Completely cured of POIS for 2 years

[Iwillbeatthis]

Do you think this Ox (animal) bile supplement could help?! https://nutriest.eu/products/ox-bile-supplement/?_kx=nrNXUZlcnLnTPRIkqkH9HUDEYcPUviWAP16ZL2Ahr1EMNsl7mq1wWQVjGkPnHFox.WNJbcj

Be careful

Ox Bile 500 mg from Nutricology gave me GI distress. Had some kind of pulsating cramps at the height of the stomach for at least 30 min. The dose is probably too high for me or I just cannot tolerate the stuff. I have only used it once.

I was not aware of this:
Activation of mast cells by bile acids:
https://www.sciencedirect.com/science/article/abs/pii/001650859190024F

Basically means your bile is toxic if you can't tolerate them, bile supplements used to cause me major issues too but not anymore. They cause your liver to release more bile.

[marrtintintin]

confirmed, the bile supplement doesn't seem to do me good. It triggers my symptoms

[benoluxuryrentals]

This is motivating. I work in helicopter tours company and my work is sometimes stressful and dealing with POIS is not good. I hope I will follow your experience and get rid of it. Thanks

[marrtintintin]

some poiser have low or high testosterone -> testicular glands
(and some with low testosterone seems to have  some results  reducing POIS symtoms with testosterone replacement therapy.)

some poiser have low or high cortisol -> adrenal glands (this is my case)

some poiser have low or high t3 / t4 -> thyroid glands ( Iwillbeatthis's and marrtintintin's case)
Iwillbeatthis seems to have some result  reducing POIS symtoms treating  thyroid

but what do all these glands have in common ?
answer : hypothalamus/pituary

hypothalamus gives orders to other glands with -> acth, tsh, gh, etc ...
then the differents glands produce testosterone, thyroid hormones, cortisol, etc ...

so all those hormonal problems (that seem common to a lot of poiser and maybe the origin of POIS) could come from a specific gland but maybe our gland is ok and the problem could come from the hypothalamus on a higher level or maybe both.
thats why sometimes treat the gland gives some result reducing POIS symptoms but not always 100%

there could be many reason why our glands or hypothalamus would be defective but the main reason would be chronic/traumatic stress (a lot of poiser seems sensitiv to stress) or intoxication that tires or disrupts the glands.

but before focus on why we need to know which.

so for any new poiser my suggestion would be to do a blood test to check all this hormones before and after an orgasm to identify which hormones/ glands seems to be defective.
blood test : acth, tsh, gh, somatomedins, prl, fsh, lh, msh, oxytocin, adh, epinephrine, norepinephrine, cortisol, corticosterone, t3, t4, inhibin, testosterone,

note that as i tried to explain in my case (https://poiscenter.com/forums/index.php?topic=4556.msg48987#msg48987)
there could be many reasons why some of us could still have normal level for a hormone.
that's why doing a blood test after an orgasm even if it would be such a pain could be really helpfull to see clearer.
since an orgasm seems to break everything, a blood test after orgasm could  reveal more thing.

Hey largoo, thank you so much for your interesting post. It does make a lot of sense—the hypothalamus and "traumatic stress". What you describe makes a lot of sense for me. I wonder what to do with this informaiton, and what would help curing the hypothalamous and not reacting to stress like this.

[marrtintintin]

Do you think this Ox (animal) bile supplement could help?! https://nutriest.eu/products/ox-bile-supplement/?_kx=nrNXUZlcnLnTPRIkqkH9HUDEYcPUviWAP16ZL2Ahr1EMNsl7mq1wWQVjGkPnHFox.WNJbcj

Be careful

Ox Bile 500 mg from Nutricology gave me GI distress. Had some kind of pulsating cramps at the height of the stomach for at least 30 min. The dose is probably too high for me or I just cannot tolerate the stuff. I have only used it once.

I was not aware of this:
Activation of mast cells by bile acids:
https://www.sciencedirect.com/science/article/abs/pii/001650859190024F

Basically means your bile is toxic if you can't tolerate them, bile supplements used to cause me major issues too but not anymore. They cause your liver to release more bile.

I thought that if the problem was bile liquid, maybe it would be good to supplement it. I don' fullyt understand why it increases my pois. I mean, I will beat this, you did mention that our bile is toxic, I just don't fully understand how our bile is toxic. 

[marrtintintin]

Tonight, I was feeling a bit of pain in my left lower back, and I had two wet dreams in one night! and every time I had wet dreams, I felt this pain in my left lower back.
I know that I will beat this realise that probably it is not the kidneys causing the problem and that it is rather the liver, bile ducts and gall bladder. And it makes sense. I have also always thought that it was the kidneys who were responsible, but since tonight having this pain on the left side, I am reconsidering that kidneys still play a part in this. I mean, I think the right side was also hurting a little bit, but mostly I was feeling the right side.
also, usually, I have these pains when digestion doesn't work well. when the stomach feels stuck and there is this lower back pain. then I get a wet dream, dk why...

[largooo]

do you have lower back pain also when you are stress or only when pois/wet dream/bad digestion ?

