Author Topic: I think I found the cause of my POIS: Problems with the androgen receptors  (Read 125 times)

xeon

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When I do different things that upregulate androgen receptors* my POIS is milder, like just a few hours of feeling a bit drunk. Nothing that some Humic acid cannot fix (it boosts the immune system ;)). And the next day I'm OK like I never O the previous day.

I also notice eating sweets make things worse. Sweets themsleves were shown to lower T levels:

https://www.diabetes.co.uk/news/2016/sep/men-experience-an-abrupt-decrease-in-testosterone-levels-after-sugar-intake,-study-finds-99746064.html

I've noticed avoiding seets help with my T levels and also overally feeling masculine. When I consume too many sweets I start acting and feeling kinda effeminate and my confidence diminishes in addition to making my POIS worse.

*L-carnitine and resistance training

I am actually high T but my SHBG was dx as too high and I had symptoms of low T despite having high T like putting too much fat and losing body hair. Also some citation:

"There might be plenty of testosterone in the blood but without active receptors, the symptoms of an androgen insufficiency may still occur:

Increased body fat around abdomen
Fatigue

Reduced libido
Loss of body hair
Hot flushes and sweating
Lethargy
Depression

Increased risk of insulin deficiency
Weaker bones and increased risk of osteoporosis"
I basically had all of the bolded. :)

The androgen receptors POIS connection must be studied more thoroughly.

JayDeeSee

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Re: I think I found the cause of my POIS: Problems with the androgen receptors
« Reply #1 on: September 16, 2022, 04:37:45 PM »
You might be onto something. I have little doubt that some combo of androgen/neurotransmitter/hormone is behind this.

I'd like to hear more about your humic acid use

xeon

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Re: I think I found the cause of my POIS: Problems with the androgen receptors
« Reply #2 on: September 23, 2022, 05:41:22 AM »
Yes, I can confirm it for sure now. I Od yesterday and while I had a small flare for about a few hours it disappeared after doing some pull ups in the park and taking a huge dose of a supplement said to boost androgen receptor sensitivity. I know it's the androgen receptors as I got hairier chest, arms and legs at age 33!