Study: POIS and Delayed Onset Muscle Soreness (DOMS)

[M.F.M]

Yes if i am only sure about one thing that causes pois , is wet ejaculation after puberty , because before puberty when i masturbated  i didnt suffer any pois symptoms , i was playing wrestling and always got straight A?s in all my subjects with alot of ease

After puberty on the other-hand the correlation between ejaculation and  pois symptoms were quite obvious to me , specially brain fog , i couldnt even count change if i am buying something from the store, you can imagine how school and exams and socializing were , physical symptoms such as muscle weakness and aches were present too , but the most traumatic experience for me was and still is the brain fog 

[mike_sweden]

my weak orgasms cause much less pois

also abstaining and then doing one orgasm makes the pois less severe

[demografx]

Anyone tried this supplement yet ? Sperminide ?? What a name !

[Journey]

Yes if i am only sure about one thing that causes pois , is wet ejaculation after puberty , because before puberty when i masturbated  i didnt suffer any pois symptoms , i was playing wrestling and always got straight A?s in all my subjects with alot of ease

After puberty on the other-hand the correlation between ejaculation and  pois symptoms were quite obvious to me , specially brain fog , i couldnt even count change if i am buying something from the store, you can imagine how school and exams and socializing were , physical symptoms such as muscle weakness and aches were present too , but the most traumatic experience for me was and still is the brain fog

EXACTLY THE SAME HERE

I discovered masturbation before my body could produce semen

And before that I had dry orgasms and ZERO POIS SYMPTOMS

I could do it 3-4 times a day and feel fine completely

POIS researchers must research how start of semen/prostate fluid production/sexual maturation/puberty are involved in the appearance of POIS

I wonder if someone has managed to turn off semen/prostate fluid production somehow and emulate the pre-puberty dry orgasms and see if they give POIS

[berlin1984]

Since cutting out linoleic acid (seed oils / fried foods etc) around 1 year ago, I don't have this anymore.
Also no pain in morning-after-orgasm waking up.
I try to exclusively cook with coconut oil and have only butter as fat source plus beef/lamb meat. (No chicken, ideally no pork but that's hard)

Read more here: https://poiscenter.com/forums/index.php?topic=427.msg42713#msg42713

It takes a while to change your body composition away from those bad fats.
https://www.google.com/search?q=PUFA+detox

I go to gym or swimming now every second/third day without pain.

[Cursed]

Another thing to consider when talking about PUFA is vitamin E. The more PUFA you eat, the more you need. And even when you change your diet, your vit E requirement remains increased for a year (or even two, can't recall how long exactly) if you were on a high PUFA diet. Just don't go overboard with it, most supplements have waaay too much.

[Rock76]

So none tried a spermidine supplement ?

[Muon]

Berlin, could you move this thread to the articles, references and links category? It discusses a specific POIS paper.

[Progecitor]

So none tried a spermidine supplement ?

At least two of us had tried spermidine, but only for a few days, without much results:
- berlin1984
https://poiscenter.com/forums/index.php?topic=3652.msg41815#msg41815
- Progecitor (me)
https://poiscenter.com/forums/index.php?topic=3798.msg44131#msg44131

I think it is worth mentioning that recently spermidine has been much discussed as an anti-aging supplement. This is associated with its ability to induce autophagy, which removes cellular debris (toxic protein aggregates, damaged organelles) maintaining a healthy homeostasis. For this very reason it is also considered in the treatment of neurodegenerative diseases. I think this means it could be a good supplement when taken long-term, but one shouldn’t expect any miracle by taking it only on-demand. Sirt1 activators also induce autophagy and I generally had success with them. Though of course other possible mechanisms for spermidine have been already mentioned on the site.

[Journey]

Since cutting out linoleic acid (seed oils / fried foods etc) around 1 year ago, I don't have this anymore.
Also no pain in morning-after-orgasm waking up.
I try to exclusively cook with coconut oil and have only butter as fat source plus beef/lamb meat. (No chicken, ideally no pork but that's hard)

Read more here: https://poiscenter.com/forums/index.php?topic=427.msg42713#msg42713

It takes a while to change your body composition away from those bad fats.
https://www.google.com/search?q=PUFA+detox

I go to gym or swimming now every second/third day without pain.

Ray Peat has talked of it

PUFAs are used to produce inflammatory molecules by body including prostaglandins if I'm not mistaken

I wonder if full PUFA depletion combined with a pro-Metabolic Ray Peat diet could cure POIS

[Miyagi]

An opinion on this article, by a friend in pm:
"Thanks for the article. I disagree with a lot of statements made there. First of all, theoretical studies without any experiments on mouse or human  models (gene expression, not readily available blood tests etc.) are the pathway to nowhere. With the same success, I could attribute every POIS symptom to the loss of zinc in sperm. Pseudoscience seeks to prove a hypothesis correct whereas science seeks to prove it wrong. Moreover, I highly dislike the approach where they try to explain all POIS cases. This theory could be easily declined by simply providing cases where people experience POIS-symptoms just from arousal, and all that spermidine stuff goes into nowhere. This theory can't explain how so many people experience symptomatic relief from such substances as SSRIs, benzos, etc., neither how people were cured by specific dietary protocols. That said, I do not disregard the theory, but this study is completely inappropriate and can't be taken seriously. From my perspective, it is a bro-science anecdote."

I agree with the methodological criticisms, though I still welcome new ideas which can bring about further reflection.

Wow, great read! Thank you mystery writer. It's rather rare to read a comment online and think loudly to myself "HAHA YES, THAT'S SO TRUE HAHA".

Anyway, i for the past few months have been testing the theory that the body fault causing pois is inside the stomach...specifically related to acid regulation. /my2cent