Author Topic: POIS trigger other than O? Refining for antigen origin  (Read 4110 times)

Quantum

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POIS trigger other than O? Refining for antigen origin
« on: November 30, 2014, 09:15:39 PM »
Did you ever have POIS symptoms triggered by something other than O, like liquid dribbling from the urethra while passing a large stool (either milky white prostate fluid, or clear pre-ejaculate fluid), or after arousal have made pre-ejaculate fluid dribbling, or by simply defecating or urinating?

On the other, mention if you have had any kind of leeking fluid that DID NOT triggered POIS.  That would help as well.

This survey is to narrow as much as possible the search for the possible location from which the antigen comes from.  See this info pasted here from another thread:


Is there anyone out there that has seen a decrease in POIS symptoms after having a vasectomy?

Hi Pflug, and everyone,

I had a vasectomy 11 years ago.  I did hope that it would help with my POIS, but it didn't change a thing.

This fact can help in refining the search in order to find the original location of the antigenic substance that triggers the hypersensitivity reaction, if there really is an immune reaction at play. If vasectomy have no impact on POIS, this would be a possible hint that the antigen is not coming from the testis, and neither from the epididymis nor the Vas deferens - it has to come from further downstream the male anatomy. This would mean that surgical removal of the testis, or the epididymis, or vas deferans (as in vasectomy) - are not useful for relief of POIS. On the other hand, removal of the prostate, seminal vesicles and bulbourethral glands could be successful for the relief of POIS, if I draw accurate inferences from the fact that vasectomy has done nothing for me ( and neither for EDS), and that some surgical treatments including removal of a part of the prostate, seminal vesicles and the bulbourethral glands have been successful in completely eliminating POIS, at least in one individual ( https://www.youtube.com/watch?v=6sdaR18vw1s&feature=youtu.be&list=UUJpZW40Di0JEcM1_SUtw55w , thanks to FloppyB for the link)

This hypothesis that the antigen comes from more downstream is furthered supported by the fact that some forum members develop POIS symptoms after a bowel movement (example: http://poiscenter.com/forums/index.php?topic=1032.0 ).  The prostate and urethral glands are just beside the rectum, so if you pass a large and hard stool, it will put a pressure on those, and you may see some drops of liquid dribbling from the urethra (it happens in healthy men as well, it is just a mechanical phenomenon ).  If the liquid is colorless, it is pre-ejaculate coming from the bulbourethral glands (Cowper glands), and if it is white and milky, it is prostatic fluid.  It may be a mix of the two, as well.  This phenomena tends to happen more often when you have refrained form sexual activity for a while, because the prostate is more loaded with fluid.

Some forum members have also stated that they can experiment some POIS symptoms when sexually aroused, or beginning to experiment some POIS symptoms before orgasm, during sexual activity.  That would indicate that the pre-ejaculate fluid from the bulbourethral glands can trigger some low grade POIS, so ti would contain the antigen.  I would like more input on that, for sure.

From the immune theory perspective, that would narrow the search for the source of the antigen to either the prostate, or the bulbourethral glands, or both.

It would be very interesting to have more forum members feedbacks about this kind of "leaking" phenomena.  In my own case, those "prostate leaks" do not trigger any POIS symptoms, so I cannot tell.  I never had "bulbourethral glands leaks", and never noted POIS symptoms before actual orgasm, but it is claer that I produce very limited quantity of this pre-ejaculate (this vary from one man to another)  As both fluids mix when ejaculation occurs, it is hard to make a clear statement for myself.

I also suppose that, for those who have rather constant POIS symptoms, even when not ejaculating, that they may constantly "maintain" their POIS symptoms because of defecating, and urinating too ( I think i read about a member reporting POIS induction after urinating each morning).  Even if no fluid appears out of the urethra, that doesn't exclude that some has leaked out in the urethra, without reaching out.  This would be enough for very sensitive POIS sufferers to have symptoms triggered regularly, making it a low-level, chronic POIS.

Any comments about this?

If some members have had POIS symptoms after having fluid dribbling from their urethra, after defecating or in other situations different from O, please share if this liquid looked like prostate fluid (white, milky ) or pre-ejaculate (colorless, and more liquid).  I would be interested to see how far we can narrow the search for the location of the possible source, or sources of the antigen.

Should I create a new thread for asking this question?  Has it already been asked and discussed before ( I am far from having read everything on this forum) ?

Thanks,

Quantum

You should create another thread, I dont think any one has created a similar thread with that much detail

Thanks in advance for your inputs

Quantum
 
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Quantum

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Re: POIS trigger other than O? Refining for antigen origin
« Reply #1 on: November 30, 2014, 09:23:32 PM »
I repost here some info from the previous thread:


Some forum members have also stated that they can experiment some POIS symptoms when sexually aroused, or beginning to experiment some POIS symptoms before orgasm, during sexual activity.  That would indicate that the pre-ejaculate fluid from the bulbourethral glands can trigger some low grade POIS, so ti would contain the antigen.  I would like more input on that, for sure.

From the immune theory perspective, that would narrow the search for the source of the antigen to either the prostate, or the bulbourethral glands, or both.


I think the main two suspects would the Seminal vesicles and the prostate. For clarity a radical prostatectomy (total removal of prostate includes removal of the Seminal vesicles). This op is done mainly to maximally eliminate cancer risk.

(...)

Animus (who had the operation) did not have the cowpers gland removed and achieved 100% POIS elimination. For me I can get the clear lubricating liquid which I believe comes form the cowpers gland. I get quite a bit of it quite quickly and if I stop getting aroused it will not cause POIS symptoms. If I have sex for a long time without ejaculating I can get very mild POIS (this does contradict slightly previous posts I have made. The POIS is minimal here though). So for me at least I think the problem is further up stream.

Hi FloppyB,

The case you mention means that Cowpers Gland (bulbourethral glands) may not be the culprit, or show, at the least, that they are not always involved.  If members confirm that pre-ejacuate do not cause POIS symptoms, that will make it to only two possible culprits for the origin for the antigen:  the prostate or the seminal vesicles. 

I think it would be interesting to follow CertainlyPOIS advice and move this discussion in a new thread.

Thanks for your interesting feedback, FloppyB


********

Mine is milky white, but it does not produce any obvious symptoms.


Same for me, milky white, and no symptoms.  But I think i remember having read on the forum about members who did have symptoms in this situation.  Maybe more feedbacks from members will help getting a better perspective on this.

Quantum


You are 100% responsible for what you do with anything I post on this forum and of any consequence it could have for you.  Forum rule: ""Do not use POISCenter as a substitute for, or to give, medical advice" Read the remaining part at http://poiscenter.com/forums/index.php?topic=1.msg10259#msg10259

Labyrinth

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Re: POIS trigger other than O? Refining for antigen origin
« Reply #2 on: April 08, 2015, 01:54:48 PM »
in my case the antigens that causes pois like symptoms are from rice i get reaction from rice . wheat . chicken . eggs . fava beans . i did research in that and i found all of them contain lectins ????
POIS of 10 yrs now