Hello, I have been suffering from POIS for over 10 years, but I do not find myself in the cases I read here, I have all the symptoms, but I personally remove 100% my symptoms exclusively with a hard physical training session, it is not necessary either long, the important thing is that it is intact and that it involves the whole body. I discovered that I was comfortable with training by chance, I tell you ... I started to ejaculate around the age of 12, I remember that the first heavy and debilitating exhaustion I had it around the age of 14, with a peak around 16 -18 years. what I did was to have an orgasm on Saturday night and stay in bed all Sunday, doing nothing except eating and going to the bathroom. one night, however, I had a nocturnal orgasm and since that day I have been ill for months, the symptoms did not go away, I made countless analyzes in which I seemed to be in good health. as a last alternative I tried intensive training and solved the problem until the next ejaculation. while obviously as other users report a simple light workout does not give me benefits, in practice I overcome the initial fatigue every time until magically I can not feel good. My idea is that during orgasm my body releases a substance in abundance that I can not assimilate or that my body reacts to a substance released by my body with an immune response or something similar. I also add that for me sleep helps to alleviate the symptoms, the hot shower is indifferent to me, the FANS are totally ineffective. I also add that the symptoms occur only after I receive the impulse of the orgasm, if I stop before I ejaculate I'm fine (if I could never ejaculate you will never do it and I would have solved). I also devised a technique that takes several hours to expel the same amount of sperm and liquid without actually having an orgasm, in this case I'm fine, but it is not a method that really helps me because it takes me several hours every time, and it's not workable with a partner. I am writing to you both to spread my case in case it could be used, or to ask you desperately for a remedy. Lately I was thinking of having many orgasms in order to get addictive from the substance that I probably can not metabolize released during orgasm (I do not know what it is or may be), the problem is that at this time I would be literally unfit for society, but for now it is my last hope. Of course, my relationship with the couple has ceased all because of this disease, and I have come to the point of not wanting to be with anybody because I already know how it will almost certainly end. I apologize if someone has already answered other posts that I have not read, but my English is bad, and I'm doing everything possible to read more. I do not deny that when I found this forum I also burst into tears from the hope of being better. In my country doctors do not even know the pathology, not even by name or by hearsay.