Author Topic: Summary of Treatments  (Read 63392 times)

Daveman

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Re: Summary of Treatments
« Reply #30 on: August 01, 2012, 08:32:56 AM »
Again, I dont know if this is a permanent fix, but as its been almost 24 hours with barely any symptoms, I still have a smile on my face. I am a grad student and was extremely inspired by the abc documentary featuring the Spanish student that started taking niacin and changed his life.

http://www.abc.net.au/catalyst/stories/3474801.htm


Hi simplethingsinlife! I am the spanish student who appears in the video, i  am really glad that niacin has worked on you, too! I have another smile in my face due to your success  ;D

Thanks Observer for all you do. Simplethings, Observer is another member who not only posts regularly, but works hard in the background to move and shake our POIS movement! The time required is WELL paid when we see a new member like yourself coming to join in on the relief and benefits that we together can provide.

We have an Indiegogo campaign just about ready to come out, probably this week! I would LOVE to see another $10,000 come in from that.


WITHOUT RESEARCH THERE WILL BE NO CURE!
Sessions 5 to 9 days, mostly Flu-like, joints, digestion problems, light cognitive.
Niacin has changed my lif though, now 1 day MAX.
Somewhere in this interaction with Niacin is the answer!

Going less Crazy

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Re: Summary of Treatments
« Reply #31 on: August 21, 2012, 10:34:49 PM »
I was wondering if we can change something in the summary treatment of niacin.  Maybe we can add a general procedure on how people are taking it.  eg.  "have an O an hour after flushing"  or maybe a recommended amount to start with if you are first trying it.  I don't take niacin to ofter but I am going to start and I really need to know the general "niacin taking" procedure.
My POIS managed with modified Paleo Diet (@ diet that 100% manages my pois)Believe my POIS stems from inflammation in the gut. O and stimulation = neuro POIS from inflammation from the gut.

I take <1/4 drop of a 10mg liquid Zyrtec gelcap every night and it has vastly improved my sleep and energy.

Ccconfucius

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Re: Summary of Treatments
« Reply #32 on: August 22, 2012, 11:02:00 AM »
I was wondering if we can change something in the summary treatment of niacin.  Maybe we can add a general procedure on how people are taking it.  eg.  "have an O an hour after flushing"  or maybe a recommended amount to start with if you are first trying it.  I don't take niacin to ofter but I am going to start and I really need to know the general "niacin taking" procedure.

good idea i will get on that.

for time being i believe you use it and wait untill all the flush is gone before orgasm. 
Using it on an empty stomach is the best. 
if you eat wait\ 4hrs before using it.
go on niacin thread it has lots of information

kurtosis

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Re: Summary of Treatments
« Reply #33 on: August 22, 2012, 11:37:43 AM »
I was wondering if we can change something in the summary treatment of niacin.  Maybe we can add a general procedure on how people are taking it.  eg.  "have an O an hour after flushing"  or maybe a recommended amount to start with if you are first trying it.  I don't take niacin to ofter but I am going to start and I really need to know the general "niacin taking" procedure.

good idea i will get on that.

for time being i believe you use it and wait untill all the flush is gone before orgasm. 
Using it on an empty stomach is the best. 
if you eat wait\ 4hrs before using it.
go on niacin thread it has lots of information

Oddly enough the early orthomolecular psychiatry researchers (early to mid 70s) published some papers where they say the peak prostaglandin output from niacin consumption occurs after about 3-4 hours.

Daveman

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Re: Summary of Treatments
« Reply #34 on: August 22, 2012, 12:38:51 PM »
I was wondering if we can change something in the summary treatment of niacin.  Maybe we can add a general procedure on how people are taking it.  eg.  "have an O an hour after flushing"  or maybe a recommended amount to start with if you are first trying it.  I don't take niacin to ofter but I am going to start and I really need to know the general "niacin taking" procedure.

good idea i will get on that.

for time being i believe you use it and wait untill all the flush is gone before orgasm. 
Using it on an empty stomach is the best. 
if you eat wait\ 4hrs before using it.
go on niacin thread it has lots of information

Oddly enough the early orthomolecular psychiatry researchers (early to mid 70s) published some papers where they say the peak prostaglandin output from niacin consumption occurs after about 3-4 hours.

Who's up for doing that experiment.... waiting those 3 or 4 hrs!!

