TRH

[b_jim]

TRH = Thyrotropin-releasing hormone

TRH is present in human sperm :
Human semen contains TRH
Anti-depressant role of semen

Can the TRH loss by ejaculation could explain some Pois Symptoms ?

Wikipedia :  TRH has been used clinically for the treatment of spinocerebellar degeneration and disturbance of consciousness in humans.

it is suggested that NS-3 ( = TRH-like hormone )may restore the disturbance of consciousness by activating the brain dopamine, noradrenaline and acetylcholine neurons without stimulating these receptors directly.

Non-scientific quote :

One simple neurohormone is TRH. It's involved in the control of temperature, as it controls energy homeostasis. TRH causes wakefulness and loss of appetite. It's also found in pancreatic islets and the gastrointestinal tract, where it increases motility, notably in women with irritable bowel syndrome. It's released when stressed in an effort to keep the body in homeostasis.

TRH stimulates the pituitary to secrete prolactin. Excess levels of TRH inhibit dopamine, which also causes prolactin to increase. Excess oestrogen causes prolactin to rise too. Excess prolactin inhibits dopamine. Although prolactin is the hormone of lactogenesis, it's also an inflammatory hormone. A drop in dopamine can lead to anxiety and depression.

TRH also stimulates the release of noradrenaline from the frontal cortex, and the pituitary to release thyroid-stimulating hormone (TSH).

TSH stimulates the thyroid to secrete thyroxine and triiodothyronine which control the bodys metabolic rate, heat generation, neuromuscular function and heart rate.

Progesterone stimulates TRH :

Progesterone increased spontaneous and TRH-induced release of PRL and TSH in vitro

High concentration ?
http://www.ncbi.nlm.nih.gov/pubmed/2117583

Thyrotrophin-releasing hormone (TRH) and related peptides occur in high concentrations in human semen.

[Prancer]

Cool, thanks for sharing this with us b_jim

[b_jim]

Yes, maybe it could be nice to test trh in blood after ejaculation.
Maybe some Pois sufferers have tested it or write something about this hormone. I don't know I'm just discovering it.