Author Topic: POIS research  (Read 2208 times)

less_fogged

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Re: Not impressed by POIS research
« Reply #20 on: June 03, 2024, 08:29:32 AM »
Sorry if I'm getting a bit off the topic here but just want to say...

How strange I find it how some report better tolerating a diet rather on carbohydrates or even sugar instead of vegetable and animal based diet, shows how differently our bodies are functioning.

I guess I can only recommend that for each one of us to figure out the best possible ourselves what we can tolerate. Allergy is often an issue in general with our illness. I myself already effected with a list of allergens! And since a few months ago after many years detected that I'm also somehow sensitive to diary products while I was unknowingly ignoring it for a long time!

So for those stuck in a routine to especially consume a lot of carbohydrates or consume a lot of sugar for example I hope you find a way to still get all your vitamins that your body requires as to avoid new issues later on in life!

total

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Re: Not impressed by POIS research
« Reply #21 on: June 03, 2024, 08:41:59 AM »
Have you taken the ige (general) test? All those who have elevated levels need to get together and go on different diets for a week. Some are on milk, others are on keto, the rest are on carbohydrates. Who can do it purely on vegetables.

total

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Re: Not impressed by POIS research
« Reply #22 on: June 03, 2024, 08:50:33 AM »
I tested blood cortisol another 2 or 3 times. It was slightly below normal or on the border of decline. Cortisol also somehow affects allergic and immune reactions.

Warrior

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Re: Not impressed by POIS research
« Reply #23 on: June 03, 2024, 11:45:45 AM »

My symptoms also decreased greatly when I started eating a protein-free diet. I eat pasta, bread, cabbage, etc. I decided to switch to a carbohydrate diet due to the constant presence of protein in my urine. But when I decided to eat meat cutlets, I had a severe allergy in the morning. I think pois is related to the kidneys. I am also severely deficient in vitamin D. And there is grade 1 osteoarthritis in the knees and feet. Do you have osteoarthritis or protein in your urine?

For those that do better on a meat free diet, it may have to do with reducing arachidonic acid (AA), which is an inflammatory pathway Nanna1 mentioned a lot regarding POIS.

AA is only found in animal-foods.
Nothing I say is medical advice. Always do your own research. Follow anything I say at your own discretion.
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total

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Re: Not impressed by POIS research
« Reply #24 on: June 03, 2024, 02:50:13 PM »

My symptoms also decreased greatly when I started eating a protein-free diet. I eat pasta, bread, cabbage, etc. I decided to switch to a carbohydrate diet due to the constant presence of protein in my urine. But when I decided to eat meat cutlets, I had a severe allergy in the morning. I think pois is related to the kidneys. I am also severely deficient in vitamin D. And there is grade 1 osteoarthritis in the knees and feet. Do you have osteoarthritis or protein in your urine?

For those that do better on a meat free diet, it may have to do with reducing arachidonic acid (AA), which is an inflammatory pathway Nanna1 mentioned a lot regarding POIS.

AA is only found in animal-foods.


Maybe, but I got an allergy from a pill that doesn?t contain arachidonic acid. (ethylmethylhydroxypyridine succinate 125 mg
Excipients: lactose monohydrate, povidone K-30, magnesium stearate.

Film shell composition: hypromellose, titanium dioxide, lactose monohydrate, macrogol, triacetin).

total

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Re: Not impressed by POIS research
« Reply #25 on: June 03, 2024, 03:04:05 PM »

My symptoms also decreased greatly when I started eating a protein-free diet. I eat pasta, bread, cabbage, etc. I decided to switch to a carbohydrate diet due to the constant presence of protein in my urine. But when I decided to eat meat cutlets, I had a severe allergy in the morning. I think pois is related to the kidneys. I am also severely deficient in vitamin D. And there is grade 1 osteoarthritis in the knees and feet. Do you have osteoarthritis or protein in your urine?

For those that do better on a meat free diet, it may have to do with reducing arachidonic acid (AA), which is an inflammatory pathway Nanna1 mentioned a lot regarding POIS.

AA is only found in animal-foods.


Maybe, but I got an allergy from a pill that doesn?t contain arachidonic acid. (ethylmethylhydroxypyridine succinate 125 mg
Excipients: lactose monohydrate, povidone K-30, magnesium stearate.

Film shell composition: hypromellose, titanium dioxide, lactose monohydrate, macrogol, triacetin).