I would, but I'd fear that it might not work. I don't want more POIS!!

But I assume by your comment that it is the prostaglandin output that is so involved in the process!
WITHOUT RESEARCH THERE WILL BE NO CURE!
Sessions 5 to 9 days, mostly Flu-like, joints, digestion problems, light cognitive.
Niacin has changed my lif though, now 1 day MAX.
Somewhere in this interaction with Niacin is the answer!

Daveman

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Re: Summary of Treatments
« Reply #35 on: August 22, 2012, 12:44:20 PM »
BTW Kurtosis,

When I was younger and more foolish  ;D, I used to take B-Complex and vitamin C before going out to party. They had said that it reduces the hangover.

I would take one pill (fairly strong does, but don't remember the amount) and 1000mg vit C a few hours before going out, another during and another before going to bed.

But by "goodness" it worked. My hangovers were about 25% of what they should have been.

It felt sort of like magic, and it feels like the saem magic that happens with niacin.

What could be happening there?

WITHOUT RESEARCH THERE WILL BE NO CURE!
Sessions 5 to 9 days, mostly Flu-like, joints, digestion problems, light cognitive.
Niacin has changed my lif though, now 1 day MAX.
Somewhere in this interaction with Niacin is the answer!

kurtosis

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Re: Summary of Treatments
« Reply #36 on: August 22, 2012, 02:36:22 PM »
BTW Kurtosis,

When I was younger and more foolish  ;D, I used to take B-Complex and vitamin C before going out to party. They had said that it reduces the hangover.

I would take one pill (fairly strong does, but don't remember the amount) and 1000mg vit C a few hours before going out, another during and another before going to bed.

But by "goodness" it worked. My hangovers were about 25% of what they should have been.

It felt sort of like magic, and it feels like the saem magic that happens with niacin.

What could be happening there?



Oddly enough, prostaglandin inhibition, getting some water to dilute the alcohol and b vitamins to replenish what's used up by the alcohol. Vitamin C stimulates and inhibits prostaglandin release depending on the source of the synthesis.
See http://www.ncbi.nlm.nih.gov/pubmed/1492101
It's why GoingCrazy got some relief from Vit C (I think :))

That was one of the reasons I got fixated a few years back on the idea this was all to do with candida producing alcohol in my gut. POIS and alcoholism appear to have similar symptoms but without the partying and waking up in strange places. With POIS, the strange and unfamiliar place you wake up in is probably your own bed. Doh!

kurtosis

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Re: Summary of Treatments
« Reply #37 on: August 22, 2012, 02:48:49 PM »
I was wondering if we can change something in the summary treatment of niacin.  Maybe we can add a general procedure on how people are taking it.  eg.  "have an O an hour after flushing"  or maybe a recommended amount to start with if you are first trying it.  I don't take niacin to ofter but I am going to start and I really need to know the general "niacin taking" procedure.

good idea i will get on that.

for time being i believe you use it and wait untill all the flush is gone before orgasm. 
Using it on an empty stomach is the best. 
if you eat wait\ 4hrs before using it.
go on niacin thread it has lots of information

Oddly enough the early orthomolecular psychiatry researchers (early to mid 70s) published some papers where they say the peak prostaglandin output from niacin consumption occurs after about 3-4 hours.

Who's up for doing that experiment.... waiting those 3 or 4 hrs!!

I would, but I'd fear that it might not work. I don't want more POIS!!

But I assume by your comment that it is the prostaglandin output that is so involved in the process!


Absolutely, that's my belief. Actually, I re-read the paper and in most inflammations (if the niacin flush is like that) the prostaglandin levels would continue to rise past those 3-4 hours. It's a worthwhile experiment for someone to do. I might have a go but I'd have to stop taking ginkgo, gotu kola, b vits and all the other groovy stuff that has me motoring around like I don't have POIS :)

The orthomolecular psychiatrists believed the following based on their test results.

Quote
Of great importance is the fact that prostaglandins not only mediate inflammation and immunity but also limit these processes as well; hence the conclusion: prostaglandins are modulators of in- flammation and immunity. Although the complexities of this operation are beyond our present comprehension, in general it appears that low concentrations are associated with inflammation and high concentrations with inhibition of in- flammatory and immune mechanisms.

