There are two well-discussed YouTube videos of men solving their own POIS problems.
One was solved by resetting his gut microbiome with daily enemas, a period of fasting / modified vegetable diet, and probiotics:
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https://www.youtube.com/watch?v=ISnnag8UOGwThe other healed after long term abstinence and subsequent "discovery" of his healing after a nocturnal emission with no symptoms (after 4 years of celibacy):
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https://www.youtube.com/watch?v=t87dsMDXPZ4&t=308sThere are reports on other websites and forums of POIS being completely cured from a variety of techniques:
* Meditation / OM Chanting
* Panchakarma Cleanse
* Use of Orgonite / Orgone Energy
* Wim Hof Breathing / Similar Techniques
* Healing / Stimulating / Deflating the Vagus Nerve
* Prostate Treatment
* Elimination of Some type of Bacterial or Viral Infection from the body (e.g. removing rotten wisdom teeth, eliminating fungus or bacteria from the gut, etc)
Most contributors on this forum see POIS as a completely medical / physical phenomenon, so the validity of some of the above methods would be strongly debated.
"Treatment" methods are found throughout this forum which focus on reduction or prevention of the inflammatory immune response that happens after orgasm. Common supplements / remedies include:
* Taurine
* Niacin
* Testosterone Supplementation
* LDN (opioid receptor modulation)
* Alpha Blockers (prostate / blood pressure meds)
* Cromolyn Sodium
* NSAIDs / Steroids
These treatments simply suppress the symptoms, not solve the underlying problem.
The "reason" for POIS, according to nanna1 in a very popular thread, "occurs when there is an overexpression of the α1-adrenergic (a1A) receptor and a subsequent over-stimulation of a1A by rising norepinephrine levels. [during sexual activity / orgasm]"
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https://poiscenter.com/forums/index.php?topic=2502.0The question for each individual in pursuit of a cure would be "what led to the over expression of their a1A receptors, and can it be reversed?"
I am personally starting to really believe that the inflammatory immune response is connected to some level of trauma and resulted in maladaptive limbic system cross-wiring, similar to how Fibromyalgia / CFS / Lyme / auto-immune conditions are primed and manifest. Here is a great video on how chronic conditions start and develop:
https://www.youtube.com/watch?v=C5tE218DIhsAn overly simplified explanation is that this is due to mixed trauma and your body's chemical state at the time, or in other words "the perfect storm". The brain's Limbic System set up a hard-wired program that correlates the hormones / chemicals released from orgasm with a perceived threat, and kicks off the immune / inflammation response because of the conditions it "remembers" in the body at that time. This is really confused programming, as the orgasm isn't the threat, but it mimics the conditional memory of the threat at that time, including prolonged stress, which repeated over and over, "kindling" or sensitizing the response each time.
There very well could be a multitude of reasons that POIS happens to individuals, and not every case / reason is the same.
Over-expression of the a1A receptor can be linked to chronic stress, as alpha blockers are also prescribed for PTSD:
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https://en.wikipedia.org/wiki/Alpha-1_blocker*
https://www.sciencedirect.com/science/article/pii/S0006322399001389This could be similar to the "kindling effect" that Gary Wilson warns about on the NoFap / Porn Addiction literature. Hypofrontality, anxiety, receptor over-expression / under-expression in the prefrontal cortex related to addiction behaviors. Many POIS symptoms are very much like withdrawal symptoms that are experienced when detoxing from alcohol or benzodiazepines.
Here is a good "scare" article that speaks to the potential damage of over-ejaculation as well. Sounds like POIS to me:
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http://boys-private-health.blogspot.com/2010/07/damage-of-orgasms.html?m=1I myself am personally focusing on gut health and limbic-system rewiring techniques, as my POIS developed after a series of prolonged chronic stress and other environmental factors that happened all at once, specifically viral load, food poisoning, and taking a broad spectrum antibiotic that I never had before.
This "rewiring" approach is literally "mind-over-matter", so you have to fully believe this is possible if you wish to pursue it. The YouTube video I noted above is from a rewiring course called the Gupta Program:
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http://guptaprogram.com/I am personally working through the Dynamic Neural Retraining System, which seems similar:
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http://retrainingthebrain.com/I'm not really endorsing one over the other, or endorsing neural retraining over general medical approach (I am also working with a handful of doctors to see if there is a medical root cause), but I do believe the mind is a powerful thing. It really has the capacity to heal the body and you can reprogram how your limbic system kicks off your fight or flight systems that result in inflammation and chronic stress.
Anyway, welcome to the forum. I'm sorry for the conditions that brought you here, but am glad you have found this support system to aid you on your healing journey.