[demografx]

So in 2021 I was having bad pain on my right side which I thought was my kidney at the time but whenever I ate things like steak I would get pain on this side. It was never my kidney it was my liver, bile ducts and gallbladder struggling.

I had been dealing with a stomach ulcer on and off for 6 months, one day at start of 2022 it flared up again quite badly, I also caught covid or something quite badly from my brother (he had a bad chest infection), after about a week I recovered from this virus or whatever it was, but one day I was eating a burger and suddenly I get a sharp pain in my upper right quadrant, I then proceeded to have the fastest heart rate I've ever felt in my life, chest pain, chills, losing consciousness, breathlessness it felt like a heart attack and I felt my life flash before my eyes. Anyway my brother called the ambulance really worried, but I had a grounding mat at home I somehow managed to connect myself to and this seemed to recover me some how and I didn't feel like was dying anymore. The ambulance people still came and I could barely speak to them I was in so much shock. I found this study afterwards Conclusions: Grounding increases the surface charge on RBCs and thereby reduces blood viscosity and clumping. Grounding appears to be one of the simplest and yet most profound interventions for helping reduce cardiovascular risk and cardiovascular events.

https://www.liebertpub.com/doi/full/10.1089/acm.2011.0820#:~:text=Conclusions%3A%20Grounding%20increases%20the%20surface,cardiovascular%20risk%20and%20cardiovascular%20events.

I go to the hospital and get discharged,  but when I get back homeI take one bite of food and I suddenly get a similar feeling like I was about to die again, severe wave like contraction pain in abdomen like it was about to rupture, super fast heart rate and just felt really bad. And never once with my 7-8 years of health issues did it ever feel life threatening until this time. So all I could do was lay flat on my back deep breathing praying I would survive. But for 3 days I couldn't eat any food without these life threatening symptoms occurring and I could barely walk around the house without feeling really bad. So I wondered if my stomach ulcer was bleeding or had my stomach ruptured. After 3 days I managed to get Pepcid (famotidine) from my GP and I could finally eat without it feeling life threatening. I had to slowly build up the foods I could eat otherwise I would get set back to square one so started with rice and eggs, but when i tried something like chicken or tortilla chips I would get set back to where it felt life threatening again. My blood pressure was also going from super high to super low during this time. The best the GP could do was refer me to a gastroenterologist  in 3 months time and A&E were useless in providing any investigation (with scans/colonoscopy etc) even though I had blood in my stool and coughing up blood at times. So I had to take matters into my own hands as the situation seemed very dangerous, I heard bpc157 had caused rapid healing of ulcers for people so i ordered some and it was helpful for making the cardiovascular symptoms went away with it but I still wasn't healed. Then I tried this grass fed yogurt and it seemed to heal my gut and everything like crazy and finally felt like I was at a point where I would be able to eat and get on with life normally again. Then one day I had a digestive enzyme supplement with my food and suddenly my gallbladder just gave up on me and from that point on I would very clearly have gallbladder pain and spasms when I tried to eat fatty food or eggs. So it was clear to me the whole health crisis happened because of my gallbladder going wrong but it took a while for it to finally give up and stop working properly.

Anyway from this point on I was constantly have gallbladder attacks, I could barely eat any foods anymore, I was having fever like symptoms but no temperature, had the chills, very low and high blood pressure, pale stools. So I had some form of cholestasis. I did some blood tests and it showed I was hypothyroid very low T3, ultrasound showed a gallstone I had had doubled in size fro 0.5cm to 1cm in 6 months. So I did everything I could to try and heal my gallbladder TUDCA, bean protocol, stone breaking supplements but I wasn't actually healing anything and still in a lot of pain. Then someone told me they healed their gallbladder with Dr Wilsons diet, so I tried that but my own version of it which was lots of pressure cooked carrots, butternut squash, celery, with animal protein and a bit of nut butter and no sulfur veg because I couldn't tolerate sulfur at the time. I felt amazing on the diet and my autistic symptoms and vitality was a lot better etc (I think I did still have POIS at this time I remember) but I was turning orange from this diet and had severe blood sugar issues, if I tried to eat fruit or fruit juice or any sugar I would have severe blood sugar symptoms such as bad neuropathy, numb tongue, feeling like I would pass out if I walked down street, my gallbladder issues were still present and didn't feel healed. I was eating 8-10 carrots a day, 1/2-1 whole butternut squash so I was way overdosing on provitamin A (beta carotene). One day I took TUDCA and nattokinase with my high beta carotene meal and my stomach was very inflamed and I felt very fragile and ill again. This was about 30 days after I had been doing the diet. After this happened the skin on roof of my mouth peel off whenever I tried to eat carrots, pancreas pain, itchy skin and liver pain. I then found out about Vitamin A toxicity and Dr Garret Smith's and Grant Genereuxs work about Vitamin A toxicity being the root cause autoimmune disease and cholestasis, diabetes etc and my symptoms all made sense.