So what I'm wondering is does the protective effect actually increase following waiting for a few hours?

Daveman

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Re: Summary of Treatments
« Reply #38 on: August 22, 2012, 03:22:06 PM »
I was wondering if we can change something in the summary treatment of niacin.  Maybe we can add a general procedure on how people are taking it.  eg.  "have an O an hour after flushing"  or maybe a recommended amount to start with if you are first trying it.  I don't take niacin to ofter but I am going to start and I really need to know the general "niacin taking" procedure.

good idea i will get on that.

for time being i believe you use it and wait untill all the flush is gone before orgasm. 
Using it on an empty stomach is the best. 
if you eat wait\ 4hrs before using it.
go on niacin thread it has lots of information

Oddly enough the early orthomolecular psychiatry researchers (early to mid 70s) published some papers where they say the peak prostaglandin output from niacin consumption occurs after about 3-4 hours.

Who's up for doing that experiment.... waiting those 3 or 4 hrs!!

I would, but I'd fear that it might not work. I don't want more POIS!!

But I assume by your comment that it is the prostaglandin output that is so involved in the process!


Absolutely, that's my belief. Actually, I re-read the paper and in most inflammations (if the niacin flush is like that) the prostaglandin levels would continue to rise past those 3-4 hours. It's a worthwhile experiment for someone to do. I might have a go but I'd have to stop taking ginkgo, gotu kola, b vits and all the other groovy stuff that has me motoring around like I don't have POIS :)

The orthomolecular psychiatrists believed the following based on their test results.

Quote
Of great importance is the fact that prostaglandins not only mediate inflammation and immunity but also limit these processes as well; hence the conclusion: prostaglandins are modulators of in- flammation and immunity. Although the complexities of this operation are beyond our present comprehension, in general it appears that low concentrations are associated with inflammation and high concentrations with inhibition of in- flammatory and immune mechanisms.

So what I'm wondering is does the protective effect actually increase following waiting for a few hours?

Come on, who'll try it. maybe someone who has a mediocre response to niacin can see if waiting 3 or 4 hrs after taking the niacin helps relieve symptoms better.

If your present response is mediocre, you don't stand to loose as much if it doesn't work, and if positive, then better results!



WITHOUT RESEARCH THERE WILL BE NO CURE!
Sessions 5 to 9 days, mostly Flu-like, joints, digestion problems, light cognitive.
Niacin has changed my lif though, now 1 day MAX.
Somewhere in this interaction with Niacin is the answer!

Daveman

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Re: Summary of Treatments
« Reply #39 on: August 22, 2012, 03:22:58 PM »
It would also help us refine the theory!

WITHOUT RESEARCH THERE WILL BE NO CURE!
Sessions 5 to 9 days, mostly Flu-like, joints, digestion problems, light cognitive.
Niacin has changed my lif though, now 1 day MAX.
Somewhere in this interaction with Niacin is the answer!

Going less Crazy

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Re: Summary of Treatments
« Reply #40 on: August 22, 2012, 10:38:26 PM »
yes Kurtosis, sadly I don't take the "C" anymore.  I think after taking it for a while it did have a profound affect on my sleep.  Even though I felt pretty good, the sleep was catching up on me.  I think vitamin C stays in the system after taking it a few times in a row. 

I'm not sure if I want to try 3-4 hours after niacin.  It seems like the affects of niacin wouldn't be there, but who knows  ???


???
My POIS managed with modified Paleo Diet (@ diet that 100% manages my pois)Believe my POIS stems from inflammation in the gut. O and stimulation = neuro POIS from inflammation from the gut.

I take <1/4 drop of a 10mg liquid Zyrtec gelcap every night and it has vastly improved my sleep and energy.

Prancer

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Re: Summary of Treatments
« Reply #41 on: August 22, 2012, 11:24:47 PM »
So what I'm wondering is does the protective effect actually increase following waiting for a few hours?

In the past I remember once waiting a very long time after the flush (like 2-3 hours), long enough where I didn't feel any remaining effects from the niacin at all. This seemed to give me much more relief than I have had when I only waited 20 minutes or so after the flush. I'm one of the people that doesn't usually get good results from niacin. It seems to help me in the very short term, but the next day is terrible. But it could also be the number of orgasms I have (I have about 4-7 within the span of about 15 minutes, but only around once a week), which absolutely screws up my cognitive functioning for a few days. So yes, in my case longer waiting is better, although I'm sure there is a time limit when the niacin would eventually wear off.

