Open Microbiome Initiative: сollect POIS gut data and look for common patterns

[Grisha]

Hey everyone,

I?ve been living with POIS for a while, and like many here, I?ve gone deep into theory-hopping, forum diving, and trial-and-error protocols.
I?m a scientist by education and a data analyst by profession.
Recently, I started to suspect that POIS in my case is strongly tied to gastrointestinal imbalance ? particularly gut microbiota composition.

I?ve read the Dysbiosis/SIBO/SIFO references in the POIS hypothesis lists, and I believe it?s time we try to collect actual data to see if something unites us ? or at least a subset of us ? on the microbiome level.

🔍 Here?s what I propose:
Let?s start a crowdsourced microbiome comparison project:

If you?ve done a gut microbiome test (like from Genova, Viome, Atlas Biomed, Genotek, BiomeFx, etc.)

And you?re willing to share anonymized results ? great.

No need to post your name. Just the results (PDF/CSV/screenshot) and some basic metadata, like:

Age / gender

POIS duration

Key symptoms

When test was done

Once I get enough data (even 10?20 samples), I?ll compare it to open-access healthy microbiome databases like HMP, American Gut, GMrepo, etc.

🎯 Goal:
See if there are common microbiome traits in POIS sufferers (e.g., lack of butyrate-producing bacteria, SIBO patterns, high enterobacteria, low diversity, etc.)

Try to define POIS-associated microbial fingerprints that could be tested and tracked

Possibly this info can help someone to find better treatment through targeted pre/pro/postbiotics or even antibiotics or whatever helps.

✅ What I?ll do with the data:
Aggregate and anonymize it

Analyze bacterial abundances and compare across POIS users and healthy controls

Publish results here for open discussion

If there?s interest ? maybe even write a summary report we can share more widely

If you want to share, comment below or DM me. I?ll create a Google Form soon to help structure submissions.

If this sounds interesting to you ? or if you have ideas on how to improve it ? I?d love your input.

Let?s stop guessing in the dark. If the gut plays a role in POIS, the data will show it.

Thanks for reading 🙏

Grisha

[Aladin]

Great initiative !

[Warrior]

Good initiative as Aladin said.

I would suggest to add further testing, specifically organic acid testing (OAT). That’s what I was recommended by specialists and has been the most insightful test done so far re what may be going on with my POIS.

With that being said, I’m sure a gut mapping test would indicate similar dysfunctions.