Yes, B_Jim, absolutely.
I'm in POIS now, and prior to that I had been working in a position that is difficult for the neck and upper back. Although before the POIS, I did notice a bit of tension in the area it passed. But now that I'm in POIS, it's barely supportable.
Other times it's the elbows from previously chopping wood or arms from throwing the 4 yr old in the air like he likes to do.
The POIS inflamation exagerates any sensitive tissue. Perhaps there's a histamine build up in the tissues that reacts with POIS.
Maybe that's why the Niacin works so well, it does a pre-flush of the stored histamines in a controlled way!