have taken prebiotics like FOS, GOS and inulin but it feels like these feed the bad bacteria too. I also react badly to fermented foods and I think this may be because of the large amounts of fungi they contain, it is suggested that anyone with SIBO should avoid fermented foods.

To put my experiences simply, I have been seriously ill and tried everything possible to improve my gut (excluding FMT). Finding an effective single-strain probiotic like BB536 appears to have gradually corrected my gut imbalance and I will probably have to take it for life, which is fine by me despite the cost. I think I was on the very extreme of gut dysbiosis, pretty much anything I consumed would trigger severe issues resembling autoimmune disease and I suppose that is because I don't have much good bacteria left. I seemed to tolerate BB536 so I kept upping my dosage and now I can eat most foods. I still have trouble with fermented foods, possibly because they contain large amounts of bacteria and yeast which undermines the effects of the BB536.

When the providers of FMT fix the many issues with the procedure, I will gladly consider trying it. I still get the impression that the human gut doesn't easily allow new strains to colonise permanently so maybe the effects of FMT wear off after 2 months. I think in the future they will just put the FMT bacteria in a capsule and people will take it everyday like a multivitamin, it will be a 1000 strain probiotic. The other future technology with hopefully be Human Milk Oligosaccharides, these are the natural prebiotics found in human breast milk that help babies to build a gut ecosystem.
Disclaimer: Please research all supplements thoroughly and take them at your own risk. I am not responsible for any adverse reaction you may suffer.

Avoid all Fluoroquinolone antibiotics including Ciprofloxacin, Levaquin and Avelox.

b_jim

  • Hero Member
  • *****
  • Posts: 940
Re: Developed POIS after antibiotic use
« Reply #279 on: August 18, 2019, 10:10:07 AM »
I'm happy if it works for you. Keep us informed next months.  8)
Taurine = Anti-Pois