I need to try foods with a lot of vegetable protein (beans, lentils), and get tested.

ghayor

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Re: Not impressed by POIS research
« Reply #26 on: June 03, 2024, 04:28:07 PM »
Apparently it's got something to do with the randle cycle. Most junk food and unhealthy food is not carb loaded or fat loaded, its evenly distributed. 50% fat and 50% carbohydrate. A balanced diet as people like to call it.

Keto diet is predominantly fat 90%.
Low fat vegan diet is predominantly carb + protein with fat at less than 5%.

IT seems that these extreme diets where you rely on just one source (fat or carbohydrate) seems to do wonders for POIS.

total

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Re: Not impressed by POIS research
« Reply #27 on: June 03, 2024, 08:07:12 PM »
People wrote what medications helped them.

Propranolol Protein binding 93% Diphenhydramine Plasma protein binding ? 98-99%. Chlorphenamine Plasma protein binding - about 70%
Etapyrazine Phenothiazines are highly bound to plasma proteins.
Prednisolone Reduces the number of circulating lymphocytes (T- and B-cells), has a pronounced dose-dependent effect on the metabolism of carbohydrates, proteins and fats. Benzodiazepines Alzolam
About 80% of the drug binds to plasma proteins.
Niacin is mainly needed for: ? metabolism of fats and carbohydrates and protein synthesis.

The problem is with proteins, the question is which ones? Allergy is also protein.

ghayor

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Re: Not impressed by POIS research
« Reply #28 on: June 03, 2024, 08:32:30 PM »
hey Total, check out Walter Kempner and his diet that he used to cure patients of diabetes and kidney disease. He theorized that kidney disease could be avoided and healed by reducing the protein intake and sodium intake of the patient.


total

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Re: Not impressed by POIS research
« Reply #29 on: June 03, 2024, 09:34:26 PM »
hey Total, check out Walter Kempner and his diet that he used to cure patients of diabetes and kidney disease. He theorized that kidney disease could be avoided and healed by reducing the protein intake and sodium intake of the patient.


A good diet, but dried fruits don?t really suit me, and neither do apples. I would like to find the reason for ige and that?s it. What protein increases it for me? Because my ige is like an elevator going up and down, and I noticed that food plays a role here. After masturbation, ige did not change at all. Sperm also consists of 90% protein.

Sisyphus

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Re: POIS research
« Reply #30 on: December 01, 2024, 08:15:03 AM »
What would I like to see from pois research?

I am very interested in the professional POIS research project by NORD and also the likes of The University of Chicago. As well as these, something else I would really like to see is a pois forum internal research project conducted by the people who really matter here, all of us suffering from pois. It seems to me there is a big opportunity there to do this.  Imagine how useful it would be to have a growing db with test results of 100s of poisers, successful treatment plans etc, which would link up the valuable information which is currently in forum posts. I think it would combine really well with the professional research. Pros and Cons of course, but overall, I think potentially it would be Gold.

This forum has been here a long time before I joined it so maybe this idea has already been discussed/attempted/thrown out previously?
« Last Edit: December 01, 2024, 11:28:57 AM by demografx »

demografx

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Re: POIS research
« Reply #31 on: December 01, 2024, 10:09:36 AM »
What would I like to see from pois research?

I am very interested in the professional POIS research project by NORD and also the likes of The University of Chicago. As well as these, something else I would really like to see is a pois forum internal research project conducted by the people who really matter here, all of us suffering from pois. It seems to me there is a big opportunity there to do this.  Imagine how useful it would be to have a growing db with test results of 100s of poisers, successful treatment plans etc, which would link up the valuable information which is currently in forum posts. I think it would combine really well with the professional research. Pros and Cons of course, but overall, I think potentially it would be Gold.

This forum has been here a long time before I joined it so maybe this idea has already been discussed/attempted/thrown out previously?

Excellent thoughts!

Keep in mind that POIS sufferers WILL be studied - - in the UCLA laboratory - - and afterwards!
« Last Edit: December 01, 2024, 11:32:34 AM by demografx »
10 years of significant POIS-reduction, treatment consisting of daily (365 days/year) testosterone patches.

TRT must be checked out carefully with your doctor due to fertility, cardiac and other risks.

40+ years of severe 4-days-POIS, married, raised a family, started/ran a business