PS: I still take 1-2g vitamin C along with the other supplements and their doses every day, but don't know if the C has any effect on my POIS (I don't think it does).
« Last Edit: August 22, 2012, 11:27:38 PM by Prancer »
Symptoms (mostly cognitive): brain fog/difficulty thinking, lack of motivation, fatigue, trouble finding the right words, racing thoughts, possible OCD, anxiety, social withdrawal, extreme frustration and irritability, general discomfort.

Born in 1989, and symptoms since I was 14.

kurtosis

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Re: Summary of Treatments
« Reply #42 on: August 23, 2012, 03:30:03 AM »
So what I'm wondering is does the protective effect actually increase following waiting for a few hours?

In the past I remember once waiting a very long time after the flush (like 2-3 hours), long enough where I didn't feel any remaining effects from the niacin at all. This seemed to give me much more relief than I have had when I only waited 20 minutes or so after the flush. I'm one of the people that doesn't usually get good results from niacin. It seems to help me in the very short term, but the next day is terrible. But it could also be the number of orgasms I have (I have about 4-7 within the span of about 15 minutes, but only around once a week), which absolutely screws up my cognitive functioning for a few days. So yes, in my case longer waiting is better, although I'm sure there is a time limit when the niacin would eventually wear off.

PS: I still take 1-2g vitamin C along with the other supplements and their doses every day, but don't know if the C has any effect on my POIS (I don't think it does).

Fascinating result. It's a start but we probably need to repeat it and with more than one person. It could be a few days before I could do it because of the other stuff I have in my system. 

I'm not sure about the C either. it makes me feel quite energetic but the way I'm taking it now is different to how I started taking it.

It will have an inhibitory effect on prostaglandin release in some circumstances so one of the effects I noticed was that if I took it after an O was that it reduced my POIS symptoms.
http://www.ncbi.nlm.nih.gov/pubmed/1492101
This was when I first tried it ages ago. but Prostaglandin has one of those sort of U shaped inflammation effect graphs. If you're using niacin correctly I suspect that you'll have enough prostaglandins in your system that they have the inflammation management effect rather than the inflammation creating effect. In that case, lowering levels with vitamin C, even targeted, might not do much. If you're not using niacin then trying to lower it just after an O might be a good thing.

Anyway, interesting about the niacin.

Daveman

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Re: Summary of Treatments
« Reply #43 on: August 23, 2012, 12:21:57 PM »
So what I'm wondering is does the protective effect actually increase following waiting for a few hours?

In the past I remember once waiting a very long time after the flush (like 2-3 hours), long enough where I didn't feel any remaining effects from the niacin at all. This seemed to give me much more relief than I have had when I only waited 20 minutes or so after the flush. I'm one of the people that doesn't usually get good results from niacin. It seems to help me in the very short term, but the next day is terrible. But it could also be the number of orgasms I have (I have about 4-7 within the span of about 15 minutes, but only around once a week), which absolutely screws up my cognitive functioning for a few days. So yes, in my case longer waiting is better, although I'm sure there is a time limit when the niacin would eventually wear off.

PS: I still take 1-2g vitamin C along with the other supplements and their doses every day, but don't know if the C has any effect on my POIS (I don't think it does).

II have noticed that, if for some reason, I have a hard time getting a flush and have to take more (I do this a bit at a time, so it takes longer to finish the niacin), that I get good results despite the lesser flush. So it could be that in those cases, I wait at least an hour after the taking the niacin, when it's usually 25 minutes.

The other is that it could be that it works even without flush because the flush mechanism is blocked (due to heavier digestion..not having fasted ) yet I have the required amount of niacin in my blood??

WITHOUT RESEARCH THERE WILL BE NO CURE!
Sessions 5 to 9 days, mostly Flu-like, joints, digestion problems, light cognitive.
Niacin has changed my lif though, now 1 day MAX.
Somewhere in this interaction with Niacin is the answer!

Ccconfucius

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Re: Summary of Treatments
« Reply #44 on: August 23, 2012, 07:23:09 PM »
daveman and other successful niacin users what do you think of procedure i wrote any changes you recommend.