the syrup (Apidone) im currently using is a mix of chlorphenalamine maleate(anti histamnic) and Dexamethasone(glucocorticoid) and its working well but i experience some side effects of the drug so its not totally safe but its worth it.
taking it before orgasm works better than taking after orgasm. It literally stops my post-ejaculation madness. even outside POIS, it helps with the my POIS chronic effects. I dunno which ingredient play the main role but I guess they both do.