So I followed their advice and went very low Vit A and I felt awful (much worse than before I started low Vit A), had bad headaches, neuropathy all over body, rashes, extreme anxiety, all my autistic symptoms came flooding back, numb genitals. And when I tried to go back to eating carrots I also felt bad and had liver pain itchy skin etc. So I was trapped on this new diet where I felt worse. I was eating this organic sourdough bread which I now think had glyphosate but when I cut it out a lot of the severe symptoms went away. Anyway on this low Vit A I could now eat sugar again without the terrible blood sugar symptoms, my bowels were much more regular as it was fixing my bile and cholestasis (Vit A toxicity in liver impairs bile and causes a subclinical cholestasis), my skin colour was returning to normal. My POIS completely went on low Vit A diet I had 0 POIS anymore and 0 POIS since then. This Dr Garret smith guy also thinks that ejaculation causes a toxic bile dump and this is why people don't feel great after ejaculation and that makes sense to me

If you are regularly eating a lot of carrots, butternut squash, liver, dairy, cod liver oil, fish oil or have taken accutane in the past I would definitely check out this Vitamin A toxicity stuff. If your stools aren't dark brown and are more light coloured eg : tan then it means you have some form of subclinical cholestasis + your bile isn't working properly so again I would check out the low Vit A detox.

If you have SIBO then you have bile issues, the second bile is flowing strongly in the right direction there is no SIBO, bile is our own natural and strongest antimicrobial. A lot of people take stuff to get rid of their SIBO like antimicrobials but it usually comes back, why? Because they never fixed the root cause of the issue which is poor bile production/flow.

https://www.youtube.com/watch?v=ckzs7Q9c_8k&t=2175s&ab_channel=ElwinRobinson
https://www.youtube.com/watch?v=8GxCoUfaB8c&t=197s&ab_channel=NutritionDetective
 - Check Toxic bile theory and Vitamin A toxicity in these two videos

https://ggenereux.blog/my-ebooks/ - Grant Genereux's books about Vitamin A toxicity being the root cause of autoimmune diseases, a lot of people have healed their autoimmune and health issues going on a low Vit A diet

https://pubmed.ncbi.nlm.nih.gov/20233723/ - Fat soluble Vitamins shut down your toxic bile production (this can make you feel better in the short term but cause major issues in the long run) Low Vit D levels in blood usually is a sign of Vitamin A toxicity in the liver people who on low Vit A diet raise their Vit D levels without having to take Vit D supplements.  Vit A and Vit D are antagonistic to each other

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392079/ - Professor Anthony Mawson thinks Covid causes liver damage and this triggers the "retinoid cascade" in the liver that causes liver damage and cholestasis which leads to leakage of toxic retinoid compounds into the blood (retinoic acid and retinyl esters) that are responsible for tissue and organ damage in people who get covid. I believe this might be what happened to me as I took astanxthain (very high in cartoenoids/provitamin A) 3 days before this heart attack event happened.

Basically when you go very low Vit A your liver starts dumping all kinds of toxins it was previously holding onto and your bile flow normalises, when before your toxic bile would be leaking out of your liver into your blood and causing symptoms.

The basics of Vit A detox are going pretty low Vit A in diet, having a soluble fiber source (can be beans, oats) to bind to the toxic bile and get it out of the body as your bile flow and cholestasis slowly fixes itself (you can also use pectasol or charcoal as bile binders), copper antagnoists zinc, molybednum, selenium to bind to copper coming out of liver, make sure you're getting sufficient potassium, magnesium so your detox enzymes are running correctly, lactoferrin to heal damaged epithelial cells and bile ducts. Flush Niacin is also used as NAD is needed to run the ALDH and ADH enzymes needed to detox Vitamin A (zinc, magnesium and molybdenum are also needed for these enzymes).

I didn't just do low Vit A I also did daily coffee enemas for 6 months as my gallbladder was really bad and these made a huge difference for eliminating toxic bile from my bile ducts and liver. I would say the daily coffee enemas is what really fixed my issues as they really clean out the liver of toxicity. I also used pectasol and glycine before the enemas and these made me dump burning yellow bile from the liver (I guess was heavy metals or Vitamin A I'm not sure) and mega igg 2000 was also helpful in the enemas for repairing the gut.

Make sure you get enough potassium I ate pressure cooked low Vit A veg so white parsnips, cauliflower all organic.

Do not eat a high PUFA diet when you have POIS, PUFA inhibits the thyroid and causes hypoxia (low oxygen availability  to cells).

  isn't better to tell your abstract  first  and then  elaborate your story?

Why are you responding to this just now, when he posted it well over 8 months ago?

[marrtintintin]

do you have lower back pain also when you are stress or only when pois/wet dream/bad digestion ?

I generally have this pain, which seems to be related to the ileocecal valve.which becomes congested and creates the pain in the right lower back bcs of the nerves there.
The fun fact is that when this pain is most acute, then i get a wet dream.

The ileocecal valve dysfunction could be responsible to our digestion (and mind issues).

Do you guys feel this disconfort in the right lower back?

[Andre2505]

Yes bit when i do exercise, sorry im italian. (Quando faccio sforzi o movimenti errati ho auesto dolore nella parte bassa della schiena a destra)